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The map label for this gene is hflX [H]

Identifier: 126451860

GI number: 126451860

Start: 2210341

End: 2211504

Strand: Reverse

Name: hflX [H]

Synonym: BURPS1106A_2221

Alternate gene names: 126451860

Gene position: 2211504-2210341 (Counterclockwise)

Preceding gene: 126452708

Following gene: 126451985

Centisome position: 55.45

GC content: 66.24

Gene sequence:

>1164_bases
TTGATCAACGCAGCGTTAGTCGGCATCGATTTCGGCAAGACCGATTTCGAAGCCAGTCTCGAAGAACTCAGCCTGCTCGC
CTCCAGCGCGGGCGCCCATCCCGCCGTCACGCTGACGGGCCGCCGCTCCAGCCCCGACGCCGCCTTGTTCGTCGGCAGCG
GCAAAGCCGACGAACTGCGGCTTGCCTGCGAAGCGAACGACGTCGAAATCGTCATCTTCAATCACGCGCTCGCACCCGCC
CAGCAACGCAATCTGGAGCGAGTGCTTAATCGGCGCGTCATCGATCGTACGAGCCTCATTCTCGACATCTTCGCGCAGCG
CGCGCGCAGCCACGAAGGCAAGCTGCAGGTCGAGCTCGCGCAGCTGCAGTACCTCGCGACCCGCCTGATTCGGGCCTGGA
CCCACCTCGAGCGGCAAAAGGGTGGCATCGGCTTGCGCGGCCCCGGCGAGACGCAGCTCGAAACCGACCGCCGGCTGATC
GGCGAGCGCATCAAGATGCTGAAATCGCGGCTCGACAAGCTGCGCCGCCAGCATCACACGCAGCGCCGGCAGCGCGCGCG
CAGCGGCACGCTGTCGGTGTCGCTCGTCGGCTATACGAACGCGGGCAAGTCGACGCTGTTCAATGCGCTGACGAAAGCGC
AGGCGTATGCGGCCGACCAGCTGTTCGCGACGCTCGACACGACGTCGCGGCGCGTGTATCTCGGCGACGAGGTCGGGCAG
ATCGTCGTGTCCGATACCGTCGGCTTCATTCGCGAGTTGCCGCACCAGCTCGTCGCGGCGTTCCGCGCGACGCTCGAGGA
GACGATTCACGCGGATCTGCTGCTGCATGTGGTCGATGCGTCGAGCGCGGTGCGGCTCGAGCAGATCGACCAAGTGAACG
ACGTGCTGCGCGAAATCGGGGCGGATTCGATCCGCCAGATTCTCGTGTTCAACAAGATCGACGCGGTGCCCGAGCTCGCG
GCCCGCGGCGGCGCGGTCGAGCGGGACGAGTATGGTAATATTTCGCGCGTCTTTTTGAGCGCGCGCACGGGCCAGGGTCT
GGATTCGCTGCGTGCCGCCATCGCCGAGATCGCTACCGCGGAACATCTTGTCGGCGCCGCGCCGCTCGACGGCGCGCCGG
CGCTACCACACGAAGACCACCCGGTTTCCGAACACGGGCGCTGA

Upstream 100 bases:

>100_bases
TCCACCCGGATGCGGAAGCAGCGTCCTAACCCATTGCCGCGGCTGGCTTGCGTCGCCGTCGGCAGCCGATGCCAGCCGCC
TTATCTTGACCTCCGATAAT

Downstream 100 bases:

>100_bases
CGGCTGCGGCCGATCAAGTTGCGCCAATCTGGTGAACAAACACAGGTGAACGACTACAACGAGCGGAGTACCTGGCGGCG
AATGCGCGCCTTGCTGTCGA

Product: GTP-binding proten HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MINAALVGIDFGKTDFEASLEELSLLASSAGAHPAVTLTGRRSSPDAALFVGSGKADELRLACEANDVEIVIFNHALAPA
QQRNLERVLNRRVIDRTSLILDIFAQRARSHEGKLQVELAQLQYLATRLIRAWTHLERQKGGIGLRGPGETQLETDRRLI
GERIKMLKSRLDKLRRQHHTQRRQRARSGTLSVSLVGYTNAGKSTLFNALTKAQAYAADQLFATLDTTSRRVYLGDEVGQ
IVVSDTVGFIRELPHQLVAAFRATLEETIHADLLLHVVDASSAVRLEQIDQVNDVLREIGADSIRQILVFNKIDAVPELA
ARGGAVERDEYGNISRVFLSARTGQGLDSLRAAIAEIATAEHLVGAAPLDGAPALPHEDHPVSEHGR

