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The map label for this gene is murB [H]

Identifier: 126209313

GI number: 126209313

Start: 2081993

End: 2083027

Strand: Reverse

Name: murB [H]

Synonym: APL_1851

Alternate gene names: 126209313

Gene position: 2083027-2081993 (Counterclockwise)

Preceding gene: 126209314

Following gene: 126209312

Centisome position: 91.58

GC content: 43.38

Gene sequence:

>1035_bases
ATGAAAATGAAATACAGCTTAACCCCTTTCCATACCTTTCATTTAGCGGCAAATGCAAGCAAAATCGTTGAATTCAGCAG
TGTCGAACAATTACTTAACGAATGGCAAACCGCCGTAAACAATCATCAGCCGGTACTGATTTTAGGACAAGGCTCAAATG
TGATTTTCTTAGATGATTTTGACGGTTGCGTATTCATCAATAAATTAAAAGGTATCGAACATCACGAAGATGAACAATTC
CACTATCTGCACGTGCAAGGCGGTGAAAATTGGCATGAGCTGGTGAAATGGACGCTAGCAAACAATATTGCAGGTCTTGA
GAATCTCGCACTCATTCCGGGTGTTGCAGGTTCTGCGCCGATTCAAAATATCGGTGCTTACGGGGTTGAATTTGAGCGAG
TGTGTGATTTTGTCGAAGTACTGAATTTACGCACCGGCAAAACTTTCCGTTTAACCAAGCAAGAGTGCCAATTCGGTTAT
CGTGAAAGTGTGTTTAAACACCAGTACAAAGATGAATTTGCGATTCTCTCAGTCGGAATCAAATTAGCGAAAGCATGGCA
GCCGGTATTAAGTTACGGCTCATTAACTCAATTTGATCCGCAAAGCGTAACCCCTCAACAAGTATTTGACGAAGTGTGTG
CAGTTCGTTCCGCAAAATTACCGAATCCGGACGAGTTTGGTAATGCCGGTAGTTTCTTTAAAAATCCGGTGATTAATGCT
GCAAAATTTGCGCAAATTCAGACCGCTTACCCGAATATTCCAAACTATCCGCAGGTAGACGGCACAGTAAAATTGGCAGC
GGGTTGGTTGATTGACCAATGCGAATTGAAAGGCTTTCAAGTAGGTGGCGCGGCGGTACATGAAAAACAAGCGTTGGTAC
TGATTAATAAGCAATCGGCAGCTGGTTCAGATGTAGTGGCGTTAGCGAAAGAAGTACGCCGCTGTGTACGTGAAAAATTC
GGGGTTGAGCTGCATCCGGAAGTACGTTTTATGGGCAAAAATGGCGAAGTGAATAGCGAAGAAGTCACGAGATAA

Upstream 100 bases:

>100_bases
CAAGAGGGTTATTTTTTTGTTCCATTTTAATTAGTGCTACTCTTCCTGTGTTTATATTTGTGTTTATGATAAACTCTTCA
TAACTTTTATTCACTTATAG

Downstream 100 bases:

>100_bases
CCAAAGTTATGAGCAAATTAAACCAATCTCAGATCCAAACGGCATTATTGTGCGGGCAAGCGTTGGTGTTTGATGAAATT
GATTCGACCAACGAATATTT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKMKYSLTPFHTFHLAANASKIVEFSSVEQLLNEWQTAVNNHQPVLILGQGSNVIFLDDFDGCVFINKLKGIEHHEDEQF
HYLHVQGGENWHELVKWTLANNIAGLENLALIPGVAGSAPIQNIGAYGVEFERVCDFVEVLNLRTGKTFRLTKQECQFGY
RESVFKHQYKDEFAILSVGIKLAKAWQPVLSYGSLTQFDPQSVTPQQVFDEVCAVRSAKLPNPDEFGNAGSFFKNPVINA
AKFAQIQTAYPNIPNYPQVDGTVKLAAGWLIDQCELKGFQVGGAAVHEKQALVLINKQSAAGSDVVALAKEVRRCVREKF
GVELHPEVRFMGKNGEVNSEEVTR

Sequences:

>Translated_344_residues
MKMKYSLTPFHTFHLAANASKIVEFSSVEQLLNEWQTAVNNHQPVLILGQGSNVIFLDDFDGCVFINKLKGIEHHEDEQF
HYLHVQGGENWHELVKWTLANNIAGLENLALIPGVAGSAPIQNIGAYGVEFERVCDFVEVLNLRTGKTFRLTKQECQFGY
RESVFKHQYKDEFAILSVGIKLAKAWQPVLSYGSLTQFDPQSVTPQQVFDEVCAVRSAKLPNPDEFGNAGSFFKNPVINA
AKFAQIQTAYPNIPNYPQVDGTVKLAAGWLIDQCELKGFQVGGAAVHEKQALVLINKQSAAGSDVVALAKEVRRCVREKF
GVELHPEVRFMGKNGEVNSEEVTR
>Mature_344_residues
MKMKYSLTPFHTFHLAANASKIVEFSSVEQLLNEWQTAVNNHQPVLILGQGSNVIFLDDFDGCVFINKLKGIEHHEDEQF
HYLHVQGGENWHELVKWTLANNIAGLENLALIPGVAGSAPIQNIGAYGVEFERVCDFVEVLNLRTGKTFRLTKQECQFGY
RESVFKHQYKDEFAILSVGIKLAKAWQPVLSYGSLTQFDPQSVTPQQVFDEVCAVRSAKLPNPDEFGNAGSFFKNPVINA
AKFAQIQTAYPNIPNYPQVDGTVKLAAGWLIDQCELKGFQVGGAAVHEKQALVLINKQSAAGSDVVALAKEVRRCVREKF
GVELHPEVRFMGKNGEVNSEEVTR

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=340, Percent_Identity=60.2941176470588, Blast_Score=433, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 38322; Mature: 38322

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMKYSLTPFHTFHLAANASKIVEFSSVEQLLNEWQTAVNNHQPVLILGQGSNVIFLDDF
CCEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECC
DGCVFINKLKGIEHHEDEQFHYLHVQGGENWHELVKWTLANNIAGLENLALIPGVAGSAP
CCEEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCHHEECCCCCCCCC
IQNIGAYGVEFERVCDFVEVLNLRTGKTFRLTKQECQFGYRESVFKHQYKDEFAILSVGI
HHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHCCCHHHHHHHHHHHCCCEEHHHHH
KLAKAWQPVLSYGSLTQFDPQSVTPQQVFDEVCAVRSAKLPNPDEFGNAGSFFKNPVINA
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHCCCCCH
AKFAQIQTAYPNIPNYPQVDGTVKLAAGWLIDQCELKGFQVGGAAVHEKQALVLINKQSA
HHHHEEEECCCCCCCCCCCCCEEEEEECCEEEHHCCCCEEECCCEECCCCEEEEEECCCC
AGSDVVALAKEVRRCVREKFGVELHPEVRFMGKNGEVNSEEVTR
CCCHHHHHHHHHHHHHHHHHCCEECCCEEEECCCCCCCHHHCCC
>Mature Secondary Structure
MKMKYSLTPFHTFHLAANASKIVEFSSVEQLLNEWQTAVNNHQPVLILGQGSNVIFLDDF
CCEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECC
DGCVFINKLKGIEHHEDEQFHYLHVQGGENWHELVKWTLANNIAGLENLALIPGVAGSAP
CCEEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCHHEECCCCCCCCC
IQNIGAYGVEFERVCDFVEVLNLRTGKTFRLTKQECQFGYRESVFKHQYKDEFAILSVGI
HHHCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHCCCHHHHHHHHHHHCCCEEHHHHH
KLAKAWQPVLSYGSLTQFDPQSVTPQQVFDEVCAVRSAKLPNPDEFGNAGSFFKNPVINA
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHCCCCCH
AKFAQIQTAYPNIPNYPQVDGTVKLAAGWLIDQCELKGFQVGGAAVHEKQALVLINKQSA
HHHHEEEECCCCCCCCCCCCCEEEEEECCEEEHHCCCCEEECCCEECCCCEEEEEECCCC
AGSDVVALAKEVRRCVREKFGVELHPEVRFMGKNGEVNSEEVTR
CCCHHHHHHHHHHHHHHHHHCCEECCCEEEECCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA