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The map label for this gene is torA [H]

Identifier: 126209262

GI number: 126209262

Start: 2020228

End: 2022711

Strand: Reverse

Name: torA [H]

Synonym: APL_1798

Alternate gene names: 126209262

Gene position: 2022711-2020228 (Counterclockwise)

Preceding gene: 126209263

Following gene: 126209261

Centisome position: 88.93

GC content: 46.82

Gene sequence:

>2484_bases
ATGTCATCATCACTTTCAACTTCACGCCGTCAATTCTTAAAAAATATGTCGCTGATGGCGGCTTCTATGGCAATGCCGAA
TTTCCTTGTGCCGAGAGCAAATGCCGAGGCTTCACAAGCGGTCGAAAACGGTTGGAAAATTACCGGTGCACAATGGGGAG
CGGTGCGAGCTAAAATTGAAAACGGTCGCATTGCCGAAATTAAGCCGTTCGAACTGGATAAGCACCCGACCGAAATGATT
AACGGCATTAAAGACTTGGTATACGGCGAAGCACGTATTCGTTATCCAATGGTGCGCTTAGATTGGCTTAAAAACCGCCA
CAACAGCAATAGAACACAATGTGGTGATAACCGTTTTGTGCGTGTTAGTTGGGACGAAGCACTTGACCTTTTCTATGAAG
AACTTGAGCGTATTCAGCAAAATTACGGCCCTTGGGCATTACATACCGCCAATGTCGGCTGGCGTTCTTCCGGTCAATTC
CATAGCTGCGGTAACCATATGATCCGTGCGATTGCGATGCACGGCTCGAGCGTTGGCACGGTCGGCGATTACTCCACCGG
TGCGGGGCAAACCATTTTGCCTTATGTGTTAGGTTCAACCGAAGTGTATTCACAAGGGACATCATGGGAAGTCATTCTTA
AAGAAACCGAGAATTTAATTTTCTGGGCAAGCGATCCGGTCAAAAACTTACAAGTCGGCTGGAACTGCGAAACGCACGAA
TCTTACGGTTACTTAGAACAGCTTAAACAGAAAGTGGCGGAACAAAAAATCAATGTGATTAGCATTGATCCGGTGAAAAG
CAAAACGCAAAACTTCCTTGGTTGTAAACAGCTTTATATCAATCCGCAAGCGGACGTGCCGTTTATGTTGGCGATTGCTC
ACACCTTGTATCGTGAAAATTTATACGATAAAGCGTTTATTGATATGTACACGCTCGGTTTTGAGCAATTTGTGCCTTAC
TTACTCGGCGAAACCGAAGACAAAATTGAGAAAACTGCCGAATGGGCGGCACCGATTTGCGGTATTGAAGCGGAAGAAAT
CCGCAAATTTGCCCGTATGTTAGCCGGCAAACGTACCCAGCTGATTTTCGGTTGGGCGATTCAACGCCAACAACACGGTG
AACAGCCTTACTGGATGGGCGCGGTTTTAGCCGCTATGCTCGGACAAATCGGGCTTGCCGGCGGTGGTATCAGTTATGCA
CACCATTACAGTTCTATCGGCGTATCCAGTTCCGGTGCGGCAATGCCGGGGGCATTCCCATCTACTCTGGATAAGGATCA
AGTCGCTAAATATACCAATAAAGATTACCAAGGCTATAGTGAGGTGATTCCGGTCGCTCGTACTACCGATTCTTTACTTC
ACTCCGGCGAAACCATTGACTACAACGGCAGAAAAATTACCTATGCACCGTATAAAATGGCGATTTTCTCCGGTTGTAAC
CAATGGAGCCGCCAATCCGATTTGAATAAGATGAAACGCGCCTTCCAAAAATTGGAAACCGTGGTATCGATTAACTATAG
CTGGACGGCAACTTGTCGTTTCTCCGATATTGTTTTACCGGCTTGTACGCCGTTTGAACGTAACGATATTGATGCCTACG
GTTCTTACAGCAACCGAGGCGTTTTGGCGATGCAAAAATTGATTGAGCCGTTATATGAATCTCGCCCTGATTTTGAAATT
TTCAAAGACTTATGTCGCCGATTCGGCAAAGAAAAAGAATATTGCCGAGGCATAGACGAAATGGCGTGGTTAGAACGGTT
ATACAAAGATTGTCGCAATGAAAACCGTGGTAAGTTTGAGATGCCACCTTTCGCTGAATTTTGGCAAAAAGGCTATGTGC
TATTCCCAGAAGGCAAACCTTGGGTTCGTCATGCTGATTTCCGTGAAGATCCGGAATTACACGCACTCGGCACACCTTCC
GGCTTTATCGAAATCTTTAGCCGTAAAATAGCGAGTTTCGGTTATGCTGACTGTAAAGGCCACCCGATGTGGTTTGAAAA
AGCGGAACGTTCGCACGGTGGGCCGAAATCGGATAAATACCCGTTCTGGCTACAATCCGTGCATCCGGATAAACGCTTAC
ATTCACAACTGTGTGAAGCCAAATCGTTACGTGAAACCTACAGCGTGCAAGGACGAGAACCGTTTTATATGAATCCGCAA
GATGCAGCAAAATTAGGCATTAAAGACGGCGATTTAGTACGTGTCTATAACGAACGTGGGCAAGTGTTAGTGGGTGCGGT
GTTATCCGATAACTTCCCAAGCGGTGTCGTACGTTTACAAGAAGGAGCGTGGTTCTCACCGCTTGATGAAAGCGTGGGAG
CGATTGATACTTACGGCTGCCCGAATACGCTAACACTCGATATCGGCGCTTCAAGCTTATCGCAAGCGACTTGTGTCAGT
ACCTGTTTAGTGAATGTGGAAAAATGGCAAGGCGATGCACCGGCAGCGAATGGTTTCAGCGGCCCGACAGAGGTAGCTCG
TTAA

