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The map label for this gene is secY [H]

Identifier: 126209243

GI number: 126209243

Start: 2006037

End: 2007359

Strand: Direct

Name: secY [H]

Synonym: APL_1779

Alternate gene names: 126209243

Gene position: 2006037-2007359 (Clockwise)

Preceding gene: 126209242

Following gene: 126209244

Centisome position: 88.2

GC content: 38.32

Gene sequence:

>1323_bases
ATGGCAAAGCAACCAGGGTACCAAGGTAGTACACAAAAAGGGACTGGCGAGCTTAAATCAAGATTATTATTTGTTTTAGG
TGCGTTAATCGTTTTCCGTATCGGTTCTTTTATACCTGTTCCTGGCATTGATGCTTCTGTATTATCCGAATTAGTTCGAC
AACAGCAAGGCACCATCATTGACATGTTCAATATGTTCTCTGGTGGTGCTTTAAGCCGAGCGTCTATATTTGCATTAGGT
ATTATGCCTTATATTTCGGCGTCAATTATTGTTCAATTATTGACAGCGATTCATCCTCCTTTAGCAGAGCTGAAGAAAGA
AGGTGAGGCAGGACGTCGTAAGATTAGTAAATATACTCGTTATGGTACATTGTTATTAGCATTTATTCAGTCTATTGGTA
TTTCAATTGCCCTACCGAATATGTTACAAGGATTAGTTCCTAATCCAAGTATCTTATTCTATGTAACTTCTGTAATCAGC
CTAGTTACGGGAACAATGTTCCTTATGTGGTTAGGTGAGCAAATCACTGAGCGCGGTATCGGTAACGGTATCTCTTTGAT
TATCTTTGCAGGTATTGTTGCAGATTTACCAGCAACGATTGGGCAGACAATTGAGCAAGCTCGTCAAGGCGAAATTTCTC
CACTTGTTCTTTTATTAGTAGCTATAATTGCATTTGCAGTAACATATTTTGTTGTCTTTGTTGAACGCGGACAAAGAAGA
ATTGTGGTAAATTATGCAAGTCGCCAGCAAGGCAGAATGATGGCACCGGCTAGATCATCTCATTTACCATTAAAAGTTAA
TATGGCAGGTGTAATTCCTGCGATTTTCGCTTCAAGTATCATTTTATTCCCTGCGAGTGTTACGCAGTGGTTTGGTCAAA
GCGAAGGACTTGAGTGGTTATTTGACTTATCACAATTATTACAGCCAGGACAACCGTTATATCTTGTGTTATTCACAATG
GCAGTAATCTTCTTTGCATTTTTCTATACGGGAATGCAATATAATCCTCGTGATACGGCGGATAATTTGAAGAAATCAGG
TGCGTTTGTACCAGGTTATCGACCAGGCGAACAAACATCACGTTATATTGATAAAGTAATGACGCGTTTAACCTTAATCG
GTGCGTTATATATTACTTTTGTTTGTTTGGTTCCTTATATCATTACATCTCTATGGAAAGTACCATTCCAATTAGGCGGT
ACTTCACTATTAATCGTAGTGGTAGTTATTATGGATTTCATCGCACAGGTTCAAAGTCATTTAATGTCATTACAATATGA
CTCTGTGTTGAAGAAAGCCAATTTGAAAGGCTTAGGGCAATAG

Upstream 100 bases:

>100_bases
GGGTAAAATTGAAAAAGCGGTTGTAGTTAAAGGTTTAGGTGTGACTAAAGGCGCTAAAGCTGCTATCGAAGCTGCTGGCG
GTTCTATCGAGGAATAATAG

Downstream 100 bases:

>100_bases
TCCCTTAGATCAAAAAGGATAAGCAATGAAAGTTCGTGCTTCAGTTAAGAAATTATGCCGTAACTGTAAAGTTGTTAAAC
GTCAAGGTGTTGTTCGCGTA

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MAKQPGYQGSTQKGTGELKSRLLFVLGALIVFRIGSFIPVPGIDASVLSELVRQQQGTIIDMFNMFSGGALSRASIFALG
IMPYISASIIVQLLTAIHPPLAELKKEGEAGRRKISKYTRYGTLLLAFIQSIGISIALPNMLQGLVPNPSILFYVTSVIS
LVTGTMFLMWLGEQITERGIGNGISLIIFAGIVADLPATIGQTIEQARQGEISPLVLLLVAIIAFAVTYFVVFVERGQRR
IVVNYASRQQGRMMAPARSSHLPLKVNMAGVIPAIFASSIILFPASVTQWFGQSEGLEWLFDLSQLLQPGQPLYLVLFTM
AVIFFAFFYTGMQYNPRDTADNLKKSGAFVPGYRPGEQTSRYIDKVMTRLTLIGALYITFVCLVPYIITSLWKVPFQLGG
TSLLIVVVVIMDFIAQVQSHLMSLQYDSVLKKANLKGLGQ

Sequences:

>Translated_440_residues
MAKQPGYQGSTQKGTGELKSRLLFVLGALIVFRIGSFIPVPGIDASVLSELVRQQQGTIIDMFNMFSGGALSRASIFALG
IMPYISASIIVQLLTAIHPPLAELKKEGEAGRRKISKYTRYGTLLLAFIQSIGISIALPNMLQGLVPNPSILFYVTSVIS
LVTGTMFLMWLGEQITERGIGNGISLIIFAGIVADLPATIGQTIEQARQGEISPLVLLLVAIIAFAVTYFVVFVERGQRR
IVVNYASRQQGRMMAPARSSHLPLKVNMAGVIPAIFASSIILFPASVTQWFGQSEGLEWLFDLSQLLQPGQPLYLVLFTM
AVIFFAFFYTGMQYNPRDTADNLKKSGAFVPGYRPGEQTSRYIDKVMTRLTLIGALYITFVCLVPYIITSLWKVPFQLGG
TSLLIVVVVIMDFIAQVQSHLMSLQYDSVLKKANLKGLGQ
>Mature_439_residues
AKQPGYQGSTQKGTGELKSRLLFVLGALIVFRIGSFIPVPGIDASVLSELVRQQQGTIIDMFNMFSGGALSRASIFALGI
MPYISASIIVQLLTAIHPPLAELKKEGEAGRRKISKYTRYGTLLLAFIQSIGISIALPNMLQGLVPNPSILFYVTSVISL
VTGTMFLMWLGEQITERGIGNGISLIIFAGIVADLPATIGQTIEQARQGEISPLVLLLVAIIAFAVTYFVVFVERGQRRI
VVNYASRQQGRMMAPARSSHLPLKVNMAGVIPAIFASSIILFPASVTQWFGQSEGLEWLFDLSQLLQPGQPLYLVLFTMA
VIFFAFFYTGMQYNPRDTADNLKKSGAFVPGYRPGEQTSRYIDKVMTRLTLIGALYITFVCLVPYIITSLWKVPFQLGGT
SLLIVVVVIMDFIAQVQSHLMSLQYDSVLKKANLKGLGQ

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=443, Percent_Identity=74.7178329571106, Blast_Score=609, Evalue=1e-175,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48205; Mature: 48074

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQPGYQGSTQKGTGELKSRLLFVLGALIVFRIGSFIPVPGIDASVLSELVRQQQGTII
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCH
DMFNMFSGGALSRASIFALGIMPYISASIIVQLLTAIHPPLAELKKEGEAGRRKISKYTR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHH
YGTLLLAFIQSIGISIALPNMLQGLVPNPSILFYVTSVISLVTGTMFLMWLGEQITERGI
HHHHHHHHHHHHCCCEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GNGISLIIFAGIVADLPATIGQTIEQARQGEISPLVLLLVAIIAFAVTYFVVFVERGQRR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
IVVNYASRQQGRMMAPARSSHLPLKVNMAGVIPAIFASSIILFPASVTQWFGQSEGLEWL
EEEEECCCCCCCEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
FDLSQLLQPGQPLYLVLFTMAVIFFAFFYTGMQYNPRDTADNLKKSGAFVPGYRPGEQTS
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCHHHH
RYIDKVMTRLTLIGALYITFVCLVPYIITSLWKVPFQLGGTSLLIVVVVIMDFIAQVQSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LMSLQYDSVLKKANLKGLGQ
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AKQPGYQGSTQKGTGELKSRLLFVLGALIVFRIGSFIPVPGIDASVLSELVRQQQGTII
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCH
DMFNMFSGGALSRASIFALGIMPYISASIIVQLLTAIHPPLAELKKEGEAGRRKISKYTR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHH
YGTLLLAFIQSIGISIALPNMLQGLVPNPSILFYVTSVISLVTGTMFLMWLGEQITERGI
HHHHHHHHHHHHCCCEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GNGISLIIFAGIVADLPATIGQTIEQARQGEISPLVLLLVAIIAFAVTYFVVFVERGQRR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
IVVNYASRQQGRMMAPARSSHLPLKVNMAGVIPAIFASSIILFPASVTQWFGQSEGLEWL
EEEEECCCCCCCEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
FDLSQLLQPGQPLYLVLFTMAVIFFAFFYTGMQYNPRDTADNLKKSGAFVPGYRPGEQTS
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCHHHH
RYIDKVMTRLTLIGALYITFVCLVPYIITSLWKVPFQLGGTSLLIVVVVIMDFIAQVQSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LMSLQYDSVLKKANLKGLGQ
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]