Sequences:

>Translated_387_residues
MINAALVGIDFGKTDFEASLEELSLLASSAGAHPAVTLTGRRSSPDAALFVGSGKADELRLACEANDVEIVIFNHALAPA
QQRNLERVLNRRVIDRTSLILDIFAQRARSHEGKLQVELAQLQYLATRLIRAWTHLERQKGGIGLRGPGETQLETDRRLI
GERIKMLKSRLDKLRRQHHTQRRQRARSGTLSVSLVGYTNAGKSTLFNALTKAQAYAADQLFATLDTTSRRVYLGDEVGQ
IVVSDTVGFIRELPHQLVAAFRATLEETIHADLLLHVVDASSAVRLEQIDQVNDVLREIGADSIRQILVFNKIDAVPELA
ARGGAVERDEYGNISRVFLSARTGQGLDSLRAAIAEIATAEHLVGAAPLDGAPALPHEDHPVSEHGR
>Mature_387_residues
MINAALVGIDFGKTDFEASLEELSLLASSAGAHPAVTLTGRRSSPDAALFVGSGKADELRLACEANDVEIVIFNHALAPA
QQRNLERVLNRRVIDRTSLILDIFAQRARSHEGKLQVELAQLQYLATRLIRAWTHLERQKGGIGLRGPGETQLETDRRLI
GERIKMLKSRLDKLRRQHHTQRRQRARSGTLSVSLVGYTNAGKSTLFNALTKAQAYAADQLFATLDTTSRRVYLGDEVGQ
IVVSDTVGFIRELPHQLVAAFRATLEETIHADLLLHVVDASSAVRLEQIDQVNDVLREIGADSIRQILVFNKIDAVPELA
ARGGAVERDEYGNISRVFLSARTGQGLDSLRAAIAEIATAEHLVGAAPLDGAPALPHEDHPVSEHGR

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=233, Percent_Identity=37.3390557939914, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI310133116, Length=230, Percent_Identity=37.8260869565217, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI310124269, Length=212, Percent_Identity=38.6792452830189, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI310124267, Length=212, Percent_Identity=38.6792452830189, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI310124171, Length=212, Percent_Identity=38.6792452830189, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI310124169, Length=212, Percent_Identity=38.6792452830189, Blast_Score=119, Evalue=7e-27,
Organism=Escherichia coli, GI1790615, Length=372, Percent_Identity=55.6451612903226, Blast_Score=383, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17561038, Length=290, Percent_Identity=31.7241379310345, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24650079, Length=317, Percent_Identity=33.1230283911672, Blast_Score=108, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 42317; Mature: 42317

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINAALVGIDFGKTDFEASLEELSLLASSAGAHPAVTLTGRRSSPDAALFVGSGKADELR
CCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCCCCEE
LACEANDVEIVIFNHALAPAQQRNLERVLNRRVIDRTSLILDIFAQRARSHEGKLQVELA
EEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHH
QLQYLATRLIRAWTHLERQKGGIGLRGPGETQLETDRRLIGERIKMLKSRLDKLRRQHHT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRQRARSGTLSVSLVGYTNAGKSTLFNALTKAQAYAADQLFATLDTTSRRVYLGDEVGQ
HHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
IVVSDTVGFIRELPHQLVAAFRATLEETIHADLLLHVVDASSAVRLEQIDQVNDVLREIG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
ADSIRQILVFNKIDAVPELAARGGAVERDEYGNISRVFLSARTGQGLDSLRAAIAEIATA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEECCCCCCHHHHHHHHHHHHHH
EHLVGAAPLDGAPALPHEDHPVSEHGR
HHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MINAALVGIDFGKTDFEASLEELSLLASSAGAHPAVTLTGRRSSPDAALFVGSGKADELR
CCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEECCCCCCEE
LACEANDVEIVIFNHALAPAQQRNLERVLNRRVIDRTSLILDIFAQRARSHEGKLQVELA
EEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHH
QLQYLATRLIRAWTHLERQKGGIGLRGPGETQLETDRRLIGERIKMLKSRLDKLRRQHHT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRQRARSGTLSVSLVGYTNAGKSTLFNALTKAQAYAADQLFATLDTTSRRVYLGDEVGQ
HHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
IVVSDTVGFIRELPHQLVAAFRATLEETIHADLLLHVVDASSAVRLEQIDQVNDVLREIG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHC
ADSIRQILVFNKIDAVPELAARGGAVERDEYGNISRVFLSARTGQGLDSLRAAIAEIATA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEEECCCCCCHHHHHHHHHHHHHH
EHLVGAAPLDGAPALPHEDHPVSEHGR
HHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]