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The map label for this gene is tas [H]

Identifier: 126452140

GI number: 126452140

Start: 1805743

End: 1806795

Strand: Direct

Name: tas [H]

Synonym: BURPS1106A_1849

Alternate gene names: 126452140

Gene position: 1805743-1806795 (Clockwise)

Preceding gene: 126455018

Following gene: 126453257

Centisome position: 45.27

GC content: 66.76

Gene sequence:

>1053_bases
ATGGAATACCGCACACTCGGCGATTCAGGCGTCAAAGTCAGCCTGATTGGTCTCGGCACGATGACCTGGGGCGAGCAAAA
CACCGAAAGCGACGCGCATGCGCAACTCGATTACGCGATCGACCAGGGCGTCACGCTGATCGACACCGCCGAGATGTATC
CGGTGCCGCCTAAGGCGCAAACGCAGGGCCGCACGGAAACGTATCTCGGCACGTGGCTCGCGAAGCACCCGGCGCTGCGC
GAGAAGCTGACGATCGCGACGAAGATCGCCGGCCCCGCGCGCCAGCCGCACAACCCGACGCACATTCGCGGCGCGGGCAA
CCAGTTCGACCGCAAGAACCTGACCGAGGCGCTCGACGGCAGCCTGGCGCGCCTGCGCACCGATTACGTCGACTTGTACC
AGCTGCATTGGCCGGATCGCAGCACGACGACGTTCGGCCGCCCCGCGTATCCGTGGATCGACGATCCGTACACGGTGCCG
ATCGAAGAGACGCTCGCCGTCCTCGGCGATTTCGTCAAGGCGGGCAAGGTGCGCCATGTCGGCGTATCGAACGAGACGCC
GTGGGGCGTCGCGCAATTCCTCCGCGCAGCCGAGAAGCTCGGCCTGCCGCGCATCGTCAGCATCCAGAATCCGTACAGCC
TGCTGAACCGCACGTTCGAGAACGGCTTGTCGGAGTTCAGCCACCGCGAGCGCATCGGGCTGCTCGCGTATTCGCCGCTC
GCGTTCGGCTGGCTGTCGGGCAAGTACGAAGGCGGCGCGCGCCCCGAGGGCGCGCGCATCACGCGGTTCGAGCGCTTCCA
GCGCTACAGCAAGCCGCACGCGGTGCAGGCGACGTCGCGCTACGTCGCGCTCGCGAAGCGGCATGGATTGTCGCCCGCCC
AGCTCGCGCTCGCGTTCGTCAACAGTCGGCCGTTCGTGACGAGCAACCTGATCGGCGCGACGTCGCTCGCGCAATTGCGT
GAAAACGTCGCCAGCGTCGACGTGAAGCTCGCGCCCGAGATCCTCGCCGAGATCGACGCGCTCCACGAACAGCAGCCAAA
CCCCGCGCCGTAG

Upstream 100 bases:

>100_bases
CGAGCGCTGCGCCGGCAGCGGCTGCGCGGCAAGGCTCTGAAGCAATCGTTTCGATGTGTTAGCTTCGGATCTTTGCCTCC
GAAGCGACAGGAGCTTCAGC

Downstream 100 bases:

>100_bases
CGGCATCGGCGATCGGGCGGGCGCCGGCTGGGCGGCGCTCGGCGATGGCGCGCCGCCGCGGCCCGCCGCCTTGCCGGCCC
TCCGGATGCGCGGCCGGGCG

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MEYRTLGDSGVKVSLIGLGTMTWGEQNTESDAHAQLDYAIDQGVTLIDTAEMYPVPPKAQTQGRTETYLGTWLAKHPALR
EKLTIATKIAGPARQPHNPTHIRGAGNQFDRKNLTEALDGSLARLRTDYVDLYQLHWPDRSTTTFGRPAYPWIDDPYTVP
IEETLAVLGDFVKAGKVRHVGVSNETPWGVAQFLRAAEKLGLPRIVSIQNPYSLLNRTFENGLSEFSHRERIGLLAYSPL
AFGWLSGKYEGGARPEGARITRFERFQRYSKPHAVQATSRYVALAKRHGLSPAQLALAFVNSRPFVTSNLIGATSLAQLR
ENVASVDVKLAPEILAEIDALHEQQPNPAP

Sequences:

>Translated_350_residues
MEYRTLGDSGVKVSLIGLGTMTWGEQNTESDAHAQLDYAIDQGVTLIDTAEMYPVPPKAQTQGRTETYLGTWLAKHPALR
EKLTIATKIAGPARQPHNPTHIRGAGNQFDRKNLTEALDGSLARLRTDYVDLYQLHWPDRSTTTFGRPAYPWIDDPYTVP
IEETLAVLGDFVKAGKVRHVGVSNETPWGVAQFLRAAEKLGLPRIVSIQNPYSLLNRTFENGLSEFSHRERIGLLAYSPL
AFGWLSGKYEGGARPEGARITRFERFQRYSKPHAVQATSRYVALAKRHGLSPAQLALAFVNSRPFVTSNLIGATSLAQLR
ENVASVDVKLAPEILAEIDALHEQQPNPAP
>Mature_350_residues
MEYRTLGDSGVKVSLIGLGTMTWGEQNTESDAHAQLDYAIDQGVTLIDTAEMYPVPPKAQTQGRTETYLGTWLAKHPALR
EKLTIATKIAGPARQPHNPTHIRGAGNQFDRKNLTEALDGSLARLRTDYVDLYQLHWPDRSTTTFGRPAYPWIDDPYTVP
IEETLAVLGDFVKAGKVRHVGVSNETPWGVAQFLRAAEKLGLPRIVSIQNPYSLLNRTFENGLSEFSHRERIGLLAYSPL
AFGWLSGKYEGGARPEGARITRFERFQRYSKPHAVQATSRYVALAKRHGLSPAQLALAFVNSRPFVTSNLIGATSLAQLR
ENVASVDVKLAPEILAEIDALHEQQPNPAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=363, Percent_Identity=31.129476584022, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI4504825, Length=361, Percent_Identity=31.0249307479224, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI27436964, Length=360, Percent_Identity=30.2777777777778, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI27436962, Length=360, Percent_Identity=30.2777777777778, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI27436966, Length=360, Percent_Identity=30, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI27436971, Length=362, Percent_Identity=30.6629834254144, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI223718702, Length=326, Percent_Identity=26.6871165644172, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI41327764, Length=336, Percent_Identity=26.7857142857143, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI41152114, Length=336, Percent_Identity=26.7857142857143, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1789199, Length=350, Percent_Identity=56, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI87081735, Length=360, Percent_Identity=29.1666666666667, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1789375, Length=348, Percent_Identity=31.8965517241379, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1788070, Length=340, Percent_Identity=29.4117647058824, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788081, Length=356, Percent_Identity=28.6516853932584, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325169, Length=363, Percent_Identity=26.9972451790634, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323998, Length=343, Percent_Identity=24.198250728863, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319958, Length=321, Percent_Identity=24.6105919003115, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=269, Percent_Identity=24.5353159851301, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6319951, Length=344, Percent_Identity=22.3837209302326, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324694, Length=248, Percent_Identity=28.2258064516129, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646159, Length=252, Percent_Identity=31.3492063492063, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646155, Length=335, Percent_Identity=28.0597014925373, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38720; Mature: 38720

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRTLGDSGVKVSLIGLGTMTWGEQNTESDAHAQLDYAIDQGVTLIDTAEMYPVPPKAQ
CCCCCCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCC
TQGRTETYLGTWLAKHPALREKLTIATKIAGPARQPHNPTHIRGAGNQFDRKNLTEALDG
CCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCHHHHHHHHCC
SLARLRTDYVDLYQLHWPDRSTTTFGRPAYPWIDDPYTVPIEETLAVLGDFVKAGKVRHV
HHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCEEEE
GVSNETPWGVAQFLRAAEKLGLPRIVSIQNPYSLLNRTFENGLSEFSHRERIGLLAYSPL
CCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCEEEECCH
AFGWLSGKYEGGARPEGARITRFERFQRYSKPHAVQATSRYVALAKRHGLSPAQLALAFV
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
NSRPFVTSNLIGATSLAQLRENVASVDVKLAPEILAEIDALHEQQPNPAP
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEYRTLGDSGVKVSLIGLGTMTWGEQNTESDAHAQLDYAIDQGVTLIDTAEMYPVPPKAQ
CCCCCCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCC
TQGRTETYLGTWLAKHPALREKLTIATKIAGPARQPHNPTHIRGAGNQFDRKNLTEALDG
CCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCHHHHHHHHCC
SLARLRTDYVDLYQLHWPDRSTTTFGRPAYPWIDDPYTVPIEETLAVLGDFVKAGKVRHV
HHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCEEEE
GVSNETPWGVAQFLRAAEKLGLPRIVSIQNPYSLLNRTFENGLSEFSHRERIGLLAYSPL
CCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCEEEECCH
AFGWLSGKYEGGARPEGARITRFERFQRYSKPHAVQATSRYVALAKRHGLSPAQLALAFV
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
NSRPFVTSNLIGATSLAQLRENVASVDVKLAPEILAEIDALHEQQPNPAP
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]