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The map label for this gene is fadE25 [H]

Identifier: 126442363

GI number: 126442363

Start: 1758030

End: 1759790

Strand: Reverse

Name: fadE25 [H]

Synonym: BURPS668_A1799

Alternate gene names: 126442363

Gene position: 1759790-1758030 (Counterclockwise)

Preceding gene: 126443518

Following gene: 126445289

Centisome position: 56.27

GC content: 70.02

Gene sequence:

>1761_bases
ATGAGCCTGAACCATGCGCCGTTCGCGCTCGCGAGCGCGTTCGACCGTTACCTCGGCGATCCGTCGATGCCCGACAACGC
GTTTTCATACGCGCGATGCGCGCAACTGGATGCGCACGAGCGCTTTCCCGACGCCGTCTGCGCGATGCTGTCCCAGTGGG
GGCTGCATCGCTATTACGTGCCCGAGCGGTTCGGCGGCATGCTGCGCGATTTCGAGCAGCCGCTGCAACTGATCCGGATG
CTCGCGCGCCGCGACCTGACCGTCGCGATCGGCCACGGCAAGACTTTTCTCGGCGCGGTTTGCGTGTGGGTGGGCGCGAC
GCACGAGCAGGCGTCGCGCTTCGCGCGCCGGATAGGCGACGGCGCGATCGTATCGTGGGGGCTGACCGAGCGCGAGCACG
GCAGCGATCTGCTGCGCAGCGATACGTATGCCGAAGCCGACGGCGACGAATACCGGATCGCCGGCGAGAAATGGCTGATC
AACAACGCGACGCGCGGCGACATGATCAGCCTGCTCGCCCGCACGCGGCGCGAAGGCGGCCCCCGCGGCTTCGACATGCT
GCTCGTCGACAAGCACGCACTGTCCCAAGGCCGCTTTCGCCCGCTGCCGAAGGAGCGCACGCACGGCATCCGCGGCGCCG
ATATCAGCGGCATCGCGTTCGACGATGCGAGGATACCGGCGAGCGCGCGAATCGGCGCGCGCGGCGCGGGCCTCGAAACC
GTGCTCAAGGGCTTGCAGCTCACGCGCACGCTTTGCGCGTCGCTGTCGCTCGGCGCGGGCGATCATGCGCTGCGGCTCGC
GCTGGGCTTCGCGTGCGAGCGCCGGCTGTACGGCCGCACGCTGATCGATCTGCCGAACGCGCGGCGCACGCTGATCGACG
CGTATACGGATCAACTGCTCGCCGAAGCCGCCGCGCTCGTCGGGGCGCGAAGCATCCAGGCATTGCCCGACGAGATGAGC
GTGACGTCCGCGGTCGTCAAGTATCTCGTGCCCACGCGCGCGGAGGCGATGCTCGACACGCTCGCCGAGTTGCTCGGCGC
GCGCGCGTTCTTAGCCGATACATACGCGCACGGGATGTTCCAGAAAGTGCAGCGCGACAATCGGATCGTGTCGTTGTTCG
ACGGAAACACGCTCGTCAATCTGAACGCGATCGTCAATGCGTTCCAGACGCTGGCGAAGCGCTATCGCGGGCGCGACGGC
GCCGACGCCGGACAGGCGCTCGCCGCGTTCGATCTGGGCATGCCGCTGCCGGCGTTCGATCGCGGCGCGCTCAGCCTCGT
GTCGCGGCACGGCTGCCGCGTCGTCGGCGCGTTGCCGGCGTTGGCCGACGGCATCGCGCAGCGCGCGGCATGCGAGCCGG
CGCTGTCGCGCCTGGTGGCGCCGGTTCGCAGGCTCGCCACGCTGACGGACGACGTGCACCGGCGGATGCTCGCGTGCCCG
CCGGTTCGCGTGCACGTGCCCGTCGAACAATTCGAGCTCGCGAAGCGCTATGCGCTGTGCCATGCGGCGGCGTCGGCGCT
CGGGCTGTGGTGGCATACGCGGCATCGCGTCGGCGAGGCGAGCGCCGCGCCGCCGTGGCGGGACGGCCTGTGGCTGCGCG
CGGTGCTGCGGCGGGTGCGCGTCGCGCTGGGCGACGCGGCCGATTTCGACGACGAGGCGGGCGACGCATTATGGCGCGCG
CTGCTGCGTCAGCATCGCGACGGCCTGCTGTTTTCGCTGCTGCCGTGCGAGCTTGCCGAGCATCGAGGGGAGGCCGCATG
A

Upstream 100 bases:

>100_bases
CGCGGCTGCGCGTGCTGCACGAGGATATCCAGGTGCCGGTTCGGTCGTTGCGTGTGGCCGCGGGCGAGGGCGTCGCGCAG
GATGCCTCCCGGGGCGCCGC

Downstream 100 bases:

>100_bases
GCGCCGATGCGATCTTGACCGGGCGCGAGCGCGCGCACCGCCGCGTCGACGCGGCCGGGCCGCATGCCGATCTCGAGCAA
GCGCTCGGCGATCCGTTCGA

Product: Acyl-CoA dehydrogenases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 586; Mature: 585

Protein sequence:

>586_residues
MSLNHAPFALASAFDRYLGDPSMPDNAFSYARCAQLDAHERFPDAVCAMLSQWGLHRYYVPERFGGMLRDFEQPLQLIRM
LARRDLTVAIGHGKTFLGAVCVWVGATHEQASRFARRIGDGAIVSWGLTEREHGSDLLRSDTYAEADGDEYRIAGEKWLI
NNATRGDMISLLARTRREGGPRGFDMLLVDKHALSQGRFRPLPKERTHGIRGADISGIAFDDARIPASARIGARGAGLET
VLKGLQLTRTLCASLSLGAGDHALRLALGFACERRLYGRTLIDLPNARRTLIDAYTDQLLAEAAALVGARSIQALPDEMS
VTSAVVKYLVPTRAEAMLDTLAELLGARAFLADTYAHGMFQKVQRDNRIVSLFDGNTLVNLNAIVNAFQTLAKRYRGRDG
ADAGQALAAFDLGMPLPAFDRGALSLVSRHGCRVVGALPALADGIAQRAACEPALSRLVAPVRRLATLTDDVHRRMLACP
PVRVHVPVEQFELAKRYALCHAAASALGLWWHTRHRVGEASAAPPWRDGLWLRAVLRRVRVALGDAADFDDEAGDALWRA
LLRQHRDGLLFSLLPCELAEHRGEAA

Sequences:

>Translated_586_residues
MSLNHAPFALASAFDRYLGDPSMPDNAFSYARCAQLDAHERFPDAVCAMLSQWGLHRYYVPERFGGMLRDFEQPLQLIRM
LARRDLTVAIGHGKTFLGAVCVWVGATHEQASRFARRIGDGAIVSWGLTEREHGSDLLRSDTYAEADGDEYRIAGEKWLI
NNATRGDMISLLARTRREGGPRGFDMLLVDKHALSQGRFRPLPKERTHGIRGADISGIAFDDARIPASARIGARGAGLET
VLKGLQLTRTLCASLSLGAGDHALRLALGFACERRLYGRTLIDLPNARRTLIDAYTDQLLAEAAALVGARSIQALPDEMS
VTSAVVKYLVPTRAEAMLDTLAELLGARAFLADTYAHGMFQKVQRDNRIVSLFDGNTLVNLNAIVNAFQTLAKRYRGRDG
ADAGQALAAFDLGMPLPAFDRGALSLVSRHGCRVVGALPALADGIAQRAACEPALSRLVAPVRRLATLTDDVHRRMLACP
PVRVHVPVEQFELAKRYALCHAAASALGLWWHTRHRVGEASAAPPWRDGLWLRAVLRRVRVALGDAADFDDEAGDALWRA
LLRQHRDGLLFSLLPCELAEHRGEAA
>Mature_585_residues
SLNHAPFALASAFDRYLGDPSMPDNAFSYARCAQLDAHERFPDAVCAMLSQWGLHRYYVPERFGGMLRDFEQPLQLIRML
ARRDLTVAIGHGKTFLGAVCVWVGATHEQASRFARRIGDGAIVSWGLTEREHGSDLLRSDTYAEADGDEYRIAGEKWLIN
NATRGDMISLLARTRREGGPRGFDMLLVDKHALSQGRFRPLPKERTHGIRGADISGIAFDDARIPASARIGARGAGLETV
LKGLQLTRTLCASLSLGAGDHALRLALGFACERRLYGRTLIDLPNARRTLIDAYTDQLLAEAAALVGARSIQALPDEMSV
TSAVVKYLVPTRAEAMLDTLAELLGARAFLADTYAHGMFQKVQRDNRIVSLFDGNTLVNLNAIVNAFQTLAKRYRGRDGA
DAGQALAAFDLGMPLPAFDRGALSLVSRHGCRVVGALPALADGIAQRAACEPALSRLVAPVRRLATLTDDVHRRMLACPP
VRVHVPVEQFELAKRYALCHAAASALGLWWHTRHRVGEASAAPPWRDGLWLRAVLRRVRVALGDAADFDDEAGDALWRAL
LRQHRDGLLFSLLPCELAEHRGEAA

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=354, Percent_Identity=25.9887005649718, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4557231, Length=354, Percent_Identity=23.728813559322, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI187960098, Length=354, Percent_Identity=23.728813559322, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI7656849, Length=390, Percent_Identity=26.4102564102564, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI4501859, Length=352, Percent_Identity=22.7272727272727, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI21361497, Length=363, Percent_Identity=22.8650137741047, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI76496475, Length=351, Percent_Identity=21.9373219373219, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4557235, Length=351, Percent_Identity=21.9373219373219, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4501857, Length=193, Percent_Identity=26.4248704663212, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=21.2209302325581, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI226958412, Length=344, Percent_Identity=21.2209302325581, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508101, Length=358, Percent_Identity=24.5810055865922, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=22.5721784776903, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17570075, Length=326, Percent_Identity=25.1533742331288, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17506239, Length=358, Percent_Identity=23.463687150838, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=374, Percent_Identity=23.7967914438503, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17538396, Length=332, Percent_Identity=22.5903614457831, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=346, Percent_Identity=22.5433526011561, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71982178, Length=225, Percent_Identity=24, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=228, Percent_Identity=25, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71990804, Length=264, Percent_Identity=23.4848484848485, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=264, Percent_Identity=23.1060606060606, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17533517, Length=291, Percent_Identity=24.7422680412371, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17551932, Length=411, Percent_Identity=22.8710462287105, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI281363737, Length=529, Percent_Identity=23.2514177693762, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24666513, Length=354, Percent_Identity=22.8813559322034, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24660351, Length=353, Percent_Identity=24.0793201133144, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646207, Length=357, Percent_Identity=24.6498599439776, Blast_Score=83, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21356377, Length=353, Percent_Identity=22.6628895184136, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355753, Length=258, Percent_Identity=23.2558139534884, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 64166; Mature: 64035

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNHAPFALASAFDRYLGDPSMPDNAFSYARCAQLDAHERFPDAVCAMLSQWGLHRYYV
CCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHCCHHHHHHHHHHCCCCEEEC
PERFGGMLRDFEQPLQLIRMLARRDLTVAIGHGKTFLGAVCVWVGATHEQASRFARRIGD
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHCCC
GAIVSWGLTEREHGSDLLRSDTYAEADGDEYRIAGEKWLINNATRGDMISLLARTRREGG
CCEEECCCCCCCCCHHHHHCCCCCCCCCCCEEECCCEEEECCCCCHHHHHHHHHHHHCCC
PRGFDMLLVDKHALSQGRFRPLPKERTHGIRGADISGIAFDDARIPASARIGARGAGLET
CCCCEEEEEEHHHHCCCCCCCCCHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHH
VLKGLQLTRTLCASLSLGAGDHALRLALGFACERRLYGRTLIDLPNARRTLIDAYTDQLL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHH
AEAAALVGARSIQALPDEMSVTSAVVKYLVPTRAEAMLDTLAELLGARAFLADTYAHGMF
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKVQRDNRIVSLFDGNTLVNLNAIVNAFQTLAKRYRGRDGADAGQALAAFDLGMPLPAFD
HHHHCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCC
RGALSLVSRHGCRVVGALPALADGIAQRAACEPALSRLVAPVRRLATLTDDVHRRMLACP
HHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVRVHVPVEQFELAKRYALCHAAASALGLWWHTRHRVGEASAAPPWRDGLWLRAVLRRVR
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
VALGDAADFDDEAGDALWRALLRQHRDGLLFSLLPCELAEHRGEAA
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SLNHAPFALASAFDRYLGDPSMPDNAFSYARCAQLDAHERFPDAVCAMLSQWGLHRYYV
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHCCHHHHHHHHHHCCCCEEEC
PERFGGMLRDFEQPLQLIRMLARRDLTVAIGHGKTFLGAVCVWVGATHEQASRFARRIGD
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHCCC
GAIVSWGLTEREHGSDLLRSDTYAEADGDEYRIAGEKWLINNATRGDMISLLARTRREGG
CCEEECCCCCCCCCHHHHHCCCCCCCCCCCEEECCCEEEECCCCCHHHHHHHHHHHHCCC
PRGFDMLLVDKHALSQGRFRPLPKERTHGIRGADISGIAFDDARIPASARIGARGAGLET
CCCCEEEEEEHHHHCCCCCCCCCHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHH
VLKGLQLTRTLCASLSLGAGDHALRLALGFACERRLYGRTLIDLPNARRTLIDAYTDQLL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHH
AEAAALVGARSIQALPDEMSVTSAVVKYLVPTRAEAMLDTLAELLGARAFLADTYAHGMF
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKVQRDNRIVSLFDGNTLVNLNAIVNAFQTLAKRYRGRDGADAGQALAAFDLGMPLPAFD
HHHHCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCC
RGALSLVSRHGCRVVGALPALADGIAQRAACEPALSRLVAPVRRLATLTDDVHRRMLACP
HHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PVRVHVPVEQFELAKRYALCHAAASALGLWWHTRHRVGEASAAPPWRDGLWLRAVLRRVR
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
VALGDAADFDDEAGDALWRALLRQHRDGLLFSLLPCELAEHRGEAA
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]