Click here to switch to the map view.

The map label for this gene is ilvC [H]

Identifier: 126443516

GI number: 126443516

Start: 482914

End: 484005

Strand: Reverse

Name: ilvC [H]

Synonym: BURPS668_A0529

Alternate gene names: 126443516

Gene position: 484005-482914 (Counterclockwise)

Preceding gene: 126444438

Following gene: 126442591

Centisome position: 15.48

GC content: 70.42

Gene sequence:

>1092_bases
GTGCGCTTCTCCCCTTCACTCCCACACGTGATACTCATGAACGATCTCATCTATCAAGACGAACATGCGTCGCTTCAACC
GCTGGAAGGGCTCACCGTCACCGTGATCGGCTACGGCATCCAGGGGCGCGCGTTCGCCGCGAATCTGCGCGACAGCGGCG
TTGCGGTGCGCGTCGGCAACATCGACGACCGCTACTTCGAGCTCGCGCGCGCGGAAGGCCACCGCGTGACGGACATCGCC
GAGGCCGTCGCGCACGCGGACATCGTGCTGCTGCTGATTCCGGACGAGGCGCACGGCGCGGTGTTCGACGTCGACATCGC
GCCGAACCTGCGCGAGGGCGCGCTGCTATGCGTCGCGCACGGGCACTCGCTCGTGCAGGGCGACGTGCGCCCGCTCGCGG
GGCGCGACCTCGCGATGCTCGCGCCGCGCATGTACGGCGATCCGATCCGCCGCTACTACCTCGCCGGCCAGGGCGCGCCC
GCGTACTTCGATATCGTCGCGGACCACACCGGCCGCGCGCGCGACAGGGTGCTCGCGATCGCGCGCGCGGTCGGCTTCAC
GCGCGCGGGCGTGATGGCGCTCGGCTACCGGCAGGAGACATTCCTCGATCTGTTCCAGGAGCAGTTCCTCGCGCCCGCGC
TCGTCGATCTCGTCGAAACGGGCTTTCAGGTGCTCGTCGAGCGCGGCTTCAACCCGAAGGCCGCGCTGCTCGAAGTCTAC
GGCTCGGGCGAGATGGGCAAGATGATGCTCGACGGCGCGGACATCGGGCTCGACGAAGTCGTCGCGCTGCAAGGCTCGCC
GACTTGCCAGGTCGGCTATCACCGCTGGCGCGGCCGCACGCTGCCCGCCGCCGTGCGCGAGCTGGCCGCGCGCGTGCTCG
ATCAGATCGACAGCGGCGACTTCTCCGCGTATCTGAAGGAACACGCGGCGAACGACTACGCAGCGCTCGATGAAGCGCGC
CGCGCGGCGCTGAAGCGGCCGCTCAACGTCGCGCACGCGCAAGTGCGCGCGGCGTTCCGGTTCCCGACCGAGGCCGCGGG
CGGGCTCTACCAGGCGGCGCCGGCCGGCGCCGAGCCGGAGCTCGCGCGATGA

Upstream 100 bases:

>100_bases
TGCCCGTGTTCGACGACGCGCTGCTGCAGCGGTATCTGCGCGGCATGTTCAACGACGACGCGGACCTGCGCGCGCTTGCC
GCCCGGCTCGACGGCGGCGA

Downstream 100 bases:

>100_bases
GCGCCCGTCGCCTCTACGTCGGCGCGACGTTCACCGCTTCGCCGCTCGATCCGCTGCTGCGCGCACGAGGCTTCGGCGAC
GTCGCGTTCGCGCGCTACAA

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacil reductoisomerase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MRFSPSLPHVILMNDLIYQDEHASLQPLEGLTVTVIGYGIQGRAFAANLRDSGVAVRVGNIDDRYFELARAEGHRVTDIA
EAVAHADIVLLLIPDEAHGAVFDVDIAPNLREGALLCVAHGHSLVQGDVRPLAGRDLAMLAPRMYGDPIRRYYLAGQGAP
AYFDIVADHTGRARDRVLAIARAVGFTRAGVMALGYRQETFLDLFQEQFLAPALVDLVETGFQVLVERGFNPKAALLEVY
GSGEMGKMMLDGADIGLDEVVALQGSPTCQVGYHRWRGRTLPAAVRELAARVLDQIDSGDFSAYLKEHAANDYAALDEAR
RAALKRPLNVAHAQVRAAFRFPTEAAGGLYQAAPAGAEPELAR

Sequences:

>Translated_363_residues
MRFSPSLPHVILMNDLIYQDEHASLQPLEGLTVTVIGYGIQGRAFAANLRDSGVAVRVGNIDDRYFELARAEGHRVTDIA
EAVAHADIVLLLIPDEAHGAVFDVDIAPNLREGALLCVAHGHSLVQGDVRPLAGRDLAMLAPRMYGDPIRRYYLAGQGAP
AYFDIVADHTGRARDRVLAIARAVGFTRAGVMALGYRQETFLDLFQEQFLAPALVDLVETGFQVLVERGFNPKAALLEVY
GSGEMGKMMLDGADIGLDEVVALQGSPTCQVGYHRWRGRTLPAAVRELAARVLDQIDSGDFSAYLKEHAANDYAALDEAR
RAALKRPLNVAHAQVRAAFRFPTEAAGGLYQAAPAGAEPELAR
>Mature_363_residues
MRFSPSLPHVILMNDLIYQDEHASLQPLEGLTVTVIGYGIQGRAFAANLRDSGVAVRVGNIDDRYFELARAEGHRVTDIA
EAVAHADIVLLLIPDEAHGAVFDVDIAPNLREGALLCVAHGHSLVQGDVRPLAGRDLAMLAPRMYGDPIRRYYLAGQGAP
AYFDIVADHTGRARDRVLAIARAVGFTRAGVMALGYRQETFLDLFQEQFLAPALVDLVETGFQVLVERGFNPKAALLEVY
GSGEMGKMMLDGADIGLDEVVALQGSPTCQVGYHRWRGRTLPAAVRELAARVLDQIDSGDFSAYLKEHAANDYAALDEAR
RAALKRPLNVAHAQVRAAFRFPTEAAGGLYQAAPAGAEPELAR

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family [H]

Homologues:

Organism=Escherichia coli, GI1790210, Length=321, Percent_Identity=27.7258566978193, Blast_Score=82, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323387, Length=201, Percent_Identity=27.8606965174129, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116 [H]

Pfam domain/function: PF01450 IlvC; PF07991 IlvN [H]

EC number: =1.1.1.86 [H]

Molecular weight: Translated: 39321; Mature: 39321

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFSPSLPHVILMNDLIYQDEHASLQPLEGLTVTVIGYGIQGRAFAANLRDSGVAVRVGN
CCCCCCCCEEEEEHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCCEEEEECC
IDDRYFELARAEGHRVTDIAEAVAHADIVLLLIPDEAHGAVFDVDIAPNLREGALLCVAH
CCHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCCCEEEEEC
GHSLVQGDVRPLAGRDLAMLAPRMYGDPIRRYYLAGQGAPAYFDIVADHTGRARDRVLAI
CCCEECCCCCCCCCCCHHHHCCHHCCCHHHHEEEECCCCCEEEEEEECCCCCHHHHHHHH
ARAVGFTRAGVMALGYRQETFLDLFQEQFLAPALVDLVETGFQVLVERGFNPKAALLEVY
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
GSGEMGKMMLDGADIGLDEVVALQGSPTCQVGYHRWRGRTLPAAVRELAARVLDQIDSGD
CCCCCCEEEECCCCCCHHHEEEECCCCCEEECHHHHCCCCHHHHHHHHHHHHHHHCCCCC
FSAYLKEHAANDYAALDEARRAALKRPLNVAHAQVRAAFRFPTEAAGGLYQAAPAGAEPE
HHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHCCCCEECCCCCCCCC
LAR
CCC
>Mature Secondary Structure
MRFSPSLPHVILMNDLIYQDEHASLQPLEGLTVTVIGYGIQGRAFAANLRDSGVAVRVGN
CCCCCCCCEEEEEHHHHCCCCCCCCCCCCCCEEEEEEECCCCCEEEECCCCCCEEEEECC
IDDRYFELARAEGHRVTDIAEAVAHADIVLLLIPDEAHGAVFDVDIAPNLREGALLCVAH
CCHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCCCEEEEEC
GHSLVQGDVRPLAGRDLAMLAPRMYGDPIRRYYLAGQGAPAYFDIVADHTGRARDRVLAI
CCCEECCCCCCCCCCCHHHHCCHHCCCHHHHEEEECCCCCEEEEEEECCCCCHHHHHHHH
ARAVGFTRAGVMALGYRQETFLDLFQEQFLAPALVDLVETGFQVLVERGFNPKAALLEVY
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEE
GSGEMGKMMLDGADIGLDEVVALQGSPTCQVGYHRWRGRTLPAAVRELAARVLDQIDSGD
CCCCCCEEEECCCCCCHHHEEEECCCCCEEECHHHHCCCCHHHHHHHHHHHHHHHCCCCC
FSAYLKEHAANDYAALDEARRAALKRPLNVAHAQVRAAFRFPTEAAGGLYQAAPAGAEPE
HHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHCCCCEECCCCCCCCC
LAR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA