Click here to switch to the map view.

The map label for this gene is pcp [H]

Identifier: 126445010

GI number: 126445010

Start: 2134032

End: 2135621

Strand: Reverse

Name: pcp [H]

Synonym: BURPS668_A2202

Alternate gene names: 126445010

Gene position: 2135621-2134032 (Counterclockwise)

Preceding gene: 126444025

Following gene: 126442856

Centisome position: 68.29

GC content: 72.08

Gene sequence:

>1590_bases
ATGGCAAGGCATCTTCACGCCGGCAACGAATCGCATCTCGTCGCCGAATCCACGTGCATCGGGCCGTGCGATCCGGCCGA
GACGATTCATGTAGTGGTGATGTTGCGGCGACAGCAAGAGCAGCACCTCGATTCATTGTTGCAGGGCCTCGCGAGCGGCG
ATCCGGGCGTGAAGCCTGTCTCGCGCGAGGCGTTCGCCCAGCGTTTCGGCGCGCATCCCGACGACGTCATGAAAGTCGAG
GCATTCGCGCAGCAGCGCGGCCTCGCGGTCGCGCGCGTCGATCCGGTCGAGAGCCTCGTCGTGCTGTCGGGCACGATCGC
GCAGTTCGAGGCGGCCTTCGGCGTGAAGCTCGAGCGCTTCGAGCATCGGTCGATCGGCCAGTATCGCGGCCGCACGGGCG
ATATCACGCTGCCCGACGAGTTGCACGGCATCGTCACCGCGGTGCTCGGGCTCGACGATCGCCCGCAGGCCCGGCCGCAT
TTCCGGCTGCGGCCGACTTTCCTGCCCGCGCGCGCGCCGGCCGTCACCTACACGCCGCCGCAGCTCGCGGCCCTCTACGA
TTTCCCGCCCGGCGACGGCGCGGGCCAGTGCATCGCGATCGTCGAGCTCGGCGGCGGCTATCGGCCGGCCGAGATCCAGC
AGTATTTCGGCGGCCTCGGGCTCGCGCGGCAGCCGAAGCTCGTCGACGTGAGCGTCGGCGCGGGGCGCAACGCGCCGACG
GGCGATCCGAGCGGGCCGGACGGCGAAGTCGCGCTCGATATCGAGATCGCGGGCGCGATCGCGCCCGGCGCGACGATTGC
CGTCTATTTCGCGCAGAACAGCGACGCCGGCTTCATCCAGGCGGTCAATCAGGCGGTGCACGACACGACGAACCGGCCCT
CCGTCGTGTCGATCAGTTGGGGCGCGGCGGAGGCGAACTGGACGTCGCAATCGATCCAGGCCTTCGATCGCGTGCTGCAG
TCGGCCGCGGCGCTCGGCGTGACCGTGTGCGCGGCGTCCGGCGATGACGGCTCGAACGACGGCCTGCAGGACGGCACGAA
TCACGTCGATTTCCCGGCATCGAGCCCGTACGTGCTCGCGTGCGGCGGCACGCGGCTCGACGCGCTGCCGGGGCAGGGCA
TCCGCAGCGAAGTGGTGTGGAACGACGAGGCGGCGGGCGGCGGCGCGACGGGCGGCGGCGTCAGCGCCGTGTTCGACGTG
CCGCAGTGGCAGAGCGGCCTGAGCGCGACGCTCGCGCAGGGCGGCGGCGCGTCGCCGCTCGTGAAGCGCGGCGTGCCGGA
CGTCGCGGGCGATGCGTCGCCCGCGACGGGCTACGAGGTGTTCGTCGCGGGCACGTCGACGGTGATGGGCGGCACGAGCG
CCGTCGCACCGCTGTGGGCCGCGCTCGTCGCGCGGATCAATGCGGCGGCGGGCAGCCCCGCGGGCTGGATCAACCCGAAG
CTGTACCGGAACGCGGGCGCGCTGCACGACATCTCGGTGGGCGATAACGGCGCGTATGCGGCGACGCCGGGCTGGGACGC
GTGCACGGGGCTCGGCAGCCCGGACGGCGCGAAGGTCGCGGCGGCGCTGAAGGGCGGCGCGGCGGGCTGA

Upstream 100 bases:

>100_bases
CGGCGTGTGTGCGCCGTCCGACATACCGCCCGGAACTGCGATCGCGCGACCGTGTCCGAATCCTGGCAATTCGTCACCAC
GGCTTCTGGAGGGTCCGAAT

Downstream 100 bases:

>100_bases
TTGACGGCAAGCCGAGGCGACGGTGCGCGGCGGCTTGCACGCCGCGCCTGGGCGCCGCTGCGGCCGCGGGCGCGCGCATC
GGATGCGGCGGCGCGCAGGT

Product: serine protease

Products: NA

Alternate protein names: Pepstatin-insensitive carboxyl proteinase; Pseudomonapepsin [H]

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MARHLHAGNESHLVAESTCIGPCDPAETIHVVVMLRRQQEQHLDSLLQGLASGDPGVKPVSREAFAQRFGAHPDDVMKVE
AFAQQRGLAVARVDPVESLVVLSGTIAQFEAAFGVKLERFEHRSIGQYRGRTGDITLPDELHGIVTAVLGLDDRPQARPH
FRLRPTFLPARAPAVTYTPPQLAALYDFPPGDGAGQCIAIVELGGGYRPAEIQQYFGGLGLARQPKLVDVSVGAGRNAPT
GDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDTTNRPSVVSISWGAAEANWTSQSIQAFDRVLQ
SAAALGVTVCAASGDDGSNDGLQDGTNHVDFPASSPYVLACGGTRLDALPGQGIRSEVVWNDEAAGGGATGGGVSAVFDV
PQWQSGLSATLAQGGGASPLVKRGVPDVAGDASPATGYEVFVAGTSTVMGGTSAVAPLWAALVARINAAAGSPAGWINPK
LYRNAGALHDISVGDNGAYAATPGWDACTGLGSPDGAKVAAALKGGAAG

Sequences:

>Translated_529_residues
MARHLHAGNESHLVAESTCIGPCDPAETIHVVVMLRRQQEQHLDSLLQGLASGDPGVKPVSREAFAQRFGAHPDDVMKVE
AFAQQRGLAVARVDPVESLVVLSGTIAQFEAAFGVKLERFEHRSIGQYRGRTGDITLPDELHGIVTAVLGLDDRPQARPH
FRLRPTFLPARAPAVTYTPPQLAALYDFPPGDGAGQCIAIVELGGGYRPAEIQQYFGGLGLARQPKLVDVSVGAGRNAPT
GDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDTTNRPSVVSISWGAAEANWTSQSIQAFDRVLQ
SAAALGVTVCAASGDDGSNDGLQDGTNHVDFPASSPYVLACGGTRLDALPGQGIRSEVVWNDEAAGGGATGGGVSAVFDV
PQWQSGLSATLAQGGGASPLVKRGVPDVAGDASPATGYEVFVAGTSTVMGGTSAVAPLWAALVARINAAAGSPAGWINPK
LYRNAGALHDISVGDNGAYAATPGWDACTGLGSPDGAKVAAALKGGAAG
>Mature_528_residues
ARHLHAGNESHLVAESTCIGPCDPAETIHVVVMLRRQQEQHLDSLLQGLASGDPGVKPVSREAFAQRFGAHPDDVMKVEA
FAQQRGLAVARVDPVESLVVLSGTIAQFEAAFGVKLERFEHRSIGQYRGRTGDITLPDELHGIVTAVLGLDDRPQARPHF
RLRPTFLPARAPAVTYTPPQLAALYDFPPGDGAGQCIAIVELGGGYRPAEIQQYFGGLGLARQPKLVDVSVGAGRNAPTG
DPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDTTNRPSVVSISWGAAEANWTSQSIQAFDRVLQS
AAALGVTVCAASGDDGSNDGLQDGTNHVDFPASSPYVLACGGTRLDALPGQGIRSEVVWNDEAAGGGATGGGVSAVFDVP
QWQSGLSATLAQGGGASPLVKRGVPDVAGDASPATGYEVFVAGTSTVMGGTSAVAPLWAALVARINAAAGSPAGWINPKL
YRNAGALHDISVGDNGAYAATPGWDACTGLGSPDGAKVAAALKGGAAG

Specific function: Unknown

COG id: COG4934

COG function: function code O; Predicted protease

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S53 family [H]

Homologues:

Organism=Homo sapiens, GI5729770, Length=566, Percent_Identity=26.3250883392226, Blast_Score=85, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015366
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR009020 [H]

Pfam domain/function: PF00082 Peptidase_S8; PF09286 Pro-kuma_activ [H]

EC number: =3.4.21.100 [H]

Molecular weight: Translated: 54064; Mature: 53933

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARHLHAGNESHLVAESTCIGPCDPAETIHVVVMLRRQQEQHLDSLLQGLASGDPGVKPV
CCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SREAFAQRFGAHPDDVMKVEAFAQQRGLAVARVDPVESLVVLSGTIAQFEAAFGVKLERF
CHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCHHHHHHHHHCCCHHHH
EHRSIGQYRGRTGDITLPDELHGIVTAVLGLDDRPQARPHFRLRPTFLPARAPAVTYTPP
HHHCHHHHCCCCCCEECCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCEEEECCC
QLAALYDFPPGDGAGQCIAIVELGGGYRPAEIQQYFGGLGLARQPKLVDVSVGAGRNAPT
CCEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCC
GDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDTTNRPSVVSISW
CCCCCCCCCEEEEEEEECEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEC
GAAEANWTSQSIQAFDRVLQSAAALGVTVCAASGDDGSNDGLQDGTNHVDFPASSPYVLA
CCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEE
CGGTRLDALPGQGIRSEVVWNDEAAGGGATGGGVSAVFDVPQWQSGLSATLAQGGGASPL
ECCCEECCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCHHCCHHHHHHCCCCCCHH
VKRGVPDVAGDASPATGYEVFVAGTSTVMGGTSAVAPLWAALVARINAAAGSPAGWINPK
HHCCCCCCCCCCCCCCCEEEEEEECCEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCH
LYRNAGALHDISVGDNGAYAATPGWDACTGLGSPDGAKVAAALKGGAAG
HHHCCCCEEEEECCCCCCEECCCCCHHHCCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
ARHLHAGNESHLVAESTCIGPCDPAETIHVVVMLRRQQEQHLDSLLQGLASGDPGVKPV
CCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SREAFAQRFGAHPDDVMKVEAFAQQRGLAVARVDPVESLVVLSGTIAQFEAAFGVKLERF
CHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHCHHHHHHHHHCCCHHHH
EHRSIGQYRGRTGDITLPDELHGIVTAVLGLDDRPQARPHFRLRPTFLPARAPAVTYTPP
HHHCHHHHCCCCCCEECCHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCEEEECCC
QLAALYDFPPGDGAGQCIAIVELGGGYRPAEIQQYFGGLGLARQPKLVDVSVGAGRNAPT
CCEEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCC
GDPSGPDGEVALDIEIAGAIAPGATIAVYFAQNSDAGFIQAVNQAVHDTTNRPSVVSISW
CCCCCCCCCEEEEEEEECEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEC
GAAEANWTSQSIQAFDRVLQSAAALGVTVCAASGDDGSNDGLQDGTNHVDFPASSPYVLA
CCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEE
CGGTRLDALPGQGIRSEVVWNDEAAGGGATGGGVSAVFDVPQWQSGLSATLAQGGGASPL
ECCCEECCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCHHCCHHHHHHCCCCCCHH
VKRGVPDVAGDASPATGYEVFVAGTSTVMGGTSAVAPLWAALVARINAAAGSPAGWINPK
HHCCCCCCCCCCCCCCCEEEEEEECCEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCH
LYRNAGALHDISVGDNGAYAATPGWDACTGLGSPDGAKVAAALKGGAAG
HHHCCCCEEEEECCCCCCEECCCCCHHHCCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7929375; 8576087; 10488127; 11747435; 11323721 [H]