Click here to switch to the map view.

The map label for this gene is pntB [H]

Identifier: 126451767

GI number: 126451767

Start: 3302080

End: 3303534

Strand: Reverse

Name: pntB [H]

Synonym: BURPS1106A_3384

Alternate gene names: 126451767

Gene position: 3303534-3302080 (Counterclockwise)

Preceding gene: 126452789

Following gene: 126453976

Centisome position: 82.83

GC content: 65.29

Gene sequence:

>1455_bases
ATGAGCATGAACGTCGTCACGCTGCTGTATCTCGTTGCGTCGGTGTGCTTCATCCAGGCGCTGAAGGGGCTGTCGAACCC
GAAGAGCGCTAGACGAGGCAATCTATTCGGCATGGTCGGCATGGCGATCGCGATCCTCACGACCGTCGCGCTGATCGCGA
AGCAGGCCGCGTGGCTCGGCGCGAACCTGCCGCTCGGCCTCGCGCTCGTGTTCGGCGCGCTCGTGATCGGCGGCGCGGTG
GGGGCGGTGATCGCCGCGCGCGTCGAGATGACGAAGATGCCGGAGCTCGTCGCGGCGATGCACTCGCTGATCGGCCTCGC
GGCCGTGTGCATCGCGATCGCGGTGGTCGCGGAGCCGGAGGCGTTCGGGCTCGTGCCGCAGGATGCGAGCGCGCCGAACT
TCATTCCGTACGGCAACCGGATCGAGCTGTTCATCGGCACGTTCGTCGGCGCGATCACGTTCTCGGGCTCGGTGATCGCG
TTCGGCAAGCTGTCGGGCAAGTACAGGTTCCGGCTGTTCCAGGGCGCGCCCGTCGTCTATCCGGGCCAGCATCTGATCAA
CCTGATGCTCGCGCTCGCGATGCTCGGCTTCGGCATCCTGTTCTTCATCACGCAATCGTGGCTGCCGTTCGGGATCATGA
CGGCGATCGCGTTCGCGCTCGGCGTGCTGATCATCATTCCGATCGGCGGCGCGGACATGCCGGTCGTCGTGTCGATGCTG
AACTCGTACTCGGGATGGGCGGCGGCGGGCATCGGCTTTTCGCTGAACAACGCGATGCTGATCATCGCCGGCTCGCTCGT
CGGCTCGTCGGGCGCGATCCTGTCGTACATCATGTGCCACGCGATGAACCGCTCGTTCTTCAACGTGATCCTCGGCGGCT
TCGGCGGCGACGCGGCCGCGGCGACGGCGGGCGGCGCGAAGGAGCAGCGGCCGGTGAAGTCGGGCTCGGCGGAGGATGCG
TCGTTCATGCTCGGCAATGCGGAGACGGTCGTGATCGTGCCGGGCTACGGGCTGGCGGTGGCGCGCGCGCAGCACGCGCT
CAAGGAGCTGACCGACAAGCTCGTCGAGAAGGGGATCGACGTGAAGTACGCGATTCACCCGGTCGCGGGACGGATGCCGG
GACACATGAACGTGCTGCTCGCGGAAGCCGAGGTGCCGTACGAGATCGTTCACGAGATGGAGGACATCAACGGCGAGTTC
GGGCAGGTGGACGTGGTGCTCGTGCTCGGGGCGAACGACGTGGTGAATCCGGCGGCGAAGAACGATCCGAAATCGCCGAT
CGCGGGGATGCCGATCATCGAGGCGTACAAGGCGCGCACGGTGATCGTCAACAAGCGGTCGATGGCGGCGGGTTATGCGG
GCCTCGACAACGAACTTTTCTACATGGACAAGACGATGATGGTCTTCGGCGATGCGAAGAAGGTCATCGAGGATATGGTG
AAGTCGGTCGAGTGA

Upstream 100 bases:

>100_bases
TCAACGTGTTCGGCGGCTTCCTCGTCACGCGGCGCATGCTCGAGATGTTCAAGAAGAAGGAGCCCAGGCAGAAAGCCGAC
CACGCGAAGGAGGGCGCGCG

Downstream 100 bases:

>100_bases
CGCGGCGGCACGCCCGGCCGGCGGCCGGGCGTTCGATGCATCGCGGGGCGGGTATCGCGGCGAGCGGGACGCGCGTGGCG
GGTCGTGCGTGGTGGGGGCG

Product: NAD(P) transhydrogenase, beta subunit

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTVALIAKQAAWLGANLPLGLALVFGALVIGGAV
GAVIAARVEMTKMPELVAAMHSLIGLAAVCIAIAVVAEPEAFGLVPQDASAPNFIPYGNRIELFIGTFVGAITFSGSVIA
FGKLSGKYRFRLFQGAPVVYPGQHLINLMLALAMLGFGILFFITQSWLPFGIMTAIAFALGVLIIIPIGGADMPVVVSML
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGDAAAATAGGAKEQRPVKSGSAEDA
SFMLGNAETVVIVPGYGLAVARAQHALKELTDKLVEKGIDVKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEF
GQVDVVLVLGANDVVNPAAKNDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMV
KSVE

Sequences:

>Translated_484_residues
MSMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTVALIAKQAAWLGANLPLGLALVFGALVIGGAV
GAVIAARVEMTKMPELVAAMHSLIGLAAVCIAIAVVAEPEAFGLVPQDASAPNFIPYGNRIELFIGTFVGAITFSGSVIA
FGKLSGKYRFRLFQGAPVVYPGQHLINLMLALAMLGFGILFFITQSWLPFGIMTAIAFALGVLIIIPIGGADMPVVVSML
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGDAAAATAGGAKEQRPVKSGSAEDA
SFMLGNAETVVIVPGYGLAVARAQHALKELTDKLVEKGIDVKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEF
GQVDVVLVLGANDVVNPAAKNDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMV
KSVE
>Mature_483_residues
SMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTVALIAKQAAWLGANLPLGLALVFGALVIGGAVG
AVIAARVEMTKMPELVAAMHSLIGLAAVCIAIAVVAEPEAFGLVPQDASAPNFIPYGNRIELFIGTFVGAITFSGSVIAF
GKLSGKYRFRLFQGAPVVYPGQHLINLMLALAMLGFGILFFITQSWLPFGIMTAIAFALGVLIIIPIGGADMPVVVSMLN
SYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGDAAAATAGGAKEQRPVKSGSAEDAS
FMLGNAETVVIVPGYGLAVARAQHALKELTDKLVEKGIDVKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEFG
QVDVVLVLGANDVVNPAAKNDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMVK
SVE

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=493, Percent_Identity=46.0446247464503, Blast_Score=401, Evalue=1e-112,
Organism=Homo sapiens, GI122939153, Length=493, Percent_Identity=46.0446247464503, Blast_Score=401, Evalue=1e-112,
Organism=Escherichia coli, GI1787886, Length=488, Percent_Identity=49.7950819672131, Blast_Score=450, Evalue=1e-127,
Organism=Caenorhabditis elegans, GI17550456, Length=488, Percent_Identity=43.0327868852459, Blast_Score=361, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 50675; Mature: 50543

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTVALIAKQAAWLG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
ANLPLGLALVFGALVIGGAVGAVIAARVEMTKMPELVAAMHSLIGLAAVCIAIAVVAEPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
AFGLVPQDASAPNFIPYGNRIELFIGTFVGAITFSGSVIAFGKLSGKYRFRLFQGAPVVY
HHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCEEE
PGQHLINLMLALAMLGFGILFFITQSWLPFGIMTAIAFALGVLIIIPIGGADMPVVVSML
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGDAAA
HCCCCCCHHCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCHHH
ATAGGAKEQRPVKSGSAEDASFMLGNAETVVIVPGYGLAVARAQHALKELTDKLVEKGID
HCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
VKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEFGQVDVVLVLGANDVVNPAAK
EEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCC
NDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMV
CCCCCCCCCCCHHHHHCCEEEEEECHHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHH
KSVE
HHCC
>Mature Secondary Structure 
SMNVVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAILTTVALIAKQAAWLG
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
ANLPLGLALVFGALVIGGAVGAVIAARVEMTKMPELVAAMHSLIGLAAVCIAIAVVAEPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
AFGLVPQDASAPNFIPYGNRIELFIGTFVGAITFSGSVIAFGKLSGKYRFRLFQGAPVVY
HHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCEEE
PGQHLINLMLALAMLGFGILFFITQSWLPFGIMTAIAFALGVLIIIPIGGADMPVVVSML
CCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
NSYSGWAAAGIGFSLNNAMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGDAAA
HCCCCCCHHCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCHHH
ATAGGAKEQRPVKSGSAEDASFMLGNAETVVIVPGYGLAVARAQHALKELTDKLVEKGID
HCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
VKYAIHPVAGRMPGHMNVLLAEAEVPYEIVHEMEDINGEFGQVDVVLVLGANDVVNPAAK
EEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCC
NDPKSPIAGMPIIEAYKARTVIVNKRSMAAGYAGLDNELFYMDKTMMVFGDAKKVIEDMV
CCCCCCCCCCCHHHHHCCEEEEEECHHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHH
KSVE
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]