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The map label for this gene is crp [C]

Identifier: 126442923

GI number: 126442923

Start: 1033132

End: 1033977

Strand: Reverse

Name: crp [C]

Synonym: BURPS668_A1075

Alternate gene names: 126442923

Gene position: 1033977-1033132 (Counterclockwise)

Preceding gene: 126443794

Following gene: 126442437

Centisome position: 33.06

GC content: 70.21

Gene sequence:

>846_bases
GTGATGACCGACGACGTCCAAGCCCCGCACCGCCCGCCGCTCGCCGCGGATGAAGCGGCCCGCGCCGACGAGGCTGCCGC
AGAGCCTGCCTCGGCGCCGGCCGAAGCGCCCGTCGAAACATCAGCCGCCGCGCCCGTGCGAGCGCCGGCCGCGGCGGCCG
GCGCGGGCGAGCTGCGCGCGCTCTTCTCCCGCTGCGGCTGGTTCAACACGCTCGCGCCCGAGCATCAGGCGCTCGTCGTC
GCGCAGTCGCACGCCGAGTACCGCGACGCGGGCGACTGGGTCGCGCGCCGGCAGGCGCCTTCCGAATACTGGATCGGCGT
GCACCGCGGGCTCGTGAAGCTCGCGATCTACAACGCGTCCGGGCGCGGCTGCACGTTCTCCGGCGTGCCGTCGGGCGGCT
GGTTCGGCGAAGGCAGCGTGATCAAGCGCGAGCTGCGCAAGTACGATGTGATCGCGATCCAGCGCTCGCTCGTGCTGTTC
GTGCCGAGCGCGACGTTCCACGCGCTCCTCGACAGCAGCCTGCCGTTCACGGGCTTCGTGATTCGACAGTTGAACAACCG
GATGGGCGAATTCATCGCGTCGATCCAGAACAGCCGGCTGCTCGACGTGAACGCGCGCGTCGCGCAGTCGCTCGCCCAGC
TGTTCAACCCGGACCTGTATCCGGACACCGGCGCGACGCTCGCGATCTCGCAGGAGGAGCTCGGGATGCTGGTCGGCGTG
TCGCGGCAGCGAATCAATCAGGCGCTTCAGCATCTCGAGCGGCTCGGCGCGGTGCGGCTCGCGTACAACCAGATCGACGT
GCTCGATCTGCCGAAGCTCGCGGCGTTCGGGATGGAGCAGATCTGA

Upstream 100 bases:

>100_bases
ATTGGACAAGCCTACTCGCGGCCATTGTGAGCCGTCTGTCATGCAAGCGACAGACTCGCCGGCCACGACCGCGCGTATTC
CCTATCCTCGCAAACCCTGT

Downstream 100 bases:

>100_bases
CGGCCCGGTTGGCGGCCGCGGCCGCCATCGCGTTCGCCGTCCATGATGCCGACCGGTCGCGGCCACGCGCGGCCTGCGCT
GTCGCCGCCGCCGTCCGCTC

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Transcription Regulator Protein; CRP/FNR Family Transcriptional Regulator; Cyclic-Nucleotide-Gated Cation Channel; CNMP Regulatory Protein; Transcriptional Regulator Crp Family; HTH Crp Family Transcriptional Regulator; Regulatory Protein; Transcriptional Regulator Crp

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MMTDDVQAPHRPPLAADEAARADEAAAEPASAPAEAPVETSAAAPVRAPAAAAGAGELRALFSRCGWFNTLAPEHQALVV
AQSHAEYRDAGDWVARRQAPSEYWIGVHRGLVKLAIYNASGRGCTFSGVPSGGWFGEGSVIKRELRKYDVIAIQRSLVLF
VPSATFHALLDSSLPFTGFVIRQLNNRMGEFIASIQNSRLLDVNARVAQSLAQLFNPDLYPDTGATLAISQEELGMLVGV
SRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI

Sequences:

>Translated_281_residues
MMTDDVQAPHRPPLAADEAARADEAAAEPASAPAEAPVETSAAAPVRAPAAAAGAGELRALFSRCGWFNTLAPEHQALVV
AQSHAEYRDAGDWVARRQAPSEYWIGVHRGLVKLAIYNASGRGCTFSGVPSGGWFGEGSVIKRELRKYDVIAIQRSLVLF
VPSATFHALLDSSLPFTGFVIRQLNNRMGEFIASIQNSRLLDVNARVAQSLAQLFNPDLYPDTGATLAISQEELGMLVGV
SRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI
>Mature_281_residues
MMTDDVQAPHRPPLAADEAARADEAAAEPASAPAEAPVETSAAAPVRAPAAAAGAGELRALFSRCGWFNTLAPEHQALVV
AQSHAEYRDAGDWVARRQAPSEYWIGVHRGLVKLAIYNASGRGCTFSGVPSGGWFGEGSVIKRELRKYDVIAIQRSLVLF
VPSATFHALLDSSLPFTGFVIRQLNNRMGEFIASIQNSRLLDVNARVAQSLAQLFNPDLYPDTGATLAISQEELGMLVGV
SRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30313; Mature: 30313

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTDDVQAPHRPPLAADEAARADEAAAEPASAPAEAPVETSAAAPVRAPAAAAGAGELRA
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHH
LFSRCGWFNTLAPEHQALVVAQSHAEYRDAGDWVARRQAPSEYWIGVHRGLVKLAIYNAS
HHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCEEEEEEECCC
GRGCTFSGVPSGGWFGEGSVIKRELRKYDVIAIQRSLVLFVPSATFHALLDSSLPFTGFV
CCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHEECEEEEEECCHHHHHHHHCCCCHHHHH
IRQLNNRMGEFIASIQNSRLLDVNARVAQSLAQLFNPDLYPDTGATLAISQEELGMLVGV
HHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHH
SRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCC
>Mature Secondary Structure
MMTDDVQAPHRPPLAADEAARADEAAAEPASAPAEAPVETSAAAPVRAPAAAAGAGELRA
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHH
LFSRCGWFNTLAPEHQALVVAQSHAEYRDAGDWVARRQAPSEYWIGVHRGLVKLAIYNAS
HHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCEEEEEEECCC
GRGCTFSGVPSGGWFGEGSVIKRELRKYDVIAIQRSLVLFVPSATFHALLDSSLPFTGFV
CCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHEECEEEEEECCHHHHHHHHCCCCHHHHH
IRQLNNRMGEFIASIQNSRLLDVNARVAQSLAQLFNPDLYPDTGATLAISQEELGMLVGV
HHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHH
SRQRINQALQHLERLGAVRLAYNQIDVLDLPKLAAFGMEQI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA