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The map label for this gene is yaaU [H]

Identifier: 126442482

GI number: 126442482

Start: 1458934

End: 1460403

Strand: Reverse

Name: yaaU [H]

Synonym: BURPS668_A1518

Alternate gene names: 126442482

Gene position: 1460403-1458934 (Counterclockwise)

Preceding gene: 126442893

Following gene: 126445043

Centisome position: 46.7

GC content: 70.0

Gene sequence:

>1470_bases
GTGAGCACACTCGATCTCGACGCGCCGATCTCGACGCCGATCCGCACCGCGAGCGACGTTTCGCGCCTCATCAACGCATC
GGGCGCGCGCGCGAACCACGCGCGCGTGATCGTCCTGCTCGCGCTCGGCGGCGTGTTCCTCGATGCGTACGATCTGACCA
CGCTGTCGTACGGCATCGAGGACGTGACCCGCGAGTTCGGCCTGACGCCGGCGCTGAGCGGGCTCGTCAGCGCGTCGATC
ATGATCGGCACGATCCTCGGCAGCCTGCTCGGCGGCTGGTTCACCGACAAGGTCGGCCGCTACCGCGTGTTCATGGCCGA
CATGCTCTGCTTCGTCGTCGCCGCGATCGTGGCCGGACTCGCGCCGAACGTAGAGGTGCTGATCGCCGCGCGCTTCGTGA
TGGGGCTCGGCGTCGGCATCGATCTGCCGGTCGCGATGGCGTTCCTGGCCGAGTTCTCGAAATTCGGCGGGCGCGGCAAC
AAGGCGTCGCGGCTCGCCGCGTGGTGCCCGATGTGGTACGCGGCGTCGTCCGTGTGCTTCCTGATCGTGTTCGGGCTGTA
TTTCGCGCTGCCCGCCGAGCACGCGCGCTGGCTGTGGCGCGCGTCGCTGATCTTCGGCGCGGTGCCGGCGCTCGCGATCA
TCGCGGTACGCGGCCGCTACATGAACGAATCGCCGCTGTGGGCCGCGAATCAAGGCAAGCTGCGCGACGCCGCGCGCATC
CTGCGCGAGTCGTACGGGATCCGCGCGCATGCGGCCGACGACACGCCGCGCGCGGCACCGTCGCAGCCGCCCGTCAGTTT
TCGCGTGCTGTTCAGGCAGCCGTACCTGCCGCGCACGCTCGTCGCGAGCGCGATGAATCTGTGCATCCCGTTCGAATACA
CGGCGATCGCGTTCTTCCTGCCGACGATCCTGACGCAGTTCCTCGGCGCGGGCGTGTTCGAGACGATCGCCGCGACGCTC
GCGCTCAACGTGCTGTTCGCGCTCACGGGCGGGTTGCTCGGCATGCGCCTCGCGTACCGGCTGCCGTCGCGGCGCGTCGC
GATCGCCGGCTTCGCGTTGCAGGCCGCGGCGCTCGTCACGCTCGCGCTGCTCGGCCATCCGCGGACCGCGCTCGGCATCG
GCGCCGCGGTGCTGATGCTCGGCCTGTGGCTGTTCGCCGAAGGCTTCGGCCCCGGCGCGCAGATGATGATCTATCCGGCG
CTGTCGTATCCGGCGTCGATTCGCGGCACGGGGCTCGGCTTCGGGCGTGCGCTGACGGGCATCGGCAGCGCGTTCGCGCT
GTTCGTGCTGCCGATCCTCAACGCGCGCCTCGGCGCCGGCATGTTCTGGATCGTGGCGATCGCGGCATTCGTGCCGATCG
TGTTTCTCGCGGCGATTCGCTTCGAGCCGACCGCGCGCGATGTCGATGTCGACATCGATGCCGGCCCGCGTGCGCAAGGC
GATCGAGCGCGCGTGCGCGCCGCCGCGTAG

Upstream 100 bases:

>100_bases
GCGTCTCATAACGAATCGCGAACTGCTTCTTTGTGTTTTACGGGCCCGCTTCGTATAACTGCGACTTGCCGTCCGAACCG
CCCCAACCGAAGAGCTTCCC

Downstream 100 bases:

>100_bases
GCGGCGCGGCGGCCGCGTGTCGGCATGCGCGCGCCGCGTGGCCGTCGCGCCGCGGCAGCGCCCAGTGCGCCGCAGGCGGC
CGCCCGAGCCGGCGCCGACG

Product: major facilitator superfamily permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MSTLDLDAPISTPIRTASDVSRLINASGARANHARVIVLLALGGVFLDAYDLTTLSYGIEDVTREFGLTPALSGLVSASI
MIGTILGSLLGGWFTDKVGRYRVFMADMLCFVVAAIVAGLAPNVEVLIAARFVMGLGVGIDLPVAMAFLAEFSKFGGRGN
KASRLAAWCPMWYAASSVCFLIVFGLYFALPAEHARWLWRASLIFGAVPALAIIAVRGRYMNESPLWAANQGKLRDAARI
LRESYGIRAHAADDTPRAAPSQPPVSFRVLFRQPYLPRTLVASAMNLCIPFEYTAIAFFLPTILTQFLGAGVFETIAATL
ALNVLFALTGGLLGMRLAYRLPSRRVAIAGFALQAAALVTLALLGHPRTALGIGAAVLMLGLWLFAEGFGPGAQMMIYPA
LSYPASIRGTGLGFGRALTGIGSAFALFVLPILNARLGAGMFWIVAIAAFVPIVFLAAIRFEPTARDVDVDIDAGPRAQG
DRARVRAAA

Sequences:

>Translated_489_residues
MSTLDLDAPISTPIRTASDVSRLINASGARANHARVIVLLALGGVFLDAYDLTTLSYGIEDVTREFGLTPALSGLVSASI
MIGTILGSLLGGWFTDKVGRYRVFMADMLCFVVAAIVAGLAPNVEVLIAARFVMGLGVGIDLPVAMAFLAEFSKFGGRGN
KASRLAAWCPMWYAASSVCFLIVFGLYFALPAEHARWLWRASLIFGAVPALAIIAVRGRYMNESPLWAANQGKLRDAARI
LRESYGIRAHAADDTPRAAPSQPPVSFRVLFRQPYLPRTLVASAMNLCIPFEYTAIAFFLPTILTQFLGAGVFETIAATL
ALNVLFALTGGLLGMRLAYRLPSRRVAIAGFALQAAALVTLALLGHPRTALGIGAAVLMLGLWLFAEGFGPGAQMMIYPA
LSYPASIRGTGLGFGRALTGIGSAFALFVLPILNARLGAGMFWIVAIAAFVPIVFLAAIRFEPTARDVDVDIDAGPRAQG
DRARVRAAA
>Mature_488_residues
STLDLDAPISTPIRTASDVSRLINASGARANHARVIVLLALGGVFLDAYDLTTLSYGIEDVTREFGLTPALSGLVSASIM
IGTILGSLLGGWFTDKVGRYRVFMADMLCFVVAAIVAGLAPNVEVLIAARFVMGLGVGIDLPVAMAFLAEFSKFGGRGNK
ASRLAAWCPMWYAASSVCFLIVFGLYFALPAEHARWLWRASLIFGAVPALAIIAVRGRYMNESPLWAANQGKLRDAARIL
RESYGIRAHAADDTPRAAPSQPPVSFRVLFRQPYLPRTLVASAMNLCIPFEYTAIAFFLPTILTQFLGAGVFETIAATLA
LNVLFALTGGLLGMRLAYRLPSRRVAIAGFALQAAALVTLALLGHPRTALGIGAAVLMLGLWLFAEGFGPGAQMMIYPAL
SYPASIRGTGLGFGRALTGIGSAFALFVLPILNARLGAGMFWIVAIAAFVPIVFLAAIRFEPTARDVDVDIDAGPRAQGD
RARVRAAA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI7662270, Length=324, Percent_Identity=22.8395061728395, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786229, Length=451, Percent_Identity=27.7161862527716, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87082159, Length=410, Percent_Identity=31.219512195122, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788074, Length=379, Percent_Identity=29.023746701847, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788068, Length=368, Percent_Identity=27.7173913043478, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789207, Length=184, Percent_Identity=31.5217391304348, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789312, Length=479, Percent_Identity=25.678496868476, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 51959; Mature: 51828

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLDLDAPISTPIRTASDVSRLINASGARANHARVIVLLALGGVFLDAYDLTTLSYGIE
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
DVTREFGLTPALSGLVSASIMIGTILGSLLGGWFTDKVGRYRVFMADMLCFVVAAIVAGL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCC
APNVEVLIAARFVMGLGVGIDLPVAMAFLAEFSKFGGRGNKASRLAAWCPMWYAASSVCF
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LIVFGLYFALPAEHARWLWRASLIFGAVPALAIIAVRGRYMNESPLWAANQGKLRDAARI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
LRESYGIRAHAADDTPRAAPSQPPVSFRVLFRQPYLPRTLVASAMNLCIPFEYTAIAFFL
HHHHCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHH
PTILTQFLGAGVFETIAATLALNVLFALTGGLLGMRLAYRLPSRRVAIAGFALQAAALVT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
LALLGHPRTALGIGAAVLMLGLWLFAEGFGPGAQMMIYPALSYPASIRGTGLGFGRALTG
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHH
IGSAFALFVLPILNARLGAGMFWIVAIAAFVPIVFLAAIRFEPTARDVDVDIDAGPRAQG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
DRARVRAAA
CCCHHCCCC
>Mature Secondary Structure 
STLDLDAPISTPIRTASDVSRLINASGARANHARVIVLLALGGVFLDAYDLTTLSYGIE
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
DVTREFGLTPALSGLVSASIMIGTILGSLLGGWFTDKVGRYRVFMADMLCFVVAAIVAGL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCC
APNVEVLIAARFVMGLGVGIDLPVAMAFLAEFSKFGGRGNKASRLAAWCPMWYAASSVCF
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LIVFGLYFALPAEHARWLWRASLIFGAVPALAIIAVRGRYMNESPLWAANQGKLRDAARI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
LRESYGIRAHAADDTPRAAPSQPPVSFRVLFRQPYLPRTLVASAMNLCIPFEYTAIAFFL
HHHHCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHH
PTILTQFLGAGVFETIAATLALNVLFALTGGLLGMRLAYRLPSRRVAIAGFALQAAALVT
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
LALLGHPRTALGIGAAVLMLGLWLFAEGFGPGAQMMIYPALSYPASIRGTGLGFGRALTG
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHH
IGSAFALFVLPILNARLGAGMFWIVAIAAFVPIVFLAAIRFEPTARDVDVDIDAGPRAQG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
DRARVRAAA
CCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503 [H]