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The map label for this gene is potC [H]

Identifier: 126445385

GI number: 126445385

Start: 2412804

End: 2413673

Strand: Reverse

Name: potC [H]

Synonym: BURPS668_A2498

Alternate gene names: 126445385

Gene position: 2413673-2412804 (Counterclockwise)

Preceding gene: 126443410

Following gene: 126443115

Centisome position: 77.18

GC content: 66.55

Gene sequence:

>870_bases
ATGAGCGCCGAGCGAACAGGGGAAACGAACATGAAACTGCTGGCGAAGCCGCTCTTCGCGCCGCACATGTCGGGGCTCGA
GCGCGCCTGGTATTTCGCGCTGCGCGGCCTCGTCGTGCTGACGCTCTTGTATCTGATCCTGCCCGTGCTCGCGATCGTGC
CGCTGTCGTTCTCGTCGAGCACGTTCCTCGTCTATCCGATTCCGGGCTTCTCGATGCGCTGGTACGAGAACCTGCTCGCG
TCCGACGAGTGGCGGATGGCCGCGAAGAACAGCTTCATCGTCGCACCCGCCGCGACGCTCGTCGCGACCGTGCTCGGCAC
GCTCGCCGCGATCGGCCTCACGAAGAGCGATTTCCGCGGCAAGGGGCTGCTGATGGCGGTGCTGCTCTCGCCGATGATCG
TGCCCGTCGTCGTCGTGGGCGTCGGCATGTATCTGTTCTTCGCGCCGCTCGGGCTTGCGAACACCTACACGGGGCTCATC
TGCGCGCACGCGGCGCTCGGCGTGCCGTTCGTCGTGACGACGGTCGCCGCGACGCTGCAGGGCTTCAATCAGAATCTCGT
GCGCGCGAGCCTGTCGCTCGGCGCGAACCCGGTGACGACGTTCTTCCGCGTGACGCTGCCCGTGATCGCGCCGGGCGTGA
TGTCGGGCGCGCTGTTCGCGTTCGCGACGTCGTTCGACGAAGTGGTCGTCACGCTGTTTCTCGCTGGCGCCGATCAGACG
ACGCTGCCGCGCCAGATGTTCACCGGCATTCGCGAGAACATCAGCCCGACGATCGCCGCGCTCGCGACGATCCTGATCGT
GTTCTCGACGTGTCTGCTGCTCGCGCTCGAATGGCTGCGCGGACGCCATGCGAAGCGCGCGGTGAGCTGA

Upstream 100 bases:

>100_bases
GGGCATGGCGTGTGCGCTCGGCGGCCTGCTGCTCGCCGCGACGCTCGTGCTGTATGCGATCTACGGCCGCTTTACGCGCT
CGCAATTGAGCCTCGGCTGA

Downstream 100 bases:

>100_bases
TGCGTCGGCCGCGTGCGGCGCGTCCTCCGTACGCGCCGCGTTGCGCCGGCCGCTTGCCGCCACCGCTTGCCGCTGTCGCG
CTATGCGCGCCCGTTCAATT

Product: putative polyamine ABC transporter permease

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MSAERTGETNMKLLAKPLFAPHMSGLERAWYFALRGLVVLTLLYLILPVLAIVPLSFSSSTFLVYPIPGFSMRWYENLLA
SDEWRMAAKNSFIVAPAATLVATVLGTLAAIGLTKSDFRGKGLLMAVLLSPMIVPVVVVGVGMYLFFAPLGLANTYTGLI
CAHAALGVPFVVTTVAATLQGFNQNLVRASLSLGANPVTTFFRVTLPVIAPGVMSGALFAFATSFDEVVVTLFLAGADQT
TLPRQMFTGIRENISPTIAALATILIVFSTCLLLALEWLRGRHAKRAVS

Sequences:

>Translated_289_residues
MSAERTGETNMKLLAKPLFAPHMSGLERAWYFALRGLVVLTLLYLILPVLAIVPLSFSSSTFLVYPIPGFSMRWYENLLA
SDEWRMAAKNSFIVAPAATLVATVLGTLAAIGLTKSDFRGKGLLMAVLLSPMIVPVVVVGVGMYLFFAPLGLANTYTGLI
CAHAALGVPFVVTTVAATLQGFNQNLVRASLSLGANPVTTFFRVTLPVIAPGVMSGALFAFATSFDEVVVTLFLAGADQT
TLPRQMFTGIRENISPTIAALATILIVFSTCLLLALEWLRGRHAKRAVS
>Mature_288_residues
SAERTGETNMKLLAKPLFAPHMSGLERAWYFALRGLVVLTLLYLILPVLAIVPLSFSSSTFLVYPIPGFSMRWYENLLAS
DEWRMAAKNSFIVAPAATLVATVLGTLAAIGLTKSDFRGKGLLMAVLLSPMIVPVVVVGVGMYLFFAPLGLANTYTGLIC
AHAALGVPFVVTTVAATLQGFNQNLVRASLSLGANPVTTFFRVTLPVIAPGVMSGALFAFATSFDEVVVTLFLAGADQTT
LPRQMFTGIRENISPTIAALATILIVFSTCLLLALEWLRGRHAKRAVS

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=230, Percent_Identity=32.6086956521739, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1787081, Length=241, Percent_Identity=32.7800829875519, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787714, Length=240, Percent_Identity=32.9166666666667, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788764, Length=235, Percent_Identity=29.3617021276596, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787080, Length=134, Percent_Identity=29.1044776119403, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30943; Mature: 30812

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAERTGETNMKLLAKPLFAPHMSGLERAWYFALRGLVVLTLLYLILPVLAIVPLSFSSS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TFLVYPIPGFSMRWYENLLASDEWRMAAKNSFIVAPAATLVATVLGTLAAIGLTKSDFRG
EEEEEECCCCCHHHHHHHHCCCHHHHHHCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCC
KGLLMAVLLSPMIVPVVVVGVGMYLFFAPLGLANTYTGLICAHAALGVPFVVTTVAATLQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GFNQNLVRASLSLGANPVTTFFRVTLPVIAPGVMSGALFAFATSFDEVVVTLFLAGADQT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TLPRQMFTGIRENISPTIAALATILIVFSTCLLLALEWLRGRHAKRAVS
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCC
>Mature Secondary Structure 
SAERTGETNMKLLAKPLFAPHMSGLERAWYFALRGLVVLTLLYLILPVLAIVPLSFSSS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TFLVYPIPGFSMRWYENLLASDEWRMAAKNSFIVAPAATLVATVLGTLAAIGLTKSDFRG
EEEEEECCCCCHHHHHHHHCCCHHHHHHCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCC
KGLLMAVLLSPMIVPVVVVGVGMYLFFAPLGLANTYTGLICAHAALGVPFVVTTVAATLQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
GFNQNLVRASLSLGANPVTTFFRVTLPVIAPGVMSGALFAFATSFDEVVVTLFLAGADQT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TLPRQMFTGIRENISPTIAALATILIVFSTCLLLALEWLRGRHAKRAVS
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]