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The map label for this gene is yfcG [H]

Identifier: 126452319

GI number: 126452319

Start: 3326617

End: 3327315

Strand: Reverse

Name: yfcG [H]

Synonym: BURPS1106A_3409

Alternate gene names: 126452319

Gene position: 3327315-3326617 (Counterclockwise)

Preceding gene: 126452759

Following gene: 126454313

Centisome position: 83.42

GC content: 66.95

Gene sequence:

>699_bases
ATGATCGATCTCTACTACTGGACGACGCCGAACGGCCACAAGATCACGATGTTCCTGGAGGAGGCGGGCCTGCCGTACCG
GATCGTGCCGGTGAACATCGGCCGCGGCGAGCAATTCGAGCCGGCGTTCCTGCGCATCGCGCCGAACAACCGGATTCCCG
CGCTCGTCGACCACGCGCCCGCCGACGGCGGCGCGCCGCTGTCGATCTTCGAATCGGGCGCGATCCTGCTGTACCTCGCG
GACAAGCTCGGGCGCTTCATTCCCGCCGATCTGCGCGGCCGCAACGAGGCGCTGCAGTGGTTGTTCTGGCAGATGGGCGG
GCTCGGCCCGATGGCGGGGCAGAACCATCATTTCGTGCAGTACGCGCCCGAGCCGCTGCCGTATGCGATCGAGCGGTACG
TGAAGGAGACGTCGCGGTTGTACGGCGTGCTGAACAAGCATCTGTCGGACGGGCGCGACTACATCGCGGGCGAATATTCG
ATCGCCGACATGGCGAGCTACCCGTGGATCGTGCCGCACGAGCGGCAGCGGCAGCGTCTCGAGGATTTTCCATTCCTGGC
CGCATGGTTCGCGCGGGTCGCCGAACGGCCGGGCACCGTGCGCGCCTATGCACGGGCGAAGGAGATCAACACGGCGCCGA
CGGTCGATCAGCAGTCGCGCGGCGTGTTGTTCGGGCAGGACGCGAGCACGGTCCGCTGA

Upstream 100 bases:

>100_bases
CGCCATGCGTTCAAGGTCGAGTTCGACGACGAGGCTCGCCGCGCGCTGTTTCCGCAGAACGCGCGGCTCGCGGCCACGGC
CGGGACGGGAGCCTGACGCG

Downstream 100 bases:

>100_bases
CAGGGGACTGGGCGGTCGGCGGGCTTCGGCCCGGCCGCCGCCGTGCGGGCGCGGTCGGGCGCGGGCGCGCCGCGCAACGG
GGCGGGCTCCGGCCCGGCCC

Product: putative glutathione S-transferase

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MIDLYYWTTPNGHKITMFLEEAGLPYRIVPVNIGRGEQFEPAFLRIAPNNRIPALVDHAPADGGAPLSIFESGAILLYLA
DKLGRFIPADLRGRNEALQWLFWQMGGLGPMAGQNHHFVQYAPEPLPYAIERYVKETSRLYGVLNKHLSDGRDYIAGEYS
IADMASYPWIVPHERQRQRLEDFPFLAAWFARVAERPGTVRAYARAKEINTAPTVDQQSRGVLFGQDASTVR

Sequences:

>Translated_232_residues
MIDLYYWTTPNGHKITMFLEEAGLPYRIVPVNIGRGEQFEPAFLRIAPNNRIPALVDHAPADGGAPLSIFESGAILLYLA
DKLGRFIPADLRGRNEALQWLFWQMGGLGPMAGQNHHFVQYAPEPLPYAIERYVKETSRLYGVLNKHLSDGRDYIAGEYS
IADMASYPWIVPHERQRQRLEDFPFLAAWFARVAERPGTVRAYARAKEINTAPTVDQQSRGVLFGQDASTVR
>Mature_232_residues
MIDLYYWTTPNGHKITMFLEEAGLPYRIVPVNIGRGEQFEPAFLRIAPNNRIPALVDHAPADGGAPLSIFESGAILLYLA
DKLGRFIPADLRGRNEALQWLFWQMGGLGPMAGQNHHFVQYAPEPLPYAIERYVKETSRLYGVLNKHLSDGRDYIAGEYS
IADMASYPWIVPHERQRQRLEDFPFLAAWFARVAERPGTVRAYARAKEINTAPTVDQQSRGVLFGQDASTVR

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=208, Percent_Identity=59.6153846153846, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI87082195, Length=214, Percent_Identity=39.2523364485981, Blast_Score=149, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324100, Length=234, Percent_Identity=31.1965811965812, Blast_Score=111, Evalue=8e-26,
Organism=Drosophila melanogaster, GI28571670, Length=192, Percent_Identity=28.125, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI17864596, Length=212, Percent_Identity=27.8301886792453, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 26217; Mature: 26217

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYYWTTPNGHKITMFLEEAGLPYRIVPVNIGRGEQFEPAFLRIAPNNRIPALVDHAP
CEEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCEEEECCC
ADGGAPLSIFESGAILLYLADKLGRFIPADLRGRNEALQWLFWQMGGLGPMAGQNHHFVQ
CCCCCCEEEECCCEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEE
YAPEPLPYAIERYVKETSRLYGVLNKHLSDGRDYIAGEYSIADMASYPWIVPHERQRQRL
ECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHCCCCEECCCHHHHHHH
EDFPFLAAWFARVAERPGTVRAYARAKEINTAPTVDQQSRGVLFGQDASTVR
HCCCHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MIDLYYWTTPNGHKITMFLEEAGLPYRIVPVNIGRGEQFEPAFLRIAPNNRIPALVDHAP
CEEEEEEECCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCEEEEECCCCCCCEEEECCC
ADGGAPLSIFESGAILLYLADKLGRFIPADLRGRNEALQWLFWQMGGLGPMAGQNHHFVQ
CCCCCCEEEECCCEEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEE
YAPEPLPYAIERYVKETSRLYGVLNKHLSDGRDYIAGEYSIADMASYPWIVPHERQRQRL
ECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHCCCCEECCCHHHHHHH
EDFPFLAAWFARVAERPGTVRAYARAKEINTAPTVDQQSRGVLFGQDASTVR
HCCCHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]