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The map label for this gene is xylH [H]

Identifier: 126209371

GI number: 126209371

Start: 2144526

End: 2145653

Strand: Direct

Name: xylH [H]

Synonym: APL_1911

Alternate gene names: 126209371

Gene position: 2144526-2145653 (Clockwise)

Preceding gene: 126209370

Following gene: 126209372

Centisome position: 94.29

GC content: 44.06

Gene sequence:

>1128_bases
ATGTTGAAGCTAAAATCTGTCAATTTACAAGTTTATATTATGCTCATTGCTATTGTTGTGATTATGAGCTTTTTCTCGGT
AGCAACCGACGGTGCCTATTTAAGCGCACGTAATATTTCAAACTTATTACGCCAAACCTCCATTACCGGGATTTTAGCGA
TCGGGATGGTATTTGTGATTATCTCGGCGGAAATTGACCTATCCGTCGGTTCATTAATGGGGTTATTAGGCGGATTCGCC
GCTATCGCCGACGTTTGGTGGGGCTGGTCTTTACCGCTTACTATTGCGGTAACACTTGTGCTAGGTACATTATTAGGTGC
TTGGAACGGTTGGTGGGTCTCTTATCGTAAAGTACCGTCCTTTATCGTCACCTTAGCGGGGATGTTAGCCTTCCGCGGTA
TTTTAATCGGCTTAACCAACGGTACGACCGTTTCACCGATTAGTAATGATATGACCGCTATCGGTCAAGGCTATATTCCG
GATGTTACCGGTATGATTCTCGGTTTAGTGGCGGTATTCTGTTTCGTTACTTGGGGGACTTATCAACGTAAAGCGCGTAA
AAACTTAAACTTGAATGTGCCTGATGCGACGAAAGACATTATGAAATACGGCTTATTTGCTATCTGTGTCTTAGGTGCGA
TTTACTTATTGAACGATTATCGCGGTATCCCGTTCCCTGTACTGGTATTAGCGATTTTAACCGTGGTCGGTATGTTTATC
GCACGTAAAACCGCATTTGGTCGCCATATTTATGCCATCGGCGGTAATATTGAGGCGGCAAGACTTTCAGGGATTAACGT
TGAAAAAGTAAAATTAACCATTTTCGCAATCAACGGTTTTATGGTAGCGATTGCCGGTTTAATCCTTAGTGCGCGTTTAG
GTGCGGGGGCGCCGTCTGCAGGTCAAAATGCGGAGCTGGATGCGATTGCGGCTTGTGTCATCGGCGGGGTAAGTTTAGCC
GGCGGTATCGGTAGCGTATATGGCGTTATTATCGGTGCCTTTATTATCGCTTTACTTGATAACGGTATGAGTATGTTAGA
CGTGCCGACTTTCTGGCAATATATCGTAAAAGGTGCGATTCTATTATTAGCGGTTTGGGTCGATACTATGAGTAAGAAAA
AAATGTAA

Upstream 100 bases:

>100_bases
TAGAGTTCTGGTTATGCACCAAGGACAAATTAAAGCAGACTTAATTAACGATAATTTGACGCAAGAGCAAGTTATGGAAG
CCGCACTCAAGGAGTAACCT

Downstream 100 bases:

>100_bases
TCCTCATTCCGACGATTAATTCTTTAGCAAGCACTCAATATTCTTAGGAAATATTGAGTGCTTTTTTCATAACTACGCAA
AATGTGGTATGTTAGCGCGA

Product: xylose transport system permease protein xylH

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MLKLKSVNLQVYIMLIAIVVIMSFFSVATDGAYLSARNISNLLRQTSITGILAIGMVFVIISAEIDLSVGSLMGLLGGFA
AIADVWWGWSLPLTIAVTLVLGTLLGAWNGWWVSYRKVPSFIVTLAGMLAFRGILIGLTNGTTVSPISNDMTAIGQGYIP
DVTGMILGLVAVFCFVTWGTYQRKARKNLNLNVPDATKDIMKYGLFAICVLGAIYLLNDYRGIPFPVLVLAILTVVGMFI
ARKTAFGRHIYAIGGNIEAARLSGINVEKVKLTIFAINGFMVAIAGLILSARLGAGAPSAGQNAELDAIAACVIGGVSLA
GGIGSVYGVIIGAFIIALLDNGMSMLDVPTFWQYIVKGAILLLAVWVDTMSKKKM

Sequences:

>Translated_375_residues
MLKLKSVNLQVYIMLIAIVVIMSFFSVATDGAYLSARNISNLLRQTSITGILAIGMVFVIISAEIDLSVGSLMGLLGGFA
AIADVWWGWSLPLTIAVTLVLGTLLGAWNGWWVSYRKVPSFIVTLAGMLAFRGILIGLTNGTTVSPISNDMTAIGQGYIP
DVTGMILGLVAVFCFVTWGTYQRKARKNLNLNVPDATKDIMKYGLFAICVLGAIYLLNDYRGIPFPVLVLAILTVVGMFI
ARKTAFGRHIYAIGGNIEAARLSGINVEKVKLTIFAINGFMVAIAGLILSARLGAGAPSAGQNAELDAIAACVIGGVSLA
GGIGSVYGVIIGAFIIALLDNGMSMLDVPTFWQYIVKGAILLLAVWVDTMSKKKM
>Mature_375_residues
MLKLKSVNLQVYIMLIAIVVIMSFFSVATDGAYLSARNISNLLRQTSITGILAIGMVFVIISAEIDLSVGSLMGLLGGFA
AIADVWWGWSLPLTIAVTLVLGTLLGAWNGWWVSYRKVPSFIVTLAGMLAFRGILIGLTNGTTVSPISNDMTAIGQGYIP
DVTGMILGLVAVFCFVTWGTYQRKARKNLNLNVPDATKDIMKYGLFAICVLGAIYLLNDYRGIPFPVLVLAILTVVGMFI
ARKTAFGRHIYAIGGNIEAARLSGINVEKVKLTIFAINGFMVAIAGLILSARLGAGAPSAGQNAELDAIAACVIGGVSLA
GGIGSVYGVIIGAFIIALLDNGMSMLDVPTFWQYIVKGAILLLAVWVDTMSKKKM

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=371, Percent_Identity=72.7762803234501, Blast_Score=496, Evalue=1e-142,
Organism=Escherichia coli, GI1790191, Length=360, Percent_Identity=36.6666666666667, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1788896, Length=381, Percent_Identity=30.4461942257218, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI145693152, Length=156, Percent_Identity=44.8717948717949, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1790524, Length=152, Percent_Identity=40.7894736842105, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788471, Length=380, Percent_Identity=29.2105263157895, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787793, Length=120, Percent_Identity=39.1666666666667, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87082395, Length=115, Percent_Identity=40.8695652173913, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI145693214, Length=313, Percent_Identity=30.3514376996805, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787794, Length=156, Percent_Identity=28.8461538461538, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 39824; Mature: 39824

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLKSVNLQVYIMLIAIVVIMSFFSVATDGAYLSARNISNLLRQTSITGILAIGMVFVI
CCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
ISAEIDLSVGSLMGLLGGFAAIADVWWGWSLPLTIAVTLVLGTLLGAWNGWWVSYRKVPS
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FIVTLAGMLAFRGILIGLTNGTTVSPISNDMTAIGQGYIPDVTGMILGLVAVFCFVTWGT
HHHHHHHHHHHHHHHEECCCCCEECCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCH
YQRKARKNLNLNVPDATKDIMKYGLFAICVLGAIYLLNDYRGIPFPVLVLAILTVVGMFI
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
ARKTAFGRHIYAIGGNIEAARLSGINVEKVKLTIFAINGFMVAIAGLILSARLGAGAPSA
HHHHHCCCEEEEECCCCEEHEECCCCEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCC
GQNAELDAIAACVIGGVSLAGGIGSVYGVIIGAFIIALLDNGMSMLDVPTFWQYIVKGAI
CCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LLLAVWVDTMSKKKM
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKLKSVNLQVYIMLIAIVVIMSFFSVATDGAYLSARNISNLLRQTSITGILAIGMVFVI
CCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHH
ISAEIDLSVGSLMGLLGGFAAIADVWWGWSLPLTIAVTLVLGTLLGAWNGWWVSYRKVPS
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FIVTLAGMLAFRGILIGLTNGTTVSPISNDMTAIGQGYIPDVTGMILGLVAVFCFVTWGT
HHHHHHHHHHHHHHHEECCCCCEECCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCH
YQRKARKNLNLNVPDATKDIMKYGLFAICVLGAIYLLNDYRGIPFPVLVLAILTVVGMFI
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
ARKTAFGRHIYAIGGNIEAARLSGINVEKVKLTIFAINGFMVAIAGLILSARLGAGAPSA
HHHHHCCCEEEEECCCCEEHEECCCCEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCC
GQNAELDAIAACVIGGVSLAGGIGSVYGVIIGAFIIALLDNGMSMLDVPTFWQYIVKGAI
CCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LLLAVWVDTMSKKKM
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]