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The map label for this gene is acoR [H]

Identifier: 126444130

GI number: 126444130

Start: 873539

End: 875479

Strand: Reverse

Name: acoR [H]

Synonym: BURPS668_A0890

Alternate gene names: 126444130

Gene position: 875479-873539 (Counterclockwise)

Preceding gene: 126443785

Following gene: 126445549

Centisome position: 27.99

GC content: 71.56

Gene sequence:

>1941_bases
ATGCCGCAATCTTCCGTGCTGCCCGCCGCGGCGGGCCGCGTCGACCTGCTCGCGCAAGCGCACGCCCGCTCGCTGTCGGT
CGGCCTGCGCGCGTCCGAGCTGCCCGATTTCTCGCCGCTGTCGCGCGCCGCGCTGCGCGAGCTGATCGACGGCAGCCCAT
CGCTGTACACGCACGCGCGCCCGGTGATGGACACGCTGCACACGCAGATCGCCGATACGCAAAGCCTCGTGCTGCTGACC
GACCGCGACGGCGTGATCCTGCACAGCATCGGCGACGCCGATTTCGTCGAAAAGGCGAACCGGGTCGCGCTCTGCCCCGG
CGTGTCATGGGCGGAAGACGCGCGGGGCACGAATGCGATCGGCACCGCGCTGATCGCGGGCCAGGCGCTCGCCGTGCACG
GCACCGAGCATTTCCTGCGCGCGAATCACGTGCTCACCTGCTCGTGCGCGCCGATCGTCGATCCGTTCGGCCGCCTCCTC
GGCGCGCTCGACGTGAGCGGCGATCCGCGCGGCTTCAGCCCGCATACGCTCGCGCTCGTGAAGATGTCCGCGCAACTGAT
CGAAAACCATCTGTTCGCGAATCAGTGCGCGGACGCGCTGCGCGTGCGCTTTCACGCGCACGACGAATTCGTCGATTCGC
TGTTCGCCGGCCTCGTCGCGTTCAGCCCGAGCGGTGCGCTGATCGCGGCCAATCGCAGCGCACAATTCCAGCTCGGCGCG
AATCTCGATGCACTGCAACAGCGCGGTTGCGACGAACTGTTCGGCCTGTCTTTCGCGAAGCTCGCGCAGCATGCGGCGCG
CGAACCGCTCGCGTGCTTCACGCTGACGCTCGGCACCGGCGTGCGCGTGCGCGCGCGCTGCGAATTCGCGCACGCGCAGC
GCACGGCCGTTGCGGTGAGCGCGCGCGCCGCGCCGACGCGCGCAACCGATGCGGCGCGCGACGAGGAGCCCGACGCGATC
ACGTTCGCGACGCTCGATACGGGCGATGCGCGCATGACCGCCGTGCTGCAGCGGGTCGGCAAGGTGCGCGGGCGCGACCT
GCCGGTGCTCGTGCTCGGCGAAACCGGCACCGGCAAGGAATGGCTCGCGCGCGCGCTGCACCACGCGTCGCCGCGCCGCG
ACGGCCCGTTCGTCGCGGTCAACTGCGCGGCGCTGCCCGATTCGCTGATCGAAGCGGAACTATTCGGCTACGAGGACGGC
GCGTTCACCGGCGCGCGCAAGCGCGGCAGCCCCGGCAAGATCGCGCAGGCGGACGGCGGCACGCTGTTTCTCGACGAAAT
CGGCGACATGCCGCTCGCACAGCAGGTCCGGCTGATGCGCGTGCTGCAGGAGCGCGCGGTGATGCCGCTCGGCGGCGCGC
GCGCGGTGCCGGTGGACGTGCGGATCGTCTGCGCGACGCACCGCGACCTGCGCGCGATGATCGCCGCCGGCACGTTTCGC
GAGGATCTGTTCTACCGGATCAACGGCCTGGCGGTCACGCTGCCGCCGCTTGCCGAGCGCTCGGATCTCGAGACGCTCGT
CGCCCGCGTGCTCGCGCGGCTCGCGCGCAGCGAGCCGATGCCGGCCACCGTGTCGGCGGCGGTGCTCGCCGCGTTCGCGC
GCTGCCGGTGGCCGGGCAATCTGCGTCAAATGACGAACGTGCTGCGCACGGCGGGCATGCTCGCCGAAGGCGAAGCGCGG
ATCGACGTCGCGCATCTGCCTGACGATTTCTGGCTCGACTGCGACGCGCGCGCGCGCGATGCGACACCGCCGCGCACGTG
TGCCGACGCGGCGGCGGGCGCGGCAGCGGCCGGCGCCTCGACGCTGCAGGATCATCAGGTCGCGCTGATCGACGGCGCGC
TCGACCGGCATCGCGGCAACGTATCGGCGGCCGCGCGCGAGCTCGGGCTCGCGCGCAATACCGTCTATCGGCATTTGCGT
AGACGGCGGTCGAGGGAGTGA

Upstream 100 bases:

>100_bases
GCGGCGCTTGTATGATGGGACGTGCCCGCGCCGCCACGTCCACCGCTGCGCCGGTCGAGCGGAGAACGCACTCCGCCGGC
GGGCCTCCTGGAGACAAGTC

Downstream 100 bases:

>100_bases
TCGGCGCGGTTGGCGGTCGGCGGTCGGCGGTCGGCGGTCGGCGGTCGGCGGTCGGCGGTCGGCGGTCGGCGGCTATCAAC
TATCGACTGCCGACGGGCGG

Product: sigma-54 dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 646; Mature: 645

Protein sequence:

>646_residues
MPQSSVLPAAAGRVDLLAQAHARSLSVGLRASELPDFSPLSRAALRELIDGSPSLYTHARPVMDTLHTQIADTQSLVLLT
DRDGVILHSIGDADFVEKANRVALCPGVSWAEDARGTNAIGTALIAGQALAVHGTEHFLRANHVLTCSCAPIVDPFGRLL
GALDVSGDPRGFSPHTLALVKMSAQLIENHLFANQCADALRVRFHAHDEFVDSLFAGLVAFSPSGALIAANRSAQFQLGA
NLDALQQRGCDELFGLSFAKLAQHAAREPLACFTLTLGTGVRVRARCEFAHAQRTAVAVSARAAPTRATDAARDEEPDAI
TFATLDTGDARMTAVLQRVGKVRGRDLPVLVLGETGTGKEWLARALHHASPRRDGPFVAVNCAALPDSLIEAELFGYEDG
AFTGARKRGSPGKIAQADGGTLFLDEIGDMPLAQQVRLMRVLQERAVMPLGGARAVPVDVRIVCATHRDLRAMIAAGTFR
EDLFYRINGLAVTLPPLAERSDLETLVARVLARLARSEPMPATVSAAVLAAFARCRWPGNLRQMTNVLRTAGMLAEGEAR
IDVAHLPDDFWLDCDARARDATPPRTCADAAAGAAAAGASTLQDHQVALIDGALDRHRGNVSAAARELGLARNTVYRHLR
RRRSRE

Sequences:

>Translated_646_residues
MPQSSVLPAAAGRVDLLAQAHARSLSVGLRASELPDFSPLSRAALRELIDGSPSLYTHARPVMDTLHTQIADTQSLVLLT
DRDGVILHSIGDADFVEKANRVALCPGVSWAEDARGTNAIGTALIAGQALAVHGTEHFLRANHVLTCSCAPIVDPFGRLL
GALDVSGDPRGFSPHTLALVKMSAQLIENHLFANQCADALRVRFHAHDEFVDSLFAGLVAFSPSGALIAANRSAQFQLGA
NLDALQQRGCDELFGLSFAKLAQHAAREPLACFTLTLGTGVRVRARCEFAHAQRTAVAVSARAAPTRATDAARDEEPDAI
TFATLDTGDARMTAVLQRVGKVRGRDLPVLVLGETGTGKEWLARALHHASPRRDGPFVAVNCAALPDSLIEAELFGYEDG
AFTGARKRGSPGKIAQADGGTLFLDEIGDMPLAQQVRLMRVLQERAVMPLGGARAVPVDVRIVCATHRDLRAMIAAGTFR
EDLFYRINGLAVTLPPLAERSDLETLVARVLARLARSEPMPATVSAAVLAAFARCRWPGNLRQMTNVLRTAGMLAEGEAR
IDVAHLPDDFWLDCDARARDATPPRTCADAAAGAAAAGASTLQDHQVALIDGALDRHRGNVSAAARELGLARNTVYRHLR
RRRSRE
>Mature_645_residues
PQSSVLPAAAGRVDLLAQAHARSLSVGLRASELPDFSPLSRAALRELIDGSPSLYTHARPVMDTLHTQIADTQSLVLLTD
RDGVILHSIGDADFVEKANRVALCPGVSWAEDARGTNAIGTALIAGQALAVHGTEHFLRANHVLTCSCAPIVDPFGRLLG
ALDVSGDPRGFSPHTLALVKMSAQLIENHLFANQCADALRVRFHAHDEFVDSLFAGLVAFSPSGALIAANRSAQFQLGAN
LDALQQRGCDELFGLSFAKLAQHAAREPLACFTLTLGTGVRVRARCEFAHAQRTAVAVSARAAPTRATDAARDEEPDAIT
FATLDTGDARMTAVLQRVGKVRGRDLPVLVLGETGTGKEWLARALHHASPRRDGPFVAVNCAALPDSLIEAELFGYEDGA
FTGARKRGSPGKIAQADGGTLFLDEIGDMPLAQQVRLMRVLQERAVMPLGGARAVPVDVRIVCATHRDLRAMIAAGTFRE
DLFYRINGLAVTLPPLAERSDLETLVARVLARLARSEPMPATVSAAVLAAFARCRWPGNLRQMTNVLRTAGMLAEGEARI
DVAHLPDDFWLDCDARARDATPPRTCADAAAGAAAAGASTLQDHQVALIDGALDRHRGNVSAAARELGLARNTVYRHLRR
RRSRE

Specific function: Required for sigma-54-dependent transcription of acoXABC [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1789233, Length=322, Percent_Identity=40.6832298136646, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI1790299, Length=323, Percent_Identity=41.7956656346749, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87082117, Length=232, Percent_Identity=48.7068965517241, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1788905, Length=320, Percent_Identity=39.6875, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1788550, Length=323, Percent_Identity=38.0804953560372, Blast_Score=213, Evalue=4e-56,
Organism=Escherichia coli, GI1790437, Length=318, Percent_Identity=38.9937106918239, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1789087, Length=318, Percent_Identity=39.937106918239, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1786524, Length=309, Percent_Identity=40.1294498381877, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI87081872, Length=309, Percent_Identity=38.1877022653722, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI87082152, Length=229, Percent_Identity=46.2882096069869, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1787583, Length=254, Percent_Identity=37.4015748031496, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI87081858, Length=586, Percent_Identity=25.0853242320819, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1789828, Length=247, Percent_Identity=37.246963562753, Blast_Score=135, Evalue=1e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 69006; Mature: 68875

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQSSVLPAAAGRVDLLAQAHARSLSVGLRASELPDFSPLSRAALRELIDGSPSLYTHAR
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHCCCCCHHHHHH
PVMDTLHTQIADTQSLVLLTDRDGVILHSIGDADFVEKANRVALCPGVSWAEDARGTNAI
HHHHHHHHHHCCCCEEEEEECCCCEEEEECCCHHHHHHCCCEEECCCCCCHHHCCCCCHH
GTALIAGQALAVHGTEHFLRANHVLTCSCAPIVDPFGRLLGALDVSGDPRGFSPHTLALV
HHHHHHCCEEEEECHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
KMSAQLIENHLFANQCADALRVRFHAHDEFVDSLFAGLVAFSPSGALIAANRSAQFQLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEECC
NLDALQQRGCDELFGLSFAKLAQHAAREPLACFTLTLGTGVRVRARCEFAHAQRTAVAVS
CHHHHHHCCCHHHHCCHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEHHHHHHHHEEEEE
ARAAPTRATDAARDEEPDAITFATLDTGDARMTAVLQRVGKVRGRDLPVLVLGETGTGKE
CCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCHH
WLARALHHASPRRDGPFVAVNCAALPDSLIEAELFGYEDGAFTGARKRGSPGKIAQADGG
HHHHHHHHCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCC
TLFLDEIGDMPLAQQVRLMRVLQERAVMPLGGARAVPVDVRIVCATHRDLRAMIAAGTFR
EEEHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEECCEEEEEEEECCHHHHHHHHHCCHH
EDLFYRINGLAVTLPPLAERSDLETLVARVLARLARSEPMPATVSAAVLAAFARCRWPGN
HHHHEEECCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
LRQMTNVLRTAGMLAEGEARIDVAHLPDDFWLDCDARARDATPPRTCADAAAGAAAAGAS
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCEECCCCCCCCCCCCHHHHHHHCCHHHCCCC
TLQDHQVALIDGALDRHRGNVSAAARELGLARNTVYRHLRRRRSRE
HHCCCEEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PQSSVLPAAAGRVDLLAQAHARSLSVGLRASELPDFSPLSRAALRELIDGSPSLYTHAR
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHCCCCCHHHHHH
PVMDTLHTQIADTQSLVLLTDRDGVILHSIGDADFVEKANRVALCPGVSWAEDARGTNAI
HHHHHHHHHHCCCCEEEEEECCCCEEEEECCCHHHHHHCCCEEECCCCCCHHHCCCCCHH
GTALIAGQALAVHGTEHFLRANHVLTCSCAPIVDPFGRLLGALDVSGDPRGFSPHTLALV
HHHHHHCCEEEEECHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
KMSAQLIENHLFANQCADALRVRFHAHDEFVDSLFAGLVAFSPSGALIAANRSAQFQLGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEECC
NLDALQQRGCDELFGLSFAKLAQHAAREPLACFTLTLGTGVRVRARCEFAHAQRTAVAVS
CHHHHHHCCCHHHHCCHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEHHHHHHHHEEEEE
ARAAPTRATDAARDEEPDAITFATLDTGDARMTAVLQRVGKVRGRDLPVLVLGETGTGKE
CCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCHH
WLARALHHASPRRDGPFVAVNCAALPDSLIEAELFGYEDGAFTGARKRGSPGKIAQADGG
HHHHHHHHCCCCCCCCEEEEEHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCC
TLFLDEIGDMPLAQQVRLMRVLQERAVMPLGGARAVPVDVRIVCATHRDLRAMIAAGTFR
EEEHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCEECCEEEEEEEECCHHHHHHHHHCCHH
EDLFYRINGLAVTLPPLAERSDLETLVARVLARLARSEPMPATVSAAVLAAFARCRWPGN
HHHHEEECCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
LRQMTNVLRTAGMLAEGEARIDVAHLPDDFWLDCDARARDATPPRTCADAAAGAAAAGAS
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCEECCCCCCCCCCCCHHHHHHHCCHHHCCCC
TLQDHQVALIDGALDRHRGNVSAAARELGLARNTVYRHLRRRRSRE
HHCCCEEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1378052 [H]