Upstream 100 bases:

>100_bases
CTTTACCGATATGGACGAACCGACCCGTAAACAAGTGCTACGTTATTTGCAAATGCACGCTTCAGACAGCCAACCGAAAG
CCGCTAAATAAGGAGTTTGT

Downstream 100 bases:

>100_bases
TGGCACACTCGCAATTACTCAGTTCGGAAGAACGACTATTCTGTTACCGCTGGTTCCATTCGTTACTCGCCAAAGAGCTA
TCGGAACCGCAGCTACAGGC

Product: trimethylamine-N-oxide reductase precursor

Products: NA

Alternate protein names: TMAO reductase; Trimethylamine oxidase [H]

Number of amino acids: Translated: 827; Mature: 826

Protein sequence:

>827_residues
MSSSLSTSRRQFLKNMSLMAASMAMPNFLVPRANAEASQAVENGWKITGAQWGAVRAKIENGRIAEIKPFELDKHPTEMI
NGIKDLVYGEARIRYPMVRLDWLKNRHNSNRTQCGDNRFVRVSWDEALDLFYEELERIQQNYGPWALHTANVGWRSSGQF
HSCGNHMIRAIAMHGSSVGTVGDYSTGAGQTILPYVLGSTEVYSQGTSWEVILKETENLIFWASDPVKNLQVGWNCETHE
SYGYLEQLKQKVAEQKINVISIDPVKSKTQNFLGCKQLYINPQADVPFMLAIAHTLYRENLYDKAFIDMYTLGFEQFVPY
LLGETEDKIEKTAEWAAPICGIEAEEIRKFARMLAGKRTQLIFGWAIQRQQHGEQPYWMGAVLAAMLGQIGLAGGGISYA
HHYSSIGVSSSGAAMPGAFPSTLDKDQVAKYTNKDYQGYSEVIPVARTTDSLLHSGETIDYNGRKITYAPYKMAIFSGCN
QWSRQSDLNKMKRAFQKLETVVSINYSWTATCRFSDIVLPACTPFERNDIDAYGSYSNRGVLAMQKLIEPLYESRPDFEI
FKDLCRRFGKEKEYCRGIDEMAWLERLYKDCRNENRGKFEMPPFAEFWQKGYVLFPEGKPWVRHADFREDPELHALGTPS
GFIEIFSRKIASFGYADCKGHPMWFEKAERSHGGPKSDKYPFWLQSVHPDKRLHSQLCEAKSLRETYSVQGREPFYMNPQ
DAAKLGIKDGDLVRVYNERGQVLVGAVLSDNFPSGVVRLQEGAWFSPLDESVGAIDTYGCPNTLTLDIGASSLSQATCVS
TCLVNVEKWQGDAPAANGFSGPTEVAR

Sequences:

>Translated_827_residues
MSSSLSTSRRQFLKNMSLMAASMAMPNFLVPRANAEASQAVENGWKITGAQWGAVRAKIENGRIAEIKPFELDKHPTEMI
NGIKDLVYGEARIRYPMVRLDWLKNRHNSNRTQCGDNRFVRVSWDEALDLFYEELERIQQNYGPWALHTANVGWRSSGQF
HSCGNHMIRAIAMHGSSVGTVGDYSTGAGQTILPYVLGSTEVYSQGTSWEVILKETENLIFWASDPVKNLQVGWNCETHE
SYGYLEQLKQKVAEQKINVISIDPVKSKTQNFLGCKQLYINPQADVPFMLAIAHTLYRENLYDKAFIDMYTLGFEQFVPY
LLGETEDKIEKTAEWAAPICGIEAEEIRKFARMLAGKRTQLIFGWAIQRQQHGEQPYWMGAVLAAMLGQIGLAGGGISYA
HHYSSIGVSSSGAAMPGAFPSTLDKDQVAKYTNKDYQGYSEVIPVARTTDSLLHSGETIDYNGRKITYAPYKMAIFSGCN
QWSRQSDLNKMKRAFQKLETVVSINYSWTATCRFSDIVLPACTPFERNDIDAYGSYSNRGVLAMQKLIEPLYESRPDFEI
FKDLCRRFGKEKEYCRGIDEMAWLERLYKDCRNENRGKFEMPPFAEFWQKGYVLFPEGKPWVRHADFREDPELHALGTPS
GFIEIFSRKIASFGYADCKGHPMWFEKAERSHGGPKSDKYPFWLQSVHPDKRLHSQLCEAKSLRETYSVQGREPFYMNPQ
DAAKLGIKDGDLVRVYNERGQVLVGAVLSDNFPSGVVRLQEGAWFSPLDESVGAIDTYGCPNTLTLDIGASSLSQATCVS
TCLVNVEKWQGDAPAANGFSGPTEVAR
>Mature_826_residues
SSSLSTSRRQFLKNMSLMAASMAMPNFLVPRANAEASQAVENGWKITGAQWGAVRAKIENGRIAEIKPFELDKHPTEMIN
GIKDLVYGEARIRYPMVRLDWLKNRHNSNRTQCGDNRFVRVSWDEALDLFYEELERIQQNYGPWALHTANVGWRSSGQFH
SCGNHMIRAIAMHGSSVGTVGDYSTGAGQTILPYVLGSTEVYSQGTSWEVILKETENLIFWASDPVKNLQVGWNCETHES
YGYLEQLKQKVAEQKINVISIDPVKSKTQNFLGCKQLYINPQADVPFMLAIAHTLYRENLYDKAFIDMYTLGFEQFVPYL
LGETEDKIEKTAEWAAPICGIEAEEIRKFARMLAGKRTQLIFGWAIQRQQHGEQPYWMGAVLAAMLGQIGLAGGGISYAH
HYSSIGVSSSGAAMPGAFPSTLDKDQVAKYTNKDYQGYSEVIPVARTTDSLLHSGETIDYNGRKITYAPYKMAIFSGCNQ
WSRQSDLNKMKRAFQKLETVVSINYSWTATCRFSDIVLPACTPFERNDIDAYGSYSNRGVLAMQKLIEPLYESRPDFEIF
KDLCRRFGKEKEYCRGIDEMAWLERLYKDCRNENRGKFEMPPFAEFWQKGYVLFPEGKPWVRHADFREDPELHALGTPSG
FIEIFSRKIASFGYADCKGHPMWFEKAERSHGGPKSDKYPFWLQSVHPDKRLHSQLCEAKSLRETYSVQGREPFYMNPQD
AAKLGIKDGDLVRVYNERGQVLVGAVLSDNFPSGVVRLQEGAWFSPLDESVGAIDTYGCPNTLTLDIGASSLSQATCVST
CLVNVEKWQGDAPAANGFSGPTEVAR

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787231, Length=833, Percent_Identity=52.3409363745498, Blast_Score=895, Evalue=0.0,
Organism=Escherichia coli, GI87081994, Length=828, Percent_Identity=38.2850241545894, Blast_Score=570, Evalue=1e-164,
Organism=Escherichia coli, GI145693196, Length=791, Percent_Identity=38.685208596713, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI87081797, Length=858, Percent_Identity=26.4568764568765, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1787870, Length=857, Percent_Identity=25.5542590431739, Blast_Score=233, Evalue=4e-62,
Organism=Escherichia coli, GI171474008, Length=748, Percent_Identity=27.5401069518717, Blast_Score=230, Evalue=4e-61,
Organism=Escherichia coli, GI3868721, Length=708, Percent_Identity=22.8813559322034, Blast_Score=133, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311
- InterPro:   IPR011887 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 93265; Mature: 93133

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2 ; PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSLSTSRRQFLKNMSLMAASMAMPNFLVPRANAEASQAVENGWKITGAQWGAVRAKIE
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCEEECCCCCEEEEEEC
NGRIAEIKPFELDKHPTEMINGIKDLVYGEARIRYPMVRLDWLKNRHNSNRTQCGDNRFV
CCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHCCCCCCCCCCCCCCEE
RVSWDEALDLFYEELERIQQNYGPWALHTANVGWRSSGQFHSCGNHMIRAIAMHGSSVGT
EEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
VGDYSTGAGQTILPYVLGSTEVYSQGTSWEVILKETENLIFWASDPVKNLQVGWNCETHE
CCCCCCCCCCEEHHHHCCCCHHHCCCCCEEEEEEECCCEEEEECCCCCCCEECCCCCCCC
SYGYLEQLKQKVAEQKINVISIDPVKSKTQNFLGCKQLYINPQADVPFMLAIAHTLYREN
HHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCHHEEECCCCCCCHHHHHHHHHHHHC
LYDKAFIDMYTLGFEQFVPYLLGETEDKIEKTAEWAAPICGIEAEEIRKFARMLAGKRTQ
CCHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCE
LIFGWAIQRQQHGEQPYWMGAVLAAMLGQIGLAGGGISYAHHYSSIGVSSSGAAMPGAFP
EEEHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
STLDKDQVAKYTNKDYQGYSEVIPVARTTDSLLHSGETIDYNGRKITYAPYKMAIFSGCN
CCCCHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHCCCEEECCCCEEEECCHHHHHHHCCC
QWSRQSDLNKMKRAFQKLETVVSINYSWTATCRFSDIVLPACTPFERNDIDAYGSYSNRG
HHHHHHHHHHHHHHHHHHHHHEEECCEEEEEEEECCEEECCCCCCCCCCCCCCCCCCCCC
VLAMQKLIEPLYESRPDFEIFKDLCRRFGKEKEYCRGIDEMAWLERLYKDCRNENRGKFE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
MPPFAEFWQKGYVLFPEGKPWVRHADFREDPELHALGTPSGFIEIFSRKIASFGYADCKG
CCCHHHHHHCCEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCC
HPMWFEKAERSHGGPKSDKYPFWLQSVHPDKRLHSQLCEAKSLRETYSVQGREPFYMNPQ
CCHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCH
DAAKLGIKDGDLVRVYNERGQVLVGAVLSDNFPSGVVRLQEGAWFSPLDESVGAIDTYGC
HHHHCCCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEECCCCCCCCHHHHCCCEECCCC
PNTLTLDIGASSLSQATCVSTCLVNVEKWQGDAPAANGFSGPTEVAR
CCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCC
>Mature Secondary Structure 
SSSLSTSRRQFLKNMSLMAASMAMPNFLVPRANAEASQAVENGWKITGAQWGAVRAKIE
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCEEECCCCCEEEEEEC
NGRIAEIKPFELDKHPTEMINGIKDLVYGEARIRYPMVRLDWLKNRHNSNRTQCGDNRFV
CCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHCCCCCCCCCCCCCCEE
RVSWDEALDLFYEELERIQQNYGPWALHTANVGWRSSGQFHSCGNHMIRAIAMHGSSVGT
EEEHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
VGDYSTGAGQTILPYVLGSTEVYSQGTSWEVILKETENLIFWASDPVKNLQVGWNCETHE
CCCCCCCCCCEEHHHHCCCCHHHCCCCCEEEEEEECCCEEEEECCCCCCCEECCCCCCCC
SYGYLEQLKQKVAEQKINVISIDPVKSKTQNFLGCKQLYINPQADVPFMLAIAHTLYREN
HHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCHHEEECCCCCCCHHHHHHHHHHHHC
LYDKAFIDMYTLGFEQFVPYLLGETEDKIEKTAEWAAPICGIEAEEIRKFARMLAGKRTQ
CCHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCE
LIFGWAIQRQQHGEQPYWMGAVLAAMLGQIGLAGGGISYAHHYSSIGVSSSGAAMPGAFP
EEEHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
STLDKDQVAKYTNKDYQGYSEVIPVARTTDSLLHSGETIDYNGRKITYAPYKMAIFSGCN
CCCCHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHCCCEEECCCCEEEECCHHHHHHHCCC
QWSRQSDLNKMKRAFQKLETVVSINYSWTATCRFSDIVLPACTPFERNDIDAYGSYSNRG
HHHHHHHHHHHHHHHHHHHHHEEECCEEEEEEEECCEEECCCCCCCCCCCCCCCCCCCCC
VLAMQKLIEPLYESRPDFEIFKDLCRRFGKEKEYCRGIDEMAWLERLYKDCRNENRGKFE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCC
MPPFAEFWQKGYVLFPEGKPWVRHADFREDPELHALGTPSGFIEIFSRKIASFGYADCKG
CCCHHHHHHCCEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCC
HPMWFEKAERSHGGPKSDKYPFWLQSVHPDKRLHSQLCEAKSLRETYSVQGREPFYMNPQ
CCHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCH
DAAKLGIKDGDLVRVYNERGQVLVGAVLSDNFPSGVVRLQEGAWFSPLDESVGAIDTYGC
HHHHCCCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEECCCCCCCCHHHHCCCEECCCC
PNTLTLDIGASSLSQATCVSTCLVNVEKWQGDAPAANGFSGPTEVAR
CCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]