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The map label for this gene is selA [H]

Identifier: 126442780

GI number: 126442780

Start: 2314363

End: 2315805

Strand: Reverse

Name: selA [H]

Synonym: BURPS668_A2392

Alternate gene names: 126442780

Gene position: 2315805-2314363 (Counterclockwise)

Preceding gene: 126445389

Following gene: 126443505

Centisome position: 74.05

GC content: 73.94

Gene sequence:

>1443_bases
GTGAGCGGGCCCGGCGCAAGCGAACTGAACGCGCTGCTCGCGCGCGCGCCGTCGGTCGAGCGCGTGCTGTCGTCGGAGGA
AATGCAGCCGCTCGTCGACGAATACGGACGCACGCGCGCGCTCGCCGCGGTGCGCGCGTCGCTCGCCGCGTGGCGTGACG
CCGCGCGCCGCGATCCGGCCGCGGCCGGGACGCCCGACGACGCGCGCATTGCCGCCGACGTGCGCGCGCGGCTCGCCGCT
GACGCGGCGGCGGCGATGCGCGCGGTGTTCAACCTGACGGGCACCGTGCTGCATACGAACCTCGGCCGCGCACTGTTGCC
GGACGACGCGGTGCGCGCGGTCGTGCAGGCGCTCACGCAGCCGATGAATCTCGAATTCGATCTCGCGACGGGCCGCCGCG
GCGACCGCGACGATCTGATCGGCGCGCTCGCCTGCGAGCTGACGGGCGCCGAGGCGGCGACCGTCGTCAACAACAACGCG
GCCGCCGTGCTGCTCGTGCTGTCCGCGCTCGCGCCGAGGCGGGAAGTGGTCGTGTCGCGCGGCGAACTCGTCGAGATCGG
CGGCGCGTTCCGCATTCCGGACATCATGAGCCGCGCCGGCGCGAAGCTGCGCGAGGTCGGCACGACGAACCGCACGCATC
TGGCGGACTACGCGGACGCGATCGGCCCGCGCACCGCGCTGCTGATGAAAGTGCATTGCAGCAATTACGCGATCAGCGGC
TTCACGAAGGAAGTGGCGCTGCGGGAGCTCGCGCCGCTCGCGCGCGAGCGCGGGGTGCCCGTCGCCGTCGATCTCGGCAG
CGGCACGCTCGTCGACCTGACGCGCTGGGGCCTGCCGAAGGAGACGACGGTGCGCGAGACCGTCGAGGCGGGCGCGGATC
TCGTCACGTTCAGCGGCGACAAGCTGCTCGGCGGCCCGCAGGCGGGGCTCATCGTCGGGCGGCGCGATCTGATCGCGAAG
CTCAAGAAGCATCCGCTCAAGCGCGCGCTGCGCGTCGGCAAGCTGACGCTCGCCGCGCTCGAGCCGGTGCTGCGCCTGTA
CCAGACGCCGGAATTCCTGCGCGAGCGGTTGACGACGTTGCGGCTGCTCACGCGCGCGCAGGCGGACATCGCCGCGACGG
CCGAGCGCGTGCGTCCGGCGCTGCAGCGCGCGCTCGGCGCGGCGTTCGCGGTCGACGTCGAGCCGATGTTCAGCCAGATC
GGCAGCGGCGCGTTGCCCGTCGATCAATTGCCGAGCTACGGCCTCGTCGTGCGCGCGAGCGGCGGCAAGCGCCGCGGCCG
CGCGCTCGCGCAGCTCGACGCGCACCTGCGCGGCTGGCCGCGCCCGGTGCTCGGGCGCATCGCCGACGACGCGCTGCGGC
TCGACCTGCGCTGCCTCGAAGCGGGCGACGAAGCCGCGTTCATCGCGCAATGCGCGCAGGCGCCGACGGGCCCGCGCGCA
TGA

Upstream 100 bases:

>100_bases
TGCTGATGGGCGAGGCGGGCTACCGGCGCGCGTCGCCGAATCCGCTGCTGTGGCCGGACCTGCCGGCCGAGGCCGGCGCA
GCGGCGGGAGACGAGCGCAC

Downstream 100 bases:

>100_bases
TCGTCGGGACCGCAGGCCACATCGATCACGGCAAGACGACGCTCGTGCGCGCGCTGACGGGCGTCGACACCGATCGGCTG
AAGGAAGAGAAGGCGCGCGG

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MSGPGASELNALLARAPSVERVLSSEEMQPLVDEYGRTRALAAVRASLAAWRDAARRDPAAAGTPDDARIAADVRARLAA
DAAAAMRAVFNLTGTVLHTNLGRALLPDDAVRAVVQALTQPMNLEFDLATGRRGDRDDLIGALACELTGAEAATVVNNNA
AAVLLVLSALAPRREVVVSRGELVEIGGAFRIPDIMSRAGAKLREVGTTNRTHLADYADAIGPRTALLMKVHCSNYAISG
FTKEVALRELAPLARERGVPVAVDLGSGTLVDLTRWGLPKETTVRETVEAGADLVTFSGDKLLGGPQAGLIVGRRDLIAK
LKKHPLKRALRVGKLTLAALEPVLRLYQTPEFLRERLTTLRLLTRAQADIAATAERVRPALQRALGAAFAVDVEPMFSQI
GSGALPVDQLPSYGLVVRASGGKRRGRALAQLDAHLRGWPRPVLGRIADDALRLDLRCLEAGDEAAFIAQCAQAPTGPRA

Sequences:

>Translated_480_residues
MSGPGASELNALLARAPSVERVLSSEEMQPLVDEYGRTRALAAVRASLAAWRDAARRDPAAAGTPDDARIAADVRARLAA
DAAAAMRAVFNLTGTVLHTNLGRALLPDDAVRAVVQALTQPMNLEFDLATGRRGDRDDLIGALACELTGAEAATVVNNNA
AAVLLVLSALAPRREVVVSRGELVEIGGAFRIPDIMSRAGAKLREVGTTNRTHLADYADAIGPRTALLMKVHCSNYAISG
FTKEVALRELAPLARERGVPVAVDLGSGTLVDLTRWGLPKETTVRETVEAGADLVTFSGDKLLGGPQAGLIVGRRDLIAK
LKKHPLKRALRVGKLTLAALEPVLRLYQTPEFLRERLTTLRLLTRAQADIAATAERVRPALQRALGAAFAVDVEPMFSQI
GSGALPVDQLPSYGLVVRASGGKRRGRALAQLDAHLRGWPRPVLGRIADDALRLDLRCLEAGDEAAFIAQCAQAPTGPRA
>Mature_479_residues
SGPGASELNALLARAPSVERVLSSEEMQPLVDEYGRTRALAAVRASLAAWRDAARRDPAAAGTPDDARIAADVRARLAAD
AAAAMRAVFNLTGTVLHTNLGRALLPDDAVRAVVQALTQPMNLEFDLATGRRGDRDDLIGALACELTGAEAATVVNNNAA
AVLLVLSALAPRREVVVSRGELVEIGGAFRIPDIMSRAGAKLREVGTTNRTHLADYADAIGPRTALLMKVHCSNYAISGF
TKEVALRELAPLARERGVPVAVDLGSGTLVDLTRWGLPKETTVRETVEAGADLVTFSGDKLLGGPQAGLIVGRRDLIAKL
KKHPLKRALRVGKLTLAALEPVLRLYQTPEFLRERLTTLRLLTRAQADIAATAERVRPALQRALGAAFAVDVEPMFSQIG
SGALPVDQLPSYGLVVRASGGKRRGRALAQLDAHLRGWPRPVLGRIADDALRLDLRCLEAGDEAAFIAQCAQAPTGPRA

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=462, Percent_Identity=54.5454545454545, Blast_Score=426, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 50936; Mature: 50805

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPGASELNALLARAPSVERVLSSEEMQPLVDEYGRTRALAAVRASLAAWRDAARRDPA
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC
AAGTPDDARIAADVRARLAADAAAAMRAVFNLTGTVLHTNLGRALLPDDAVRAVVQALTQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHECCCCCCCCCCHHHHHHHHHHCC
PMNLEFDLATGRRGDRDDLIGALACELTGAEAATVVNNNAAAVLLVLSALAPRREVVVSR
CCCCEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHCC
GELVEIGGAFRIPDIMSRAGAKLREVGTTNRTHLADYADAIGPRTALLMKVHCSNYAISG
CCEEEECCCCCCHHHHHHCCCHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEECCCEEECC
FTKEVALRELAPLARERGVPVAVDLGSGTLVDLTRWGLPKETTVRETVEAGADLVTFSGD
HHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHCCCCCCHHHHHHHHCCCCEEEECCC
KLLGGPQAGLIVGRRDLIAKLKKHPLKRALRVGKLTLAALEPVLRLYQTPEFLRERLTTL
CCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RLLTRAQADIAATAERVRPALQRALGAAFAVDVEPMFSQIGSGALPVDQLPSYGLVVRAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCHHHHHCCCCCCCHHHCCCCCEEEECC
GGKRRGRALAQLDAHLRGWPRPVLGRIADDALRLDLRCLEAGDEAAFIAQCAQAPTGPRA
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SGPGASELNALLARAPSVERVLSSEEMQPLVDEYGRTRALAAVRASLAAWRDAARRDPA
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCC
AAGTPDDARIAADVRARLAADAAAAMRAVFNLTGTVLHTNLGRALLPDDAVRAVVQALTQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHECCCCCCCCCCHHHHHHHHHHCC
PMNLEFDLATGRRGDRDDLIGALACELTGAEAATVVNNNAAAVLLVLSALAPRREVVVSR
CCCCEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHCC
GELVEIGGAFRIPDIMSRAGAKLREVGTTNRTHLADYADAIGPRTALLMKVHCSNYAISG
CCEEEECCCCCCHHHHHHCCCHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEECCCEEECC
FTKEVALRELAPLARERGVPVAVDLGSGTLVDLTRWGLPKETTVRETVEAGADLVTFSGD
HHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEHHHCCCCCCHHHHHHHHCCCCEEEECCC
KLLGGPQAGLIVGRRDLIAKLKKHPLKRALRVGKLTLAALEPVLRLYQTPEFLRERLTTL
CCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RLLTRAQADIAATAERVRPALQRALGAAFAVDVEPMFSQIGSGALPVDQLPSYGLVVRAS
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCHHHHHCCCCCCCHHHCCCCCEEEECC
GGKRRGRALAQLDAHLRGWPRPVLGRIADDALRLDLRCLEAGDEAAFIAQCAQAPTGPRA
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA