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The map label for this gene is luxQ [H]

Identifier: 126444429

GI number: 126444429

Start: 174264

End: 176756

Strand: Reverse

Name: luxQ [H]

Synonym: BURPS668_A0191

Alternate gene names: 126444429

Gene position: 176756-174264 (Counterclockwise)

Preceding gene: 126445375

Following gene: 126444900

Centisome position: 5.65

GC content: 65.06

Gene sequence:

>2493_bases
ATGAACGATCCCCTGCGCGCCTGCTCGATCCTGCCCGCCGTCGAGGTTGAAGCCCGTCGGTCTGCTCGTGTACGCCGGTT
GCTTCACTGGACGGCTGGTCTGAGCATCGCGCTCGCGCCGTTTGCGGCGTTCCACGCACGCGCGGCCACGCTGTTCACCA
GCGAAGAGCAGCACTGGATCGACACGCATCCCGTCGTGCGTTTCGCGGCCGGCCCCGGCGCGCAGCCCTTCGACTACGTG
GAAGACGGCAAGCACCGCGGCCTTACCGCGGACTATCTCGACGCGCTCGCCCGCATCAGCGGGCTGGAGTTCGAGAGGGT
CGACACCACTCGCTGGGGCTCGCCGACCGCCGCGTTCGCCGCGCACGAAATCGACCTGCTGCCCAACGTCGCCTATGGTC
TGCAGAATGACGTCCTTCAACGCGAAGCGACCTTCAGCAGCCCTTATCTCGTCGGATCGGCGGTCATCGTGACACGCGAA
TCGCAGACCGTGATCTTCGATCTCGACAAGCTGTCCGGCCAAACCATCGCAGTGCGCTCGGGCGGCGCGTACGAACGCTT
TCTCCGTCAGCACCATCCGTCGATACGACTACTCTCGACCCTCGAGCAGCGCGATATGCTCGACGCGGTCGCGACGGGCC
GCGCAGACGCGGCGATCGGGCTCGACGCGATGCTCGTGCCCGCGATTCGCAGCAGTTATTCTCACCGCCTGTACATTTCA
GGCGCCGTCGCGAACATGCCCGCCGTGATCGTCATGGCCACGCGCAAAGACTTGCCGGTACTGGCGTCGATCATCGACAA
GTCGCTGAACTCGCTGACAGCGCGCGACGTCAACGAACTGACGACGCACTGGCTCTACAGCTCGGACTTCGGCGCGCCGT
CTTTGCGCGCGATCACGCACTACTACACGATTGAAATCGTCCTCGGCGTCTTCGTCGTGTCGGGCTTCGCGATGCTCGCC
TTCCGATCCCGTGCGCAGTATCGGTTGACGGCCGAGAGCGAAGCGCGCAAGTCGCGCTTCATCGCGGTGATGAGTCATGA
AATCCGCACGCCGCTCAACGCGATCGTATCGGCAATCGACCTGCTCAGCCGCGCGAAACTAGGGCCGATGGAGAAGCAGC
TCGCCGATACGGCGGTCAAGGCGTCCGCCAGTCTCGTCGGCATGCTCGACGACGTGCTGGACATTTCCAAGCTCCATGCG
AAAAAGCTGCGGCTCGCGCACGTCGCCAGCGACATCCGGACCGTTGCCGAGAGTGCCGTCATCATCATGCGCGCCCAGGC
CGACGCCAAGGGCTTGCCGCTCGAACTGCATCTCGACGCCCCCGACCATCTCGACGTGTACATCGATCAGACACGCATCC
GCCAGATTCTCGTCAACTTGCTGTCGAACGCAATCAAGTTCACGGACGCCGGGCGCGTGTGCGTCGACGTCAAACTGGCG
ATCGCCGATCCGCCGACGCACGCGCCCGGAGAACTGACGCTGAAGGTGAGCGACACCGGCATCGGCATTCCGAAGAACCG
GCAAGACCGCCTGTTCGACGCGTTCGAGCAGGCCGACTCGACGACGACGCGGCGCTTCGGCGGTACGGGCCTCGGTCTGA
CCATCTGCAAGGAACTCGTCGCATTGATGGGCGGCACGTTGGCGCTCGACAGCAAGGAACGCGTCGGCACCTCGGTAACG
GTAGTGATTCCGGTCGACACCGCGCAGCGCGAGGTATGCGCGCCCGTCGACCGGGACGCCGTCGCGGATTCGCCGTCCAA
CGCACGCGCTGACCGGCCGCGCGTGCTGGTGGTGGAAGACCAGCCGCTCAACGCGGAGCTGATCCGTCTTCAGCTTGCCG
AACTGCATTGCGACGCGACTATCGCGAACACCGGCCAAGCGGCGCTCGGTCTGCTGGATGATCAGGCGTTCGCGCTCGTG
CTGCTCGACTGCAATCTGCCCGACATCGACGGTTACGAAGTGGCGCGCCGCATTCGAGCAGCCCGGCGGAATGCAACGAC
CTATCTGCCGGTCATCGCCATTTCCGCACTGACGGACCATGCCCATCTGCATGAGTGCATCGCCGCGGGCATGGATGGAA
GTTTGCGCAAGCCGCTCATGCTCGACGATGTCGCGTCGATAATCGACTTGTGGTGCCGCGCCGCCGGAGTGGCCGACGGC
TCCGCCGGATCCCCCGGCTCATCGTCGCCCGCGGAACGGGACATCGATCTGCCTCGGCTGGCATCGCTATTCGCGACCAC
CTGCGCCGAGGATAGCGCGCTCATAGGCAGCGCCCTCGCACGCGGCGACTTCAAGCGAGCGGCGTCATGCGCGCATCGCA
TCAAAAGCGCCGCGCATGTGATGCGCCAGCATGACATCGCGCAAACCGCGGAACGGCTCGAGCGCGCGCTATCGGCTCCC
GATGTGAACGTCAACGCGGCGCGGCGCAACGCGGCAAAACTCGCCCGGCTCATCTCCGGCATTGCCCCGGATCGCCTCTC
GTTCGATGTCTGA

Upstream 100 bases:

>100_bases
GGAACACGAACGGCCACGTCGTGCGCGCGTTTATCATGCGGGCAAGCCAATCCTGTTGCGAACCGCCTGTTCCGTTGCGC
GTTCGCGATACCCGACAAAC

Downstream 100 bases:

>100_bases
AACATCTCATGCGCCGCGCAAGGCTCGCGCGCAATCATCGCAAGCGTGCCGCGCCTCCAAACGCGTCAGTTCGCGTACGG
ACTGCCCGCGTCGCCCGAAC

Product: sensor protein EvgS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 830; Mature: 830

Protein sequence:

>830_residues
MNDPLRACSILPAVEVEARRSARVRRLLHWTAGLSIALAPFAAFHARAATLFTSEEQHWIDTHPVVRFAAGPGAQPFDYV
EDGKHRGLTADYLDALARISGLEFERVDTTRWGSPTAAFAAHEIDLLPNVAYGLQNDVLQREATFSSPYLVGSAVIVTRE
SQTVIFDLDKLSGQTIAVRSGGAYERFLRQHHPSIRLLSTLEQRDMLDAVATGRADAAIGLDAMLVPAIRSSYSHRLYIS
GAVANMPAVIVMATRKDLPVLASIIDKSLNSLTARDVNELTTHWLYSSDFGAPSLRAITHYYTIEIVLGVFVVSGFAMLA
FRSRAQYRLTAESEARKSRFIAVMSHEIRTPLNAIVSAIDLLSRAKLGPMEKQLADTAVKASASLVGMLDDVLDISKLHA
KKLRLAHVASDIRTVAESAVIIMRAQADAKGLPLELHLDAPDHLDVYIDQTRIRQILVNLLSNAIKFTDAGRVCVDVKLA
IADPPTHAPGELTLKVSDTGIGIPKNRQDRLFDAFEQADSTTTRRFGGTGLGLTICKELVALMGGTLALDSKERVGTSVT
VVIPVDTAQREVCAPVDRDAVADSPSNARADRPRVLVVEDQPLNAELIRLQLAELHCDATIANTGQAALGLLDDQAFALV
LLDCNLPDIDGYEVARRIRAARRNATTYLPVIAISALTDHAHLHECIAAGMDGSLRKPLMLDDVASIIDLWCRAAGVADG
SAGSPGSSSPAERDIDLPRLASLFATTCAEDSALIGSALARGDFKRAASCAHRIKSAAHVMRQHDIAQTAERLERALSAP
DVNVNAARRNAAKLARLISGIAPDRLSFDV

Sequences:

>Translated_830_residues
MNDPLRACSILPAVEVEARRSARVRRLLHWTAGLSIALAPFAAFHARAATLFTSEEQHWIDTHPVVRFAAGPGAQPFDYV
EDGKHRGLTADYLDALARISGLEFERVDTTRWGSPTAAFAAHEIDLLPNVAYGLQNDVLQREATFSSPYLVGSAVIVTRE
SQTVIFDLDKLSGQTIAVRSGGAYERFLRQHHPSIRLLSTLEQRDMLDAVATGRADAAIGLDAMLVPAIRSSYSHRLYIS
GAVANMPAVIVMATRKDLPVLASIIDKSLNSLTARDVNELTTHWLYSSDFGAPSLRAITHYYTIEIVLGVFVVSGFAMLA
FRSRAQYRLTAESEARKSRFIAVMSHEIRTPLNAIVSAIDLLSRAKLGPMEKQLADTAVKASASLVGMLDDVLDISKLHA
KKLRLAHVASDIRTVAESAVIIMRAQADAKGLPLELHLDAPDHLDVYIDQTRIRQILVNLLSNAIKFTDAGRVCVDVKLA
IADPPTHAPGELTLKVSDTGIGIPKNRQDRLFDAFEQADSTTTRRFGGTGLGLTICKELVALMGGTLALDSKERVGTSVT
VVIPVDTAQREVCAPVDRDAVADSPSNARADRPRVLVVEDQPLNAELIRLQLAELHCDATIANTGQAALGLLDDQAFALV
LLDCNLPDIDGYEVARRIRAARRNATTYLPVIAISALTDHAHLHECIAAGMDGSLRKPLMLDDVASIIDLWCRAAGVADG
SAGSPGSSSPAERDIDLPRLASLFATTCAEDSALIGSALARGDFKRAASCAHRIKSAAHVMRQHDIAQTAERLERALSAP
DVNVNAARRNAAKLARLISGIAPDRLSFDV
>Mature_830_residues
MNDPLRACSILPAVEVEARRSARVRRLLHWTAGLSIALAPFAAFHARAATLFTSEEQHWIDTHPVVRFAAGPGAQPFDYV
EDGKHRGLTADYLDALARISGLEFERVDTTRWGSPTAAFAAHEIDLLPNVAYGLQNDVLQREATFSSPYLVGSAVIVTRE
SQTVIFDLDKLSGQTIAVRSGGAYERFLRQHHPSIRLLSTLEQRDMLDAVATGRADAAIGLDAMLVPAIRSSYSHRLYIS
GAVANMPAVIVMATRKDLPVLASIIDKSLNSLTARDVNELTTHWLYSSDFGAPSLRAITHYYTIEIVLGVFVVSGFAMLA
FRSRAQYRLTAESEARKSRFIAVMSHEIRTPLNAIVSAIDLLSRAKLGPMEKQLADTAVKASASLVGMLDDVLDISKLHA
KKLRLAHVASDIRTVAESAVIIMRAQADAKGLPLELHLDAPDHLDVYIDQTRIRQILVNLLSNAIKFTDAGRVCVDVKLA
IADPPTHAPGELTLKVSDTGIGIPKNRQDRLFDAFEQADSTTTRRFGGTGLGLTICKELVALMGGTLALDSKERVGTSVT
VVIPVDTAQREVCAPVDRDAVADSPSNARADRPRVLVVEDQPLNAELIRLQLAELHCDATIANTGQAALGLLDDQAFALV
LLDCNLPDIDGYEVARRIRAARRNATTYLPVIAISALTDHAHLHECIAAGMDGSLRKPLMLDDVASIIDLWCRAAGVADG
SAGSPGSSSPAERDIDLPRLASLFATTCAEDSALIGSALARGDFKRAASCAHRIKSAAHVMRQHDIAQTAERLERALSAP
DVNVNAARRNAAKLARLISGIAPDRLSFDV

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=473, Percent_Identity=30.4439746300211, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI48994928, Length=498, Percent_Identity=30.3212851405622, Blast_Score=183, Evalue=5e-47,
Organism=Escherichia coli, GI1789149, Length=240, Percent_Identity=39.1666666666667, Blast_Score=162, Evalue=8e-41,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=36.4754098360656, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI87081816, Length=503, Percent_Identity=29.0258449304175, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1786912, Length=251, Percent_Identity=26.2948207171315, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1788393, Length=245, Percent_Identity=26.530612244898, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=271, Percent_Identity=25.830258302583, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=285, Percent_Identity=25.2631578947368, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1786783, Length=238, Percent_Identity=28.1512605042017, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1788549, Length=267, Percent_Identity=22.8464419475655, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790861, Length=233, Percent_Identity=25.7510729613734, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87082128, Length=221, Percent_Identity=25.3393665158371, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=90, Percent_Identity=40, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 89644; Mature: 89644

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDPLRACSILPAVEVEARRSARVRRLLHWTAGLSIALAPFAAFHARAATLFTSEEQHWI
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCCC
DTHPVVRFAAGPGAQPFDYVEDGKHRGLTADYLDALARISGLEFERVDTTRWGSPTAAFA
CCCCEEEEECCCCCCCCCHHHCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCHHHH
AHEIDLLPNVAYGLQNDVLQREATFSSPYLVGSAVIVTRESQTVIFDLDKLSGQTIAVRS
HHHHHHCCHHHHHHHHHHHHHHHCCCCCEEECEEEEEEECCCEEEEEECCCCCCEEEEEC
GGAYERFLRQHHPSIRLLSTLEQRDMLDAVATGRADAAIGLDAMLVPAIRSSYSHRLYIS
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHCCCCCEEEEE
GAVANMPAVIVMATRKDLPVLASIIDKSLNSLTARDVNELTTHWLYSSDFGAPSLRAITH
ECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHH
YYTIEIVLGVFVVSGFAMLAFRSRAQYRLTAESEARKSRFIAVMSHEIRTPLNAIVSAID
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LLSRAKLGPMEKQLADTAVKASASLVGMLDDVLDISKLHAKKLRLAHVASDIRTVAESAV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEE
IIMRAQADAKGLPLELHLDAPDHLDVYIDQTRIRQILVNLLSNAIKFTDAGRVCVDVKLA
EEEEECCCCCCCCEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHEECCCCCEEEEEEEE
IADPPTHAPGELTLKVSDTGIGIPKNRQDRLFDAFEQADSTTTRRFGGTGLGLTICKELV
EECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHH
ALMGGTLALDSKERVGTSVTVVIPVDTAQREVCAPVDRDAVADSPSNARADRPRVLVVED
HHHCCCEEECCHHHCCCEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEC
QPLNAELIRLQLAELHCDATIANTGQAALGLLDDQAFALVLLDCNLPDIDGYEVARRIRA
CCCCHHHHHHHHHHHHCCCEECCCCCHHHEEECCCCEEEEEEECCCCCCCHHHHHHHHHH
ARRNATTYLPVIAISALTDHAHLHECIAAGMDGSLRKPLMLDDVASIIDLWCRAAGVADG
HHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
SAGSPGSSSPAERDIDLPRLASLFATTCAEDSALIGSALARGDFKRAASCAHRIKSAAHV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRQHDIAQTAERLERALSAPDVNVNAARRNAAKLARLISGIAPDRLSFDV
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNDPLRACSILPAVEVEARRSARVRRLLHWTAGLSIALAPFAAFHARAATLFTSEEQHWI
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCCCCC
DTHPVVRFAAGPGAQPFDYVEDGKHRGLTADYLDALARISGLEFERVDTTRWGSPTAAFA
CCCCEEEEECCCCCCCCCHHHCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCHHHH
AHEIDLLPNVAYGLQNDVLQREATFSSPYLVGSAVIVTRESQTVIFDLDKLSGQTIAVRS
HHHHHHCCHHHHHHHHHHHHHHHCCCCCEEECEEEEEEECCCEEEEEECCCCCCEEEEEC
GGAYERFLRQHHPSIRLLSTLEQRDMLDAVATGRADAAIGLDAMLVPAIRSSYSHRLYIS
CCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCHHHHHHHHHHCCCCCEEEEE
GAVANMPAVIVMATRKDLPVLASIIDKSLNSLTARDVNELTTHWLYSSDFGAPSLRAITH
ECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHH
YYTIEIVLGVFVVSGFAMLAFRSRAQYRLTAESEARKSRFIAVMSHEIRTPLNAIVSAID
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LLSRAKLGPMEKQLADTAVKASASLVGMLDDVLDISKLHAKKLRLAHVASDIRTVAESAV
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEE
IIMRAQADAKGLPLELHLDAPDHLDVYIDQTRIRQILVNLLSNAIKFTDAGRVCVDVKLA
EEEEECCCCCCCCEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHEECCCCCEEEEEEEE
IADPPTHAPGELTLKVSDTGIGIPKNRQDRLFDAFEQADSTTTRRFGGTGLGLTICKELV
EECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHH
ALMGGTLALDSKERVGTSVTVVIPVDTAQREVCAPVDRDAVADSPSNARADRPRVLVVED
HHHCCCEEECCHHHCCCEEEEEEECCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEC
QPLNAELIRLQLAELHCDATIANTGQAALGLLDDQAFALVLLDCNLPDIDGYEVARRIRA
CCCCHHHHHHHHHHHHCCCEECCCCCHHHEEECCCCEEEEEEECCCCCCCHHHHHHHHHH
ARRNATTYLPVIAISALTDHAHLHECIAAGMDGSLRKPLMLDDVASIIDLWCRAAGVADG
HHCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
SAGSPGSSSPAERDIDLPRLASLFATTCAEDSALIGSALARGDFKRAASCAHRIKSAAHV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MRQHDIAQTAERLERALSAPDVNVNAARRNAAKLARLISGIAPDRLSFDV
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA