Click here to switch to the map view.

The map label for this gene is speE [H]

Identifier: 126451669

GI number: 126451669

Start: 1150573

End: 1151769

Strand: Direct

Name: speE [H]

Synonym: BURPS1106A_1170

Alternate gene names: 126451669

Gene position: 1150573-1151769 (Clockwise)

Preceding gene: 126453694

Following gene: 126452521

Centisome position: 28.85

GC content: 68.42

Gene sequence:

>1197_bases
TTGACGCATGCGTGCGCCGCGTGCGCGCGCCGCGTGCGCGGCGCGGTTCAGGCTCGGGCGTTTCCCGTTCGTTTTCGCGC
CGGTCCACGCGAATTCGCGCCCGTTCGCGCCCGTTCGCGTCGCCGCGCATCGTTTCGTCCTGCTTCGCATCGCGCCGCGC
AACGCGGCCCGATGAAGCGGGCCAGCCGGCGGATTCGCCGGCGCGCGGCCCCGCGGGTGCTATCCTCTCGTTCGCTCAAA
CAGCCCCATTCAGCAAGAGACTCATCCATGACCCGACTCATCAAGCGCGCGTCCGCCGAAGCGCGTGCGTTCCGGCGCGC
GAAGCCGTCTCCGTTCAACGGCTCGGAGAAGCTCAAGCCGCCGCGCGCGAAGCGCGCCCGCGCCCAGTTCGGCGACGACT
TCGACCTGGGCGGCGTCGCCGTCCTCGACGAGCCGCGCAAGCCGCGCTTCGCGCCCGTCACGTTCTCCGAAGAGCGCGGT
GTGCGCTATCTGCATTTCGGCACCGAGTGGGTGCAGGGCGCGATGCGCCTGTCGAAGCCGTATCACATCGAGCTCGAGTA
CGCGCAGCAGATGATGGCGTGGCTGCTCTTTCTCGAAACGCCGAAGCGCGTCGTCCAGCTCGGGCTCGGCACGGGCGCGC
TAACGAAATTCGCGCACCGCTTCCTGCCGCGCGCGCATGTCGAGGCGGTGGAGCTGAATCCGGCCGTGATCGTCGCCGCG
CGCTCGATGTTCGCGCTGCCGCCCGACGATGCGCGCCTGAGCATCCACGAAGCGGACGCGTGGGATTTCGTCAATGATCC
GAAGAATCGCGGCGCGATCGGCGCGCTGCAGATCGACCTGTACGACGCGACCGCGCGCGGCCCGGTGCTCGACAGCGTCG
CGTTCTATCGCGCGGTGCGCGCTTGCCTCGCCGACGCGGGCATCGCGACGATCAACCTGTTCGGCGACCATCCGAGCTTC
GTGCGCAACATGAAGCATCTGAACGCGGCGTTCGACCAGCGCGTGATCGCGCTGCCCGAGGTACACGACGGCAACCGGAT
CGCACTCGCGTTCTCCGGCCCGCCGCTGTCGATCTCGTTCGCCCAGTTGACCGAACGCGCGAAGCTGATCGAAGCTAAGC
TGCGCCTGCCCGCGCGTTCGTGGGTGAAAGGTTTGAAAGCGTCGTTCGGCGAGCGTGCCGGCGTCTTCACGATCTGA

Upstream 100 bases:

>100_bases
GCGCGGCGGGGTTCGATACGCTCGTGCTGCCGTCGTCGAGCCCGGCGAATGCGATGCTGTCGTTCGAGCAGAAGCTGGTT
TTCTGGCAGCGTATCGTCGG

Downstream 100 bases:

>100_bases
CACGCGAGCGCGGGGGCCGCCGGGGCCCTCCGCGCGACGCTCCGGGTTCGCCCTCGTTTGCCGCCGTTTTTTCGGCTCCT
ATACTGGCCGACGCCAGGGG

Product: hypothetical protein

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTHACAACARRVRGAVQARAFPVRFRAGPREFAPVRARSRRRASFRPASHRAAQRGPMKRASRRIRRRAAPRVLSSRSLK
QPHSARDSSMTRLIKRASAEARAFRRAKPSPFNGSEKLKPPRAKRARAQFGDDFDLGGVAVLDEPRKPRFAPVTFSEERG
VRYLHFGTEWVQGAMRLSKPYHIELEYAQQMMAWLLFLETPKRVVQLGLGTGALTKFAHRFLPRAHVEAVELNPAVIVAA
RSMFALPPDDARLSIHEADAWDFVNDPKNRGAIGALQIDLYDATARGPVLDSVAFYRAVRACLADAGIATINLFGDHPSF
VRNMKHLNAAFDQRVIALPEVHDGNRIALAFSGPPLSISFAQLTERAKLIEAKLRLPARSWVKGLKASFGERAGVFTI

Sequences:

>Translated_398_residues
MTHACAACARRVRGAVQARAFPVRFRAGPREFAPVRARSRRRASFRPASHRAAQRGPMKRASRRIRRRAAPRVLSSRSLK
QPHSARDSSMTRLIKRASAEARAFRRAKPSPFNGSEKLKPPRAKRARAQFGDDFDLGGVAVLDEPRKPRFAPVTFSEERG
VRYLHFGTEWVQGAMRLSKPYHIELEYAQQMMAWLLFLETPKRVVQLGLGTGALTKFAHRFLPRAHVEAVELNPAVIVAA
RSMFALPPDDARLSIHEADAWDFVNDPKNRGAIGALQIDLYDATARGPVLDSVAFYRAVRACLADAGIATINLFGDHPSF
VRNMKHLNAAFDQRVIALPEVHDGNRIALAFSGPPLSISFAQLTERAKLIEAKLRLPARSWVKGLKASFGERAGVFTI
>Mature_397_residues
THACAACARRVRGAVQARAFPVRFRAGPREFAPVRARSRRRASFRPASHRAAQRGPMKRASRRIRRRAAPRVLSSRSLKQ
PHSARDSSMTRLIKRASAEARAFRRAKPSPFNGSEKLKPPRAKRARAQFGDDFDLGGVAVLDEPRKPRFAPVTFSEERGV
RYLHFGTEWVQGAMRLSKPYHIELEYAQQMMAWLLFLETPKRVVQLGLGTGALTKFAHRFLPRAHVEAVELNPAVIVAAR
SMFALPPDDARLSIHEADAWDFVNDPKNRGAIGALQIDLYDATARGPVLDSVAFYRAVRACLADAGIATINLFGDHPSFV
RNMKHLNAAFDQRVIALPEVHDGNRIALAFSGPPLSISFAQLTERAKLIEAKLRLPARSWVKGLKASFGERAGVFTI

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

Organism=Homo sapiens, GI42542405, Length=221, Percent_Identity=24.4343891402715, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI42542403, Length=221, Percent_Identity=24.4343891402715, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 44321; Mature: 44190

Theoretical pI: Translated: 11.93; Mature: 11.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHACAACARRVRGAVQARAFPVRFRAGPREFAPVRARSRRRASFRPASHRAAQRGPMKR
CCHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCHHHH
ASRRIRRRAAPRVLSSRSLKQPHSARDSSMTRLIKRASAEARAFRRAKPSPFNGSEKLKP
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PRAKRARAQFGDDFDLGGVAVLDEPRKPRFAPVTFSEERGVRYLHFGTEWVQGAMRLSKP
CHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEECCCCCCEEEECCHHHHHHHHHCCCC
YHIELEYAQQMMAWLLFLETPKRVVQLGLGTGALTKFAHRFLPRAHVEAVELNPAVIVAA
CEEEHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCCHHCCEEEECCCEEEEEE
RSMFALPPDDARLSIHEADAWDFVNDPKNRGAIGALQIDLYDATARGPVLDSVAFYRAVR
HHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHH
ACLADAGIATINLFGDHPSFVRNMKHLNAAFDQRVIALPEVHDGNRIALAFSGPPLSISF
HHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHCCEEECCCCCCCCEEEEEECCCCCEEEH
AQLTERAKLIEAKLRLPARSWVKGLKASFGERAGVFTI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
THACAACARRVRGAVQARAFPVRFRAGPREFAPVRARSRRRASFRPASHRAAQRGPMKR
CHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCHHHH
ASRRIRRRAAPRVLSSRSLKQPHSARDSSMTRLIKRASAEARAFRRAKPSPFNGSEKLKP
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PRAKRARAQFGDDFDLGGVAVLDEPRKPRFAPVTFSEERGVRYLHFGTEWVQGAMRLSKP
CHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEECCCCCCEEEECCHHHHHHHHHCCCC
YHIELEYAQQMMAWLLFLETPKRVVQLGLGTGALTKFAHRFLPRAHVEAVELNPAVIVAA
CEEEHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCCHHCCEEEECCCEEEEEE
RSMFALPPDDARLSIHEADAWDFVNDPKNRGAIGALQIDLYDATARGPVLDSVAFYRAVR
HHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHH
ACLADAGIATINLFGDHPSFVRNMKHLNAAFDQRVIALPEVHDGNRIALAFSGPPLSISF
HHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHCCEEECCCCCCCCEEEEEECCCCCEEEH
AQLTERAKLIEAKLRLPARSWVKGLKASFGERAGVFTI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]