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The map label for this gene is ttuB [H]

Identifier: 126444798

GI number: 126444798

Start: 1836802

End: 1838097

Strand: Reverse

Name: ttuB [H]

Synonym: BURPS668_A1884

Alternate gene names: 126444798

Gene position: 1838097-1836802 (Counterclockwise)

Preceding gene: 126442370

Following gene: 126445472

Centisome position: 58.77

GC content: 68.98

Gene sequence:

>1296_bases
GTGGACGAAACCTCAATCCGCGAACGGGCGGTCATGGCGAAGATCGCGCGGCGGCTGATGCCGCTGCTCGTCATCATGTT
CCTGATCGCGTTCATCGACCGGCAGAACGTCGGTTTCGCGAAGCTGCAGATGGTCCACGCGCTTGGGATGACCGAGACGT
CGTACGGGCTCGGCGCGTCGCTGTTCTTCATCGGCTACCTGCTGTTCGAGGTGCCGAGCACGCTCGCGCTGCATCGGTTC
GGCGCGCGCCTCTGGCTCGCGCGCATCATGATGACGTGGGGTGTGATCACGGTGCTGCTCGGCTTCACGCATTCGACGGG
CGTCTTCTACGTATTCCGCTTTCTGCTCGGCGTCGCGGAAGCCGGCTTCTATCCGGGAGTCATCTATTACCTGACGCTGT
GGTTTCCGCAAAGCCACCGCACGCGCGTGCTCGGCCTCTTCACGCTCGGCAGCGCGCTCGCGAACATGCTCGGCTCGCTC
GCGGGCGGGCTGCTGCTGTCGCTCGACGGCCGGCTCGGGCTCGCCGGCTGGCAGTGGGTATTCGTCGCGACGGGGTTGCC
CGCCATCGCCGTCGCGCTCGTCGCATGGCGTTACTTGCCGGAATCGGTCGAGCGCGCGACGTTCCTGTCCGACGACGAGA
AGCGCGTCGCGCTCGCCGCGCTCAAGCGCGAGGCGTCGCCCGAGGCGGTGTCCGAATCGCCGTGGCGCGCGCTCGTCGAT
CCGCGCGTGCTGATGTTCGCGCTCGCGTACATGCTGATGTCGACGTCGCTGTACGGCGTCACGTACTGGCTGCCGACGCT
GTTGAAGAGCAACGGCGTGCCGTCGTCGCTGAACGGACTGCTGAACATGATTCCCTGGGCGATCGCGGCGCTGCTGCTGC
TGTGGCTGCCCGCGCGGCTCAAGCGCGAGCGGATCGTGCTCAAGGCAATGGCGGCCGTCGCGGGCGTCGGCGTGGCGGGC
TTCGCGCTCAGTCTCGCGCTGCCCGGCCTGCCTCTGCGCTTCGCCGCGCTCGTGCTGGGCGGCGCGTGCATTCCGCTGCT
GTATCCGTGCTTCTGGTCGCTGCCGCCGCGCTTTTTCTCCGGCGCGCGCGCCGCGGCGAGCATCGCCGCGATCAACTCGA
TCGGCAATCTCGGCGGATTTTTCGCGCAGAACCTGATGCCGTACGTCGGCAAGGCGGCGGGCAGCGCCGGCGCGCCGATG
CTCGTGCCTGTCGTGTGCCTGGCGGCGCTCGGCGTGGGCATGCTCGCCGCCGCGTCGATGGCCGGCCGGCGGGGGCCGGC
CGGCATGGCGGCCTGA

Upstream 100 bases:

>100_bases
CGCTTTCCCGTTTCAGGCAGGTTGCACGGGTAATTCCGCATTGTCTCACTCAATTGATCAACTAATCATCTATATGAATT
ATCGAGCAAGGAGACGGCTG

Downstream 100 bases:

>100_bases
CGAACGCCGGTTGACGCGGCGGCGGCGTCTCGGGCGAGCCGGAGCGCGCGTCGCCGCGAGTCTGTCCGGGCGGCGTTGCG
CGAGCGCGCGCCGCCCGGTT

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MDETSIRERAVMAKIARRLMPLLVIMFLIAFIDRQNVGFAKLQMVHALGMTETSYGLGASLFFIGYLLFEVPSTLALHRF
GARLWLARIMMTWGVITVLLGFTHSTGVFYVFRFLLGVAEAGFYPGVIYYLTLWFPQSHRTRVLGLFTLGSALANMLGSL
AGGLLLSLDGRLGLAGWQWVFVATGLPAIAVALVAWRYLPESVERATFLSDDEKRVALAALKREASPEAVSESPWRALVD
PRVLMFALAYMLMSTSLYGVTYWLPTLLKSNGVPSSLNGLLNMIPWAIAALLLLWLPARLKRERIVLKAMAAVAGVGVAG
FALSLALPGLPLRFAALVLGGACIPLLYPCFWSLPPRFFSGARAAASIAAINSIGNLGGFFAQNLMPYVGKAAGSAGAPM
LVPVVCLAALGVGMLAAASMAGRRGPAGMAA

Sequences:

>Translated_431_residues
MDETSIRERAVMAKIARRLMPLLVIMFLIAFIDRQNVGFAKLQMVHALGMTETSYGLGASLFFIGYLLFEVPSTLALHRF
GARLWLARIMMTWGVITVLLGFTHSTGVFYVFRFLLGVAEAGFYPGVIYYLTLWFPQSHRTRVLGLFTLGSALANMLGSL
AGGLLLSLDGRLGLAGWQWVFVATGLPAIAVALVAWRYLPESVERATFLSDDEKRVALAALKREASPEAVSESPWRALVD
PRVLMFALAYMLMSTSLYGVTYWLPTLLKSNGVPSSLNGLLNMIPWAIAALLLLWLPARLKRERIVLKAMAAVAGVGVAG
FALSLALPGLPLRFAALVLGGACIPLLYPCFWSLPPRFFSGARAAASIAAINSIGNLGGFFAQNLMPYVGKAAGSAGAPM
LVPVVCLAALGVGMLAAASMAGRRGPAGMAA
>Mature_431_residues
MDETSIRERAVMAKIARRLMPLLVIMFLIAFIDRQNVGFAKLQMVHALGMTETSYGLGASLFFIGYLLFEVPSTLALHRF
GARLWLARIMMTWGVITVLLGFTHSTGVFYVFRFLLGVAEAGFYPGVIYYLTLWFPQSHRTRVLGLFTLGSALANMLGSL
AGGLLLSLDGRLGLAGWQWVFVATGLPAIAVALVAWRYLPESVERATFLSDDEKRVALAALKREASPEAVSESPWRALVD
PRVLMFALAYMLMSTSLYGVTYWLPTLLKSNGVPSSLNGLLNMIPWAIAALLLLWLPARLKRERIVLKAMAAVAGVGVAG
FALSLALPGLPLRFAALVLGGACIPLLYPCFWSLPPRFFSGARAAASIAAINSIGNLGGFFAQNLMPYVGKAAGSAGAPM
LVPVVCLAALGVGMLAAASMAGRRGPAGMAA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=384, Percent_Identity=34.6354166666667, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI2367379, Length=433, Percent_Identity=23.5565819861432, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082320, Length=305, Percent_Identity=23.6065573770492, Blast_Score=78, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6322025, Length=349, Percent_Identity=26.647564469914, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321698, Length=273, Percent_Identity=22.7106227106227, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319876, Length=308, Percent_Identity=24.025974025974, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321502, Length=245, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319250, Length=235, Percent_Identity=23.4042553191489, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322612, Length=297, Percent_Identity=26.2626262626263, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46191; Mature: 46191

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDETSIRERAVMAKIARRLMPLLVIMFLIAFIDRQNVGFAKLQMVHALGMTETSYGLGAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHH
LFFIGYLLFEVPSTLALHRFGARLWLARIMMTWGVITVLLGFTHSTGVFYVFRFLLGVAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AGFYPGVIYYLTLWFPQSHRTRVLGLFTLGSALANMLGSLAGGLLLSLDGRLGLAGWQWV
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHH
FVATGLPAIAVALVAWRYLPESVERATFLSDDEKRVALAALKREASPEAVSESPWRALVD
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHC
PRVLMFALAYMLMSTSLYGVTYWLPTLLKSNGVPSSLNGLLNMIPWAIAALLLLWLPARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KRERIVLKAMAAVAGVGVAGFALSLALPGLPLRFAALVLGGACIPLLYPCFWSLPPRFFS
HHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHC
GARAAASIAAINSIGNLGGFFAQNLMPYVGKAAGSAGAPMLVPVVCLAALGVGMLAAASM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AGRRGPAGMAA
HCCCCCCCCCC
>Mature Secondary Structure
MDETSIRERAVMAKIARRLMPLLVIMFLIAFIDRQNVGFAKLQMVHALGMTETSYGLGAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHH
LFFIGYLLFEVPSTLALHRFGARLWLARIMMTWGVITVLLGFTHSTGVFYVFRFLLGVAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AGFYPGVIYYLTLWFPQSHRTRVLGLFTLGSALANMLGSLAGGLLLSLDGRLGLAGWQWV
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHH
FVATGLPAIAVALVAWRYLPESVERATFLSDDEKRVALAALKREASPEAVSESPWRALVD
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHC
PRVLMFALAYMLMSTSLYGVTYWLPTLLKSNGVPSSLNGLLNMIPWAIAALLLLWLPARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KRERIVLKAMAAVAGVGVAGFALSLALPGLPLRFAALVLGGACIPLLYPCFWSLPPRFFS
HHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCHHHHC
GARAAASIAAINSIGNLGGFFAQNLMPYVGKAAGSAGAPMLVPVVCLAALGVGMLAAASM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AGRRGPAGMAA
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]