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The map label for this gene is argD [H]

Identifier: 126209428

GI number: 126209428

Start: 2200641

End: 2201936

Strand: Direct

Name: argD [H]

Synonym: APL_1974

Alternate gene names: 126209428

Gene position: 2200641-2201936 (Clockwise)

Preceding gene: 126209427

Following gene: 126209429

Centisome position: 96.75

GC content: 45.29

Gene sequence:

>1296_bases
ATGGAATCAAATGTGCGTAGTTACCCTCGTAAGCTACCGTTTGCGTACCAAAAAGCACAAGGTGTTTGGGTAACGGATGT
TGAAGGTAATGAATATCTTGATTTTTTAGCTGGTGCAGGAACTCTTGCATTAGGTCATAATCACCCGGTATTAATGCAAT
CAATCAAAGACGTATTGGACAGCGGTTTACCATTACATACGCTCGACTTAACCACTCCGTTAAAAGACGCATTCACGGAA
GAATTGCTTTCATTCTTCCCGAAAGATCAATATATCCTTCAATTTACCGGTCCATCAGGTGCGGACGCTAACGAAGCGGC
AATCAAATTGGCAAAAACTTATACCGGTCGCGGTAATGTGATCGCATTCTCCGGCGGCTTCCACGGTATGACGCACGGTG
CGTTATCATTAACCGGTAACCTAAGCGCGAAAAATGCGGTACAAAACTTAATGGCTGGCGTGCAATTTATGCCGTATCCG
CATGAATATCGTTGCCCGTTCGGTATCGGCGGCGAAGTGGGTGCAAAAGCGGTTGAACACTATTTCGAAAACTTTATCGA
AGATGTGGAAAGCGGTGTAGTAAAACCGGCAGCGGTAATTTTAGAAGCGATCCAAGGCGAGGGCGGCGTGGTGCCAGCTC
CGATCAGCTTCTTACAAAAAGTGCGTGAAGTGACCCAAAAACACGGTATTTTAATGATTGTTGATGAAGTTCAAGCTGGT
TTCTGCCGTAGCGGTAAAATGTTTGCGTTCGAACACGCAGGCATTGAACCTGATGTAGTAGTAATGTCAAAAGCGGTCGG
CGGTTCGTTACCGTTAGCGGTATTAGCAATTCGTAAAGAATTTGACGCATGGCAGCCGGCGGGTCATACCGGTACTTTCC
GTGGTAACCAATTAGCAATGGCGACCGGTTATGCTTCATTAAAAATTATGCGTGAAGAAAATTTAGCGCAAAATGCACAA
GAACGTGGCGAATACTTAACTAACGCATTACGTGAATTAAGCAAAGAATTCCCATGTATCGGTAATGTACGTGGTCGCGG
CTTAATGATGGGTATCGATATCGTTGATGAGCGTAAACCACAAGATGCAACCGGCGCTTACCCACAAGACGGTGAATTAG
CGGTCGCAATTCAAAAAGCGTGTTTCAACAATAAATTATTGTTAGAACGTGGCGGCCGTGGTGGTAATGTGGTGCGTGTA
CTTTGTGCGGTAAACATCAACCAAGCGGAATGTGAAGAGTTTATCAAACGCTTCAAACAATCTGTCGCAGACGCATTAAA
AGCGGTGCGTGGTTAA

Upstream 100 bases:

>100_bases
TTTTCACCTCTTTTAGAAGGTTTATTTTAACATGACAATTAAAACGCCTGTTCAAGCAGTTCTTGCTTCCAACCAATACT
TTTTAGATCGCCAAGATGCA

Downstream 100 bases:

>100_bases
TTTTAACCCTACACGAGCCGTGTAGGGTTGCTTTATTTGAGCCACGCTGTGGCTCTTTTTATATCCTAGCTCCAACGGGG
CTGAGTTTAATTAACCTAGC

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MESNVRSYPRKLPFAYQKAQGVWVTDVEGNEYLDFLAGAGTLALGHNHPVLMQSIKDVLDSGLPLHTLDLTTPLKDAFTE
ELLSFFPKDQYILQFTGPSGADANEAAIKLAKTYTGRGNVIAFSGGFHGMTHGALSLTGNLSAKNAVQNLMAGVQFMPYP
HEYRCPFGIGGEVGAKAVEHYFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISFLQKVREVTQKHGILMIVDEVQAG
FCRSGKMFAFEHAGIEPDVVVMSKAVGGSLPLAVLAIRKEFDAWQPAGHTGTFRGNQLAMATGYASLKIMREENLAQNAQ
ERGEYLTNALRELSKEFPCIGNVRGRGLMMGIDIVDERKPQDATGAYPQDGELAVAIQKACFNNKLLLERGGRGGNVVRV
LCAVNINQAECEEFIKRFKQSVADALKAVRG

Sequences:

>Translated_431_residues
MESNVRSYPRKLPFAYQKAQGVWVTDVEGNEYLDFLAGAGTLALGHNHPVLMQSIKDVLDSGLPLHTLDLTTPLKDAFTE
ELLSFFPKDQYILQFTGPSGADANEAAIKLAKTYTGRGNVIAFSGGFHGMTHGALSLTGNLSAKNAVQNLMAGVQFMPYP
HEYRCPFGIGGEVGAKAVEHYFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISFLQKVREVTQKHGILMIVDEVQAG
FCRSGKMFAFEHAGIEPDVVVMSKAVGGSLPLAVLAIRKEFDAWQPAGHTGTFRGNQLAMATGYASLKIMREENLAQNAQ
ERGEYLTNALRELSKEFPCIGNVRGRGLMMGIDIVDERKPQDATGAYPQDGELAVAIQKACFNNKLLLERGGRGGNVVRV
LCAVNINQAECEEFIKRFKQSVADALKAVRG
>Mature_431_residues
MESNVRSYPRKLPFAYQKAQGVWVTDVEGNEYLDFLAGAGTLALGHNHPVLMQSIKDVLDSGLPLHTLDLTTPLKDAFTE
ELLSFFPKDQYILQFTGPSGADANEAAIKLAKTYTGRGNVIAFSGGFHGMTHGALSLTGNLSAKNAVQNLMAGVQFMPYP
HEYRCPFGIGGEVGAKAVEHYFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISFLQKVREVTQKHGILMIVDEVQAG
FCRSGKMFAFEHAGIEPDVVVMSKAVGGSLPLAVLAIRKEFDAWQPAGHTGTFRGNQLAMATGYASLKIMREENLAQNAQ
ERGEYLTNALRELSKEFPCIGNVRGRGLMMGIDIVDERKPQDATGAYPQDGELAVAIQKACFNNKLLLERGGRGGNVVRV
LCAVNINQAECEEFIKRFKQSVADALKAVRG

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=443, Percent_Identity=30.0225733634311, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI4557809, Length=426, Percent_Identity=28.6384976525822, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI24119277, Length=447, Percent_Identity=26.3982102908277, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI37574042, Length=399, Percent_Identity=29.5739348370927, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI226442705, Length=398, Percent_Identity=28.894472361809, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI226442709, Length=331, Percent_Identity=31.1178247734139, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI284507298, Length=339, Percent_Identity=29.2035398230088, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI188536080, Length=384, Percent_Identity=27.8645833333333, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI38679950, Length=384, Percent_Identity=27.8645833333333, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI38679946, Length=384, Percent_Identity=27.8645833333333, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1787560, Length=419, Percent_Identity=35.799522673031, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1789016, Length=440, Percent_Identity=31.8181818181818, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI145693181, Length=409, Percent_Identity=32.518337408313, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI1789759, Length=419, Percent_Identity=27.6849642004773, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788044, Length=434, Percent_Identity=29.0322580645161, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786349, Length=348, Percent_Identity=27.8735632183908, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786991, Length=321, Percent_Identity=28.9719626168224, Blast_Score=98, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=32.1759259259259, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI71992977, Length=423, Percent_Identity=29.3144208037825, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI25144271, Length=430, Percent_Identity=30.4651162790698, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI25144274, Length=233, Percent_Identity=32.1888412017167, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17541228, Length=381, Percent_Identity=26.246719160105, Blast_Score=95, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6323470, Length=375, Percent_Identity=32.2666666666667, Blast_Score=162, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6324432, Length=413, Percent_Identity=28.8135593220339, Blast_Score=148, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6321456, Length=371, Percent_Identity=29.1105121293801, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI28574759, Length=437, Percent_Identity=29.9771167048055, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI161085790, Length=446, Percent_Identity=30.2690582959641, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI21357415, Length=423, Percent_Identity=27.4231678486998, Blast_Score=151, Evalue=8e-37,
Organism=Drosophila melanogaster, GI21356575, Length=437, Percent_Identity=26.7734553775744, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI281366494, Length=392, Percent_Identity=28.5714285714286, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24667139, Length=392, Percent_Identity=28.5714285714286, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24667143, Length=392, Percent_Identity=28.5714285714286, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 46678; Mature: 46678

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESNVRSYPRKLPFAYQKAQGVWVTDVEGNEYLDFLAGAGTLALGHNHPVLMQSIKDVLD
CCCCHHHHHHHCCCHHHHCCCEEEEECCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHH
SGLPLHTLDLTTPLKDAFTEELLSFFPKDQYILQFTGPSGADANEAAIKLAKTYTGRGNV
CCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHEECCCCCE
IAFSGGFHGMTHGALSLTGNLSAKNAVQNLMAGVQFMPYPHEYRCPFGIGGEVGAKAVEH
EEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCEECCCCCCCCCCCCCCCHHHHHHHHH
YFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISFLQKVREVTQKHGILMIVDEVQAG
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCC
FCRSGKMFAFEHAGIEPDVVVMSKAVGGSLPLAVLAIRKEFDAWQPAGHTGTFRGNQLAM
CCCCCCEEEEECCCCCCCCEEEEHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
ATGYASLKIMREENLAQNAQERGEYLTNALRELSKEFPCIGNVRGRGLMMGIDIVDERKP
EECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCC
QDATGAYPQDGELAVAIQKACFNNKLLLERGGRGGNVVRVLCAVNINQAECEEFIKRFKQ
CCCCCCCCCCCCEEEEEEHHHCCCCEEEECCCCCCCEEEEEEEECCCHHHHHHHHHHHHH
SVADALKAVRG
HHHHHHHHHCC
>Mature Secondary Structure
MESNVRSYPRKLPFAYQKAQGVWVTDVEGNEYLDFLAGAGTLALGHNHPVLMQSIKDVLD
CCCCHHHHHHHCCCHHHHCCCEEEEECCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHH
SGLPLHTLDLTTPLKDAFTEELLSFFPKDQYILQFTGPSGADANEAAIKLAKTYTGRGNV
CCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHEECCCCCE
IAFSGGFHGMTHGALSLTGNLSAKNAVQNLMAGVQFMPYPHEYRCPFGIGGEVGAKAVEH
EEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCEECCCCCCCCCCCCCCCHHHHHHHHH
YFENFIEDVESGVVKPAAVILEAIQGEGGVVPAPISFLQKVREVTQKHGILMIVDEVQAG
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCC
FCRSGKMFAFEHAGIEPDVVVMSKAVGGSLPLAVLAIRKEFDAWQPAGHTGTFRGNQLAM
CCCCCCEEEEECCCCCCCCEEEEHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEE
ATGYASLKIMREENLAQNAQERGEYLTNALRELSKEFPCIGNVRGRGLMMGIDIVDERKP
EECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCC
QDATGAYPQDGELAVAIQKACFNNKLLLERGGRGGNVVRVLCAVNINQAECEEFIKRFKQ
CCCCCCCCCCCCEEEEEEHHHCCCCEEEECCCCCCCEEEEEEEECCCHHHHHHHHHHHHH
SVADALKAVRG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]