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The map label for this gene is hoxN [H]

Identifier: 126451877

GI number: 126451877

Start: 1917780

End: 1918841

Strand: Direct

Name: hoxN [H]

Synonym: BURPS1106A_1952

Alternate gene names: 126451877

Gene position: 1917780-1918841 (Clockwise)

Preceding gene: 126452199

Following gene: 126451969

Centisome position: 48.08

GC content: 66.1

Gene sequence:

>1062_bases
ATGCTCGAATCGTTTCTTCGTCTCTTCAACGACAGCCCCGCCGAGCTGCGCAGCAAGATCGTCGGGATCTACGCGATGCT
GATCGCGTTCAACGTCGGCGCGTGGGCCTGGGCGTTCGCCGCGTTCCACGGCCAGCCGGTGCTGCTCGGCACCGCGCTCC
TCGCGTATACGTTCGGGCTGCGCCATGCGGTCGACGCCGATCACATCGCCGCGATCGACAACGTCACGCGCAAGCTGATG
CACGAGAAGAAGAACCCGCTCGGCGCGGGGCTGTTCTTCTCGCTCGGGCATTCGAGCGTCGTGATCCTGATGACGGTGGC
CGTCGCGCTGACGGCCGCGACGCTCGCCGAGCGCTTCGAGGGCATGAAGGCATGGGGCGGCGCGATCGGCACGAGCGTGT
CGGCGTTCTTCCTGCTCGTGCTCGCGTTCGCGAACCTGCTGATCCTGATCTCCGTGTACCGGACGTTTCGCGCGGTGCGG
CGCGGCGAGCCGCTCGTCGAGCAGGATCTCGACATCCTGCTCAACCAGCGCGGCTTCTTCGCGCGGATCTTCCGGCCGCT
GTTCGCGATCGTGTCGCGCAGCTGGCACCTGTATCCGATCGGCTTCCTGTTCGGCCTCGGCTTCGACACCGCGACCGAGA
TCGCGCTGTTCGGCATCTCGGCGACGCAGGCGCACGGCGGGCTGTCGTTCTGGTCGGTGATGGCGTTGCCCGTGCTGTTC
ACCGCGGGCATGACGCTCGTCGACACCACCGACGGCATCATGATGATGGGCGCGTACCGCTGGGCATTCGTGCGGCCGAT
CCGCAAGATCTACTACAACATGACGATCACGTTCGTATCGGTGCTCGTCGCGATCGTGATCGGCGGCATCGAGGCGCTCG
CGCTGATCGGCGGCAAGCTCGCGCTCAAGGGCGGCGTGTGGGATTTCGCCGCGATGGCGGCCGAACACTTCGGCGTGCTC
GGCTACTTCGTGATCGGCCTGTTCGCCGCGAGCTGGATCGTCTCCGCGCTCATCTACCGGATCAGGCGCTACGACGACAT
CGACGTGACGCTCTCCGCGTGA

Upstream 100 bases:

>100_bases
CGAGCGATCGACGGGCGCGGCGGGGGAGCACGTGCATTGCACGCGATGCCGCGCGTGTTGGCATTCGTCTCGTTTGTCGA
CCGTTCGCAAAGGGAGCGCC

Downstream 100 bases:

>100_bases
GGCCCGCGCGGGGCGCTTCCCCATGAGCTCATGCGCCGCGCGCGTCGCACGCCGCCGCGGCACCGGCCCGAGGCCCGATT
ACCCCTTACTCCATGACCCG

Product: high-affinity nickel transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLESFLRLFNDSPAELRSKIVGIYAMLIAFNVGAWAWAFAAFHGQPVLLGTALLAYTFGLRHAVDADHIAAIDNVTRKLM
HEKKNPLGAGLFFSLGHSSVVILMTVAVALTAATLAERFEGMKAWGGAIGTSVSAFFLLVLAFANLLILISVYRTFRAVR
RGEPLVEQDLDILLNQRGFFARIFRPLFAIVSRSWHLYPIGFLFGLGFDTATEIALFGISATQAHGGLSFWSVMALPVLF
TAGMTLVDTTDGIMMMGAYRWAFVRPIRKIYYNMTITFVSVLVAIVIGGIEALALIGGKLALKGGVWDFAAMAAEHFGVL
GYFVIGLFAASWIVSALIYRIRRYDDIDVTLSA

Sequences:

>Translated_353_residues
MLESFLRLFNDSPAELRSKIVGIYAMLIAFNVGAWAWAFAAFHGQPVLLGTALLAYTFGLRHAVDADHIAAIDNVTRKLM
HEKKNPLGAGLFFSLGHSSVVILMTVAVALTAATLAERFEGMKAWGGAIGTSVSAFFLLVLAFANLLILISVYRTFRAVR
RGEPLVEQDLDILLNQRGFFARIFRPLFAIVSRSWHLYPIGFLFGLGFDTATEIALFGISATQAHGGLSFWSVMALPVLF
TAGMTLVDTTDGIMMMGAYRWAFVRPIRKIYYNMTITFVSVLVAIVIGGIEALALIGGKLALKGGVWDFAAMAAEHFGVL
GYFVIGLFAASWIVSALIYRIRRYDDIDVTLSA
>Mature_353_residues
MLESFLRLFNDSPAELRSKIVGIYAMLIAFNVGAWAWAFAAFHGQPVLLGTALLAYTFGLRHAVDADHIAAIDNVTRKLM
HEKKNPLGAGLFFSLGHSSVVILMTVAVALTAATLAERFEGMKAWGGAIGTSVSAFFLLVLAFANLLILISVYRTFRAVR
RGEPLVEQDLDILLNQRGFFARIFRPLFAIVSRSWHLYPIGFLFGLGFDTATEIALFGISATQAHGGLSFWSVMALPVLF
TAGMTLVDTTDGIMMMGAYRWAFVRPIRKIYYNMTITFVSVLVAIVIGGIEALALIGGKLALKGGVWDFAAMAAEHFGVL
GYFVIGLFAASWIVSALIYRIRRYDDIDVTLSA

Specific function: High-affinity nickel transporter responsible for nickel uptake. Necessary for high levels of activity of hydrogenase and urease [H]

COG id: COG3376

COG function: function code P; High-affinity nickel permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NiCoT transporter (TC 2.A.52) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004688
- InterPro:   IPR011541 [H]

Pfam domain/function: PF03824 NicO [H]

EC number: NA

Molecular weight: Translated: 38609; Mature: 38609

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLESFLRLFNDSPAELRSKIVGIYAMLIAFNVGAWAWAFAAFHGQPVLLGTALLAYTFGL
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RHAVDADHIAAIDNVTRKLMHEKKNPLGAGLFFSLGHSSVVILMTVAVALTAATLAERFE
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GMKAWGGAIGTSVSAFFLLVLAFANLLILISVYRTFRAVRRGEPLVEQDLDILLNQRGFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHH
ARIFRPLFAIVSRSWHLYPIGFLFGLGFDTATEIALFGISATQAHGGLSFWSVMALPVLF
HHHHHHHHHHHHCCCCEEEHHHHHHCCCCHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHH
TAGMTLVDTTDGIMMMGAYRWAFVRPIRKIYYNMTITFVSVLVAIVIGGIEALALIGGKL
HCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ALKGGVWDFAAMAAEHFGVLGYFVIGLFAASWIVSALIYRIRRYDDIDVTLSA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECC
>Mature Secondary Structure
MLESFLRLFNDSPAELRSKIVGIYAMLIAFNVGAWAWAFAAFHGQPVLLGTALLAYTFGL
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RHAVDADHIAAIDNVTRKLMHEKKNPLGAGLFFSLGHSSVVILMTVAVALTAATLAERFE
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GMKAWGGAIGTSVSAFFLLVLAFANLLILISVYRTFRAVRRGEPLVEQDLDILLNQRGFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHH
ARIFRPLFAIVSRSWHLYPIGFLFGLGFDTATEIALFGISATQAHGGLSFWSVMALPVLF
HHHHHHHHHHHHCCCCEEEHHHHHHCCCCHHHHHHHCCCCHHCCCCCHHHHHHHHHHHHH
TAGMTLVDTTDGIMMMGAYRWAFVRPIRKIYYNMTITFVSVLVAIVIGGIEALALIGGKL
HCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ALKGGVWDFAAMAAEHFGVLGYFVIGLFAASWIVSALIYRIRRYDDIDVTLSA
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1847142; 7896709; 12948488; 7934894 [H]