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The map label for this gene is gntK [H]

Identifier: 126209130

GI number: 126209130

Start: 1892235

End: 1892750

Strand: Direct

Name: gntK [H]

Synonym: APL_1666

Alternate gene names: 126209130

Gene position: 1892235-1892750 (Clockwise)

Preceding gene: 126209120

Following gene: 126209132

Centisome position: 83.19

GC content: 39.15

Gene sequence:

>516_bases
ATGAAATCTGGTCAAAGTTTTATTTTAATGGGTGTATCAAGCACCGGTAAAACCACAATAGGCAGTGAAGTGGCTCGTCG
TTTAGGCATTAAATTGATCGACGGCGATGATCTGCATCCGAGAGCGAATATCCTCAAAATGAGTCAAGGACAACCGCTAA
ATGATCAAGACCGTTTTCCGTGGTTGGAACGAATTAATGATGCTGCTTTTAGCTTAGAGCAAAAAAATGAAGTGGGGATT
ATTGTTTGTTCGGCGTTGAAAAAGAAATATCGTGACCAAATTCGTCAAGGTAATAGGAATGTGAAGTTTATTCATTTACA
CGGTTCATTTGAGCTGATTTTAGAACGCATGAAAAAGCGTAAAGGCCATTTTATGAAAACAGAAATGTTGAAAAGCCAGT
TTGATACGTTAGAAATTCCGCAAGAGGACGAACCGGATGTCATTTCGATTGATATTAGCGGCAGTTTTGAAGACGTGGTG
CAATTATGCGTACAGGCGATTAAAGCCTATCTATAA

Upstream 100 bases:

>100_bases
TTAATTTTAAAAATGAGATCTATATCACAAATTTTAATGTTACCTGTAACATTAAGCGGAAAAATCTGCTATGTTGCCGA
ATAAATAGGAGGAAGCTTAA

Downstream 100 bases:

>100_bases
AAAGAATGTTGAGTAGAACAAGCGGTTATTTTCTGCAAATTTTTTGCGAAATTTGACCGCTTTTTTATCGCCTAAATTGT
TTCACCGGTATGAATTTTAT

Product: thermosensitive gluconokinase

Products: NA

Alternate protein names: Gluconate kinase 1 [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MKSGQSFILMGVSSTGKTTIGSEVARRLGIKLIDGDDLHPRANILKMSQGQPLNDQDRFPWLERINDAAFSLEQKNEVGI
IVCSALKKKYRDQIRQGNRNVKFIHLHGSFELILERMKKRKGHFMKTEMLKSQFDTLEIPQEDEPDVISIDISGSFEDVV
QLCVQAIKAYL

Sequences:

>Translated_171_residues
MKSGQSFILMGVSSTGKTTIGSEVARRLGIKLIDGDDLHPRANILKMSQGQPLNDQDRFPWLERINDAAFSLEQKNEVGI
IVCSALKKKYRDQIRQGNRNVKFIHLHGSFELILERMKKRKGHFMKTEMLKSQFDTLEIPQEDEPDVISIDISGSFEDVV
QLCVQAIKAYL
>Mature_171_residues
MKSGQSFILMGVSSTGKTTIGSEVARRLGIKLIDGDDLHPRANILKMSQGQPLNDQDRFPWLERINDAAFSLEQKNEVGI
IVCSALKKKYRDQIRQGNRNVKFIHLHGSFELILERMKKRKGHFMKTEMLKSQFDTLEIPQEDEPDVISIDISGSFEDVV
QLCVQAIKAYL

Specific function: Gluconate utilization system GNT-II. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=186, Percent_Identity=38.7096774193548, Blast_Score=138, Evalue=3e-33,
Organism=Escherichia coli, GI1790719, Length=167, Percent_Identity=59.2814371257485, Blast_Score=211, Evalue=2e-56,
Organism=Escherichia coli, GI87082265, Length=162, Percent_Identity=54.320987654321, Blast_Score=194, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI25146487, Length=174, Percent_Identity=36.7816091954023, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320454, Length=170, Percent_Identity=40.5882352941176, Blast_Score=128, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 19449; Mature: 19449

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSGQSFILMGVSSTGKTTIGSEVARRLGIKLIDGDDLHPRANILKMSQGQPLNDQDRFP
CCCCCEEEEEEECCCCCCHHHHHHHHHHCCEEECCCCCCCCHHEEECCCCCCCCCCCCCC
WLERINDAAFSLEQKNEVGIIVCSALKKKYRDQIRQGNRNVKFIHLHGSFELILERMKKR
HHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHH
KGHFMKTEMLKSQFDTLEIPQEDEPDVISIDISGSFEDVVQLCVQAIKAYL
CCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSGQSFILMGVSSTGKTTIGSEVARRLGIKLIDGDDLHPRANILKMSQGQPLNDQDRFP
CCCCCEEEEEEECCCCCCHHHHHHHHHHCCEEECCCCCCCCHHEEECCCCCCCCCCCCCC
WLERINDAAFSLEQKNEVGIIVCSALKKKYRDQIRQGNRNVKFIHLHGSFELILERMKKR
HHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHH
KGHFMKTEMLKSQFDTLEIPQEDEPDVISIDISGSFEDVVQLCVQAIKAYL
CCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]