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The map label for this gene is dapD [H]

Identifier: 126209323

GI number: 126209323

Start: 2092166

End: 2092990

Strand: Direct

Name: dapD [H]

Synonym: APL_1861

Alternate gene names: 126209323

Gene position: 2092166-2092990 (Clockwise)

Preceding gene: 126209322

Following gene: 126209324

Centisome position: 91.98

GC content: 44.48

Gene sequence:

>825_bases
ATGTCTTTACAAGCAATTATCGAAGCGGCATTTGAGCGTCGTGCTGAAATCACACCAAAAACAGTTGATGCAGAAACTCG
TGCTGCAATCGAAGAAGTTATCGAAGGTTTAGATAGCGGTAAATATCGTGTAGCAGAAAAAATTGACGGTGAGTGGGTAA
CTCATCAGTGGTTAAAAAAAGCGGTTTTACTTTCATTCCGTATCAATGACAACCAAATTATTGACGGTGCGGAAACCAAA
TATTACGACAAAGTTGCATTAAAATTTGCCGATTACACCGAAGAACGTTTTGCACAAGAAGGTTTCCGTGTAGTACCGTC
TGCAACCGTACGTAAAGGCGCATACATTTCTAAAAACTGCGTATTAATGCCGTCTTATGTAAACATCGGCGCATACGTAG
GCGAAGGTACAATGGTGGACACTTGGGCAACCGTAGGTTCATGCGCACAAATCGGTAAAAACGTTCACTTATCAGGCGGC
GTAGGTATCGGCGGCGTATTAGAGCCGTTACAAGCAAACCCGACGATTATCGGCGACAACTGCTTTATCGGCGCACGTTC
GGAAGTGGTTGAAGGCGTCATCGTAGAAGACGGTTGTGTAATCTCAATGGGCGTATTTATCGGTCAATCAACCCGTATTT
ATGACCGTGAAACCGGCGAAATCCACTACGGTCGCGTACCGGCGGGTTCTGTGGTTGTTTCCGGTAGCCTTCCGTCAAAA
TGCGGTAAATACAGCCTATATTGTGCGGTTATCGTGAAAAAAGTTGATGCGAAAACTTTAGGTAAAGTGGGTATCAACGA
ATTACTTCGTACCATCGAAGAGTAA

Upstream 100 bases:

>100_bases
ACCGATTGCCTTTTTTCTAGTAGCAAAAAACGGCTATTTATGTTAAAAATTGAAGCCGATTTTCTCTCATAATTTCCATT
TACATTAAAGGAACACAACA

Downstream 100 bases:

>100_bases
TTAAATCCTTCTGCCCCCTCCTTGCAAAAGAGGGGGATTTTTTTACCGCTTGTAAGGAATCAATATGAAAAAAATTCTTC
TGTTAAACGGCCCTAATTTA

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSLQAIIEAAFERRAEITPKTVDAETRAAIEEVIEGLDSGKYRVAEKIDGEWVTHQWLKKAVLLSFRINDNQIIDGAETK
YYDKVALKFADYTEERFAQEGFRVVPSATVRKGAYISKNCVLMPSYVNIGAYVGEGTMVDTWATVGSCAQIGKNVHLSGG
VGIGGVLEPLQANPTIIGDNCFIGARSEVVEGVIVEDGCVISMGVFIGQSTRIYDRETGEIHYGRVPAGSVVVSGSLPSK
CGKYSLYCAVIVKKVDAKTLGKVGINELLRTIEE

Sequences:

>Translated_274_residues
MSLQAIIEAAFERRAEITPKTVDAETRAAIEEVIEGLDSGKYRVAEKIDGEWVTHQWLKKAVLLSFRINDNQIIDGAETK
YYDKVALKFADYTEERFAQEGFRVVPSATVRKGAYISKNCVLMPSYVNIGAYVGEGTMVDTWATVGSCAQIGKNVHLSGG
VGIGGVLEPLQANPTIIGDNCFIGARSEVVEGVIVEDGCVISMGVFIGQSTRIYDRETGEIHYGRVPAGSVVVSGSLPSK
CGKYSLYCAVIVKKVDAKTLGKVGINELLRTIEE
>Mature_273_residues
SLQAIIEAAFERRAEITPKTVDAETRAAIEEVIEGLDSGKYRVAEKIDGEWVTHQWLKKAVLLSFRINDNQIIDGAETKY
YDKVALKFADYTEERFAQEGFRVVPSATVRKGAYISKNCVLMPSYVNIGAYVGEGTMVDTWATVGSCAQIGKNVHLSGGV
GIGGVLEPLQANPTIIGDNCFIGARSEVVEGVIVEDGCVISMGVFIGQSTRIYDRETGEIHYGRVPAGSVVVSGSLPSKC
GKYSLYCAVIVKKVDAKTLGKVGINELLRTIEE

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786362, Length=271, Percent_Identity=84.1328413284133, Blast_Score=448, Evalue=1e-127,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.117 [H]

Molecular weight: Translated: 29692; Mature: 29561

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQAIIEAAFERRAEITPKTVDAETRAAIEEVIEGLDSGKYRVAEKIDGEWVTHQWLKK
CCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHCCCCHHHHHHHHH
AVLLSFRINDNQIIDGAETKYYDKVALKFADYTEERFAQEGFRVVPSATVRKGAYISKNC
HEEEEEEECCCEEECCCCHHHHHHHHEEHHHHHHHHHHHCCCEECCCCHHHCCCEECCCC
VLMPSYVNIGAYVGEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIGDN
EEECCHHCCEEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHCCCCCCCCEEECCC
CFIGARSEVVEGVIVEDGCVISMGVFIGQSTRIYDRETGEIHYGRVPAGSVVVSGSLPSK
EEECCHHHHHCEEEECCCCEEEEHEEECCCCEEEECCCCCEEECCCCCCCEEEECCCCCC
CGKYSLYCAVIVKKVDAKTLGKVGINELLRTIEE
CCCCEEEHHHHHHHHCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLQAIIEAAFERRAEITPKTVDAETRAAIEEVIEGLDSGKYRVAEKIDGEWVTHQWLKK
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHCCCCHHHHHHHHH
AVLLSFRINDNQIIDGAETKYYDKVALKFADYTEERFAQEGFRVVPSATVRKGAYISKNC
HEEEEEEECCCEEECCCCHHHHHHHHEEHHHHHHHHHHHCCCEECCCCHHHCCCEECCCC
VLMPSYVNIGAYVGEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIGDN
EEECCHHCCEEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHCCCCCCCCEEECCC
CFIGARSEVVEGVIVEDGCVISMGVFIGQSTRIYDRETGEIHYGRVPAGSVVVSGSLPSK
EEECCHHHHHCEEEECCCCEEEEHEEECCCCEEEECCCCCEEECCCCCCCEEEECCCCCC
CGKYSLYCAVIVKKVDAKTLGKVGINELLRTIEE
CCCCEEEHHHHHHHHCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA