Click here to switch to the map view.

The map label for this gene is sciM [H]

Identifier: 126444160

GI number: 126444160

Start: 297541

End: 298026

Strand: Reverse

Name: sciM [H]

Synonym: BURPS668_A0331

Alternate gene names: 126444160

Gene position: 298026-297541 (Counterclockwise)

Preceding gene: 126445449

Following gene: 126443853

Centisome position: 9.53

GC content: 62.96

Gene sequence:

>486_bases
ATGGCGCAGGATATTTTTCTGAAGATCGACGGCATCAACGGTGAATCCCTCGACGACAGCCACAAGGACGAGATCGAAGT
CCTGAACTGGAACTGGGAGATTCAGCAGGAATCGACGATGCACACGGGCAGCGGCGGCGGCGCCGGCAAGGCGAGCGTGA
AGGATCTGACGTTCGAGCACGCGATCGACCGCGCGAGCCCCAACCTGATGAAGTACGCGCTGACCGGCAAGCACGTCGAT
CAGGCGGTGCTCGTGATGCGCAAGGCGGGCGGCAATCCGCTCGAATACCTGAAGCTCACGATGAGCGACGTGATCATCAC
GCGCGTGCGGCCGTCGGGCAGCCGCGACGACACCGAGCGCAGCCGCGAGACGGTATCGCTGTCGTTCGCGAAGGTGAAGC
AGGAGTATGTCGTGCAGAACGCGCAGGGCGGCAGCGGCGGCGCCGTCACGACGAGCTTCGACATCAAGGGCAACAAGGAA
GCCTGA

Upstream 100 bases:

>100_bases
CGTCCCCGGTCGGCCGGCTTCGCGCCTTCGCCCACGCGCGCGACGCCGCGCGGGGCCGGCTGTTTTGTCATCCACGCAAT
CCACGTAAGAGAGCAATGAA

Downstream 100 bases:

>100_bases
GCGGCGCCCGCGCGGGGCCCGCCGAGCGGCGCGCGGCAGAGCGCCGTTCGCCGGGCCCGCGCCGCCCTCGGCCGGTTCTC
CCCCTCACACCCAACGCGTG

Product: SciM protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MAQDIFLKIDGINGESLDDSHKDEIEVLNWNWEIQQESTMHTGSGGGAGKASVKDLTFEHAIDRASPNLMKYALTGKHVD
QAVLVMRKAGGNPLEYLKLTMSDVIITRVRPSGSRDDTERSRETVSLSFAKVKQEYVVQNAQGGSGGAVTTSFDIKGNKE
A

Sequences:

>Translated_161_residues
MAQDIFLKIDGINGESLDDSHKDEIEVLNWNWEIQQESTMHTGSGGGAGKASVKDLTFEHAIDRASPNLMKYALTGKHVD
QAVLVMRKAGGNPLEYLKLTMSDVIITRVRPSGSRDDTERSRETVSLSFAKVKQEYVVQNAQGGSGGAVTTSFDIKGNKE
A
>Mature_160_residues
AQDIFLKIDGINGESLDDSHKDEIEVLNWNWEIQQESTMHTGSGGGAGKASVKDLTFEHAIDRASPNLMKYALTGKHVDQ
AVLVMRKAGGNPLEYLKLTMSDVIITRVRPSGSRDDTERSRETVSLSFAKVKQEYVVQNAQGGSGGAVTTSFDIKGNKEA

Specific function: Required for assembly of the protein secretion apparatus HSI-I. Actively secreted during chronic infection of cystic fibrosis patients [H]

COG id: COG3157

COG function: function code S; Hemolysin-coregulated protein (uncharacterized)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hcp1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017728
- InterPro:   IPR008514 [H]

Pfam domain/function: PF05638 DUF796 [H]

EC number: NA

Molecular weight: Translated: 17542; Mature: 17411

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQDIFLKIDGINGESLDDSHKDEIEVLNWNWEIQQESTMHTGSGGGAGKASVKDLTFEH
CCCEEEEEEECCCCCCCCCCCCCCEEEEECCEEECCCCEEECCCCCCCCCCCHHHHHHHH
AIDRASPNLMKYALTGKHVDQAVLVMRKAGGNPLEYLKLTMSDVIITRVRPSGSRDDTER
HHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHEEEEEECCCCCCCCCHH
SRETVSLSFAKVKQEYVVQNAQGGSGGAVTTSFDIKGNKEA
HHHEEEHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
AQDIFLKIDGINGESLDDSHKDEIEVLNWNWEIQQESTMHTGSGGGAGKASVKDLTFEH
CCEEEEEEECCCCCCCCCCCCCCEEEEECCEEECCCCEEECCCCCCCCCCCHHHHHHHH
AIDRASPNLMKYALTGKHVDQAVLVMRKAGGNPLEYLKLTMSDVIITRVRPSGSRDDTER
HHCCCCCCEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHEEEEEECCCCCCCCCHH
SRETVSLSFAKVKQEYVVQNAQGGSGGAVTTSFDIKGNKEA
HHHEEEHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]