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The map label for this gene is yyaJ [H]

Identifier: 126444242

GI number: 126444242

Start: 2008056

End: 2009474

Strand: Reverse

Name: yyaJ [H]

Synonym: BURPS668_A2070

Alternate gene names: 126444242

Gene position: 2009474-2008056 (Counterclockwise)

Preceding gene: 126442912

Following gene: 126444999

Centisome position: 64.25

GC content: 68.43

Gene sequence:

>1419_bases
ATGGCTTCAACGCAAAGCGCGCCGCGCGCAACGGCGCCGGCAACGACGATCGACGCCGGCGTCATCTCGGCGCGCCTCGA
TCGCCTGCCGCCCACGCGCAGCGTCTGGAAACTCGTCGCGCTGCTGAGTCTCGGCTTCTTCTTCGAGCTCTACGATCTGC
TGTACAGCGGCTACGTCGCGCCCGGCCTCGTGAAGGGCGGCATCCTGAGCGCGACGACGCGCGGGCTGTTCGGCACGACG
GGCGTCGCGAGCTTCATCGCCGCGCTGTTCGCGGGGCTCTTCATCGGCACGATCGCGTGCGGCTTTCTCGCCGACCGCTT
CGGCCGCCGCGCGGTGTTTACGTGGTCGCTGCTGTGGTACACGGCCGCGAACCTCGTGATGGCGTTCCAGGATACCGCCG
GGGGCCTCAATTTCTGGCGCTTCGTCGTCGGGCTGGGGCTCGGCGTCGAAATGGTGACGATCGGCACATATATCTCGGAG
TTGGTCCCGAAACAGATTCGCGGCCGCGCGTTCGCGTGCGAGCAGGCGGTCGGCTTCGTCGCGGTGCCCGTGGTGGCGCT
GCTCGCGTATCTGCTGGTGCCGCATGCGCCGTTCGGCCTCGACGGCTGGCGCTGGGTCGTGCTGATCGGCGCGCACGGCG
CGATCTTCGTCTGGTGGATTCGCCGCCAGTTGCCGGAAAGCCCGCGCTGGCTCGCGCAGCAGGGCCGGCTTGACGAAGCC
GAGCGCGTGCTCGCCGCGCTCGAGGCGAAGGTCGAGGCCGAGTACGGCCGGCCGCTGCCGCCGCCCGCGCCCGCCGAGCC
CATCGCGCCGCGCGGCCGGTTCGCCGACATGTGGGTGCCGCCGTACCGCAGGCGCACGGTGATGATGACGATCTTCAACG
TGTTTCAGACGGTGGGCTTCTACGGCTTCGCGAACTGGGTGCCGACGCTGCTGATCAAGCAGGGGATCACCGTCACGACG
AGCCTCATGTATTCGAGCGTGATCGCGCTCGCCGCGCCGATCGGGCCGTTGATCGGCCTTGCGATCGCCGACCGCTTCGA
GCGCAAGACGGTGATCGTCGCGATGGCGGGCGCGGCGATGATCGCGGGGCTGCTGTTCAGCCACGCGTCGGCCGCGTGGC
TGCTCGTCGCGCTCGGCGTATGCCTCACGCTCGCGAACAACATCATGTCGTACAGCTTCCATGCCTATCAGGCCGAGCTG
TTTCCGACCGCGATCCGCGCGCGCGCGGTCGGCTTCGTCTATTCGTGGAGCCGCTTTTCGGCGATCTTCACGTCGTTCGC
GATCGCGGCCGTGCTGAAGGGATTCGGCACGCCCGGCGTGTTCGTGTTCATCGCGGGCGCGATGGCGATCGTGATGGCGT
CGATCGGGCTGATGGGGCCGCGCACGAAAGGCGTCGCGCTCGAAGCGATATCGCGTTGA

Upstream 100 bases:

>100_bases
CGTGATGCTCGACGCGGCGCGCGGCCGGTAAAATGCCCGAACCCCGGCGGCCACGCGCGGCCGCCGTCAGACGACAACGA
CATTCGGAGACACTTCGGCC

Downstream 100 bases:

>100_bases
CGCGTGCGCGCGCGCTCGCGTGCGCGGGATACCGGCACGCAGGGCGTCGCGCGCCGCGCAACGGGCTTGAGCACTGCCGG
GCGGCGCATGTGTGGGCGGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MASTQSAPRATAPATTIDAGVISARLDRLPPTRSVWKLVALLSLGFFFELYDLLYSGYVAPGLVKGGILSATTRGLFGTT
GVASFIAALFAGLFIGTIACGFLADRFGRRAVFTWSLLWYTAANLVMAFQDTAGGLNFWRFVVGLGLGVEMVTIGTYISE
LVPKQIRGRAFACEQAVGFVAVPVVALLAYLLVPHAPFGLDGWRWVVLIGAHGAIFVWWIRRQLPESPRWLAQQGRLDEA
ERVLAALEAKVEAEYGRPLPPPAPAEPIAPRGRFADMWVPPYRRRTVMMTIFNVFQTVGFYGFANWVPTLLIKQGITVTT
SLMYSSVIALAAPIGPLIGLAIADRFERKTVIVAMAGAAMIAGLLFSHASAAWLLVALGVCLTLANNIMSYSFHAYQAEL
FPTAIRARAVGFVYSWSRFSAIFTSFAIAAVLKGFGTPGVFVFIAGAMAIVMASIGLMGPRTKGVALEAISR

Sequences:

>Translated_472_residues
MASTQSAPRATAPATTIDAGVISARLDRLPPTRSVWKLVALLSLGFFFELYDLLYSGYVAPGLVKGGILSATTRGLFGTT
GVASFIAALFAGLFIGTIACGFLADRFGRRAVFTWSLLWYTAANLVMAFQDTAGGLNFWRFVVGLGLGVEMVTIGTYISE
LVPKQIRGRAFACEQAVGFVAVPVVALLAYLLVPHAPFGLDGWRWVVLIGAHGAIFVWWIRRQLPESPRWLAQQGRLDEA
ERVLAALEAKVEAEYGRPLPPPAPAEPIAPRGRFADMWVPPYRRRTVMMTIFNVFQTVGFYGFANWVPTLLIKQGITVTT
SLMYSSVIALAAPIGPLIGLAIADRFERKTVIVAMAGAAMIAGLLFSHASAAWLLVALGVCLTLANNIMSYSFHAYQAEL
FPTAIRARAVGFVYSWSRFSAIFTSFAIAAVLKGFGTPGVFVFIAGAMAIVMASIGLMGPRTKGVALEAISR
>Mature_471_residues
ASTQSAPRATAPATTIDAGVISARLDRLPPTRSVWKLVALLSLGFFFELYDLLYSGYVAPGLVKGGILSATTRGLFGTTG
VASFIAALFAGLFIGTIACGFLADRFGRRAVFTWSLLWYTAANLVMAFQDTAGGLNFWRFVVGLGLGVEMVTIGTYISEL
VPKQIRGRAFACEQAVGFVAVPVVALLAYLLVPHAPFGLDGWRWVVLIGAHGAIFVWWIRRQLPESPRWLAQQGRLDEAE
RVLAALEAKVEAEYGRPLPPPAPAEPIAPRGRFADMWVPPYRRRTVMMTIFNVFQTVGFYGFANWVPTLLIKQGITVTTS
LMYSSVIALAAPIGPLIGLAIADRFERKTVIVAMAGAAMIAGLLFSHASAAWLLVALGVCLTLANNIMSYSFHAYQAELF
PTAIRARAVGFVYSWSRFSAIFTSFAIAAVLKGFGTPGVFVFIAGAMAIVMASIGLMGPRTKGVALEAISR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI166064021, Length=464, Percent_Identity=25.4310344827586, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI302148518, Length=403, Percent_Identity=26.7990074441687, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI4506999, Length=403, Percent_Identity=26.7990074441687, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI203098995, Length=272, Percent_Identity=27.2058823529412, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI216548223, Length=318, Percent_Identity=23.2704402515723, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI213021148, Length=421, Percent_Identity=24.7030878859857, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI23510410, Length=339, Percent_Identity=27.1386430678466, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI24308167, Length=469, Percent_Identity=22.3880597014925, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI4507005, Length=400, Percent_Identity=24.5, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI7662270, Length=325, Percent_Identity=21.2307692307692, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI24497490, Length=388, Percent_Identity=22.9381443298969, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI24497497, Length=346, Percent_Identity=28.3236994219653, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1788068, Length=459, Percent_Identity=28.322440087146, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1788074, Length=457, Percent_Identity=29.9781181619256, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI87082159, Length=418, Percent_Identity=26.555023923445, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786229, Length=448, Percent_Identity=24.5535714285714, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789312, Length=267, Percent_Identity=27.3408239700375, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87082231, Length=206, Percent_Identity=29.126213592233, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1789207, Length=405, Percent_Identity=24.9382716049383, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790463, Length=436, Percent_Identity=23.1651376146789, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082404, Length=210, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71989531, Length=388, Percent_Identity=26.2886597938144, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71989525, Length=388, Percent_Identity=26.2886597938144, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25145172, Length=412, Percent_Identity=24.2718446601942, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319718, Length=304, Percent_Identity=26.9736842105263, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI19922616, Length=403, Percent_Identity=23.5732009925558, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24649618, Length=364, Percent_Identity=23.9010989010989, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640198, Length=474, Percent_Identity=20.6751054852321, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640196, Length=474, Percent_Identity=20.6751054852321, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24640200, Length=474, Percent_Identity=20.6751054852321, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 50833; Mature: 50702

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTQSAPRATAPATTIDAGVISARLDRLPPTRSVWKLVALLSLGFFFELYDLLYSGYVA
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PGLVKGGILSATTRGLFGTTGVASFIAALFAGLFIGTIACGFLADRFGRRAVFTWSLLWY
CHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
TAANLVMAFQDTAGGLNFWRFVVGLGLGVEMVTIGTYISELVPKQIRGRAFACEQAVGFV
HHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AVPVVALLAYLLVPHAPFGLDGWRWVVLIGAHGAIFVWWIRRQLPESPRWLAQQGRLDEA
HHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHHHCCCCCHH
ERVLAALEAKVEAEYGRPLPPPAPAEPIAPRGRFADMWVPPYRRRTVMMTIFNVFQTVGF
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
YGFANWVPTLLIKQGITVTTSLMYSSVIALAAPIGPLIGLAIADRFERKTVIVAMAGAAM
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHH
IAGLLFSHASAAWLLVALGVCLTLANNIMSYSFHAYQAELFPTAIRARAVGFVYSWSRFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIFTSFAIAAVLKGFGTPGVFVFIAGAMAIVMASIGLMGPRTKGVALEAISR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCC
>Mature Secondary Structure 
ASTQSAPRATAPATTIDAGVISARLDRLPPTRSVWKLVALLSLGFFFELYDLLYSGYVA
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC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HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]