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The map label for this gene is rpiB [H]

Identifier: 126442535

GI number: 126442535

Start: 414608

End: 415102

Strand: Reverse

Name: rpiB [H]

Synonym: BURPS668_A0454

Alternate gene names: 126442535

Gene position: 415102-414608 (Counterclockwise)

Preceding gene: 126443140

Following gene: 126445383

Centisome position: 13.27

GC content: 69.49

Gene sequence:

>495_bases
ATGAAAGTGGCGATCGGCTGCGACGAAGCGGCCTACGCGCTCAAGGAGTCGATCAAGCGGCACCTGCGCGCGACGCACCC
CGAGCTCGAGCTGGTCGACTTCGGCACGCACAGCGCGGACGAGGCGGTGCTGTATCCCGATATCGCGATCGAAGTCGCGC
AGCGCGTCGCGGCCGGCGAATTTCCGCGCGCGATCCTGCTGTGCGGCACGGGCATCGGCGTGGCGATCTCCGCGAACAAG
GTGCCGGGCATCCGCGCCGCCCAGTGCCATGACACCTACTCGGCCGAGCGCGCGCGGCGCAGCAACGACGCGCAGATCGT
CACGATGGGCGCGCGCGTGATCGGCACCGAGCTCGCGAACAGCATCGTCGACGCATGGCTTAGGGCAGAATTCGACGGCG
GCCGCTCGCAGCCGAAGGTGCAGCGGATCGCCGACTACGAACGCCGGGCGGGCCTCACCCAGGCCGGCCCGAATGACGCG
CACCGCGGTTCATGA

Upstream 100 bases:

>100_bases
TATGAGCAAAATTTCGCCCTTTGCCAAATGTTCAGACGGGTCGCTATAATTGCTCAACACTGCACATTTGCGCACTCATC
TTGCCCTCCGGAGGTTCACC

Downstream 100 bases:

>100_bases
CGCCGCGCAGCGCGCCGCTCCACTCGATCACGACATGACGAACGAAGAACTCACGCAACTCGCAAAGTGCTATTACGTCG
ACGGGTTGACGCAGGAAGAA

Product: ribose 5-phosphate isomerase B

Products: D-Ribulose 5-phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MKVAIGCDEAAYALKESIKRHLRATHPELELVDFGTHSADEAVLYPDIAIEVAQRVAAGEFPRAILLCGTGIGVAISANK
VPGIRAAQCHDTYSAERARRSNDAQIVTMGARVIGTELANSIVDAWLRAEFDGGRSQPKVQRIADYERRAGLTQAGPNDA
HRGS

Sequences:

>Translated_164_residues
MKVAIGCDEAAYALKESIKRHLRATHPELELVDFGTHSADEAVLYPDIAIEVAQRVAAGEFPRAILLCGTGIGVAISANK
VPGIRAAQCHDTYSAERARRSNDAQIVTMGARVIGTELANSIVDAWLRAEFDGGRSQPKVQRIADYERRAGLTQAGPNDA
HRGS
>Mature_164_residues
MKVAIGCDEAAYALKESIKRHLRATHPELELVDFGTHSADEAVLYPDIAIEVAQRVAAGEFPRAILLCGTGIGVAISANK
VPGIRAAQCHDTYSAERARRSNDAQIVTMGARVIGTELANSIVDAWLRAEFDGGRSQPKVQRIADYERRAGLTQAGPNDA
HRGS

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family [H]

Homologues:

Organism=Escherichia coli, GI1790528, Length=148, Percent_Identity=46.6216216216216, Blast_Score=134, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003500
- InterPro:   IPR004785 [H]

Pfam domain/function: PF02502 LacAB_rpiB [H]

EC number: 5.3.1.6 [C]

Molecular weight: Translated: 17621; Mature: 17621

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAIGCDEAAYALKESIKRHLRATHPELELVDFGTHSADEAVLYPDIAIEVAQRVAAGE
CEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECCHHHHHHHHHHHCCC
FPRAILLCGTGIGVAISANKVPGIRAAQCHDTYSAERARRSNDAQIVTMGARVIGTELAN
CCCEEEEECCCCEEEEECCCCCCCCCHHHCCHHHHHHHHCCCCCEEEEECHHHHHHHHHH
SIVDAWLRAEFDGGRSQPKVQRIADYERRAGLTQAGPNDAHRGS
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKVAIGCDEAAYALKESIKRHLRATHPELELVDFGTHSADEAVLYPDIAIEVAQRVAAGE
CEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECCHHHHHHHHHHHCCC
FPRAILLCGTGIGVAISANKVPGIRAAQCHDTYSAERARRSNDAQIVTMGARVIGTELAN
CCCEEEEECCCCEEEEECCCCCCCCCHHHCCHHHHHHHHCCCCCEEEEECHHHHHHHHHH
SIVDAWLRAEFDGGRSQPKVQRIADYERRAGLTQAGPNDAHRGS
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 4.4 {D-ribose} 0.83 {D-ribose} [C]

Substrates: alpha-D-Ribose 5-phosphate [C]

Specific reaction: alpha-D-Ribose 5-phosphate <==> D-Ribulose 5-phosphate [C]

General reaction: Intramolecular oxidoreduction; Isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]