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The map label for this gene is ap2140 [C]

Identifier: 126209457

GI number: 126209457

Start: 2228336

End: 2229145

Strand: Reverse

Name: ap2140 [C]

Synonym: APL_2003

Alternate gene names: 126209457

Gene position: 2229145-2228336 (Counterclockwise)

Preceding gene: 126209459

Following gene: 126209456

Centisome position: 98.01

GC content: 40.62

Gene sequence:

>810_bases
ATGAATAAACCTAAACAGCCCATCAAGATTGTATTTTTCGATATCGACGAAACCCTTTATATCAAATCTAAAGCGCATAT
TCCCGAATCGATTACAAAGGAAGTATTACCCCGTTTAAAACAAAAAGGCATTATTACCGCGATTGCCACCGGACGGAATT
TCGGCAGTTTGCCAAAAGCATTAAAACCTTTAATTGACGAACGTTATTTCGAATTATTCGTTACGATCAACGGGCAATAT
AATTTCTATAAAGATCAGCTAATCAGTCAATATGCTTTAACCGCTTCGCAAGTTGAAAGATGTATTGAAAAATTGACCGC
TCTCGGTATTGTTTATGCTTTTGTCAGCCAAGATGAAATCGCCGTATCCGAAGATAATACAATCGTGCATGAGGCGCTTA
GTCCGATTAAAGCGGATTATATTGTTGATCCCGACTATTATTTAACGCATACCGCCGTGCAACTATTGGCTTTCTATCCC
GAATCACGTGATCAAGAAGTTGCAGAAAGCGGTATTTTTGCGGATGACTTAAAAGTATGCCGCTGGCATCCGATGGGAGT
TGATATGCTCAGGAAAGAAAATTCGAAAGCGCGCGGCATAGAAGACGTGATCAAATACTTCGGCTTGAGTATTGAAAATA
CCATGGCGTTCGGCGACGGTTTTAACGATTTGGAGATGTTTGATACCGTCGGGTTCAGCGTAGCAATGGGCAATGCGGAA
CAAGCGTTAAAAACGCGAGCGAATTATGTGACCAAAAATATCGAACAAGACGGTATTCTTTACGCCCTCGAACAACTTGA
AATCATTTAA

Upstream 100 bases:

>100_bases
CGCTTTATGTTTTATCAAATTTAATAAAGAAAAATCGAAGAATTTTTGCGATACGGATCGGAAAAAAGTACAATTCCGAT
TAAATATAAGGAAATAAACT

Downstream 100 bases:

>100_bases
TTTTATTAGGCTATCTAAAAGATAGCTTTTTTATCATATTTTTGTTTTTATAAGAATCATTCTCATATATAATGCACTCA
TTTTTATTTACATAATTTAC

Product: hypothetical protein

Products: NA

Alternate protein names: Phosphatase; Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MNKPKQPIKIVFFDIDETLYIKSKAHIPESITKEVLPRLKQKGIITAIATGRNFGSLPKALKPLIDERYFELFVTINGQY
NFYKDQLISQYALTASQVERCIEKLTALGIVYAFVSQDEIAVSEDNTIVHEALSPIKADYIVDPDYYLTHTAVQLLAFYP
ESRDQEVAESGIFADDLKVCRWHPMGVDMLRKENSKARGIEDVIKYFGLSIENTMAFGDGFNDLEMFDTVGFSVAMGNAE
QALKTRANYVTKNIEQDGILYALEQLEII

Sequences:

>Translated_269_residues
MNKPKQPIKIVFFDIDETLYIKSKAHIPESITKEVLPRLKQKGIITAIATGRNFGSLPKALKPLIDERYFELFVTINGQY
NFYKDQLISQYALTASQVERCIEKLTALGIVYAFVSQDEIAVSEDNTIVHEALSPIKADYIVDPDYYLTHTAVQLLAFYP
ESRDQEVAESGIFADDLKVCRWHPMGVDMLRKENSKARGIEDVIKYFGLSIENTMAFGDGFNDLEMFDTVGFSVAMGNAE
QALKTRANYVTKNIEQDGILYALEQLEII
>Mature_269_residues
MNKPKQPIKIVFFDIDETLYIKSKAHIPESITKEVLPRLKQKGIITAIATGRNFGSLPKALKPLIDERYFELFVTINGQY
NFYKDQLISQYALTASQVERCIEKLTALGIVYAFVSQDEIAVSEDNTIVHEALSPIKADYIVDPDYYLTHTAVQLLAFYP
ESRDQEVAESGIFADDLKVCRWHPMGVDMLRKENSKARGIEDVIKYFGLSIENTMAFGDGFNDLEMFDTVGFSVAMGNAE
QALKTRANYVTKNIEQDGILYALEQLEII

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786982, Length=273, Percent_Identity=27.8388278388278, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI2367265, Length=271, Percent_Identity=26.1992619926199, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR002130 [H]

Pfam domain/function: PF08282 Hydrolase_3; PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 30456; Mature: 30456

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPKQPIKIVFFDIDETLYIKSKAHIPESITKEVLPRLKQKGIITAIATGRNFGSLPKA
CCCCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHH
LKPLIDERYFELFVTINGQYNFYKDQLISQYALTASQVERCIEKLTALGIVYAFVSQDEI
HHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
AVSEDNTIVHEALSPIKADYIVDPDYYLTHTAVQLLAFYPESRDQEVAESGIFADDLKVC
EECCCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHCHHHH
RWHPMGVDMLRKENSKARGIEDVIKYFGLSIENTMAFGDGFNDLEMFDTVGFSVAMGNAE
EECCCCHHHHHHCCCCCCCHHHHHHHHCCCHHHHEECCCCCCHHHHHHHCCCEEEECCHH
QALKTRANYVTKNIEQDGILYALEQLEII
HHHHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNKPKQPIKIVFFDIDETLYIKSKAHIPESITKEVLPRLKQKGIITAIATGRNFGSLPKA
CCCCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHH
LKPLIDERYFELFVTINGQYNFYKDQLISQYALTASQVERCIEKLTALGIVYAFVSQDEI
HHHHHHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
AVSEDNTIVHEALSPIKADYIVDPDYYLTHTAVQLLAFYPESRDQEVAESGIFADDLKVC
EECCCCHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHCHHHH
RWHPMGVDMLRKENSKARGIEDVIKYFGLSIENTMAFGDGFNDLEMFDTVGFSVAMGNAE
EECCCCHHHHHHCCCCCCCHHHHHHHHCCCHHHHEECCCCCCHHHHHHHCCCEEEECCHH
QALKTRANYVTKNIEQDGILYALEQLEII
HHHHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA