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The map label for this gene is lsrR [H]

Identifier: 126445383

GI number: 126445383

Start: 413611

End: 414630

Strand: Reverse

Name: lsrR [H]

Synonym: BURPS668_A0453

Alternate gene names: 126445383

Gene position: 414630-413611 (Counterclockwise)

Preceding gene: 126442535

Following gene: 126445469

Centisome position: 13.26

GC content: 67.94

Gene sequence:

>1020_bases
ATGACGCGCACCGCGGTTCATGACGCCGCGCAGCGCGCCGCTCCACTCGATCACGACATGACGAACGAAGAACTCACGCA
ACTCGCAAAGTGCTATTACGTCGACGGGTTGACGCAGGAAGAACTCGCGCAGAAGTTCGCGATCTCGCGCCCGAAGGTGG
GCCGGCTGCTCAAGCGCGCGATCGAAGAGGGCATCGTCGAGATTCGCGTGCGCCATCATCCGCGCGCGGTGCAGGATCTC
GAACAGGAGCTGGTCACGCGCTTCGGCATCCAGCGCGCGATCATCTCGGTCGACCACAAGGATCAGGACAGCCAGCGCGA
GCTGCTCGCGGGGCTCGTCGCGAGCTACCTCGACCGCGTGCTCGCGGACGGGGCGATCGTCGCGGTCGGCATGGGCCGCA
ACGTGAGCGCGGTGTCGCGGCACGCGGTATCGACGACGCAGCGCAACTGCTCGTTCGTTTCCGCGATCGGCGGCTCGTAT
CGCGGCGGCGAGACGATGAACGCCGACCACATCTGCCGGCGCCTCGCCGCGCGCTTCGGCGGCGAGAGCGAGACACTGTA
CGCGCCGGCGCTCGTCAATGATCCGCAGCTCTTCACCGCGCTGCTCGAGAACGACGTCGTGCGCCAGTCGCTCGACAAGG
CGCGCCGCGCGTCGATCGCGCTCGTCGGCATCGGCGACATTCTCGAGGACAGCAACATGGTCCGCATGGGCTGGTTCACG
CCCGAGGAAATGGCCGAGGCAAAGCGCGCGGGCGCCGTCGGCGACATCATGGGCTACGACTTCATCGACATCCACGGCCG
CCCGGCGACGACGATGCTGCGCGGCCGCGTGATCGGGCTCACGCTCGAAGACCTGAAGCGGATTCCGAACGTGATCGCGA
CCGCGAGCGAGCCGACGAAAGCCACGGGCATTCTCGGCGCGCTGCGCGCCGGCGTGATCAACACGCTCGCGACCACGCAG
TCGATCGCGCAGACGGTGCTGAGCCTCGCGCAGGCCACCGAGACGGCGAGCGCGGCGTAG

Upstream 100 bases:

>100_bases
GCATGGCTTAGGGCAGAATTCGACGGCGGCCGCTCGCAGCCGAAGGTGCAGCGGATCGCCGACTACGAACGCCGGGCGGG
CCTCACCCAGGCCGGCCCGA

Downstream 100 bases:

>100_bases
CGCGCGCTTCATGCGCCGGCCGCGCGAAACGGCCGGCGCACGCGCGCCGCGTGCGTCAGAACGTGTGACGCACGCCGATG
CGCACGAGCGTCTGCGTATC

Product: DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTRTAVHDAAQRAAPLDHDMTNEELTQLAKCYYVDGLTQEELAQKFAISRPKVGRLLKRAIEEGIVEIRVRHHPRAVQDL
EQELVTRFGIQRAIISVDHKDQDSQRELLAGLVASYLDRVLADGAIVAVGMGRNVSAVSRHAVSTTQRNCSFVSAIGGSY
RGGETMNADHICRRLAARFGGESETLYAPALVNDPQLFTALLENDVVRQSLDKARRASIALVGIGDILEDSNMVRMGWFT
PEEMAEAKRAGAVGDIMGYDFIDIHGRPATTMLRGRVIGLTLEDLKRIPNVIATASEPTKATGILGALRAGVINTLATTQ
SIAQTVLSLAQATETASAA

Sequences:

>Translated_339_residues
MTRTAVHDAAQRAAPLDHDMTNEELTQLAKCYYVDGLTQEELAQKFAISRPKVGRLLKRAIEEGIVEIRVRHHPRAVQDL
EQELVTRFGIQRAIISVDHKDQDSQRELLAGLVASYLDRVLADGAIVAVGMGRNVSAVSRHAVSTTQRNCSFVSAIGGSY
RGGETMNADHICRRLAARFGGESETLYAPALVNDPQLFTALLENDVVRQSLDKARRASIALVGIGDILEDSNMVRMGWFT
PEEMAEAKRAGAVGDIMGYDFIDIHGRPATTMLRGRVIGLTLEDLKRIPNVIATASEPTKATGILGALRAGVINTLATTQ
SIAQTVLSLAQATETASAA
>Mature_338_residues
TRTAVHDAAQRAAPLDHDMTNEELTQLAKCYYVDGLTQEELAQKFAISRPKVGRLLKRAIEEGIVEIRVRHHPRAVQDLE
QELVTRFGIQRAIISVDHKDQDSQRELLAGLVASYLDRVLADGAIVAVGMGRNVSAVSRHAVSTTQRNCSFVSAIGGSYR
GGETMNADHICRRLAARFGGESETLYAPALVNDPQLFTALLENDVVRQSLDKARRASIALVGIGDILEDSNMVRMGWFTP
EEMAEAKRAGAVGDIMGYDFIDIHGRPATTMLRGRVIGLTLEDLKRIPNVIATASEPTKATGILGALRAGVINTLATTQS
IAQTVLSLAQATETASAA

Specific function: In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFGE operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho- AI-2, leading to the transcription of the lsr genes [H]

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=319, Percent_Identity=28.8401253918495, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI87082414, Length=327, Percent_Identity=26.605504587156, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 36684; Mature: 36553

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTAVHDAAQRAAPLDHDMTNEELTQLAKCYYVDGLTQEELAQKFAISRPKVGRLLKRA
CCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
IEEGIVEIRVRHHPRAVQDLEQELVTRFGIQRAIISVDHKDQDSQRELLAGLVASYLDRV
HHCCHHEEHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LADGAIVAVGMGRNVSAVSRHAVSTTQRNCSFVSAIGGSYRGGETMNADHICRRLAARFG
HCCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
GESETLYAPALVNDPQLFTALLENDVVRQSLDKARRASIALVGIGDILEDSNMVRMGWFT
CCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHHHCCCCEEEEECCC
PEEMAEAKRAGAVGDIMGYDFIDIHGRPATTMLRGRVIGLTLEDLKRIPNVIATASEPTK
HHHHHHHHHCCCHHHHHCCCEEEECCCCHHHHHHCEEEEEEHHHHHHHHHHHHCCCCCCH
ATGILGALRAGVINTLATTQSIAQTVLSLAQATETASAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRTAVHDAAQRAAPLDHDMTNEELTQLAKCYYVDGLTQEELAQKFAISRPKVGRLLKRA
CCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
IEEGIVEIRVRHHPRAVQDLEQELVTRFGIQRAIISVDHKDQDSQRELLAGLVASYLDRV
HHCCHHEEHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
LADGAIVAVGMGRNVSAVSRHAVSTTQRNCSFVSAIGGSYRGGETMNADHICRRLAARFG
HCCCCEEEEECCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHC
GESETLYAPALVNDPQLFTALLENDVVRQSLDKARRASIALVGIGDILEDSNMVRMGWFT
CCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECHHHHCCCCEEEEECCC
PEEMAEAKRAGAVGDIMGYDFIDIHGRPATTMLRGRVIGLTLEDLKRIPNVIATASEPTK
HHHHHHHHHCCCHHHHHCCCEEEECCCCHHHHHHCEEEEEEHHHHHHHHHHHHCCCCCCH
ATGILGALRAGVINTLATTQSIAQTVLSLAQATETASAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA