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The map label for this gene is arnA [H]

Identifier: 126452402

GI number: 126452402

Start: 2263797

End: 2264822

Strand: Direct

Name: arnA [H]

Synonym: BURPS1106A_2278

Alternate gene names: 126452402

Gene position: 2263797-2264822 (Clockwise)

Preceding gene: 126452558

Following gene: 126453270

Centisome position: 56.76

GC content: 62.28

Gene sequence:

>1026_bases
GTGAACGGCTTCATCGGTCATCACCTGTCCAAGCGCATTCTTGAAACCACCGATTGGGAAGTGTTCGGCATGGACATGCA
GACCGACCGGCTCGGCGATCTCGTCAAGCACGAGCGGATGCATTTCTTCGAAGGCGACATCACGATCAACAAGGAGTGGG
TCGAGTATCACGTGAAGAAGTGCGACGTGATCCTGCCGCTCGTCGCGATCGCGACGCCCGCCACCTACGTCAAACAGCCG
CTGCGCGTGTTCGAGCTCGACTTCGAGGCGAACCTGCCGATCGTGCGCTCGGCCGTCAAGTACGGCAAGCATCTCGTGTT
TCCGTCGACGTCCGAGGTCTATGGCATGTGCGCGGACGAGCAGTTCGACCCGGATGCGTCCGCCCTCACCTACGGCCCGA
TCAACAAGCCGCGCTGGATCTACGCGTGCTCGAAGCAACTGATGGACCGCGTGATCTGGGGCTACGGGATGGAAGGCCTG
AACTTCACGCTGTTCCGCCCGTTCAACTGGATCGGCCCGGGCCTCGACTCGATCTACACGCCGAAGGAAGGCAGCTCGCG
CGTCGTCACGCAGTTCCTCGGCCACATCGTGCGCGGCGAGAACATCAGCCTCGTCGACGGCGGCTCGCAAAAGCGCGCGT
TCACGTACGTCGACGACGGCATCAGCGCACTGATGAAGATCATCGAGAATTCGAACGGCGTCGCGACGGGCAAGATCTAC
AACATCGGGAATCCGAACAATAACTTCTCGGTGCGCGAACTCGCGAACAAGATGCTCGAGCTCGCGGCGGAGTTCCCCGA
GTACGCCGATTCGGCCAAGCGCGTGAAGCTCGTCGAGACGACCTCGGGCGCGTACTACGGCAACGGCTATCAAGACGTGC
AGAACCGCGTGCCGAAGATCGAGAACACGATGCAGGAGCTCGGCTGGGCACCGCAGTTCACGTTCGACGACGCGCTGCGC
CAGATCTTCGAGGCGTACCGCGGCCACGTCGCCGACGCGCGCGCGCTCGTCGAGCAGCACGGCTGA

Upstream 100 bases:

>100_bases
CGCACGACGGCGGCGAAGCCGTCGTTTCCCCGGCGCAATTCGCGCAGTTCATTCATTCTTCCCGTCATTCATGAAAGCAA
AAAAAGTCCTGATCCTGGGT

Downstream 100 bases:

>100_bases
GCGGGGCCCACCGCTTGGCTCGCATCGTCCTCAAGATCGACGTCGACACGTTGCGCGGCACGCGCGAAGGCGTGCCGAAC
CTCGCGCGCATCTTCGATCG

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVKHERMHFFEGDITINKEWVEYHVKKCDVILPLVAIATPATYVKQP
LRVFELDFEANLPIVRSAVKYGKHLVFPSTSEVYGMCADEQFDPDASALTYGPINKPRWIYACSKQLMDRVIWGYGMEGL
NFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTYVDDGISALMKIIENSNGVATGKIY
NIGNPNNNFSVRELANKMLELAAEFPEYADSAKRVKLVETTSGAYYGNGYQDVQNRVPKIENTMQELGWAPQFTFDDALR
QIFEAYRGHVADARALVEQHG

Sequences:

>Translated_341_residues
MNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVKHERMHFFEGDITINKEWVEYHVKKCDVILPLVAIATPATYVKQP
LRVFELDFEANLPIVRSAVKYGKHLVFPSTSEVYGMCADEQFDPDASALTYGPINKPRWIYACSKQLMDRVIWGYGMEGL
NFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTYVDDGISALMKIIENSNGVATGKIY
NIGNPNNNFSVRELANKMLELAAEFPEYADSAKRVKLVETTSGAYYGNGYQDVQNRVPKIENTMQELGWAPQFTFDDALR
QIFEAYRGHVADARALVEQHG
>Mature_341_residues
MNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVKHERMHFFEGDITINKEWVEYHVKKCDVILPLVAIATPATYVKQP
LRVFELDFEANLPIVRSAVKYGKHLVFPSTSEVYGMCADEQFDPDASALTYGPINKPRWIYACSKQLMDRVIWGYGMEGL
NFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTYVDDGISALMKIIENSNGVATGKIY
NIGNPNNNFSVRELANKMLELAAEFPEYADSAKRVKLVETTSGAYYGNGYQDVQNRVPKIENTMQELGWAPQFTFDDALR
QIFEAYRGHVADARALVEQHG

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=332, Percent_Identity=25.9036144578313, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI7657641, Length=339, Percent_Identity=22.7138643067847, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788589, Length=333, Percent_Identity=52.5525525525526, Blast_Score=366, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17539532, Length=335, Percent_Identity=23.8805970149254, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21356223, Length=337, Percent_Identity=23.1454005934718, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 38568; Mature: 38568

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVKHERMHFFEGDITINKEWVEYHVKK
CCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHEEECCEEECHHHHHHHHHH
CDVILPLVAIATPATYVKQPLRVFELDFEANLPIVRSAVKYGKHLVFPSTSEVYGMCADE
HHHHHHHHHHHCCHHHHHCCHHEEEECCCCCCHHHHHHHHHCCEEECCCCHHHHEECCCC
QFDPDASALTYGPINKPRWIYACSKQLMDRVIWGYGMEGLNFTLFRPFNWIGPGLDSIYT
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCC
PKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTYVDDGISALMKIIENSNGVATGKIY
CCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEEE
NIGNPNNNFSVRELANKMLELAAEFPEYADSAKRVKLVETTSGAYYGNGYQDVQNRVPKI
ECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCCCCCCHHHHHHCCCHH
ENTMQELGWAPQFTFDDALRQIFEAYRGHVADARALVEQHG
HHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVKHERMHFFEGDITINKEWVEYHVKK
CCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHEEECCEEECHHHHHHHHHH
CDVILPLVAIATPATYVKQPLRVFELDFEANLPIVRSAVKYGKHLVFPSTSEVYGMCADE
HHHHHHHHHHHCCHHHHHCCHHEEEECCCCCCHHHHHHHHHCCEEECCCCHHHHEECCCC
QFDPDASALTYGPINKPRWIYACSKQLMDRVIWGYGMEGLNFTLFRPFNWIGPGLDSIYT
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCC
PKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTYVDDGISALMKIIENSNGVATGKIY
CCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEEE
NIGNPNNNFSVRELANKMLELAAEFPEYADSAKRVKLVETTSGAYYGNGYQDVQNRVPKI
ECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCCCCCCHHHHHHCCCHH
ENTMQELGWAPQFTFDDALRQIFEAYRGHVADARALVEQHG
HHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA