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The map label for this gene is yfiC [C]

Identifier: 126209360

GI number: 126209360

Start: 2130775

End: 2131485

Strand: Direct

Name: yfiC [C]

Synonym: APL_1900

Alternate gene names: 126209360

Gene position: 2130775-2131485 (Clockwise)

Preceding gene: 126209351

Following gene: 126209362

Centisome position: 93.68

GC content: 43.88

Gene sequence:

>711_bases
ATGACAAAATCTCAAGGTTTCCAATTTAAACAATTTTTTATCGCTCATGACAAATGCGCGATGAAAGTCAATACCGACGG
CATCTTACTCGGTGCTATCGCCGATATTCGGCACAAACGTCAGATCTTAGATCTCGGCACCGGTACCGGATTAGTGGCAA
TTATGTTGGCACAGCGCACGGACGAAAATACGCAAATTAGCGCGCTTGAATTAGAGCCGAACGCCTATCGACAAGCGGTT
GAAAATTGCCGAAATTCCGCATTTTCCGACCGCTTGCAAGTTTATCAAGGCGATGTCTTAGATTATCACTTTCACCAAAA
GTTTGATCTTATCGTGTCGAACCCGCCTTATTTCAGCGAGAGTTTGGCTTCCCGATCTTATGAAAGAGATTTGGCTCGTG
CCGCGACCCAAAGCCATTTAGACTGGCTGTTACAAGCGAAAAAATGGTTGGCGGAACAGGGTGAAATCAGCTTTATTTTA
CCCTTTGAAGCGGCGGAAAAATTAGTGGAACAAAGCCGAACAAGCTGTCTGTTTTGCACGAAAATTTGCAAAATCATTAC
CAAACAAGGGCAAGCGGCGAAACGTATGATCGTCAGTTTTTCAGCGCAAAACGTACCGCTTGAGGAACAGGAATTAGTGA
TTTACGATGCGGATAATCAATATACCGAAGCGTTCAAGCAGCTAACCAAGGCGTTTTATTTAAATATGTAG

Upstream 100 bases:

>100_bases
ACCAGCTGGTACGTTTTCTAAGCCCATTTTAGTTTCCTTCTGTTGTAGAGGTAAAAAAACAATGCGATTATAGCGTATCT
CACATTAAATTTGTACATCT

Downstream 100 bases:

>100_bases
CCAAACAAAAAACCGACCAAGCGGTCGGTTTTCTATATTCGATGGGTTACTCTTCCAATTCTGCTAAATCCAGCAATTCC
GGCGAAAGAATAATGCCGGT

Product: hypothetical protein

Products: NA

Alternate protein names: tRNA m6A37 methyltransferase

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MTKSQGFQFKQFFIAHDKCAMKVNTDGILLGAIADIRHKRQILDLGTGTGLVAIMLAQRTDENTQISALELEPNAYRQAV
ENCRNSAFSDRLQVYQGDVLDYHFHQKFDLIVSNPPYFSESLASRSYERDLARAATQSHLDWLLQAKKWLAEQGEISFIL
PFEAAEKLVEQSRTSCLFCTKICKIITKQGQAAKRMIVSFSAQNVPLEEQELVIYDADNQYTEAFKQLTKAFYLNM

Sequences:

>Translated_236_residues
MTKSQGFQFKQFFIAHDKCAMKVNTDGILLGAIADIRHKRQILDLGTGTGLVAIMLAQRTDENTQISALELEPNAYRQAV
ENCRNSAFSDRLQVYQGDVLDYHFHQKFDLIVSNPPYFSESLASRSYERDLARAATQSHLDWLLQAKKWLAEQGEISFIL
PFEAAEKLVEQSRTSCLFCTKICKIITKQGQAAKRMIVSFSAQNVPLEEQELVIYDADNQYTEAFKQLTKAFYLNM
>Mature_235_residues
TKSQGFQFKQFFIAHDKCAMKVNTDGILLGAIADIRHKRQILDLGTGTGLVAIMLAQRTDENTQISALELEPNAYRQAVE
NCRNSAFSDRLQVYQGDVLDYHFHQKFDLIVSNPPYFSESLASRSYERDLARAATQSHLDWLLQAKKWLAEQGEISFILP
FEAAEKLVEQSRTSCLFCTKICKIITKQGQAAKRMIVSFSAQNVPLEEQELVIYDADNQYTEAFKQLTKAFYLNM

Specific function: Specifically methylates the adenine in position 37 of tRNA(Val)

COG id: COG4123

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family

Homologues:

Organism=Escherichia coli, GI87082131, Length=237, Percent_Identity=38.8185654008439, Blast_Score=171, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRMN6_ACTP2 (A3N3J4)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054585.1
- ProteinModelPortal:   A3N3J4
- SMR:   A3N3J4
- STRING:   A3N3J4
- GeneID:   4849626
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1900
- eggNOG:   COG4123
- HOGENOM:   HBG307609
- OMA:   FKQFHIN
- PhylomeDB:   A3N3J4
- ProtClustDB:   CLSK2322355
- BioCyc:   APLE416269:APL_1900-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01872
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR007848
- InterPro:   IPR022882
- PRINTS:   PR00507

Pfam domain/function: PF05175 MTS

EC number: =2.1.1.55

Molecular weight: Translated: 26906; Mature: 26775

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSQGFQFKQFFIAHDKCAMKVNTDGILLGAIADIRHKRQILDLGTGTGLVAIMLAQRT
CCCCCCCHHHHHEEECCCEEEEECCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
DENTQISALELEPNAYRQAVENCRNSAFSDRLQVYQGDVLDYHFHQKFDLIVSNPPYFSE
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCHHH
SLASRSYERDLARAATQSHLDWLLQAKKWLAEQGEISFILPFEAAEKLVEQSRTSCLFCT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCHHHHHH
KICKIITKQGQAAKRMIVSFSAQNVPLEEQELVIYDADNQYTEAFKQLTKAFYLNM
HHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKSQGFQFKQFFIAHDKCAMKVNTDGILLGAIADIRHKRQILDLGTGTGLVAIMLAQRT
CCCCCCHHHHHEEECCCEEEEECCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
DENTQISALELEPNAYRQAVENCRNSAFSDRLQVYQGDVLDYHFHQKFDLIVSNPPYFSE
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCHHH
SLASRSYERDLARAATQSHLDWLLQAKKWLAEQGEISFILPFEAAEKLVEQSRTSCLFCT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCHHHHHH
KICKIITKQGQAAKRMIVSFSAQNVPLEEQELVIYDADNQYTEAFKQLTKAFYLNM
HHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA