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The map label for this gene is feaR [H]

Identifier: 126443771

GI number: 126443771

Start: 2085732

End: 2086787

Strand: Reverse

Name: feaR [H]

Synonym: BURPS668_A2148

Alternate gene names: 126443771

Gene position: 2086787-2085732 (Counterclockwise)

Preceding gene: 126444911

Following gene: 126443511

Centisome position: 66.72

GC content: 71.5

Gene sequence:

>1056_bases
ATGGCGAAGATGCACGCGCCCCGCGGCGGCACGCTGCTGCAATTCTTTTCGACCGACGACATGCCGCTCGCGCGCGCGGC
GGCGTTCTGGAGCGCGCACGTGTTCCAGTGCGAGGACGTGCGCGCGTCGTCCGCGCGCGCGTTTCACGGGCACGGCTTTC
TGTGCCGCTGCGAGCGCGGCCGGTTCGTTCGCTTTCGCGGCGCGTCGCTCGACACGCGCATCGGCGCGGCGTGGCTGAGC
GCCGCGCCAGCCGATGCGTACGTGACGATCTGCGCGCTGCATGCGGGCGAGTGCACGGTCGAAGCGCCCGGCTTGCCGGA
TGTGCGCTTTCGTGCGAACGAGCTGTTCATGCTGGACGGCGGGCAGCCGATGCGCGTGCGCTGGAGCGAGCCGTGTTTCA
GCGCGCTCAGGCTGCCGCGCGCATCGGTGGGGCGCACGCTCGGCCAGGCGGCGATGGACGCGTCGCCGGGCGCGGCTTCG
TTGCAGGAGGCGCGGCTCGCGCCGTTTCTCGCGGCGGAGCTCGCGCTGATCGGCGGTCGCGGCCCGACGCTGTCGTCGGA
CGAGCTCGATTACATGCTCGCGCGCGCAGCCGAGCTCGGCCGCACGCTGCTTCAGGCGGCGCTGTCGTCGCGCGCGCGGC
GCGGCGCGCCCGCGCGCGCCGACCGGCTGCAGGCCGCGTATCGCTACATCGAGCAGCATCTTCATCTGCCGACGCTCACA
CCCGAGCGGATCGCCGACGCGATCCATTGCTCGCGCACGCAGCTCTATCGGCTGTTCCGCCATGAATCGCAGACGGTGAA
GGCGGCGCTGCGCGACGCGCGGCTGAACCGCAGCCTCGGCTATCTCGAGCAGCCCGAGGTTACGCTCAGCATCGGCGAGA
TCGCGCATGCTTGCGGTTTTCCCGATCAGTCGACGTTCGGCAAGCTGTTTCGCCGGCGCTTCGGCAGAACGCCCGGCGAG
GTGCGCCGCGCCGCGCGGGGGCGTTGCAATGAAACCGTGTTGCCCGACTGCGCGGAAAGCGGCGACGCGGCGGATGTGCA
AACGCCGCGGCGGTGA

Upstream 100 bases:

>100_bases
CTGCGACTGCGACTGCGACTGCGACTGCGACATGCGACATGCGTTCCGCACGGATTCTCGTCCAACGCGCTTCCCGTCGC
ACCATTCACCGGCTCTCACC

Downstream 100 bases:

>100_bases
AAACGAGTTCCGGCGTTTCGCCGTCGCTTCGCGACGTTTCAGCGTGACGTTCGACGAAGTGCGCCGCGCCGCGCGGGGAT
GCCGATATGACGTTGCGCCG

Product: AraC-type DNA-binding domain-containing proteins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MAKMHAPRGGTLLQFFSTDDMPLARAAAFWSAHVFQCEDVRASSARAFHGHGFLCRCERGRFVRFRGASLDTRIGAAWLS
AAPADAYVTICALHAGECTVEAPGLPDVRFRANELFMLDGGQPMRVRWSEPCFSALRLPRASVGRTLGQAAMDASPGAAS
LQEARLAPFLAAELALIGGRGPTLSSDELDYMLARAAELGRTLLQAALSSRARRGAPARADRLQAAYRYIEQHLHLPTLT
PERIADAIHCSRTQLYRLFRHESQTVKAALRDARLNRSLGYLEQPEVTLSIGEIAHACGFPDQSTFGKLFRRRFGRTPGE
VRRAARGRCNETVLPDCAESGDAADVQTPRR

Sequences:

>Translated_351_residues
MAKMHAPRGGTLLQFFSTDDMPLARAAAFWSAHVFQCEDVRASSARAFHGHGFLCRCERGRFVRFRGASLDTRIGAAWLS
AAPADAYVTICALHAGECTVEAPGLPDVRFRANELFMLDGGQPMRVRWSEPCFSALRLPRASVGRTLGQAAMDASPGAAS
LQEARLAPFLAAELALIGGRGPTLSSDELDYMLARAAELGRTLLQAALSSRARRGAPARADRLQAAYRYIEQHLHLPTLT
PERIADAIHCSRTQLYRLFRHESQTVKAALRDARLNRSLGYLEQPEVTLSIGEIAHACGFPDQSTFGKLFRRRFGRTPGE
VRRAARGRCNETVLPDCAESGDAADVQTPRR
>Mature_350_residues
AKMHAPRGGTLLQFFSTDDMPLARAAAFWSAHVFQCEDVRASSARAFHGHGFLCRCERGRFVRFRGASLDTRIGAAWLSA
APADAYVTICALHAGECTVEAPGLPDVRFRANELFMLDGGQPMRVRWSEPCFSALRLPRASVGRTLGQAAMDASPGAASL
QEARLAPFLAAELALIGGRGPTLSSDELDYMLARAAELGRTLLQAALSSRARRGAPARADRLQAAYRYIEQHLHLPTLTP
ERIADAIHCSRTQLYRLFRHESQTVKAALRDARLNRSLGYLEQPEVTLSIGEIAHACGFPDQSTFGKLFRRRFGRTPGEV
RRAARGRCNETVLPDCAESGDAADVQTPRR

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=244, Percent_Identity=27.4590163934426, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 38461; Mature: 38330

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKMHAPRGGTLLQFFSTDDMPLARAAAFWSAHVFQCEDVRASSARAFHGHGFLCRCERG
CCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHEEECCCCCCCCCEEECCCEEEEECCC
RFVRFRGASLDTRIGAAWLSAAPADAYVTICALHAGECTVEAPGLPDVRFRANELFMLDG
CEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEEECCCEEEECCCCCCCEEECCEEEEEEC
GQPMRVRWSEPCFSALRLPRASVGRTLGQAAMDASPGAASLQEARLAPFLAAELALIGGR
CCCEEEEECCHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
GPTLSSDELDYMLARAAELGRTLLQAALSSRARRGAPARADRLQAAYRYIEQHLHLPTLT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC
PERIADAIHCSRTQLYRLFRHESQTVKAALRDARLNRSLGYLEQPEVTLSIGEIAHACGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHCCC
PDQSTFGKLFRRRFGRTPGEVRRAARGRCNETVLPDCAESGDAADVQTPRR
CCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKMHAPRGGTLLQFFSTDDMPLARAAAFWSAHVFQCEDVRASSARAFHGHGFLCRCERG
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHEEECCCCCCCCCEEECCCEEEEECCC
RFVRFRGASLDTRIGAAWLSAAPADAYVTICALHAGECTVEAPGLPDVRFRANELFMLDG
CEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEEECCCEEEECCCCCCCEEECCEEEEEEC
GQPMRVRWSEPCFSALRLPRASVGRTLGQAAMDASPGAASLQEARLAPFLAAELALIGGR
CCCEEEEECCHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
GPTLSSDELDYMLARAAELGRTLLQAALSSRARRGAPARADRLQAAYRYIEQHLHLPTLT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC
PERIADAIHCSRTQLYRLFRHESQTVKAALRDARLNRSLGYLEQPEVTLSIGEIAHACGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHCCC
PDQSTFGKLFRRRFGRTPGEVRRAARGRCNETVLPDCAESGDAADVQTPRR
CCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]