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The map label for this gene is ptp [H]

Identifier: 126444661

GI number: 126444661

Start: 2519797

End: 2520243

Strand: Reverse

Name: ptp [H]

Synonym: BURPS668_A2621

Alternate gene names: 126444661

Gene position: 2520243-2519797 (Counterclockwise)

Preceding gene: 126444725

Following gene: 126445515

Centisome position: 80.58

GC content: 65.77

Gene sequence:

>447_bases
ATGGGTTCGAGCATGTTTCGCAACATTCTGATCGTATGCCGCGCGAACGTGTGCCGCAGCCCGGCCGCGGAGTTGCTGTT
CAGGTCGATGGCGCCGCGCGCGTCGCTTGCATTCCATTCGGCGGGCATCGACGCGAACGACGGCGACGACATCGATCCGA
CGATGTCGCGCCTGCTCGCGGAGCGCGGCGTCGACGCGGCGCCGCACCGTTCGCGGCGGCTGAGCCGCGCGCTCGTGCGC
GCCGCGGATCTCGTGCTCGTCACCGAGCGCCGGCAAATCACCGAAGTCGAGGCGATCGATCCGTTCGCGCGCGGCAAGGT
GCATCTGCTCGGCAAATGGGAGGACGCGGAGATCGCCGATCCGCACGGCGGTCCCGAGGCCGATTATCGGGAGAGCTACA
CATTGATCGAACGTCTCGTTCAAGGATGGCTGCAAAAGATATGCTGA

Upstream 100 bases:

>100_bases
GAGTACTACCCGATCGGGCGGCCCGGCGCGGCGCCGCGCACGGCGGCGGGCGAGTCCGACGCCGCTCGCGCCGCGCGCGT
CGGCGCGTGAGCGGGCCGCC

Downstream 100 bases:

>100_bases
ATCGTTCGCTTAGACCCCTGGCGCTCGCCGTCGCCGCCGCCACGCTGCTGCAGGCGTGCGCGACGGCGCCCGGCAACTAC
CTCGACACGTCGCGTCTCGA

Product: low molecular weight phosphotyrosine protein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MGSSMFRNILIVCRANVCRSPAAELLFRSMAPRASLAFHSAGIDANDGDDIDPTMSRLLAERGVDAAPHRSRRLSRALVR
AADLVLVTERRQITEVEAIDPFARGKVHLLGKWEDAEIADPHGGPEADYRESYTLIERLVQGWLQKIC

Sequences:

>Translated_148_residues
MGSSMFRNILIVCRANVCRSPAAELLFRSMAPRASLAFHSAGIDANDGDDIDPTMSRLLAERGVDAAPHRSRRLSRALVR
AADLVLVTERRQITEVEAIDPFARGKVHLLGKWEDAEIADPHGGPEADYRESYTLIERLVQGWLQKIC
>Mature_147_residues
GSSMFRNILIVCRANVCRSPAAELLFRSMAPRASLAFHSAGIDANDGDDIDPTMSRLLAERGVDAAPHRSRRLSRALVRA
ADLVLVTERRQITEVEAIDPFARGKVHLLGKWEDAEIADPHGGPEADYRESYTLIERLVQGWLQKIC

Specific function: Dephosphorylates ptk. May be involved in the production and the transport of exopolysaccharides [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788375, Length=144, Percent_Identity=40.2777777777778, Blast_Score=104, Evalue=3e-24,
Organism=Escherichia coli, GI87081812, Length=148, Percent_Identity=35.1351351351351, Blast_Score=88, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16439; Mature: 16308

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSSMFRNILIVCRANVCRSPAAELLFRSMAPRASLAFHSAGIDANDGDDIDPTMSRLLA
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHH
ERGVDAAPHRSRRLSRALVRAADLVLVTERRQITEVEAIDPFARGKVHLLGKWEDAEIAD
HCCCCCCCHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCHHHCCCEEEEECCCCCCCCC
PHGGPEADYRESYTLIERLVQGWLQKIC
CCCCCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
GSSMFRNILIVCRANVCRSPAAELLFRSMAPRASLAFHSAGIDANDGDDIDPTMSRLLA
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHHHHHHH
ERGVDAAPHRSRRLSRALVRAADLVLVTERRQITEVEAIDPFARGKVHLLGKWEDAEIAD
HCCCCCCCHHHHHHHHHHHHHHHHHEECCCHHHHHHHHCCHHHCCCEEEEECCCCCCCCC
PHGGPEADYRESYTLIERLVQGWLQKIC
CCCCCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9434192; 9571056 [H]