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The map label for this gene is comA [H]

Identifier: 126451566

GI number: 126451566

Start: 2596255

End: 2598825

Strand: Reverse

Name: comA [H]

Synonym: BURPS1106A_2636

Alternate gene names: 126451566

Gene position: 2598825-2596255 (Counterclockwise)

Preceding gene: 126452641

Following gene: 126453958

Centisome position: 65.16

GC content: 76.16

Gene sequence:

>2571_bases
ATGGACATGCGCCGCTCGGGCGGCGCGCAAGGCGGAGGCGCGATGCGGGCGAAGTGCGGCGCGTTCGCGCTCGGCGTGGT
CGCGCTGCAGCAGCAGGCGGCGTTGCCGGGCGCGGCGGCATGGGCGGGCGGTGCGCTCGCGTTCGGCTTGTGCGTGTGGC
TCGCGCTCGTGTGGCGCGGCGATGCGCGGGCGCGAGCGGCCGGGTTTTGCGCATGCTGCTGCGCGGCGGCGCTCGCGGGC
TTCGGCTATGCCGCGGCGCGCGCGCAGTGGCGGCTCGCCGATACGCTGCCCGCGCAGTGGGAAGGGCGCGACATCGTCGT
GACGGGCGCCGTGCGCGGGCTGCCGTCGCGCGACGCGAACGGCGTGCGTTTCCTGTTCGACGTCGACGCAAACGATGCGC
GCATTGCACGTTTTCCGGCGACGCTGTCGCTTGGCTGGTACGCGTTCGGCCGCCCGGGCGCGCAGCCGCCCGAACTCGTG
CCGGGCGACCGGTGGCGGCTGCGCGTGCGTCTGAAACGCCCGCACGGCAATGCGAATTTCGGCGTGCGCGACGCGGAGGC
GGCGTGGCTCGCGCGCGGCATCCGGGCGCTCGGCTACGTGTCGGCGCCGCGCGATGCGCGGCGGCTCGCGGGGCGTGCAT
CCGGCGTCGCGGCCGCGCTCGACCGGCTGCGCGCGCGGCTGCGCGGGCGCATCGCCGAGGCGCTCGGCGACGCCGCGCAT
CGCGGGATCGTCGTCGCGCTCGCGATCGGCGCGCAGGACGATATCGCCGACGACGACCGGCGCATCCTGCGCGATACCGG
CACGAGCCATCTCGTCGCGATTTCCGGGCTGCACGTCGGGATGGTCGGGGGCCTGTGCGCGTGGCTCGCGGGCGGGCTCT
GGCGGCGCTCGGGCTACGTCGGACGCGACTGGCCGCTCGTCGTGCCCGCGCAGAAAGTCGCGGCGCTCGGCGCGATCGTC
GGCGGCGCCGGCTATGCGGCGCTCGCGGGCTTCAACGTGCCCGTGCAGCGCGCGTGGTGGATGCTTGCCGCCGCGGGCGT
CGCGTATCTGAGTGCTCGCTCGCTCGCGCCTTCGTCGGTGCTGGCGGCCGCGCTCGGCTGCGTGCTGCTCGTCGATCCGT
GGGCGGTGACGTCGGCGGGGTTCTGGCTGTCGTTCTGCGCGGTCGCGGCGATCCTGGCCGTATCGTCGGGGTGGCGCGCC
CCGCGCGATCTCGACGAGACGCGCGGCGCGCGCCACGCGCTCGGCGGCGTGGGTCACGAAGGCGCGCCGCCGTCGCATCG
CGCGCGGTGGCGCGCCGCGTGCGGATTCGCGTGGGGGTGGGCGGCGCGCGCGTTCCGCCGGCTCGCCCGGCGCGTGCGCG
ATGCCGCGCGGGCGCAGTTCGCGGTGACGATCGCGCTCGCGCCGCTCACCGTACTGTGGTTCGCGCAGATCCCGCTCGCC
GGCCCGCTCGCGAACGCGTTCGCGATTCCGTGGGTCGGCTCGCTCGTCACGCCGATCGTGCTCGCGGGCATCGTGCTGCC
GGCGCCGCTCGACGCGTCCGCATACGCGCTCGCGCATGCACTCGTTCAGGCGCTGATGCGGCTGCTCGACGCGACGGCCG
GCGCGGGGCGCACGGTCTGGATGCTGCCGGCGCCGGACGGCTTCGCGCTCGCCGCGGCGGCGGTGGGCGTCGCGTGGGCG
TTGATGCCGCGCGGCTGGCCGGTGCGCTGCGCGGCGCCGCTCGCGTGGCTGCCGCTCGTCGCGCCGGCGCCGCTTGCGCC
GCCCGACGGCGCGTTCAGGCTGACGGCGCTCGACGTCGGGCAGGGCTCCGCGGTGCTGATCGAGACCGCGCGGCACACGC
TGCTGTTCGACGCGGGCCCGGGGCCGGAGGCGTCGAACGCGGGCGAGCGGATCGTCGTGCCGTTCTTGCGCGCGCGAGGC
GTGCGCGCGCTCGACGCGCTCGTCGTGAGCCACGCGGATTCGGATCACGCGGGCGGCGCACCCGCAGTACTCGGATCGAT
CGCCGTCGCGCAGATGGCGGGCGGGCTGCCGCCGTCGAACCGCCTGTGGCGCGCCGCGCGCGCGGCCGGCGTGGCCGACG
CGCTGCCGTGCGTGGCGGGGCAGCGCTGGCGCTGGGACGGCGTCGAGTTCGACGCGCTATGGCCGGCCGGCGGCCCGCGC
GCGGGCGGCGCGACGAACGCGCAGTCGTGCGTGCTGCGCGTATCGGCGGGCGGGCGCGCGGCGCTCCTGACGGGCGATGT
CGATGCGCGCTCCGAGCGCGCGCTCGTCGCCGGATCGCGCGGCGCGCTCGCCGCGCAGGTGCTCGTCGTGCCGCACCACG
GCAGCCGCACGTCGTCGACTGAGCCTTTCCTCGATTCGGTCAAACCGCGCATTGCAATATTTCAGGTAGGCTACGCCAAC
AGGTTTCACCATCCGCATCCGACCGTCTGGGCGCGCTATGCGGGGCGCGGCATCGAGTTGCCGCGCACCGACCGCGACGG
CGCCGTGCGCGTCGACGTGACATCGAGCGGCGCGCTTGCCGAGCCGGTGCGGTATCGGGACGCGCACCGGCGCTACTGGA
TGGGCCGTTGA

Upstream 100 bases:

>100_bases
CTGCGCGGCATCGGCGTCGATGCGCTTTCCCTATCCACTTCGGCCAACGCGCTCGCCGCGCTGCCGCGGCTCGCGCTTTC
GTCCGCATAATCGGTTCGTC

Downstream 100 bases:

>100_bases
CGCGATGCGGAGGCTACGACAGGGAGACAGCGTCGTTTGAAGGACATCATCCATTTCTCGCATGCGAACGGCTTTCCGGC
GTCCACGTATCGGACGATCT

Product: DNA internalization-related competence protein ComEC/Rec2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 856; Mature: 856

Protein sequence:

>856_residues
MDMRRSGGAQGGGAMRAKCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALVWRGDARARAAGFCACCCAAALAG
FGYAAARAQWRLADTLPAQWEGRDIVVTGAVRGLPSRDANGVRFLFDVDANDARIARFPATLSLGWYAFGRPGAQPPELV
PGDRWRLRVRLKRPHGNANFGVRDAEAAWLARGIRALGYVSAPRDARRLAGRASGVAAALDRLRARLRGRIAEALGDAAH
RGIVVALAIGAQDDIADDDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGLWRRSGYVGRDWPLVVPAQKVAALGAIV
GGAGYAALAGFNVPVQRAWWMLAAAGVAYLSARSLAPSSVLAAALGCVLLVDPWAVTSAGFWLSFCAVAAILAVSSGWRA
PRDLDETRGARHALGGVGHEGAPPSHRARWRAACGFAWGWAARAFRRLARRVRDAARAQFAVTIALAPLTVLWFAQIPLA
GPLANAFAIPWVGSLVTPIVLAGIVLPAPLDASAYALAHALVQALMRLLDATAGAGRTVWMLPAPDGFALAAAAVGVAWA
LMPRGWPVRCAAPLAWLPLVAPAPLAPPDGAFRLTALDVGQGSAVLIETARHTLLFDAGPGPEASNAGERIVVPFLRARG
VRALDALVVSHADSDHAGGAPAVLGSIAVAQMAGGLPPSNRLWRAARAAGVADALPCVAGQRWRWDGVEFDALWPAGGPR
AGGATNAQSCVLRVSAGGRAALLTGDVDARSERALVAGSRGALAAQVLVVPHHGSRTSSTEPFLDSVKPRIAIFQVGYAN
RFHHPHPTVWARYAGRGIELPRTDRDGAVRVDVTSSGALAEPVRYRDAHRRYWMGR

Sequences:

>Translated_856_residues
MDMRRSGGAQGGGAMRAKCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALVWRGDARARAAGFCACCCAAALAG
FGYAAARAQWRLADTLPAQWEGRDIVVTGAVRGLPSRDANGVRFLFDVDANDARIARFPATLSLGWYAFGRPGAQPPELV
PGDRWRLRVRLKRPHGNANFGVRDAEAAWLARGIRALGYVSAPRDARRLAGRASGVAAALDRLRARLRGRIAEALGDAAH
RGIVVALAIGAQDDIADDDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGLWRRSGYVGRDWPLVVPAQKVAALGAIV
GGAGYAALAGFNVPVQRAWWMLAAAGVAYLSARSLAPSSVLAAALGCVLLVDPWAVTSAGFWLSFCAVAAILAVSSGWRA
PRDLDETRGARHALGGVGHEGAPPSHRARWRAACGFAWGWAARAFRRLARRVRDAARAQFAVTIALAPLTVLWFAQIPLA
GPLANAFAIPWVGSLVTPIVLAGIVLPAPLDASAYALAHALVQALMRLLDATAGAGRTVWMLPAPDGFALAAAAVGVAWA
LMPRGWPVRCAAPLAWLPLVAPAPLAPPDGAFRLTALDVGQGSAVLIETARHTLLFDAGPGPEASNAGERIVVPFLRARG
VRALDALVVSHADSDHAGGAPAVLGSIAVAQMAGGLPPSNRLWRAARAAGVADALPCVAGQRWRWDGVEFDALWPAGGPR
AGGATNAQSCVLRVSAGGRAALLTGDVDARSERALVAGSRGALAAQVLVVPHHGSRTSSTEPFLDSVKPRIAIFQVGYAN
RFHHPHPTVWARYAGRGIELPRTDRDGAVRVDVTSSGALAEPVRYRDAHRRYWMGR
>Mature_856_residues
MDMRRSGGAQGGGAMRAKCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALVWRGDARARAAGFCACCCAAALAG
FGYAAARAQWRLADTLPAQWEGRDIVVTGAVRGLPSRDANGVRFLFDVDANDARIARFPATLSLGWYAFGRPGAQPPELV
PGDRWRLRVRLKRPHGNANFGVRDAEAAWLARGIRALGYVSAPRDARRLAGRASGVAAALDRLRARLRGRIAEALGDAAH
RGIVVALAIGAQDDIADDDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGLWRRSGYVGRDWPLVVPAQKVAALGAIV
GGAGYAALAGFNVPVQRAWWMLAAAGVAYLSARSLAPSSVLAAALGCVLLVDPWAVTSAGFWLSFCAVAAILAVSSGWRA
PRDLDETRGARHALGGVGHEGAPPSHRARWRAACGFAWGWAARAFRRLARRVRDAARAQFAVTIALAPLTVLWFAQIPLA
GPLANAFAIPWVGSLVTPIVLAGIVLPAPLDASAYALAHALVQALMRLLDATAGAGRTVWMLPAPDGFALAAAAVGVAWA
LMPRGWPVRCAAPLAWLPLVAPAPLAPPDGAFRLTALDVGQGSAVLIETARHTLLFDAGPGPEASNAGERIVVPFLRARG
VRALDALVVSHADSDHAGGAPAVLGSIAVAQMAGGLPPSNRLWRAARAAGVADALPCVAGQRWRWDGVEFDALWPAGGPR
AGGATNAQSCVLRVSAGGRAALLTGDVDARSERALVAGSRGALAAQVLVVPHHGSRTSSTEPFLDSVKPRIAIFQVGYAN
RFHHPHPTVWARYAGRGIELPRTDRDGAVRVDVTSSGALAEPVRYRDAHRRYWMGR

Specific function: Essential for natural transformation. Could be a transporter involved in DNA uptake [H]

COG id: COG2333

COG function: function code R; Predicted hydrolase (metallo-beta-lactamase superfamily)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ComEC, H.influenzae REC2, and E.coli YcaI [H]

Homologues:

Organism=Escherichia coli, GI87081801, Length=714, Percent_Identity=27.03081232493, Blast_Score=204, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004477
- InterPro:   IPR004797 [H]

Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 89417; Mature: 89417

Theoretical pI: Translated: 11.50; Mature: 11.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMRRSGGAQGGGAMRAKCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALVWRG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHCC
DARARAAGFCACCCAAALAGFGYAAARAQWRLADTLPAQWEGRDIVVTGAVRGLPSRDAN
CCHHHHHHHHHHHHHHHHHHCCHHHHHCCEEECCCCCCCCCCCEEEEEECCCCCCCCCCC
GVRFLFDVDANDARIARFPATLSLGWYAFGRPGAQPPELVPGDRWRLRVRLKRPHGNANF
CEEEEEEECCCCCEEEECCCEEEECEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
GVRDAEAAWLARGIRALGYVSAPRDARRLAGRASGVAAALDRLRARLRGRIAEALGDAAH
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RGIVVALAIGAQDDIADDDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGLWRRSGYV
CCEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCHHHHCCCCC
GRDWPLVVPAQKVAALGAIVGGAGYAALAGFNVPVQRAWWMLAAAGVAYLSARSLAPSSV
CCCCCEEECHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
LAAALGCVLLVDPWAVTSAGFWLSFCAVAAILAVSSGWRAPRDLDETRGARHALGGVGHE
HHHHHCHHEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHCCCCCC
GAPPSHRARWRAACGFAWGWAARAFRRLARRVRDAARAQFAVTIALAPLTVLWFAQIPLA
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHCCCC
GPLANAFAIPWVGSLVTPIVLAGIVLPAPLDASAYALAHALVQALMRLLDATAGAGRTVW
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
MLPAPDGFALAAAAVGVAWALMPRGWPVRCAAPLAWLPLVAPAPLAPPDGAFRLTALDVG
EEECCCCHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHCCCCCCCCCCCCCEEEEEEECC
QGSAVLIETARHTLLFDAGPGPEASNAGERIVVPFLRARGVRALDALVVSHADSDHAGGA
CCCEEEEEECCEEEEEECCCCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHCCCCCCCCCC
PAVLGSIAVAQMAGGLPPSNRLWRAARAAGVADALPCVAGQRWRWDGVEFDALWPAGGPR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHCCCCEECCCEEEEEECCCCCCC
AGGATNAQSCVLRVSAGGRAALLTGDVDARSERALVAGSRGALAAQVLVVPHHGSRTSST
CCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCEEEECCCCCEEEEEEEEECCCCCCCCC
EPFLDSVKPRIAIFQVGYANRFHHPHPTVWARYAGRGIELPRTDRDGAVRVDVTSSGALA
CCHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCC
EPVRYRDAHRRYWMGR
CCHHHHHHHHHHCCCC
>Mature Secondary Structure
MDMRRSGGAQGGGAMRAKCGAFALGVVALQQQAALPGAAAWAGGALAFGLCVWLALVWRG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHCC
DARARAAGFCACCCAAALAGFGYAAARAQWRLADTLPAQWEGRDIVVTGAVRGLPSRDAN
CCHHHHHHHHHHHHHHHHHHCCHHHHHCCEEECCCCCCCCCCCEEEEEECCCCCCCCCCC
GVRFLFDVDANDARIARFPATLSLGWYAFGRPGAQPPELVPGDRWRLRVRLKRPHGNANF
CEEEEEEECCCCCEEEECCCEEEECEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
GVRDAEAAWLARGIRALGYVSAPRDARRLAGRASGVAAALDRLRARLRGRIAEALGDAAH
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RGIVVALAIGAQDDIADDDRRILRDTGTSHLVAISGLHVGMVGGLCAWLAGGLWRRSGYV
CCEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCHHHHCCCCC
GRDWPLVVPAQKVAALGAIVGGAGYAALAGFNVPVQRAWWMLAAAGVAYLSARSLAPSSV
CCCCCEEECHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
LAAALGCVLLVDPWAVTSAGFWLSFCAVAAILAVSSGWRAPRDLDETRGARHALGGVGHE
HHHHHCHHEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHCCCCCC
GAPPSHRARWRAACGFAWGWAARAFRRLARRVRDAARAQFAVTIALAPLTVLWFAQIPLA
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHCCCC
GPLANAFAIPWVGSLVTPIVLAGIVLPAPLDASAYALAHALVQALMRLLDATAGAGRTVW
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
MLPAPDGFALAAAAVGVAWALMPRGWPVRCAAPLAWLPLVAPAPLAPPDGAFRLTALDVG
EEECCCCHHHHHHHHHHHHHHCCCCCCCEECCCHHHHHCCCCCCCCCCCCCEEEEEEECC
QGSAVLIETARHTLLFDAGPGPEASNAGERIVVPFLRARGVRALDALVVSHADSDHAGGA
CCCEEEEEECCEEEEEECCCCCCCCCCCCEEEEEHHHCCCCHHHHHHHHHCCCCCCCCCC
PAVLGSIAVAQMAGGLPPSNRLWRAARAAGVADALPCVAGQRWRWDGVEFDALWPAGGPR
HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHCCCCEECCCEEEEEECCCCCCC
AGGATNAQSCVLRVSAGGRAALLTGDVDARSERALVAGSRGALAAQVLVVPHHGSRTSST
CCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCEEEECCCCCEEEEEEEEECCCCCCCCC
EPFLDSVKPRIAIFQVGYANRFHHPHPTVWARYAGRGIELPRTDRDGAVRVDVTSSGALA
CCHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCC
EPVRYRDAHRRYWMGR
CCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934834; 8830266 [H]