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The map label for this gene is phnW [H]

Identifier: 126444998

GI number: 126444998

Start: 549117

End: 550226

Strand: Reverse

Name: phnW [H]

Synonym: BURPS668_A0582

Alternate gene names: 126444998

Gene position: 550226-549117 (Counterclockwise)

Preceding gene: 126442991

Following gene: 126442980

Centisome position: 17.59

GC content: 72.25

Gene sequence:

>1110_bases
ATGCCAGAACGTGATCCCATCCTGTTGACGCCCGGCCCGCTGACGACCTCGCGCATGACGCGCGACGCGATGCTGCGCGA
CTGGGGCTCGTGGGACGCCGCTTTCAACCGGCTGACGAAGAGCGTCTGCGCGGATCTCGTGCGGATCGCGGGCGGCGGCG
ACGCATATGTGTGCGTGCCGCTGCAAGGCAGCGGCACGTTTGCGGTCGAAGCGACGCTCGGCACGCTCGTGCCGCGCGAC
GCCCGCGTGCTCGTGCCGAACAATGGCGCGTACTGCGCGCGGATCGCGGCGATCCTGCGCCGGCTCGGCGTCGCGCACGT
CGAGCTGCCGTTCGCCGAGGACGAGCCGGCGAGCGCGCACGCGATCGACGCGGCGCTCGCGCGCGACGCGCGCCTCACGC
ACGTCGCGCTCGTGCATCTGGAGACGAGCGCCGGCCTGCTGAACCCGCTCGACGACATCGCCGCCGTCTGCCGCGCGCGC
GGCAAGGCGCTGATCGTCGATGCGATGAGCTCGTTCGGTGCGCTGCCGATCGCGCTCGCGGCAAGCGGCATCGACGCGCT
GATCTCGGCGAGCGGCAAGTGCCTGGAAGGAGTGCCCGGCATGGGCTTCGCGATCGTGCGGCGTTCGGCGCTCGAAGCGG
CCGAGGGGCGCTCGCCTTCGGTCGCGCTCGATCTGCACGACCAGTACGCATACATGCAGCGCACGTCGCAATGGCGCTTC
ACGCCGCCGACGCACGTGCTCGCCGCGCTGCGCGCCGCGCTCGACCAGTTCTTCGACGAAGGCGGGCAGCCGGCGCGCGG
CGCGCGCTACGCGCGGAACTGCGCGACGCTCGTCGACGGCATGCGCGCGCTCGGCTTCGAGCCGTTTCTCGACGCGCGCG
CGCAGGCGAGCGTGATCGTCACGTTCTACGCGCCCGCCGATCCCGCGTATGCGTTCCCGGCGTTCTACGCGGCCGTGCGC
GACGCGGGCTACGTGCTGTATCCGGGCAAGCTGACGACGGCCGACACGTTTCGCGTCGGCTGCATCGGCGCGCTCGGCGC
CGACGAGATGCGCGGCGCGGTGGCGGCGATCGGCGGCGCGCTCGAATCGCTCGGAATCGCGATGCGGTGA

Upstream 100 bases:

>100_bases
TCCGTGACGATTGACTTCATTTCCAAAAAACGACACATTTCGCCACTATCCTCCACATCCATCGACCACTGTTCCCGATC
TTTTCCGGAGTGACGAAGCC

Downstream 100 bases:

>100_bases
CGGGGAAGCAGTGAAGTCGCAAAGGGAAAGCGCGGGCCGCGGCGCGAAGGCGGGAACGACCAGTCGAGCGTTGCGGGCCA
TGCCCTGCCGTTATCGGGTT

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT [H]

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MPERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVPLQGSGTFAVEATLGTLVPRD
ARVLVPNNGAYCARIAAILRRLGVAHVELPFAEDEPASAHAIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRAR
GKALIVDAMSSFGALPIALAASGIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRF
TPPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIVTFYAPADPAYAFPAFYAAVR
DAGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGALESLGIAMR

Sequences:

>Translated_369_residues
MPERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVPLQGSGTFAVEATLGTLVPRD
ARVLVPNNGAYCARIAAILRRLGVAHVELPFAEDEPASAHAIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRAR
GKALIVDAMSSFGALPIALAASGIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRF
TPPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIVTFYAPADPAYAFPAFYAAVR
DAGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGALESLGIAMR
>Mature_368_residues
PERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVPLQGSGTFAVEATLGTLVPRDA
RVLVPNNGAYCARIAAILRRLGVAHVELPFAEDEPASAHAIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRARG
KALIVDAMSSFGALPIALAASGIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRFT
PPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIVTFYAPADPAYAFPAFYAAVRD
AGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGALESLGIAMR

Specific function: Involved in phosphonate degradation [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=307, Percent_Identity=26.7100977198697, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17536281, Length=306, Percent_Identity=23.8562091503268, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.37 [H]

Molecular weight: Translated: 38817; Mature: 38686

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVP
CCCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
LQGSGTFAVEATLGTLVPRDARVLVPNNGAYCARIAAILRRLGVAHVELPFAEDEPASAH
ECCCCCEEEEEEHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHH
AIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRARGKALIVDAMSSFGALPIALA
HHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECHHHCCCCHHHHH
ASGIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRF
HHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHCCCCCC
TPPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIV
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEEEE
TFYAPADPAYAFPAFYAAVRDAGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGA
EEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
LESLGIAMR
HHHCCCCCC
>Mature Secondary Structure 
PERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVP
CCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
LQGSGTFAVEATLGTLVPRDARVLVPNNGAYCARIAAILRRLGVAHVELPFAEDEPASAH
ECCCCCEEEEEEHHHCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHH
AIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRARGKALIVDAMSSFGALPIALA
HHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECHHHCCCCHHHHH
ASGIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRF
HHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHCCCCCC
TPPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIV
CCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEEEE
TFYAPADPAYAFPAFYAAVRDAGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGA
EEECCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
LESLGIAMR
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA