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The map label for this gene is trkH [H]

Identifier: 126209054

GI number: 126209054

Start: 1817884

End: 1819362

Strand: Direct

Name: trkH [H]

Synonym: APL_1590

Alternate gene names: 126209054

Gene position: 1817884-1819362 (Clockwise)

Preceding gene: 126209053

Following gene: 126209055

Centisome position: 79.93

GC content: 43.41

Gene sequence:

>1479_bases
GTGCAATTCTTATCAATTCTTCGTATTGTCGGCATTCTTGTGATGAGCTTTTCATTTACGATGCTCTTACCTGCCTTCGT
CGCGCTTATTTATGGCGACGGCGGCGGTCGAGAATTCCTACAATCGTTTTTACTGACGTTTAGCGTCGGGACTCTACTCT
GGTGGTTTAGCCGTAACCAAAAAAATGAACTGCGCTCGCGAGAAGGCTTTTTAATCGTGGTACTGTTCTGGGTGGTATTA
GGTTCGCTCGGGGCGGTGCCGTTTATTATTTTAGAACATCCCGATCTGAATTTTAGCGAATCGATTTTCGAATCTTTTTC
CGGGCTGACCACAACCGGTGCGACCGTGATTACCGGTTTAGACGATTTGCCGAAAGCAATTCTTTTTTACCGCCAATTTT
TACAATGGCTAGGCGGTATGGGGATCATCGTATTGGCGATTGCGATTATTCCGCTTATCGGTTTAGGTAAACTCTACCGT
GCGGAAATGCCGGGGCCGTTAAAAGACCAAAAAATGCGCCCTCGTATCGCCGAAATCTCTAAATTGCTGTGGCAAATTTA
CCTTAGCTTAACCGTTTTATGCGCACTTGCGTTTAAAATTGCGGGAATGAGTTGGTTTGATGCGATTTGTCATAGCTTTG
CCACGATTTCGATTGGCGGTTTTTCTACGCACGACGCCAGCATCGGTTATTTTGACAGCATTGTGATTAATAGCATTACC
GCCGTATTTTTACTGATTTCATCAATTAACTTCGGCTTACATTTTGCCTTAATCGATCAATTGAAAGATAAAAATAACAA
ACAAACCGGCAATATATTCAAACGACTCTATTGGAAAGACTATGAGTTTCGTTCATTTGCCGTGATCCAATTAAGCCTGT
TTTTGATTTGTTTTGCCATTTTAAGTATTTATAACTATTTTGATAATGCCGAAATCACCTTCCAACACGCGTTGTTTCAA
TCGGTATCGATTTCAACCACCGCAGGTTTTACCACCAATGATTTTAGCCAATGGCCGTCTTTTTTACCGATCTTATTGGT
GATGGCATCCTTTATCGGCGGTTGTGCCGGCTCGACCGGCGGCGGATTAAAAGTGATTCGGGTAATGTTGTTATACTTAC
AAGCAAACCGAGAAATTCACCGTTTCGTCCACCCTAATTCGGTTAAACCGATCAAACTCGGTGCGCATATTTTCTCGGAG
CGTATCGAAGAAGGTATTTGGGCTTTCTTTTCCGCTTATATTTTTGTGTTCGTAATGTGTTGGTTCGGCACCATTGCCTT
CGGTATGGAAACGTTTGACGCCTTTAATGCGGTGGTCGCTTCACTCAATAATCTCGGGCCGGCATTAGGCAATGTCAGCA
GTAACTTTACCCAAGTGCCGGACGGTGCCAAATGGGTACTCACTATCGCGATGGTATGCGGGCGTTTAGAAGTGTTTACT
CTCTTAGTTATTTTAAGTCCGGTATTCTGGAAAGATTAA

Upstream 100 bases:

>100_bases
ACCTTGCGAATCATTCATAACCATTGACTTTTTTGCTAAAATCTCACGAAATTTAACCGCTTACCTTCGGGCAAATGCAC
CCGATTCATTTGAGGTCTTT

Downstream 100 bases:

>100_bases
CATGGAATAAATCAATGAAAACTCTCATTCTCTATTTTACGACCGACGGTCAAACCAAACGTATTGCGGAAAAAATAGCG
CAAGAAATCACTCACGAAAC

Product: Trk system potassium uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MQFLSILRIVGILVMSFSFTMLLPAFVALIYGDGGGREFLQSFLLTFSVGTLLWWFSRNQKNELRSREGFLIVVLFWVVL
GSLGAVPFIILEHPDLNFSESIFESFSGLTTTGATVITGLDDLPKAILFYRQFLQWLGGMGIIVLAIAIIPLIGLGKLYR
AEMPGPLKDQKMRPRIAEISKLLWQIYLSLTVLCALAFKIAGMSWFDAICHSFATISIGGFSTHDASIGYFDSIVINSIT
AVFLLISSINFGLHFALIDQLKDKNNKQTGNIFKRLYWKDYEFRSFAVIQLSLFLICFAILSIYNYFDNAEITFQHALFQ
SVSISTTAGFTTNDFSQWPSFLPILLVMASFIGGCAGSTGGGLKVIRVMLLYLQANREIHRFVHPNSVKPIKLGAHIFSE
RIEEGIWAFFSAYIFVFVMCWFGTIAFGMETFDAFNAVVASLNNLGPALGNVSSNFTQVPDGAKWVLTIAMVCGRLEVFT
LLVILSPVFWKD

Sequences:

>Translated_492_residues
MQFLSILRIVGILVMSFSFTMLLPAFVALIYGDGGGREFLQSFLLTFSVGTLLWWFSRNQKNELRSREGFLIVVLFWVVL
GSLGAVPFIILEHPDLNFSESIFESFSGLTTTGATVITGLDDLPKAILFYRQFLQWLGGMGIIVLAIAIIPLIGLGKLYR
AEMPGPLKDQKMRPRIAEISKLLWQIYLSLTVLCALAFKIAGMSWFDAICHSFATISIGGFSTHDASIGYFDSIVINSIT
AVFLLISSINFGLHFALIDQLKDKNNKQTGNIFKRLYWKDYEFRSFAVIQLSLFLICFAILSIYNYFDNAEITFQHALFQ
SVSISTTAGFTTNDFSQWPSFLPILLVMASFIGGCAGSTGGGLKVIRVMLLYLQANREIHRFVHPNSVKPIKLGAHIFSE
RIEEGIWAFFSAYIFVFVMCWFGTIAFGMETFDAFNAVVASLNNLGPALGNVSSNFTQVPDGAKWVLTIAMVCGRLEVFT
LLVILSPVFWKD
>Mature_492_residues
MQFLSILRIVGILVMSFSFTMLLPAFVALIYGDGGGREFLQSFLLTFSVGTLLWWFSRNQKNELRSREGFLIVVLFWVVL
GSLGAVPFIILEHPDLNFSESIFESFSGLTTTGATVITGLDDLPKAILFYRQFLQWLGGMGIIVLAIAIIPLIGLGKLYR
AEMPGPLKDQKMRPRIAEISKLLWQIYLSLTVLCALAFKIAGMSWFDAICHSFATISIGGFSTHDASIGYFDSIVINSIT
AVFLLISSINFGLHFALIDQLKDKNNKQTGNIFKRLYWKDYEFRSFAVIQLSLFLICFAILSIYNYFDNAEITFQHALFQ
SVSISTTAGFTTNDFSQWPSFLPILLVMASFIGGCAGSTGGGLKVIRVMLLYLQANREIHRFVHPNSVKPIKLGAHIFSE
RIEEGIWAFFSAYIFVFVMCWFGTIAFGMETFDAFNAVVASLNNLGPALGNVSSNFTQVPDGAKWVLTIAMVCGRLEVFT
LLVILSPVFWKD

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=494, Percent_Identity=59.7165991902834, Blast_Score=550, Evalue=1e-158,
Organism=Escherichia coli, GI1787626, Length=490, Percent_Identity=36.734693877551, Blast_Score=340, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 54923; Mature: 54923

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFLSILRIVGILVMSFSFTMLLPAFVALIYGDGGGREFLQSFLLTFSVGTLLWWFSRNQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
KNELRSREGFLIVVLFWVVLGSLGAVPFIILEHPDLNFSESIFESFSGLTTTGATVITGL
HHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHCC
DDLPKAILFYRQFLQWLGGMGIIVLAIAIIPLIGLGKLYRAEMPGPLKDQKMRPRIAEIS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHHHHH
KLLWQIYLSLTVLCALAFKIAGMSWFDAICHSFATISIGGFSTHDASIGYFDSIVINSIT
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHH
AVFLLISSINFGLHFALIDQLKDKNNKQTGNIFKRLYWKDYEFRSFAVIQLSLFLICFAI
HHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LSIYNYFDNAEITFQHALFQSVSISTTAGFTTNDFSQWPSFLPILLVMASFIGGCAGSTG
HHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
GGLKVIRVMLLYLQANREIHRFVHPNSVKPIKLGAHIFSERIEEGIWAFFSAYIFVFVMC
CHHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFGTIAFGMETFDAFNAVVASLNNLGPALGNVSSNFTQVPDGAKWVLTIAMVCGRLEVFT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLVILSPVFWKD
HHHHHHHHHCCC
>Mature Secondary Structure
MQFLSILRIVGILVMSFSFTMLLPAFVALIYGDGGGREFLQSFLLTFSVGTLLWWFSRNQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
KNELRSREGFLIVVLFWVVLGSLGAVPFIILEHPDLNFSESIFESFSGLTTTGATVITGL
HHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHCC
DDLPKAILFYRQFLQWLGGMGIIVLAIAIIPLIGLGKLYRAEMPGPLKDQKMRPRIAEIS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCHHHHHH
KLLWQIYLSLTVLCALAFKIAGMSWFDAICHSFATISIGGFSTHDASIGYFDSIVINSIT
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHH
AVFLLISSINFGLHFALIDQLKDKNNKQTGNIFKRLYWKDYEFRSFAVIQLSLFLICFAI
HHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LSIYNYFDNAEITFQHALFQSVSISTTAGFTTNDFSQWPSFLPILLVMASFIGGCAGSTG
HHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
GGLKVIRVMLLYLQANREIHRFVHPNSVKPIKLGAHIFSERIEEGIWAFFSAYIFVFVMC
CHHHHHHHHHHHHHHCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WFGTIAFGMETFDAFNAVVASLNNLGPALGNVSSNFTQVPDGAKWVLTIAMVCGRLEVFT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLVILSPVFWKD
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]