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The map label for this gene is corA [H]

Identifier: 126209435

GI number: 126209435

Start: 2208647

End: 2209600

Strand: Reverse

Name: corA [H]

Synonym: APL_1981

Alternate gene names: 126209435

Gene position: 2209600-2208647 (Counterclockwise)

Preceding gene: 126209444

Following gene: 126209434

Centisome position: 97.15

GC content: 44.13

Gene sequence:

>954_bases
ATGATCCGTGCATTTGCTTTAGATAACGCACGTCTTATCAGTGTTGATGAAACCGCAACCGATCAGTTAAACGATGCGAT
TTGGATTGATCTAATCGATCCGAGCGATGACGAACGTAGCGTATTACAACGCGGTTTAGACCAAACGCTTGCCGAAGAAC
ACGAATTGGAAGACTTAGAGGCTTCCGCTCGCTTTTTCGAAGACGAAGACGGCTTACACCTTCACTCTTTTTTCTATTGC
TTAGATGATGACGATTACGCCGATATCGCCACTGTGGCATTTACCATTCGTGACGGGCGTTTATTTACTCTGCGCGAACG
CGATTTACCGGCGTTCCGTTTATATCGAATGCGTTCTCGCCGTGAAAAATTAATTGATAGTAATGCGTACGAATTGTTGC
TCGACTTATTCGAAACCAAAATCGAGCAGCTTGCAGACGTGATCGAAACGATTTATGCGGATTTAGAAACCTTAAGCCGT
GTAATCTTAAACGGTAAGCAAGAAAGCGATAACTTTGACGATGCGCTTTCCGATTTAACCGAATTGGAAGATGCCAGCTC
AAAAGTGCGTTTATGTCTGATGGATACGCAACGTGCGTTAAGTTTCTTATTGCGTAAAACCCGTTTGCCGAATAATCAGC
TTGAACAAGCGCGTGATATTATGCGAGATATCGAATCGCTCCAGCCGCATAACGAATCGCTGTTCCAAAAAGTGAACTTC
TTGATGCAAGCGGCAATGGGTTATATCAATATCGAGCAGAATAAAATTATGAAATTCTTCTCGGTCGTATCGGTAATGTT
CCTCCCGGCAACGCTCGTTGCCTCCACTTACGGGATGAACTTTGAATTTATGCCGGAATTGCATTTTAAATACGGCTACC
CGATGGCAATCGGCTTAATGATTTGCGCCGCCGCCACCCCGTATATCTACTTTAAACGCAAAGGCTGGTTATAA

Upstream 100 bases:

>100_bases
CGCTTGTCCAAACCCTCAGGTTGCCGGCAAGTCGGTAACTCTCGCCTAGTATCTTTTTTGTTCCTTTTTGTTCATTACCT
CCTAACCATTGGAGAATAAA

Downstream 100 bases:

>100_bases
AAAGCCAAAAGCACAGAATATAAGTTCTGTGCTTTTTTGTTAGCTGTAAGCGATCAGGTTTATCCGGAAATTGGTGTAAT
AGACAAATTTGTTGCTAAAA

Product: magnesium/nickel/cobalt transporter CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MIRAFALDNARLISVDETATDQLNDAIWIDLIDPSDDERSVLQRGLDQTLAEEHELEDLEASARFFEDEDGLHLHSFFYC
LDDDDYADIATVAFTIRDGRLFTLRERDLPAFRLYRMRSRREKLIDSNAYELLLDLFETKIEQLADVIETIYADLETLSR
VILNGKQESDNFDDALSDLTELEDASSKVRLCLMDTQRALSFLLRKTRLPNNQLEQARDIMRDIESLQPHNESLFQKVNF
LMQAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFEFMPELHFKYGYPMAIGLMICAAATPYIYFKRKGWL

Sequences:

>Translated_317_residues
MIRAFALDNARLISVDETATDQLNDAIWIDLIDPSDDERSVLQRGLDQTLAEEHELEDLEASARFFEDEDGLHLHSFFYC
LDDDDYADIATVAFTIRDGRLFTLRERDLPAFRLYRMRSRREKLIDSNAYELLLDLFETKIEQLADVIETIYADLETLSR
VILNGKQESDNFDDALSDLTELEDASSKVRLCLMDTQRALSFLLRKTRLPNNQLEQARDIMRDIESLQPHNESLFQKVNF
LMQAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFEFMPELHFKYGYPMAIGLMICAAATPYIYFKRKGWL
>Mature_317_residues
MIRAFALDNARLISVDETATDQLNDAIWIDLIDPSDDERSVLQRGLDQTLAEEHELEDLEASARFFEDEDGLHLHSFFYC
LDDDDYADIATVAFTIRDGRLFTLRERDLPAFRLYRMRSRREKLIDSNAYELLLDLFETKIEQLADVIETIYADLETLSR
VILNGKQESDNFDDALSDLTELEDASSKVRLCLMDTQRALSFLLRKTRLPNNQLEQARDIMRDIESLQPHNESLFQKVNF
LMQAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFEFMPELHFKYGYPMAIGLMICAAATPYIYFKRKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=317, Percent_Identity=69.7160883280757, Blast_Score=453, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36760; Mature: 36760

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRAFALDNARLISVDETATDQLNDAIWIDLIDPSDDERSVLQRGLDQTLAEEHELEDLE
CEEEEEECCCEEEEECCHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
ASARFFEDEDGLHLHSFFYCLDDDDYADIATVAFTIRDGRLFTLRERDLPAFRLYRMRSR
HHHHHCCCCCCCEEEHEEEEECCCCCCCCEEEEEEEECCEEEEEECCCCCHHHHHHHHHH
REKLIDSNAYELLLDLFETKIEQLADVIETIYADLETLSRVILNGKQESDNFDDALSDLT
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
ELEDASSKVRLCLMDTQRALSFLLRKTRLPNNQLEQARDIMRDIESLQPHNESLFQKVNF
HHHCCCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LMQAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFEFMPELHFKYGYPMAIGLM
HHHHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHCCCCCHHHHHHH
ICAAATPYIYFKRKGWL
HHHHCCCEEEEECCCCC
>Mature Secondary Structure
MIRAFALDNARLISVDETATDQLNDAIWIDLIDPSDDERSVLQRGLDQTLAEEHELEDLE
CEEEEEECCCEEEEECCHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
ASARFFEDEDGLHLHSFFYCLDDDDYADIATVAFTIRDGRLFTLRERDLPAFRLYRMRSR
HHHHHCCCCCCCEEEHEEEEECCCCCCCCEEEEEEEECCEEEEEECCCCCHHHHHHHHHH
REKLIDSNAYELLLDLFETKIEQLADVIETIYADLETLSRVILNGKQESDNFDDALSDLT
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
ELEDASSKVRLCLMDTQRALSFLLRKTRLPNNQLEQARDIMRDIESLQPHNESLFQKVNF
HHHCCCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LMQAAMGYINIEQNKIMKFFSVVSVMFLPATLVASTYGMNFEFMPELHFKYGYPMAIGLM
HHHHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHCCCCCHHHHHHH
ICAAATPYIYFKRKGWL
HHHHCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA