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The map label for this gene is comM [H]

Identifier: 126209211

GI number: 126209211

Start: 1983337

End: 1984863

Strand: Direct

Name: comM [H]

Synonym: APL_1747

Alternate gene names: 126209211

Gene position: 1983337-1984863 (Clockwise)

Preceding gene: 126209206

Following gene: 126209212

Centisome position: 87.2

GC content: 46.82

Gene sequence:

>1527_bases
ATGTCTTTAGCCATTGTTTATAGCCGTGCATCGATCGGTGTAGAAGCGCCGTTGGTAACGATTGAAGTGCATTTAAGTAA
CGGAAAACCGGGGCTAACGATTGTTGGCTTACCGGAAACCACGGTAAAAGAGGCGGGCGATCGGGTGCGTAGTGCATTGA
TGAATGCGAATTTTATGTATCCTCCGCAACGGATCACGATTAACCTCGCACCGGCGGATCTACCTAAAGAGGGCGGGCGT
TTTGATCTGCCGATTGCGATCGGGATCTTAGCTGCCTCAGGGCAGATGGATTCGGATCGCTTAAAACAGTTTGAGTTTTT
GGGGGAACTGGCTTTAACGGGATCGTTACGAGGCGTTCACGGCGTGATTCCGGCGGTAATTTCCGCCGAAAAAGCCAAGC
GGCAGATGATTATTGCCCGCCCGAATGTGAATGAAGCGTCGTTAGTGTCGAATGCCGAAACTTATTTTGCCGGTTCATTA
TTGCAGGTGGTGAATTTTATGAATAAGCGGGACAGTCTGCCGATTGCTCAGCAGATTCCGCAAAAAACACAAGAAATTCA
ACCGCTTGTAAAACGTGATTTAACCGATATTATCGGGCAACAGCATGCTAAACGAGCGTTGATGATTGCGGCTGCCGGAC
AACATAATTTACTTTTCCTTGGTCCTCCCGGTACCGGCAAAACGATGCTCGCCAGTCGTCTAGCGGATTTGTTACCGGCA
ATGAGTGATGACGAAGCGATTGAAACCGCTTCGGTCACTAGCTTAGTACAAAATGAATTGAATTTTCATAACTGGAAAGA
ACGTCCGTTTCGAGCACCGCATCACAGTGCATCTATGGTGGCGTTGGTGGGTGGCGGTTCTATTCCTAAACCGGGTGAAA
TCAGTTTGGCACACAATGGTGTTCTTTTTTTAGACGAATTGCCTGAGTTTGAACGCAAAGTGCTGGACGCATTACGCCAG
CCGTTGGAAGCCGGTGAGATTATTATTTCCAGAGCGAATGCTAAGGTGCAGTTCCCCGCCAGTTTTCAATTAATTGCGGC
AATGAACCCTAGCCCGACAGGGCATTATCAAGGCACGCACAATCGTACTTCTCCGCAACAAGTGATACGTTATTTAAATC
GTTTATCCGGCCCGTTTTTAGACCGTTTTGACTTATCAATTGAAGTCCCTTTATTACCGAAAGGCGCATTACAAAGTAGC
GATAACCGAGGTGAAACCACCGAGCAAGTACGCAAGCGGGTACTTTCGGCAAGAGAATTACAAATGGCGAGAGCCGGTAA
AATTAATGCTAAATTAACCACCAAAGAAATCGAACGTGATTGTCGCCTTGCAGAAAAAGACGCGCTATTTCTAGAAAATG
CACTGACAAAATTAGGACTTTCAGTGCGTGCCTATCATAGGATTTTAAAAGTTTCCCGCACAATTGCCGATTTGGCGAAC
GAACCGAATATTCAACAAATCCATCTTGCCGAAGCGTTAGGTTATCGAGCGATGGATCGGCTTTTGCAGAGGTTGCAGAA
CGATTAA

Upstream 100 bases:

>100_bases
AAAGAAACTTACTTTTGCGATCCTGATCGAGAAAAGTGATTTTGTTGCTGTGACATAGAACATTTATCTTTTACCCTCCT
AACAATTTTTAGGAGGAAAG

Downstream 100 bases:

>100_bases
ATTGTAAACTTTAGAGCTTTATATTTTGTTTGATGGTATTATATTTACTTATATTTATGATTTTTAGTTTTTATTGTAAA
TTAAAGTGTTTATTTATTGT

Product: competence protein comM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MSLAIVYSRASIGVEAPLVTIEVHLSNGKPGLTIVGLPETTVKEAGDRVRSALMNANFMYPPQRITINLAPADLPKEGGR
FDLPIAIGILAASGQMDSDRLKQFEFLGELALTGSLRGVHGVIPAVISAEKAKRQMIIARPNVNEASLVSNAETYFAGSL
LQVVNFMNKRDSLPIAQQIPQKTQEIQPLVKRDLTDIIGQQHAKRALMIAAAGQHNLLFLGPPGTGKTMLASRLADLLPA
MSDDEAIETASVTSLVQNELNFHNWKERPFRAPHHSASMVALVGGGSIPKPGEISLAHNGVLFLDELPEFERKVLDALRQ
PLEAGEIIISRANAKVQFPASFQLIAAMNPSPTGHYQGTHNRTSPQQVIRYLNRLSGPFLDRFDLSIEVPLLPKGALQSS
DNRGETTEQVRKRVLSARELQMARAGKINAKLTTKEIERDCRLAEKDALFLENALTKLGLSVRAYHRILKVSRTIADLAN
EPNIQQIHLAEALGYRAMDRLLQRLQND

