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The map label for this gene is gph [C]

Identifier: 126451876

GI number: 126451876

Start: 2899600

End: 2900325

Strand: Direct

Name: gph [C]

Synonym: BURPS1106A_2955

Alternate gene names: 126451876

Gene position: 2899600-2900325 (Clockwise)

Preceding gene: 126455387

Following gene: 126454643

Centisome position: 72.7

GC content: 73.14

Gene sequence:

>726_bases
ATGAGCCTTTCGTCGCCCTCCTTCGCCGCCCCGCTGTCCGACGCGCCGCGCCTCGACGCATGCGAGGCCGTGCTGTTCGA
TCTCGACGGCACGCTCGCCGACACCGCGCCCGATCTCGCCGCCGCGGTCAACAAGATGCAGCGCTCGCGCGGCATCGCAC
AAACGCCGCTCGACGCGCTGCGCCCGCTCGCGTCGGCGGGCGCGCGCGGCCTGATCGGCGGCGCGTTCGGCATCGCGCCC
GCGGACGCCGAATTCGACGCGCTGCGCGACGAATTCCTCGCGAACTACGCGGCGGATCTGTGCGTGCACACGACGCTCTT
TCCGGGCATCGGCGCGCTGCTCGACGACCTCGACGCGCGCGGCGTGCGCTGGGGCATCGTGACCAACAAGGCTGCGCGGT
TCACCGATCCGCTCGTTGCGCTGCTCGGCCTCGCGGCGCGCGCGGCGTGCGTGGTCAGCGGCGACACGGCATCGCACCCG
AAGCCGCATCCGGCGCCGCTGCTGTACGCGGCCGACCGCCTCTCGCTCGCCCCCGAGCGGATCGTGTACGTCGGCGACGA
CCTTCGCGACATCCAGGCGGGCAGCGCGGCCGGCATGCCGACGGTCGCCGCCGCGTACGGCTATTGCGGCGACGGCGCCG
CCCCCGCCGACTGGCGGGCGCAGCATCTCGTCGAGACGACGGACGACCTGCAGCGGCTGCTGCGCGTGTTGCGCTATAAT
GCTTGA

Upstream 100 bases:

>100_bases
CCGCTCGCGAAGCGCTTCGCGCTGTCGAACGACACCGACGTCAACTATCTCGTCGCGTGCCGCCGCGGCGCCTGACCCGC
CACTCGCTCCGATCGCATTC

Downstream 100 bases:

>100_bases
TCCGCTGGGGGCGACCTGGTTTCGACAGGGGTTGTGAAGCGGCTAGGGCATGTCGAGGACCCGTCACCTCGTTAATCAAT
GGGAAAAACGTAACTGCAAA

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSLSSPSFAAPLSDAPRLDACEAVLFDLDGTLADTAPDLAAAVNKMQRSRGIAQTPLDALRPLASAGARGLIGGAFGIAP
ADAEFDALRDEFLANYAADLCVHTTLFPGIGALLDDLDARGVRWGIVTNKAARFTDPLVALLGLAARAACVVSGDTASHP
KPHPAPLLYAADRLSLAPERIVYVGDDLRDIQAGSAAGMPTVAAAYGYCGDGAAPADWRAQHLVETTDDLQRLLRVLRYN
A

Sequences:

>Translated_241_residues
MSLSSPSFAAPLSDAPRLDACEAVLFDLDGTLADTAPDLAAAVNKMQRSRGIAQTPLDALRPLASAGARGLIGGAFGIAP
ADAEFDALRDEFLANYAADLCVHTTLFPGIGALLDDLDARGVRWGIVTNKAARFTDPLVALLGLAARAACVVSGDTASHP
KPHPAPLLYAADRLSLAPERIVYVGDDLRDIQAGSAAGMPTVAAAYGYCGDGAAPADWRAQHLVETTDDLQRLLRVLRYN
A
>Mature_240_residues
SLSSPSFAAPLSDAPRLDACEAVLFDLDGTLADTAPDLAAAVNKMQRSRGIAQTPLDALRPLASAGARGLIGGAFGIAPA
DAEFDALRDEFLANYAADLCVHTTLFPGIGALLDDLDARGVRWGIVTNKAARFTDPLVALLGLAARAACVVSGDTASHPK
PHPAPLLYAADRLSLAPERIVYVGDDLRDIQAGSAAGMPTVAAAYGYCGDGAAPADWRAQHLVETTDDLQRLLRVLRYNA

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=212, Percent_Identity=34.9056603773585, Blast_Score=111, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 25121; Mature: 24989

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSSPSFAAPLSDAPRLDACEAVLFDLDGTLADTAPDLAAAVNKMQRSRGIAQTPLDAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCCHHHH
RPLASAGARGLIGGAFGIAPADAEFDALRDEFLANYAADLCVHTTLFPGIGALLDDLDAR
HHHHHCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVRWGIVTNKAARFTDPLVALLGLAARAACVVSGDTASHPKPHPAPLLYAADRLSLAPER
CEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEHHHHHCCCCE
IVYVGDDLRDIQAGSAAGMPTVAAAYGYCGDGAAPADWRAQHLVETTDDLQRLLRVLRYN
EEEECCCHHHHCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
A
C
>Mature Secondary Structure 
SLSSPSFAAPLSDAPRLDACEAVLFDLDGTLADTAPDLAAAVNKMQRSRGIAQTPLDAL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHCCCCCCCHHHH
RPLASAGARGLIGGAFGIAPADAEFDALRDEFLANYAADLCVHTTLFPGIGALLDDLDAR
HHHHHCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GVRWGIVTNKAARFTDPLVALLGLAARAACVVSGDTASHPKPHPAPLLYAADRLSLAPER
CEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEHHHHHCCCCE
IVYVGDDLRDIQAGSAAGMPTVAAAYGYCGDGAAPADWRAQHLVETTDDLQRLLRVLRYN
EEEECCCHHHHCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA