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The map label for this gene is ddpA [H]

Identifier: 126443253

GI number: 126443253

Start: 1302720

End: 1304321

Strand: Reverse

Name: ddpA [H]

Synonym: BURPS668_A1392

Alternate gene names: 126443253

Gene position: 1304321-1302720 (Counterclockwise)

Preceding gene: 126443974

Following gene: 126443764

Centisome position: 41.71

GC content: 66.1

Gene sequence:

>1602_bases
ATGACACTCTCGATGCCCAAGCTCGTCGCGGCGCTCGCCGCCGCTTCCGCGTTCGCGGCCGTCCCGGCCCGCGAAGCGCA
CGCGGCGCCGCCGAAAGACCTGTTCGTGATGGCCACGCTGCTCGACGAGTTCATCTCGCTCGATCCGGGTGAAATCTACG
AGCTCGTGCCGGAGGAATACGTCGCGAATACATACGACCGGCTGGTGCGCGTCGATCTCGCCGATCCGTCGAAATTCAAC
GGCGACGTCGCGCAATCGTGGAGCGTGAGCCCCGACGGCCTCACGTTCACGTTCAAGCTGCGCGCGGGCCTCGCGTTCCA
TTCGGGCAATCCGCTCACGGCCGACGACGTCGCGTGGTCGCTCCAGCGCGCGGCGCTGCTCGACAAGGGGCCGGCCGCGG
TGCTCGCGGGCATCGGCCTCACGAAGGCAAACGCGCTCGCGAACGTGAAGCAGCTCGACGCGCTGACGGTATCCGTCACG
ACCGACCGCAAGTACGCGCCGAGCTTCGTGCTGAACGTGCTCGGCTCGTGGCCCGCGTCGATCGTCGACAAGAAGCTGCT
GCTGTCGCACCAGCAGGGCGACGATTTCGGCAATGGCTGGCTGAAGACGCACGAGGCCGGCTCGGGCGCCTACCAGCTCG
TCAAGTGGACGGCGGGCGACAGCATCGTGCTGCAGCGCTACGACCGCTACCGGCTGCCGCTCGCGATGAAGCGGATCGTG
CTGCGCCACGTGCCCGAGGCGGCGAGCCAGCGGCTGCTGCTCGAAAGCGGCGATGTCGACGCGGCGCGCGACCTGAGCCC
CGACGATCTCGCGGCCGTCGCGAACAGCGGCAAGGCGAAGGTGACGCCGTCGCCGCAGGCGACGCTGCTGTACCTCGGCC
TCAACACGAAGAACCCGACGCTCGCGAAACCGGAGGTTCAGCAGGCGCTGAAATGGCTCGTCGATTACGACGGCATCCAG
CGCCACGTCGTGAAAACGACCTACCAGGTCCATCAGACGTTCATGCCGGAGGGCTTGCTCGGCGCGCTGAACGCGAATCC
GTACCGGCTCGACGTCGCGAAGGCGAAGGCGCTGCTCGCGAAGGCCGGCGTGCCGAACGGCTTCACGGTGACGATGGACG
TGCGCAACGACTACCCGTACACCGAGATCGCGCAGGCGGTGCAGGCGAACTTCGCGCAGGCGGGCGTCAAGGTGCAGCTG
ATTCCCGGCGACAACAAGCAGACGCTCGCGAAGTACCGTGCGCGCCAGCACGACATCTACATCGGCGAATGGTCGGCCGA
TTACATCGATCCGCACAGCAATGCGCAGGGCTTCGCATGGAACCCGGATAATTCGGATCAGTCCAGCTACAAGATGCTCG
CGTGGCGCAACGCCTGGAACATCCCGCGACTGACCGCGCAAACGGACGCGGCGCTCGCGGAGCCTTCCGCCGCGAAGCGC
GCGCAGTCATATCAGGCGATGCAAAAGGAAGTGCTCGCGAAATCGCCGTTCGTGATCCTGTTCGAGAAAGTCGCGCAGGT
CGCGACGCGGCCCGGCGTGAGCGGCCTCGAAGTCGGCCCGATCAACGATCTCGTTTCATATCGCAATCTGAAGAAGCAGT
GA

Upstream 100 bases:

>100_bases
TCGCCCGCGCCGCATGCCCGGCACGCGGCGCGCCCGGCCCTCGGCCGGGCGCGAGCGGAAACGACTGCCCCACTTCGACC
CCCAGCCCCATGGAGCGCGT

Downstream 100 bases:

>100_bases
AGCCGCTCCGGAACCCCGACATGTCGCTCCCCGCCCCTCCTCTCGAAACGCCGCGCACGCTGCCCGCGCGCCGGCCCGGC
GTGCGCTGGGCGCTGCGCGC

Product: ABC transporter periplasmic substrate-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MTLSMPKLVAALAAASAFAAVPAREAHAAPPKDLFVMATLLDEFISLDPGEIYELVPEEYVANTYDRLVRVDLADPSKFN
GDVAQSWSVSPDGLTFTFKLRAGLAFHSGNPLTADDVAWSLQRAALLDKGPAAVLAGIGLTKANALANVKQLDALTVSVT
TDRKYAPSFVLNVLGSWPASIVDKKLLLSHQQGDDFGNGWLKTHEAGSGAYQLVKWTAGDSIVLQRYDRYRLPLAMKRIV
LRHVPEAASQRLLLESGDVDAARDLSPDDLAAVANSGKAKVTPSPQATLLYLGLNTKNPTLAKPEVQQALKWLVDYDGIQ
RHVVKTTYQVHQTFMPEGLLGALNANPYRLDVAKAKALLAKAGVPNGFTVTMDVRNDYPYTEIAQAVQANFAQAGVKVQL
IPGDNKQTLAKYRARQHDIYIGEWSADYIDPHSNAQGFAWNPDNSDQSSYKMLAWRNAWNIPRLTAQTDAALAEPSAAKR
AQSYQAMQKEVLAKSPFVILFEKVAQVATRPGVSGLEVGPINDLVSYRNLKKQ

Sequences:

>Translated_533_residues
MTLSMPKLVAALAAASAFAAVPAREAHAAPPKDLFVMATLLDEFISLDPGEIYELVPEEYVANTYDRLVRVDLADPSKFN
GDVAQSWSVSPDGLTFTFKLRAGLAFHSGNPLTADDVAWSLQRAALLDKGPAAVLAGIGLTKANALANVKQLDALTVSVT
TDRKYAPSFVLNVLGSWPASIVDKKLLLSHQQGDDFGNGWLKTHEAGSGAYQLVKWTAGDSIVLQRYDRYRLPLAMKRIV
LRHVPEAASQRLLLESGDVDAARDLSPDDLAAVANSGKAKVTPSPQATLLYLGLNTKNPTLAKPEVQQALKWLVDYDGIQ
RHVVKTTYQVHQTFMPEGLLGALNANPYRLDVAKAKALLAKAGVPNGFTVTMDVRNDYPYTEIAQAVQANFAQAGVKVQL
IPGDNKQTLAKYRARQHDIYIGEWSADYIDPHSNAQGFAWNPDNSDQSSYKMLAWRNAWNIPRLTAQTDAALAEPSAAKR
AQSYQAMQKEVLAKSPFVILFEKVAQVATRPGVSGLEVGPINDLVSYRNLKKQ
>Mature_532_residues
TLSMPKLVAALAAASAFAAVPAREAHAAPPKDLFVMATLLDEFISLDPGEIYELVPEEYVANTYDRLVRVDLADPSKFNG
DVAQSWSVSPDGLTFTFKLRAGLAFHSGNPLTADDVAWSLQRAALLDKGPAAVLAGIGLTKANALANVKQLDALTVSVTT
DRKYAPSFVLNVLGSWPASIVDKKLLLSHQQGDDFGNGWLKTHEAGSGAYQLVKWTAGDSIVLQRYDRYRLPLAMKRIVL
RHVPEAASQRLLLESGDVDAARDLSPDDLAAVANSGKAKVTPSPQATLLYLGLNTKNPTLAKPEVQQALKWLVDYDGIQR
HVVKTTYQVHQTFMPEGLLGALNANPYRLDVAKAKALLAKAGVPNGFTVTMDVRNDYPYTEIAQAVQANFAQAGVKVQLI
PGDNKQTLAKYRARQHDIYIGEWSADYIDPHSNAQGFAWNPDNSDQSSYKMLAWRNAWNIPRLTAQTDAALAEPSAAKRA
QSYQAMQKEVLAKSPFVILFEKVAQVATRPGVSGLEVGPINDLVSYRNLKKQ

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=534, Percent_Identity=28.8389513108614, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1787052, Length=431, Percent_Identity=24.8259860788863, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789966, Length=484, Percent_Identity=24.3801652892562, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787551, Length=543, Percent_Identity=24.6777163904236, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789887, Length=560, Percent_Identity=24.8214285714286, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789397, Length=558, Percent_Identity=25.089605734767, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081878, Length=523, Percent_Identity=22.9445506692161, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787495, Length=499, Percent_Identity=25.0501002004008, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 58032; Mature: 57900

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSMPKLVAALAAASAFAAVPAREAHAAPPKDLFVMATLLDEFISLDPGEIYELVPEEY
CCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCHHH
VANTYDRLVRVDLADPSKFNGDVAQSWSVSPDGLTFTFKLRAGLAFHSGNPLTADDVAWS
HHHHHHHEEEEECCCCCCCCCCHHCCCCCCCCCEEEEEEEECCEEEECCCCCCHHHHHHH
LQRAALLDKGPAAVLAGIGLTKANALANVKQLDALTVSVTTDRKYAPSFVLNVLGSWPAS
HHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHCCCCHH
IVDKKLLLSHQQGDDFGNGWLKTHEAGSGAYQLVKWTAGDSIVLQRYDRYRLPLAMKRIV
HHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEEEECCCHHEEHHHHHHCCCHHHHHHH
LRHVPEAASQRLLLESGDVDAARDLSPDDLAAVANSGKAKVTPSPQATLLYLGLNTKNPT
HHHCCHHHHCEEEEECCCCCCCCCCCHHHHHHHHCCCCEEECCCCCEEEEEEEECCCCCC
LAKPEVQQALKWLVDYDGIQRHVVKTTYQVHQTFMPEGLLGALNANPYRLDVAKAKALLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEHHHHHHHHH
KAGVPNGFTVTMDVRNDYPYTEIAQAVQANFAQAGVKVQLIPGDNKQTLAKYRARQHDIY
HCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCEE
IGEWSADYIDPHSNAQGFAWNPDNSDQSSYKMLAWRNAWNIPRLTAQTDAALAEPSAAKR
EECCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHCCCHHHHH
AQSYQAMQKEVLAKSPFVILFEKVAQVATRPGVSGLEVGPINDLVSYRNLKKQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TLSMPKLVAALAAASAFAAVPAREAHAAPPKDLFVMATLLDEFISLDPGEIYELVPEEY
CCCHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCHHH
VANTYDRLVRVDLADPSKFNGDVAQSWSVSPDGLTFTFKLRAGLAFHSGNPLTADDVAWS
HHHHHHHEEEEECCCCCCCCCCHHCCCCCCCCCEEEEEEEECCEEEECCCCCCHHHHHHH
LQRAALLDKGPAAVLAGIGLTKANALANVKQLDALTVSVTTDRKYAPSFVLNVLGSWPAS
HHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHCCCCHH
IVDKKLLLSHQQGDDFGNGWLKTHEAGSGAYQLVKWTAGDSIVLQRYDRYRLPLAMKRIV
HHHHHHHHHCCCCCCCCCCCEEECCCCCCCEEEEEEECCCHHEEHHHHHHCCCHHHHHHH
LRHVPEAASQRLLLESGDVDAARDLSPDDLAAVANSGKAKVTPSPQATLLYLGLNTKNPT
HHHCCHHHHCEEEEECCCCCCCCCCCHHHHHHHHCCCCEEECCCCCEEEEEEEECCCCCC
LAKPEVQQALKWLVDYDGIQRHVVKTTYQVHQTFMPEGLLGALNANPYRLDVAKAKALLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEHHHHHHHHH
KAGVPNGFTVTMDVRNDYPYTEIAQAVQANFAQAGVKVQLIPGDNKQTLAKYRARQHDIY
HCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCEE
IGEWSADYIDPHSNAQGFAWNPDNSDQSSYKMLAWRNAWNIPRLTAQTDAALAEPSAAKR
EECCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHCCCHHHHH
AQSYQAMQKEVLAKSPFVILFEKVAQVATRPGVSGLEVGPINDLVSYRNLKKQ
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]