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The map label for this gene is sucD [H]

Identifier: 126452387

GI number: 126452387

Start: 803266

End: 804195

Strand: Direct

Name: sucD [H]

Synonym: BURPS1106A_0818

Alternate gene names: 126452387

Gene position: 803266-804195 (Clockwise)

Preceding gene: 126451915

Following gene: 126453641

Centisome position: 20.14

GC content: 64.09

Gene sequence:

>930_bases
ATGGCGGCGCGGTTTTTCTCGCGACGCCGATCGAACAGAGGTCATTACATGTCGATTCTGATCAACAAAGACACGAAGGT
CATCACGCAGGGCATCACCGGCAAGACCGGCCAGTTCCACACGCGCGCCTGCCGTGAATATGCAAACGGCCGCGAAGCGT
TCGTCGCGGGTGTGAACCCGAAGAAGGCCGGCGAAGATTTCGAAGGCATTCCGATCTACGCGAGCGTCAAGGAAGCGAAG
GCGGAAACCGGCGCGACCGTGTCGGTCATCTACGTGCCGCCGGCGGGCGCCGCCGCGGCGATCTGGGAAGCGGTCGAAGC
CGATCTCGATCTCGCGATTTGCATCACGGAAGGCATTCCCGTTCGCGACATGATCGAAGTGAAGGACCGCATGCGCCGCG
AAGGCCGCAAGACGCTGCTGCTCGGGCCGAACTGCCCGGGCACGATCACGCCGGACGAACTGAAGATCGGCATCATGCCG
GGCCACATCCACCGCAAGGGCCGTATCGGCGTCGTGTCGCGCTCGGGCACGCTGACGTATGAAGCCGTCGCGCAACTGAC
GGCGCTCGGCCTCGGCCAGTCGTCGGCGGTCGGCATCGGCGGCGATCCGATCAACGGTCTGAAGCACATCGACGTGATGA
AGATGTTCAACGACGATCCGGACACGGATGCCGTCGTGATGATCGGCGAAATCGGCGGCCCGGACGAAGCGAACGCCGCT
CAGTGGATCAAGGACAACATGAAGAAGCCCGTCGTCGGCTTCATCGCGGGCGTCACGGCGCCTCCGGGCAAGCGCATGGG
CCACGCCGGCGCGCTGATCTCGGGCGGTGCGGATACGGCCGAAGCGAAGCTGGAAATCATGGAAGCGTGCGGCATCACGG
TCACGCGCAATCCGTCGGAGATGGGCCGCCTGCTGAAGGCAGCGCTGTAA

Upstream 100 bases:

>100_bases
AGTAAGAGCGCCCGCGCCCGGCGCTTGGCGCCGGGCCCCCGAAGCGGGGCGGGAAGACTCGGGGCAGCCCGCGTTTTTCC
GAGCGCAACATTGAACACGC

Downstream 100 bases:

>100_bases
GCATCGGTTTCATCGCCGCAAAAAACGCCGGTTCCGCCGGCGTTTTTTGTTATGCTCGCGCAATCCTTTCGTCAGCCCCG
CGTCGGGCTGGCCGGCAAGA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAARFFSRRRSNRGHYMSILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKKAGEDFEGIPIYASVKEAK
AETGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGRKTLLLGPNCPGTITPDELKIGIMP
GHIHRKGRIGVVSRSGTLTYEAVAQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAA
QWIKDNMKKPVVGFIAGVTAPPGKRMGHAGALISGGADTAEAKLEIMEACGITVTRNPSEMGRLLKAAL

Sequences:

>Translated_309_residues
MAARFFSRRRSNRGHYMSILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKKAGEDFEGIPIYASVKEAK
AETGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGRKTLLLGPNCPGTITPDELKIGIMP
GHIHRKGRIGVVSRSGTLTYEAVAQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAA
QWIKDNMKKPVVGFIAGVTAPPGKRMGHAGALISGGADTAEAKLEIMEACGITVTRNPSEMGRLLKAAL
>Mature_308_residues
AARFFSRRRSNRGHYMSILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKKAGEDFEGIPIYASVKEAKA
ETGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGRKTLLLGPNCPGTITPDELKIGIMPG
HIHRKGRIGVVSRSGTLTYEAVAQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAAQ
WIKDNMKKPVVGFIAGVTAPPGKRMGHAGALISGGADTAEAKLEIMEACGITVTRNPSEMGRLLKAAL

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=299, Percent_Identity=53.8461538461538, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI38569421, Length=208, Percent_Identity=30.2884615384615, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI38569423, Length=208, Percent_Identity=30.2884615384615, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1786949, Length=293, Percent_Identity=54.9488054607508, Blast_Score=315, Evalue=2e-87,
Organism=Escherichia coli, GI1786513, Length=185, Percent_Identity=28.1081081081081, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17550194, Length=312, Percent_Identity=52.2435897435897, Blast_Score=306, Evalue=9e-84,
Organism=Caenorhabditis elegans, GI17553126, Length=296, Percent_Identity=53.3783783783784, Blast_Score=296, Evalue=8e-81,
Organism=Caenorhabditis elegans, GI17557344, Length=312, Percent_Identity=26.2820512820513, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551266, Length=254, Percent_Identity=26.3779527559055, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324716, Length=296, Percent_Identity=48.3108108108108, Blast_Score=266, Evalue=3e-72,
Organism=Drosophila melanogaster, GI21356559, Length=310, Percent_Identity=47.741935483871, Blast_Score=285, Evalue=2e-77,
Organism=Drosophila melanogaster, GI28574296, Length=306, Percent_Identity=52.6143790849673, Blast_Score=277, Evalue=7e-75,
Organism=Drosophila melanogaster, GI281363477, Length=253, Percent_Identity=26.8774703557312, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281363475, Length=253, Percent_Identity=26.8774703557312, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281363473, Length=253, Percent_Identity=26.8774703557312, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 32760; Mature: 32629

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARFFSRRRSNRGHYMSILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNP
CCCHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCC
KKAGEDFEGIPIYASVKEAKAETGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIP
HHCCCCCCCCEEEEEHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCC
VRDMIEVKDRMRREGRKTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSGTLTY
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCCHH
EAVAQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAA
HHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHH
QWIKDNMKKPVVGFIAGVTAPPGKRMGHAGALISGGADTAEAKLEIMEACGITVTRNPSE
HHHHHCCCCCHHHHEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEECCHHH
MGRLLKAAL
HHHHHHHCC
>Mature Secondary Structure 
AARFFSRRRSNRGHYMSILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNP
CCHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCC
KKAGEDFEGIPIYASVKEAKAETGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIP
HHCCCCCCCCEEEEEHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCC
VRDMIEVKDRMRREGRKTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSGTLTY
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCCHH
EAVAQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAA
HHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHH
QWIKDNMKKPVVGFIAGVTAPPGKRMGHAGALISGGADTAEAKLEIMEACGITVTRNPSE
HHHHHCCCCCHHHHEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEECCHHH
MGRLLKAAL
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]