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The map label for this gene is ppnK [H]

Identifier: 126452026

GI number: 126452026

Start: 3235202

End: 3236239

Strand: Direct

Name: ppnK [H]

Synonym: BURPS1106A_3318

Alternate gene names: 126452026

Gene position: 3235202-3236239 (Clockwise)

Preceding gene: 126453498

Following gene: 126455415

Centisome position: 81.11

GC content: 67.73

Gene sequence:

>1038_bases
ATGATGGAAAATTTTAGCGCAACCGGGCGGCGCCCGCGAGCGCCGCTTGCGCGCCTCGCCGCCCCCGCGCCCGTTTTGCC
GGCCGGCCGCCGGCGGGCGGTTCTTTTCGTCATCGAGCTATGGTGTAATGCCGGCATGAAAATCGGCCACCAATTCCATA
CCGTCGCGCTCGTCGGGCGCAGCAACACGCCCGGCATCGCCGAGCCGCTCGCGTCGCTCGCCGCGTGCATCGCGAAGCGC
GGCTTCGAAGTCGTGTTCGAGGCGGATACCGCGCAGGCGATCGGCAGCGCCGGCTACCCGGCGCTCACGCCCGCCGAGAT
CGGCGCGCGCGCCGACGTCGCGGTCGTGCTGGGCGGCGACGGCACGATGCTCGGCATGGGCCGCCAGCTCGCGCCGTACA
AGACGCCGCTCATCGGCATCAACCACGGCCGGCTCGGCTTCATCACCGATATCCCGGCGTCCGACATGCGCGAAGTCGTG
CCGATGATGCTCGCGGGCAGCTACGAGCGCGAGGAGCGCACGCTGCTCGAGGCGCGGATCGTGCGCAACGGCGAGCCGAT
CTATCACGCGCTCGCATTCAACGACGTCGTCGTGAACCGCAGCGGCTTCTCCGGGATGGCCGAGCTGCGCGTGTCGGTCG
ACGGCCGCTTCATGTACAACCAGCGCTCGGACGGCCTGATCGTCGCGACGCCGACGGGCTCGACCGCGTACGCGCTATCC
TCGCAGGGGCCGATCCTGCATCCGCAACTGCAAGGCATCGTGCTCGTGCCGATCGCGCCGCACGCGCTGTCGAACCGGCC
GATCGTGCTGCCGGACGATTCGAAGATCGCGATCCAGATCATCGGCGGGCGCGACGTGAACGTGAACTTCGACATGCAGT
CGTTCACCGCGCTCGAGCTGAACGACACGATCGAGGTGCGCCGCTCGAAGCACACGGTGCCGTTCCTGCACCCGGTCGGC
TACAGCTATTACGCGACGCTGCGCAAGAAGCTGCACTGGAACGAACATCCGTCGAGCGAAGAAGACGACGACGCATAA

Upstream 100 bases:

>100_bases
CCCGGAATAACGAGACAACGTGCGCGATCCGACCGGCTGACCGTCGGCGATATACCGCTCGATCAGTGTCTTGAGGAGGG
TTCGTGCGCGTGGATCTAAC

Downstream 100 bases:

>100_bases
GTCCTCACGCCATCCTCCGACCGACATCCATGCTCCGCCACCTCTCGATCCGCGATTTCGTCATCGTCGCCGCGCTCGAT
CTCGAATTCGACAGCGGCTT

Product: NAD(+)/NADH kinase family protein

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MMENFSATGRRPRAPLARLAAPAPVLPAGRRRAVLFVIELWCNAGMKIGHQFHTVALVGRSNTPGIAEPLASLAACIAKR
GFEVVFEADTAQAIGSAGYPALTPAEIGARADVAVVLGGDGTMLGMGRQLAPYKTPLIGINHGRLGFITDIPASDMREVV
PMMLAGSYEREERTLLEARIVRNGEPIYHALAFNDVVVNRSGFSGMAELRVSVDGRFMYNQRSDGLIVATPTGSTAYALS
SQGPILHPQLQGIVLVPIAPHALSNRPIVLPDDSKIAIQIIGGRDVNVNFDMQSFTALELNDTIEVRRSKHTVPFLHPVG
YSYYATLRKKLHWNEHPSSEEDDDA

Sequences:

>Translated_345_residues
MMENFSATGRRPRAPLARLAAPAPVLPAGRRRAVLFVIELWCNAGMKIGHQFHTVALVGRSNTPGIAEPLASLAACIAKR
GFEVVFEADTAQAIGSAGYPALTPAEIGARADVAVVLGGDGTMLGMGRQLAPYKTPLIGINHGRLGFITDIPASDMREVV
PMMLAGSYEREERTLLEARIVRNGEPIYHALAFNDVVVNRSGFSGMAELRVSVDGRFMYNQRSDGLIVATPTGSTAYALS
SQGPILHPQLQGIVLVPIAPHALSNRPIVLPDDSKIAIQIIGGRDVNVNFDMQSFTALELNDTIEVRRSKHTVPFLHPVG
YSYYATLRKKLHWNEHPSSEEDDDA
>Mature_345_residues
MMENFSATGRRPRAPLARLAAPAPVLPAGRRRAVLFVIELWCNAGMKIGHQFHTVALVGRSNTPGIAEPLASLAACIAKR
GFEVVFEADTAQAIGSAGYPALTPAEIGARADVAVVLGGDGTMLGMGRQLAPYKTPLIGINHGRLGFITDIPASDMREVV
PMMLAGSYEREERTLLEARIVRNGEPIYHALAFNDVVVNRSGFSGMAELRVSVDGRFMYNQRSDGLIVATPTGSTAYALS
SQGPILHPQLQGIVLVPIAPHALSNRPIVLPDDSKIAIQIIGGRDVNVNFDMQSFTALELNDTIEVRRSKHTVPFLHPVG
YSYYATLRKKLHWNEHPSSEEDDDA

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=260, Percent_Identity=28.0769230769231, Blast_Score=95, Evalue=9e-20,
Organism=Escherichia coli, GI1788968, Length=289, Percent_Identity=38.4083044982699, Blast_Score=205, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6320794, Length=241, Percent_Identity=29.4605809128631, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6322509, Length=242, Percent_Identity=30.9917355371901, Blast_Score=116, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6325068, Length=182, Percent_Identity=34.6153846153846, Blast_Score=106, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28573828, Length=251, Percent_Identity=30.6772908366534, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI161077047, Length=251, Percent_Identity=30.6772908366534, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28573832, Length=251, Percent_Identity=30.6772908366534, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573830, Length=251, Percent_Identity=30.6772908366534, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573826, Length=251, Percent_Identity=30.6772908366534, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20129957, Length=276, Percent_Identity=28.6231884057971, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI281363321, Length=276, Percent_Identity=28.6231884057971, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI281363323, Length=276, Percent_Identity=28.6231884057971, Blast_Score=95, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24653422, Length=276, Percent_Identity=28.6231884057971, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24653424, Length=276, Percent_Identity=28.6231884057971, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 37325; Mature: 37325

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMENFSATGRRPRAPLARLAAPAPVLPAGRRRAVLFVIELWCNAGMKIGHQFHTVALVGR
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEEEEEEEHHCCCCCCCCEEEEEEEEEC
SNTPGIAEPLASLAACIAKRGFEVVFEADTAQAIGSAGYPALTPAEIGARADVAVVLGGD
CCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCCCCHHHCCCCCCEEEEECCC
GTMLGMGRQLAPYKTPLIGINHGRLGFITDIPASDMREVVPMMLAGSYEREERTLLEARI
CEEEECCCCCCCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VRNGEPIYHALAFNDVVVNRSGFSGMAELRVSVDGRFMYNQRSDGLIVATPTGSTAYALS
HCCCCCEEEEEEECEEEEECCCCCCEEEEEEEECCEEEECCCCCCEEEECCCCCEEEEEC
SQGPILHPQLQGIVLVPIAPHALSNRPIVLPDDSKIAIQIIGGRDVNVNFDMQSFTALEL
CCCCEECCCCCCEEEEEECCHHCCCCCEEECCCCEEEEEEECCEEEEEEECCCCEEEEEE
NDTIEVRRSKHTVPFLHPVGYSYYATLRKKLHWNEHPSSEEDDDA
CCCEEEHHCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MMENFSATGRRPRAPLARLAAPAPVLPAGRRRAVLFVIELWCNAGMKIGHQFHTVALVGR
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEEEEEEEHHCCCCCCCCEEEEEEEEEC
SNTPGIAEPLASLAACIAKRGFEVVFEADTAQAIGSAGYPALTPAEIGARADVAVVLGGD
CCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHCCCCCCCCCHHHCCCCCCEEEEECCC
GTMLGMGRQLAPYKTPLIGINHGRLGFITDIPASDMREVVPMMLAGSYEREERTLLEARI
CEEEECCCCCCCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VRNGEPIYHALAFNDVVVNRSGFSGMAELRVSVDGRFMYNQRSDGLIVATPTGSTAYALS
HCCCCCEEEEEEECEEEEECCCCCCEEEEEEEECCEEEECCCCCCEEEECCCCCEEEEEC
SQGPILHPQLQGIVLVPIAPHALSNRPIVLPDDSKIAIQIIGGRDVNVNFDMQSFTALEL
CCCCEECCCCCCEEEEEECCHHCCCCCEEECCCCEEEEEEECCEEEEEEECCCCEEEEEE
NDTIEVRRSKHTVPFLHPVGYSYYATLRKKLHWNEHPSSEEDDDA
CCCEEEHHCCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA