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The map label for this gene is yaeL [C]

Identifier: 126451617

GI number: 126451617

Start: 2438540

End: 2439931

Strand: Reverse

Name: yaeL [C]

Synonym: BURPS1106A_2485

Alternate gene names: 126451617

Gene position: 2439931-2438540 (Counterclockwise)

Preceding gene: 126454965

Following gene: 126452465

Centisome position: 61.17

GC content: 68.97

Gene sequence:

>1392_bases
ATGAACGTGCTGGTCGAACTGATCGCGTTTGCTGTGGCGATCGGCGTGCTGGTCGTCGTGCATGAGTACGGGCATTACCG
CGTCGCGCGCTGGTGCGGCGTCAAGGTGCTGCGTTTCTCGATCGGCTTCGGCGCGCCCGTCGCGCGCTGGGTCAGCAAGA
AGACGGGCACCGAGTGGACGCTGTCCGCGCTGCCGCTCGGCGGCTACGTGAAGATGCTCGACGAGCGGGACCCCGGCGAC
GGCATTCGCGCGGACGAGCTGCCGCATGCATTCAACCGGCAGCCGGTCGGCAAGCGGATCGCGATCGTCGCGGCCGGGCC
GGTCGCGAACTTCCTGCTCGCGATCGCGCTCTTCTCGGCCGTGTTCGCGACCGGCGTGACGGAGCCCGCGGCGATCGTCG
CGCCGCCCGCGGCCGGCACGCCCGCCGCGGTCGCGGGCTTTGACGGCGGCGAGACGATCGTGTCGATCCGCATCCCGGGC
GCGGGCGGCGCGCAAGGAGGACAGGCCGAGCCGGTGCGCTCGTGGTCCGAGCTGCGCTGGAAGCTGCTCGGCGCGGCGTT
CGACCACAGGGACGTCGTGCTCGGCGCGCGCAACCGCGCGGACGGCGCCACCTACGATTTTCGCGTCGATCTGCACGGCA
TCGCCGATCGCGACGTCGACGACGATTTCATGTCGCGCCTCGGCTTCGAGCCGGGCGGCGGATCGCTGACGGTGACGTCG
GTGCTGCCGGGCGGCGCCGCGCAACGGGCGGGGCTTCAGGCGGGCGACAAGCTCGTGGCGCTCGACGGCGCGCGCATCGG
CGGCTCGACGCGCTTCATCGACGACGTGAAGGCGCACGCGGGCCGCGCACTCGCGCTGCGCATCGAGCGCGCGGGTGCCG
AGCGCACGGTGTCGATCGTGCCGCAGGCGCAGCGCGACGACGAGACGGGCAAGCAGGTGGGCCGCATCGGCGCGGCGCTC
GCGCTGCAGACGCCGAGCGTGGACGTGCGCTACGGCGTACTCGAGAGCGTCGAGCTCGGCGCGCGGCGCACGTGGGACAT
TTCGGTGTATTCGCTGAAGATGTTCGGCAGGATGGTGACGGGCGAGGCGTCGCTGAAGAACCTGTCCGGCCCGGTGACGA
TCGCCGATTACGCGGGCAAGAGCGCGCGGCTCGGTTTGTCGGCTTTCCTATCGTTTCTCGCCCTTGTCAGCATTAGCCTC
GGCGTGCTGAACTTGCTGCCGATTCCCGTTTTGGACGGGGGGCATCTGTTATATTATCTGGTTGAAGCCGCGACCGGCAA
GGCCGTATCGGAGCGCTGGCAACTGATTCTGCAAAGAGCGGGGTTGATCTGCATCGTCGCGTTGTCGGCGATCGCGCTGT
TCAACGATCTGGCTCGGTTAATCCATTTTTGA

Upstream 100 bases:

>100_bases
TCGAGGCCGACGCCGCCGCGCGCCGCGCGGCGACGGCGTTCATCGGCAAGCTGCCCGCGCCCGGCGTCGAGCGCGCCGCC
TGAATGGAGTCGACACGCTC

Downstream 100 bases:

>100_bases
CGCGTCGGGCGGCAGCCGTAACGGTGGCCGCCTGATCTGATGCAAGCTTAAACACTGGGGATGCATGTTGTTCAAACCTC
ATCGCTTCGTACCTAAGACG

Product: membrane-associated zinc metalloprotease, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MNVLVELIAFAVAIGVLVVVHEYGHYRVARWCGVKVLRFSIGFGAPVARWVSKKTGTEWTLSALPLGGYVKMLDERDPGD
GIRADELPHAFNRQPVGKRIAIVAAGPVANFLLAIALFSAVFATGVTEPAAIVAPPAAGTPAAVAGFDGGETIVSIRIPG
AGGAQGGQAEPVRSWSELRWKLLGAAFDHRDVVLGARNRADGATYDFRVDLHGIADRDVDDDFMSRLGFEPGGGSLTVTS
VLPGGAAQRAGLQAGDKLVALDGARIGGSTRFIDDVKAHAGRALALRIERAGAERTVSIVPQAQRDDETGKQVGRIGAAL
ALQTPSVDVRYGVLESVELGARRTWDISVYSLKMFGRMVTGEASLKNLSGPVTIADYAGKSARLGLSAFLSFLALVSISL
GVLNLLPIPVLDGGHLLYYLVEAATGKAVSERWQLILQRAGLICIVALSAIALFNDLARLIHF

Sequences:

>Translated_463_residues
MNVLVELIAFAVAIGVLVVVHEYGHYRVARWCGVKVLRFSIGFGAPVARWVSKKTGTEWTLSALPLGGYVKMLDERDPGD
GIRADELPHAFNRQPVGKRIAIVAAGPVANFLLAIALFSAVFATGVTEPAAIVAPPAAGTPAAVAGFDGGETIVSIRIPG
AGGAQGGQAEPVRSWSELRWKLLGAAFDHRDVVLGARNRADGATYDFRVDLHGIADRDVDDDFMSRLGFEPGGGSLTVTS
VLPGGAAQRAGLQAGDKLVALDGARIGGSTRFIDDVKAHAGRALALRIERAGAERTVSIVPQAQRDDETGKQVGRIGAAL
ALQTPSVDVRYGVLESVELGARRTWDISVYSLKMFGRMVTGEASLKNLSGPVTIADYAGKSARLGLSAFLSFLALVSISL
GVLNLLPIPVLDGGHLLYYLVEAATGKAVSERWQLILQRAGLICIVALSAIALFNDLARLIHF
>Mature_463_residues
MNVLVELIAFAVAIGVLVVVHEYGHYRVARWCGVKVLRFSIGFGAPVARWVSKKTGTEWTLSALPLGGYVKMLDERDPGD
GIRADELPHAFNRQPVGKRIAIVAAGPVANFLLAIALFSAVFATGVTEPAAIVAPPAAGTPAAVAGFDGGETIVSIRIPG
AGGAQGGQAEPVRSWSELRWKLLGAAFDHRDVVLGARNRADGATYDFRVDLHGIADRDVDDDFMSRLGFEPGGGSLTVTS
VLPGGAAQRAGLQAGDKLVALDGARIGGSTRFIDDVKAHAGRALALRIERAGAERTVSIVPQAQRDDETGKQVGRIGAAL
ALQTPSVDVRYGVLESVELGARRTWDISVYSLKMFGRMVTGEASLKNLSGPVTIADYAGKSARLGLSAFLSFLALVSISL
GVLNLLPIPVLDGGHLLYYLVEAATGKAVSERWQLILQRAGLICIVALSAIALFNDLARLIHF

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=466, Percent_Identity=39.4849785407725, Blast_Score=290, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 48830; Mature: 48830

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLVELIAFAVAIGVLVVVHEYGHYRVARWCGVKVLRFSIGFGAPVARWVSKKTGTEWT
CHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCEEEEEEECCCCCHHHHHHHHCCCCCEE
LSALPLGGYVKMLDERDPGDGIRADELPHAFNRQPVGKRIAIVAAGPVANFLLAIALFSA
EEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
VFATGVTEPAAIVAPPAAGTPAAVAGFDGGETIVSIRIPGAGGAQGGQAEPVRSWSELRW
HHHHCCCCCCEEEECCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHH
KLLGAAFDHRDVVLGARNRADGATYDFRVDLHGIADRDVDDDFMSRLGFEPGGGSLTVTS
HHHHHHCCCCEEEEECCCCCCCCEEEEEEEEECCCCCCCCHHHHHHCCCCCCCCCEEEEE
VLPGGAAQRAGLQAGDKLVALDGARIGGSTRFIDDVKAHAGRALALRIERAGAERTVSIV
ECCCCCHHHCCCCCCCEEEEEECCEECCCCHHHHHHHHHCCCEEEEEEECCCCCCEEEEC
PQAQRDDETGKQVGRIGAALALQTPSVDVRYGVLESVELGARRTWDISVYSLKMFGRMVT
CCCCCCCHHHHHHHHHHHEEEEECCCCEEECCHHHHHHCCCCEEEEEEEEEHHHHHHHHC
GEASLKNLSGPVTIADYAGKSARLGLSAFLSFLALVSISLGVLNLLPIPVLDGGHLLYYL
CCHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEE
VEAATGKAVSERWQLILQRAGLICIVALSAIALFNDLARLIHF
EHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNVLVELIAFAVAIGVLVVVHEYGHYRVARWCGVKVLRFSIGFGAPVARWVSKKTGTEWT
CHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHCEEEEEEECCCCCHHHHHHHHCCCCCEE
LSALPLGGYVKMLDERDPGDGIRADELPHAFNRQPVGKRIAIVAAGPVANFLLAIALFSA
EEECCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHH
VFATGVTEPAAIVAPPAAGTPAAVAGFDGGETIVSIRIPGAGGAQGGQAEPVRSWSELRW
HHHHCCCCCCEEEECCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHH
KLLGAAFDHRDVVLGARNRADGATYDFRVDLHGIADRDVDDDFMSRLGFEPGGGSLTVTS
HHHHHHCCCCEEEEECCCCCCCCEEEEEEEEECCCCCCCCHHHHHHCCCCCCCCCEEEEE
VLPGGAAQRAGLQAGDKLVALDGARIGGSTRFIDDVKAHAGRALALRIERAGAERTVSIV
ECCCCCHHHCCCCCCCEEEEEECCEECCCCHHHHHHHHHCCCEEEEEEECCCCCCEEEEC
PQAQRDDETGKQVGRIGAALALQTPSVDVRYGVLESVELGARRTWDISVYSLKMFGRMVT
CCCCCCCHHHHHHHHHHHEEEEECCCCEEECCHHHHHHCCCCEEEEEEEEEHHHHHHHHC
GEASLKNLSGPVTIADYAGKSARLGLSAFLSFLALVSISLGVLNLLPIPVLDGGHLLYYL
CCHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEE
VEAATGKAVSERWQLILQRAGLICIVALSAIALFNDLARLIHF
EHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]