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The map label for this gene is torC [H]

Identifier: 126209263

GI number: 126209263

Start: 2022721

End: 2023341

Strand: Reverse

Name: torC [H]

Synonym: APL_1799

Alternate gene names: 126209263

Gene position: 2023341-2022721 (Counterclockwise)

Preceding gene: 126209270

Following gene: 126209262

Centisome position: 88.96

GC content: 43.16

Gene sequence:

>621_bases
ATGAAATCTGTTTGGCTGCTTGGCGTAAGTTTGCTGACATTCTGTTCTGCAAGTTTCGCCCAAAATTCCACCGCTTACAC
TCCCTCCGAACTAGCTCTTTTCGCTGACGAATCACTCAAGCAATCTATCGGGCAACTTGAAGCCGGTGTGCCGATTAAAC
TGCTGCAATCCAAACAAGACGCTTCACAAATCGAATTGGAAATGTGGCGTAAAGATAAAGGTTTGGGGCGTATTTGGTAT
AACCAATTTTCCAAACATATTACCGATGCGGTAATGGATAAAAACTTTATGCAAAATAACCCTACGTTTGAAGTGCTTGA
GAAGAAAGAAGATCCGCTTACCGGTTTAGTGTGGCAGAAAGTCAAATTACAAGCGTGGGTAAAAAATTCTAAATTCACTG
ATAGTCTGACCGATTTTTGGGCGAATGCGGAGCAAACCTTTAAGACCGAATGTAGCGTTTGTCACAAACAACGTGATACC
AAAATGCACGATGCGAATGAATGGGTTGCCGTATTTAACGGTATGGTCGGCTTTACCGATATGGACGAACCGACCCGTAA
ACAAGTGCTACGTTATTTGCAAATGCACGCTTCAGACAGCCAACCGAAAGCCGCTAAATAA

Upstream 100 bases:

>100_bases
TAATAAGAATAGTTATTATTTTATGACTTATATCAATATAGCTTTAACGTTATATTTGCTAAACTAGTCTAATAATTAAA
CATTATTCTCCGAGGTTTTT

Downstream 100 bases:

>100_bases
GGAGTTTGTATGTCATCATCACTTTCAACTTCACGCCGTCAATTCTTAAAAAATATGTCGCTGATGGCGGCTTCTATGGC
AATGCCGAATTTCCTTGTGC

Product: pentahemic c-type cytochrome

Products: H2O; trimethylamine; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKSVWLLGVSLLTFCSASFAQNSTAYTPSELALFADESLKQSIGQLEAGVPIKLLQSKQDASQIELEMWRKDKGLGRIWY
NQFSKHITDAVMDKNFMQNNPTFEVLEKKEDPLTGLVWQKVKLQAWVKNSKFTDSLTDFWANAEQTFKTECSVCHKQRDT
KMHDANEWVAVFNGMVGFTDMDEPTRKQVLRYLQMHASDSQPKAAK

Sequences:

>Translated_206_residues
MKSVWLLGVSLLTFCSASFAQNSTAYTPSELALFADESLKQSIGQLEAGVPIKLLQSKQDASQIELEMWRKDKGLGRIWY
NQFSKHITDAVMDKNFMQNNPTFEVLEKKEDPLTGLVWQKVKLQAWVKNSKFTDSLTDFWANAEQTFKTECSVCHKQRDT
KMHDANEWVAVFNGMVGFTDMDEPTRKQVLRYLQMHASDSQPKAAK
>Mature_206_residues
MKSVWLLGVSLLTFCSASFAQNSTAYTPSELALFADESLKQSIGQLEAGVPIKLLQSKQDASQIELEMWRKDKGLGRIWY
NQFSKHITDAVMDKNFMQNNPTFEVLEKKEDPLTGLVWQKVKLQAWVKNSKFTDSLTDFWANAEQTFKTECSVCHKQRDT
KMHDANEWVAVFNGMVGFTDMDEPTRKQVLRYLQMHASDSQPKAAK

Specific function: Part of the anaerobic respiratory chain of trimethylamine-N-oxide reductase TorA. Acts by transferring electrons from the membranous menaquinones to TorA. This transfer probably involves an electron transfer pathway from menaquinones to the N-terminal dom

COG id: COG3005

COG function: function code C; Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TorC/TorY family [H]

Homologues:

Organism=Escherichia coli, GI1787230, Length=181, Percent_Identity=30.3867403314917, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009154
- InterPro:   IPR011031
- InterPro:   IPR005126 [H]

Pfam domain/function: PF03264 Cytochrom_NNT [H]

EC number: NA

Molecular weight: Translated: 23565; Mature: 23565

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVWLLGVSLLTFCSASFAQNSTAYTPSELALFADESLKQSIGQLEAGVPIKLLQSKQD
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
ASQIELEMWRKDKGLGRIWYNQFSKHITDAVMDKNFMQNNPTFEVLEKKEDPLTGLVWQK
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHH
VKLQAWVKNSKFTDSLTDFWANAEQTFKTECSVCHKQRDTKMHDANEWVAVFNGMVGFTD
HHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCC
MDEPTRKQVLRYLQMHASDSQPKAAK
CCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKSVWLLGVSLLTFCSASFAQNSTAYTPSELALFADESLKQSIGQLEAGVPIKLLQSKQD
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
ASQIELEMWRKDKGLGRIWYNQFSKHITDAVMDKNFMQNNPTFEVLEKKEDPLTGLVWQK
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHH
VKLQAWVKNSKFTDSLTDFWANAEQTFKTECSVCHKQRDTKMHDANEWVAVFNGMVGFTD
HHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCC
MDEPTRKQVLRYLQMHASDSQPKAAK
CCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: trimethylamine-N-oxide; NADH [C]

Specific reaction: trimethylamine-N-oxide + NADH = H2O + trimethylamine + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]