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The map label for this gene is anmK

Identifier: 126208999

GI number: 126208999

Start: 1749433

End: 1750542

Strand: Direct

Name: anmK

Synonym: APL_1535

Alternate gene names: 126208999

Gene position: 1749433-1750542 (Clockwise)

Preceding gene: 126208996

Following gene: 126209000

Centisome position: 76.92

GC content: 46.22

Gene sequence:

>1110_bases
ATGACTAAAAACCTCTACCTCGGCGTGATGTCCGGCACCAGCCTTGACGGCGTGGATTTATGTGTGATGGACTTTGCAAA
AAATCCGCCAAAATTGACCGCTTGCGGCTTTACCCCAATGCCGGAAGATTTACGCACCGATTTATCGCACTTACTCAAAA
GCGGAGAAACTTCCTTACAAAAGTTAGGTGAAATCGATCACCGTTTAGGCTTGCTGTATGCCGAAAGTATCAAGCGTTTT
TTAGCCGAACATCAACTCAGTGCAAGTGATATTCAGGCAATCGGCTGTCACGGACAAACTGTCTGGCATTCTCCAAACGG
CAACTTCCCGTTTACTATGCAAATCGGCGATATGAATTTGGTTGCCGCTCATACCGGCATTACTACTATTGCAGATTTCC
GTCGTAAAGATATGGCAGTCGGCGGACAAGGCGCACCATTAGTGCCTGCTTTTCACGAAGGGATTTTTGCCTCGCCGGAA
CGCTTAACCGTAGTGCTGAACATCGGCGGTATTTCCAATATTTCGGTACTTGCGCCACAGCAGCCGACAATCGGCTACGA
TGTCAGTGTCGGTAATGCACTGATGGATTCGTGGATAGAGCTGCACCAAGCTAAACGCTATGACAAAAATGCCGAATGGG
CAAAAACCGGAACACTGATTCCGGCATTGCTCGACAGTCTGCTTGACGAGCCTTTTTTCAAATTACCTGCCCCGAAAAGC
ACCGGACGAGAATTATTTAATCTCGAATGGCTTGCAAAAAAATCGGCAAATTTAACCGCTTATCGTCCTGAAGACGTACA
GCGTACATTGGCGGAATTTACCGTACAAAGTGTAGTAAACGAACTAAAAACCTTAGAAAGTGAAAAGCAATGCTTGTTAC
TTGCTTGTGGTGGTGGCGCACGCAACCCATTGTTAATGCAGAGATTTTCAGAATTACTGCCAAAATGGCAGGTGGCTACC
ACCGATGAGTACGGATTGGATATTGATTATGTCGAAGCAGCTGCTTTTGCCTGGCTGGCTTATCAACGAGTGCATAATTT
AACGAACAACTTACCAAGCGTAACCGGAGCAAAAGAGCCGGTGAGTTTAGGGGTAATTTATCCTAAGTAA

Upstream 100 bases:

>100_bases
GTTCATAAAGCGATAAATTTGTAAAAATCAGCCGAGATCTTACCGCTTTTATGCCGGATATTCGATATAATTCAACAAAT
TTTCCTTTTATCTCACTTTT

Downstream 100 bases:

>100_bases
TCACTTCCTCACTTGTATAAAACACCAAAAGTAAAAGGTGGTTGGAGATAAAAATGTCAGAAAAAAATTTATTAACCGCG
TTGTCAAAAATGATTACCGA

Product: anhydro-N-acetylmuramic acid kinase

Products: NA

Alternate protein names: AnhMurNAc kinase

Number of amino acids: Translated: 369; Mature: 368

Protein sequence:

>369_residues
MTKNLYLGVMSGTSLDGVDLCVMDFAKNPPKLTACGFTPMPEDLRTDLSHLLKSGETSLQKLGEIDHRLGLLYAESIKRF
LAEHQLSASDIQAIGCHGQTVWHSPNGNFPFTMQIGDMNLVAAHTGITTIADFRRKDMAVGGQGAPLVPAFHEGIFASPE
RLTVVLNIGGISNISVLAPQQPTIGYDVSVGNALMDSWIELHQAKRYDKNAEWAKTGTLIPALLDSLLDEPFFKLPAPKS
TGRELFNLEWLAKKSANLTAYRPEDVQRTLAEFTVQSVVNELKTLESEKQCLLLACGGGARNPLLMQRFSELLPKWQVAT
TDEYGLDIDYVEAAAFAWLAYQRVHNLTNNLPSVTGAKEPVSLGVIYPK

Sequences:

>Translated_369_residues
MTKNLYLGVMSGTSLDGVDLCVMDFAKNPPKLTACGFTPMPEDLRTDLSHLLKSGETSLQKLGEIDHRLGLLYAESIKRF
LAEHQLSASDIQAIGCHGQTVWHSPNGNFPFTMQIGDMNLVAAHTGITTIADFRRKDMAVGGQGAPLVPAFHEGIFASPE
RLTVVLNIGGISNISVLAPQQPTIGYDVSVGNALMDSWIELHQAKRYDKNAEWAKTGTLIPALLDSLLDEPFFKLPAPKS
TGRELFNLEWLAKKSANLTAYRPEDVQRTLAEFTVQSVVNELKTLESEKQCLLLACGGGARNPLLMQRFSELLPKWQVAT
TDEYGLDIDYVEAAAFAWLAYQRVHNLTNNLPSVTGAKEPVSLGVIYPK
>Mature_368_residues
TKNLYLGVMSGTSLDGVDLCVMDFAKNPPKLTACGFTPMPEDLRTDLSHLLKSGETSLQKLGEIDHRLGLLYAESIKRFL
AEHQLSASDIQAIGCHGQTVWHSPNGNFPFTMQIGDMNLVAAHTGITTIADFRRKDMAVGGQGAPLVPAFHEGIFASPER
LTVVLNIGGISNISVLAPQQPTIGYDVSVGNALMDSWIELHQAKRYDKNAEWAKTGTLIPALLDSLLDEPFFKLPAPKST
GRELFNLEWLAKKSANLTAYRPEDVQRTLAEFTVQSVVNELKTLESEKQCLLLACGGGARNPLLMQRFSELLPKWQVATT
DEYGLDIDYVEAAAFAWLAYQRVHNLTNNLPSVTGAKEPVSLGVIYPK

Specific function: Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived

COG id: COG2377

COG function: function code O; Predicted molecular chaperone distantly related to HSP70-fold metalloproteases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anhydro-N-acetylmuramic acid kinase family

Homologues:

Organism=Escherichia coli, GI1787928, Length=368, Percent_Identity=48.6413043478261, Blast_Score=344, Evalue=7e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ANMK_ACTP2 (A3N2I3)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054224.1
- ProteinModelPortal:   A3N2I3
- SMR:   A3N2I3
- STRING:   A3N2I3
- GeneID:   4849027
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1535
- eggNOG:   COG2377
- HOGENOM:   HBG324434
- OMA:   GSHGQTV
- PhylomeDB:   A3N2I3
- ProtClustDB:   PRK09585
- BioCyc:   APLE416269:APL_1535-MONOMER
- HAMAP:   MF_01270
- InterPro:   IPR005338

Pfam domain/function: PF03702 UPF0075

EC number: NA

Molecular weight: Translated: 40455; Mature: 40324

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNLYLGVMSGTSLDGVDLCVMDFAKNPPKLTACGFTPMPEDLRTDLSHLLKSGETSLQ
CCCCEEEEEECCCCCCCHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHCCHHHHH
KLGEIDHRLGLLYAESIKRFLAEHQLSASDIQAIGCHGQTVWHSPNGNFPFTMQIGDMNL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCEEEECCCCCCCEEEEECCEEE
VAAHTGITTIADFRRKDMAVGGQGAPLVPAFHEGIFASPERLTVVLNIGGISNISVLAPQ
EEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEEEEECCCCCEEEECCC
QPTIGYDVSVGNALMDSWIELHQAKRYDKNAEWAKTGTLIPALLDSLLDEPFFKLPAPKS
CCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHCCCCEECCCCCC
TGRELFNLEWLAKKSANLTAYRPEDVQRTLAEFTVQSVVNELKTLESEKQCLLLACGGGA
CCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
RNPLLMQRFSELLPKWQVATTDEYGLDIDYVEAAAFAWLAYQRVHNLTNNLPSVTGAKEP
CCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VSLGVIYPK
CEEEEEECC
>Mature Secondary Structure 
TKNLYLGVMSGTSLDGVDLCVMDFAKNPPKLTACGFTPMPEDLRTDLSHLLKSGETSLQ
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHCCHHHHH
KLGEIDHRLGLLYAESIKRFLAEHQLSASDIQAIGCHGQTVWHSPNGNFPFTMQIGDMNL
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCEEEECCCCCCCEEEEECCEEE
VAAHTGITTIADFRRKDMAVGGQGAPLVPAFHEGIFASPERLTVVLNIGGISNISVLAPQ
EEECCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEEEEECCCCCEEEECCC
QPTIGYDVSVGNALMDSWIELHQAKRYDKNAEWAKTGTLIPALLDSLLDEPFFKLPAPKS
CCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHCCCCEECCCCCC
TGRELFNLEWLAKKSANLTAYRPEDVQRTLAEFTVQSVVNELKTLESEKQCLLLACGGGA
CCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
RNPLLMQRFSELLPKWQVATTDEYGLDIDYVEAAAFAWLAYQRVHNLTNNLPSVTGAKEP
CCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VSLGVIYPK
CEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA