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The map label for this gene is 126445517

Identifier: 126445517

GI number: 126445517

Start: 1336962

End: 1338653

Strand: Reverse

Name: 126445517

Synonym: BURPS668_A1426

Alternate gene names: NA

Gene position: 1338653-1336962 (Counterclockwise)

Preceding gene: 126443305

Following gene: 126443097

Centisome position: 42.8

GC content: 70.74

Gene sequence:

>1692_bases
ATGAACAAGAAACGTAGTAATCCTGAACAGACGCGGCTTGGCCAGGTCCGTGCCGTCGCCGGCATTCTCTCCATGTCCGT
CCTCGTTCCGCTCGCCGGTTGCGGCGGCGGTGGCGACGGAGGCGGAAGCGGCACGCCGTCGGCCGCCGCGCAGCCGACCC
CCGCGCCGGCGCCGGCGCCGGCCCCGGCACCCGCGCCGAGCTCGGGTTCGTCGCAATCCACCAATTCGTCGACCTCGACG
GCGGCCTGCCCCGTCACGCAGGCCGCCTCGACCGCCGCCAGCGAAACGCTCGTCACCCGCACCGTTTCGCACGAAGCGCC
CGTCGATCATCTGATCGTCAAGCTGCAACGCACGGCGGCGGCGAGCGCATCCGGCGCGCGCATCATGGCCGCGGCGAACG
ACGCGGCCCGACTCGATTCGGTGATCCAGCGCGTGATGTCGCAATGGAGCGCGAAGAGCGGCGCCGTTCGCTCGTATGCG
CAGAACATCGCGCCGACGAACGCGGTGCAGGTGGAACGGACGATGTCGGACGGTGCCGCGCTGCTCGCGCTCGGACAAAA
GATGAGCGCGGATAATGCCGGCGCTCTCGCGCAAACGTTCGCGGCCGATCCGGACGTCGCCTATGCGGAGCCCGACCGGC
GCGTGTTCGCCCGCACGGTGGCGACCGACCCGGACTACGCGCAGCAGTGGAACTACTTCGATCCGGCGGCCGGCATCAAT
CTGCCGGACGCATGGAACGTGACGAACGGCCTGCCGAGCGTCGTCACCGCGGTGCTCGACACCGGCTATCGCCCGCATCC
GGACATCATCGCGAACCTGCTGCCGGGCTACGATTTCATCTCCGACATCAACACCGGCAACAACGGCCACGGCCGCGGCC
CGGATGCGACCGACCCGGGCGACTGGGTCACGCAGCAGGAACTGACCGATCCGTCGAGCCCGTTCTACCAATGCGCGAGC
GCGCCGTCGAACAGCAGCTGGCACGGCACGCAGGTCGCCGGCATCATCGGCGCCGCCGCGAACAACGGCATCGGCATCGC
GGGCGTCAGCTGGTACGGCAAGATCCTGCCCGTGCGCGTGCTCGGCAAGTGCGGCGGCACGACGAGCGACATCGCCGACG
CGATGCGCTGGGCGGCGGGCATTCCCGTCGCGGGCGCGCCGACGAACCTCACGCCGGCGAAGGTGATCAACCTGAGCCTC
GGCGGCACCGGCCCGTGCGGCGACACGTTCCAGCAGGCGATCAACGACGTGATCGCGCGCGGCACGACCGTCGTCGTCTC
GGCCGGCAACGACGGCCAGGCGACGACGCTGGACCGCCCGGCCAACTGCAAGGGCGTGATCTCGGTCGGCGCGACCGACA
GCACCGGCCAGCGCGCGTGGTACAGCAACTTCGGCTCGGACATCACGCTGAGCGCGCCGGGCTCGAACATCCTGTCGACG
AGCAATGCGGGCACCACGGTGCCGACCACCGACGCGTACGGCACGCACAGCGGCACGAGCCTTGCCGCGCCGCAGGTGGC
GGGCGTCGCCTCGCTGATGCTCGCGGTCAACCCGAACCTCACGCCCGCGCAGATCGCGCAGAAGCTCGCGAGCACCGCGC
GGCCGTCGCCGGCCACCGCATCCTGCCTCGCGCGCGCGCCGGGCGCGGGCATCGTCGACGCCGGCACGGTGGTTGCGTCC
GCAACGAAATAG

Upstream 100 bases:

>100_bases
GCGACGAAGAATGAGGATCGTGCTCGCGAAACCCTCACGCCACGGGTCTTGACCGCGTTGACCGCGCATGCGGTATCGAA
CCCAAGAGTGGAGAGGCCCC

Downstream 100 bases:

>100_bases
CGTCGCGTCCCGAACGCGCTCTTGCGGCGGCCGCCCGAACGGGCGGCCGTCTTTCTTCGGTTCGCGGCCGCGCCGGCGGC
AATGCGCCGCCTCGCGCGCA

Product: putative serine metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MNKKRSNPEQTRLGQVRAVAGILSMSVLVPLAGCGGGGDGGGSGTPSAAAQPTPAPAPAPAPAPAPSSGSSQSTNSSTST
AACPVTQAASTAASETLVTRTVSHEAPVDHLIVKLQRTAAASASGARIMAAANDAARLDSVIQRVMSQWSAKSGAVRSYA
QNIAPTNAVQVERTMSDGAALLALGQKMSADNAGALAQTFAADPDVAYAEPDRRVFARTVATDPDYAQQWNYFDPAAGIN
LPDAWNVTNGLPSVVTAVLDTGYRPHPDIIANLLPGYDFISDINTGNNGHGRGPDATDPGDWVTQQELTDPSSPFYQCAS
APSNSSWHGTQVAGIIGAAANNGIGIAGVSWYGKILPVRVLGKCGGTTSDIADAMRWAAGIPVAGAPTNLTPAKVINLSL
GGTGPCGDTFQQAINDVIARGTTVVVSAGNDGQATTLDRPANCKGVISVGATDSTGQRAWYSNFGSDITLSAPGSNILST
SNAGTTVPTTDAYGTHSGTSLAAPQVAGVASLMLAVNPNLTPAQIAQKLASTARPSPATASCLARAPGAGIVDAGTVVAS
ATK

Sequences:

>Translated_563_residues
MNKKRSNPEQTRLGQVRAVAGILSMSVLVPLAGCGGGGDGGGSGTPSAAAQPTPAPAPAPAPAPAPSSGSSQSTNSSTST
AACPVTQAASTAASETLVTRTVSHEAPVDHLIVKLQRTAAASASGARIMAAANDAARLDSVIQRVMSQWSAKSGAVRSYA
QNIAPTNAVQVERTMSDGAALLALGQKMSADNAGALAQTFAADPDVAYAEPDRRVFARTVATDPDYAQQWNYFDPAAGIN
LPDAWNVTNGLPSVVTAVLDTGYRPHPDIIANLLPGYDFISDINTGNNGHGRGPDATDPGDWVTQQELTDPSSPFYQCAS
APSNSSWHGTQVAGIIGAAANNGIGIAGVSWYGKILPVRVLGKCGGTTSDIADAMRWAAGIPVAGAPTNLTPAKVINLSL
GGTGPCGDTFQQAINDVIARGTTVVVSAGNDGQATTLDRPANCKGVISVGATDSTGQRAWYSNFGSDITLSAPGSNILST
SNAGTTVPTTDAYGTHSGTSLAAPQVAGVASLMLAVNPNLTPAQIAQKLASTARPSPATASCLARAPGAGIVDAGTVVAS
ATK
>Mature_563_residues
MNKKRSNPEQTRLGQVRAVAGILSMSVLVPLAGCGGGGDGGGSGTPSAAAQPTPAPAPAPAPAPAPSSGSSQSTNSSTST
AACPVTQAASTAASETLVTRTVSHEAPVDHLIVKLQRTAAASASGARIMAAANDAARLDSVIQRVMSQWSAKSGAVRSYA
QNIAPTNAVQVERTMSDGAALLALGQKMSADNAGALAQTFAADPDVAYAEPDRRVFARTVATDPDYAQQWNYFDPAAGIN
LPDAWNVTNGLPSVVTAVLDTGYRPHPDIIANLLPGYDFISDINTGNNGHGRGPDATDPGDWVTQQELTDPSSPFYQCAS
APSNSSWHGTQVAGIIGAAANNGIGIAGVSWYGKILPVRVLGKCGGTTSDIADAMRWAAGIPVAGAPTNLTPAKVINLSL
GGTGPCGDTFQQAINDVIARGTTVVVSAGNDGQATTLDRPANCKGVISVGATDSTGQRAWYSNFGSDITLSAPGSNILST
SNAGTTVPTTDAYGTHSGTSLAAPQVAGVASLMLAVNPNLTPAQIAQKLASTARPSPATASCLARAPGAGIVDAGTVVAS
ATK

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI20336180, Length=421, Percent_Identity=28.2660332541568, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4505577, Length=420, Percent_Identity=27.8571428571429, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI20336182, Length=412, Percent_Identity=27.4271844660194, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI20336190, Length=423, Percent_Identity=27.6595744680851, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI20336184, Length=412, Percent_Identity=27.4271844660194, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI27894285, Length=422, Percent_Identity=27.2511848341232, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI20336188, Length=422, Percent_Identity=27.2511848341232, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI299523015, Length=389, Percent_Identity=26.2210796915167, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI76443679, Length=433, Percent_Identity=26.5588914549654, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI20336186, Length=391, Percent_Identity=27.3657289002558, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI20336246, Length=389, Percent_Identity=26.2210796915167, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI20336242, Length=375, Percent_Identity=26.1333333333333, Blast_Score=66, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71983555, Length=362, Percent_Identity=26.2430939226519, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25141268, Length=362, Percent_Identity=26.2430939226519, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71987206, Length=363, Percent_Identity=29.2011019283747, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320775, Length=218, Percent_Identity=33.9449541284404, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324576, Length=194, Percent_Identity=32.9896907216495, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360987, Length=402, Percent_Identity=25.3731343283582, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24642494, Length=402, Percent_Identity=25.3731343283582, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24642490, Length=402, Percent_Identity=25.3731343283582, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45555723, Length=402, Percent_Identity=25.3731343283582, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24642492, Length=402, Percent_Identity=25.3731343283582, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24642488, Length=404, Percent_Identity=25, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24642484, Length=404, Percent_Identity=25, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24642486, Length=404, Percent_Identity=25, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007280
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF04151 PPC [H]

EC number: NA

Molecular weight: Translated: 56532; Mature: 56532

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKRSNPEQTRLGQVRAVAGILSMSVLVPLAGCGGGGDGGGSGTPSAAAQPTPAPAPAP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APAPAPSSGSSQSTNSSTSTAACPVTQAASTAASETLVTRTVSHEAPVDHLIVKLQRTAA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ASASGARIMAAANDAARLDSVIQRVMSQWSAKSGAVRSYAQNIAPTNAVQVERTMSDGAA
CCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEHHHCCCCE
LLALGQKMSADNAGALAQTFAADPDVAYAEPDRRVFARTVATDPDYAQQWNYFDPAAGIN
EEHHCCCCCCCCCCHHHHHHCCCCCCEECCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCC
LPDAWNVTNGLPSVVTAVLDTGYRPHPDIIANLLPGYDFISDINTGNNGHGRGPDATDPG
CCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCC
DWVTQQELTDPSSPFYQCASAPSNSSWHGTQVAGIIGAAANNGIGIAGVSWYGKILPVRV
CCCCHHHCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHH
LGKCGGTTSDIADAMRWAAGIPVAGAPTNLTPAKVINLSLGGTGPCGDTFQQAINDVIAR
HHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHC
GTTVVVSAGNDGQATTLDRPANCKGVISVGATDSTGQRAWYSNFGSDITLSAPGSNILST
CCEEEEECCCCCCCEECCCCCCCCEEEEECCCCCCCCHHHHHCCCCCEEEECCCCCCEEC
SNAGTTVPTTDAYGTHSGTSLAAPQVAGVASLMLAVNPNLTPAQIAQKLASTARPSPATA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCCHH
SCLARAPGAGIVDAGTVVASATK
HHHHHCCCCCEEECCCEEEECCC
>Mature Secondary Structure
MNKKRSNPEQTRLGQVRAVAGILSMSVLVPLAGCGGGGDGGGSGTPSAAAQPTPAPAPAP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APAPAPSSGSSQSTNSSTSTAACPVTQAASTAASETLVTRTVSHEAPVDHLIVKLQRTAA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ASASGARIMAAANDAARLDSVIQRVMSQWSAKSGAVRSYAQNIAPTNAVQVERTMSDGAA
CCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEHHHCCCCE
LLALGQKMSADNAGALAQTFAADPDVAYAEPDRRVFARTVATDPDYAQQWNYFDPAAGIN
EEHHCCCCCCCCCCHHHHHHCCCCCCEECCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCC
LPDAWNVTNGLPSVVTAVLDTGYRPHPDIIANLLPGYDFISDINTGNNGHGRGPDATDPG
CCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCC
DWVTQQELTDPSSPFYQCASAPSNSSWHGTQVAGIIGAAANNGIGIAGVSWYGKILPVRV
CCCCHHHCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHH
LGKCGGTTSDIADAMRWAAGIPVAGAPTNLTPAKVINLSLGGTGPCGDTFQQAINDVIAR
HHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHC
GTTVVVSAGNDGQATTLDRPANCKGVISVGATDSTGQRAWYSNFGSDITLSAPGSNILST
CCEEEEECCCCCCCEECCCCCCCCEEEEECCCCCCCCHHHHHCCCCCEEEECCCCCCEEC
SNAGTTVPTTDAYGTHSGTSLAAPQVAGVASLMLAVNPNLTPAQIAQKLASTARPSPATA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCCCCHH
SCLARAPGAGIVDAGTVVASATK
HHHHHCCCCCEEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2187155; 12024217 [H]