Sequences:

>Translated_508_residues
MSLAIVYSRASIGVEAPLVTIEVHLSNGKPGLTIVGLPETTVKEAGDRVRSALMNANFMYPPQRITINLAPADLPKEGGR
FDLPIAIGILAASGQMDSDRLKQFEFLGELALTGSLRGVHGVIPAVISAEKAKRQMIIARPNVNEASLVSNAETYFAGSL
LQVVNFMNKRDSLPIAQQIPQKTQEIQPLVKRDLTDIIGQQHAKRALMIAAAGQHNLLFLGPPGTGKTMLASRLADLLPA
MSDDEAIETASVTSLVQNELNFHNWKERPFRAPHHSASMVALVGGGSIPKPGEISLAHNGVLFLDELPEFERKVLDALRQ
PLEAGEIIISRANAKVQFPASFQLIAAMNPSPTGHYQGTHNRTSPQQVIRYLNRLSGPFLDRFDLSIEVPLLPKGALQSS
DNRGETTEQVRKRVLSARELQMARAGKINAKLTTKEIERDCRLAEKDALFLENALTKLGLSVRAYHRILKVSRTIADLAN
EPNIQQIHLAEALGYRAMDRLLQRLQND
>Mature_507_residues
SLAIVYSRASIGVEAPLVTIEVHLSNGKPGLTIVGLPETTVKEAGDRVRSALMNANFMYPPQRITINLAPADLPKEGGRF
DLPIAIGILAASGQMDSDRLKQFEFLGELALTGSLRGVHGVIPAVISAEKAKRQMIIARPNVNEASLVSNAETYFAGSLL
QVVNFMNKRDSLPIAQQIPQKTQEIQPLVKRDLTDIIGQQHAKRALMIAAAGQHNLLFLGPPGTGKTMLASRLADLLPAM
SDDEAIETASVTSLVQNELNFHNWKERPFRAPHHSASMVALVGGGSIPKPGEISLAHNGVLFLDELPEFERKVLDALRQP
LEAGEIIISRANAKVQFPASFQLIAAMNPSPTGHYQGTHNRTSPQQVIRYLNRLSGPFLDRFDLSIEVPLLPKGALQSSD
NRGETTEQVRKRVLSARELQMARAGKINAKLTTKEIERDCRLAEKDALFLENALTKLGLSVRAYHRILKVSRTIADLANE
PNIQQIHLAEALGYRAMDRLLQRLQND

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=507, Percent_Identity=57.396449704142, Blast_Score=606, Evalue=1e-175,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 55657; Mature: 55526

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAIVYSRASIGVEAPLVTIEVHLSNGKPGLTIVGLPETTVKEAGDRVRSALMNANFMY
CCEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCC
PPQRITINLAPADLPKEGGRFDLPIAIGILAASGQMDSDRLKQFEFLGELALTGSLRGVH
CCCEEEEEECCCCCCCCCCCEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHH
GVIPAVISAEKAKRQMIIARPNVNEASLVSNAETYFAGSLLQVVNFMNKRDSLPIAQQIP
HHHHHHHHHHHHHCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
QKTQEIQPLVKRDLTDIIGQQHAKRALMIAAAGQHNLLFLGPPGTGKTMLASRLADLLPA
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHCC
MSDDEAIETASVTSLVQNELNFHNWKERPFRAPHHSASMVALVGGGSIPKPGEISLAHNG
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEECCC
VLFLDELPEFERKVLDALRQPLEAGEIIISRANAKVQFPASFQLIAAMNPSPTGHYQGTH
EEEECCCCHHHHHHHHHHHCCHHHCCEEEEECCCEEECCCCEEEEEECCCCCCCCCCCCC
NRTSPQQVIRYLNRLSGPFLDRFDLSIEVPLLPKGALQSSDNRGETTEQVRKRVLSAREL
CCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QMARAGKINAKLTTKEIERDCRLAEKDALFLENALTKLGLSVRAYHRILKVSRTIADLAN
HHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
EPNIQQIHLAEALGYRAMDRLLQRLQND
CCCCCEEHHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLAIVYSRASIGVEAPLVTIEVHLSNGKPGLTIVGLPETTVKEAGDRVRSALMNANFMY
CEEEEEECCCCCCCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCC
PPQRITINLAPADLPKEGGRFDLPIAIGILAASGQMDSDRLKQFEFLGELALTGSLRGVH
CCCEEEEEECCCCCCCCCCCEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHH
GVIPAVISAEKAKRQMIIARPNVNEASLVSNAETYFAGSLLQVVNFMNKRDSLPIAQQIP
HHHHHHHHHHHHHCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
QKTQEIQPLVKRDLTDIIGQQHAKRALMIAAAGQHNLLFLGPPGTGKTMLASRLADLLPA
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHCC
MSDDEAIETASVTSLVQNELNFHNWKERPFRAPHHSASMVALVGGGSIPKPGEISLAHNG
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEECCC
VLFLDELPEFERKVLDALRQPLEAGEIIISRANAKVQFPASFQLIAAMNPSPTGHYQGTH
EEEECCCCHHHHHHHHHHHCCHHHCCEEEEECCCEEECCCCEEEEEECCCCCCCCCCCCC
NRTSPQQVIRYLNRLSGPFLDRFDLSIEVPLLPKGALQSSDNRGETTEQVRKRVLSAREL
CCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QMARAGKINAKLTTKEIERDCRLAEKDALFLENALTKLGLSVRAYHRILKVSRTIADLAN
HHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
EPNIQQIHLAEALGYRAMDRLLQRLQND
CCCCCEEHHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]