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The map label for this gene is frdD

Identifier: 126208990

GI number: 126208990

Start: 1740789

End: 1741133

Strand: Reverse

Name: frdD

Synonym: APL_1526

Alternate gene names: 126208990

Gene position: 1741133-1740789 (Counterclockwise)

Preceding gene: 126208991

Following gene: 126208989

Centisome position: 76.55

GC content: 44.06

Gene sequence:

>345_bases
ATGAATAAACAAGATCCAAAACGTTCTAACGAACCGCCTGTATGGTTAATGTTTAGTGCGGGCGGTACAATCAGCGCAAT
TTGCTTCCCGGTATTACTTCTTATTTTAGGTGTGTTATTACCGCTCGGTTTAGTGCCGGTGGAGAATATTGTGGCGTTTG
CTCACACTTGGTTCGGTAAATTAGTGATTTTAGCGGTAACTATTTTCCCAATGTGGGCGGGTATGCACCGTGTACATCAC
GGTTTACATGACCTCAAAATTCACTTTCCTGCGGGTGGCTGGGTATTCTACGGATTATCCGCTCTCTACTCAGTGATTGT
GTTCTTTGCAGTAATCGCACTGTAA

Upstream 100 bases:

>100_bases
GCGCGTAAATCCGAATATTTTAAAAAATGCACTTTGGGCGGTAACAGGTTTAGTAAGCCTTGTTGCATTAGTATGTACTT
ATATCTAGGGGAGAATGGCA

Downstream 100 bases:

>100_bases
TCAATATAACGTGAATAAAAGCCATCCGTCAGGGTGGCTTTTTTTGTCGTATAAGCGGTTGAATTTTTAGGAAATCTTGC
AAAGCCATTTCTTTAAAATA

Product: fumarate reductase subunit D

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MNKQDPKRSNEPPVWLMFSAGGTISAICFPVLLLILGVLLPLGLVPVENIVAFAHTWFGKLVILAVTIFPMWAGMHRVHH
GLHDLKIHFPAGGWVFYGLSALYSVIVFFAVIAL

Sequences:

>Translated_114_residues
MNKQDPKRSNEPPVWLMFSAGGTISAICFPVLLLILGVLLPLGLVPVENIVAFAHTWFGKLVILAVTIFPMWAGMHRVHH
GLHDLKIHFPAGGWVFYGLSALYSVIVFFAVIAL
>Mature_114_residues
MNKQDPKRSNEPPVWLMFSAGGTISAICFPVLLLILGVLLPLGLVPVENIVAFAHTWFGKLVILAVTIFPMWAGMHRVHH
GLHDLKIHFPAGGWVFYGLSALYSVIVFFAVIAL

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane

COG id: COG3080

COG function: function code C; Fumarate reductase subunit D

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdD family

Homologues:

Organism=Escherichia coli, GI1790594, Length=119, Percent_Identity=47.0588235294118, Blast_Score=120, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRDD_ACTP2 (A3N2H4)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054215.1
- ProteinModelPortal:   A3N2H4
- SMR:   A3N2H4
- STRING:   A3N2H4
- GeneID:   4850090
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1526
- eggNOG:   COG3080
- HOGENOM:   HBG297136
- OMA:   HRIHHGM
- PhylomeDB:   A3N2H4
- ProtClustDB:   PRK05470
- BioCyc:   APLE416269:APL_1526-MONOMER
- HAMAP:   MF_00709
- InterPro:   IPR003418
- ProDom:   PD015693

Pfam domain/function: PF02313 Fumarate_red_D

EC number: 1.3.99.1

Molecular weight: Translated: 12563; Mature: 12563

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1c297f70)-; HASH(0x1e4f0058)-; HASH(0x1e849d14)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQDPKRSNEPPVWLMFSAGGTISAICFPVLLLILGVLLPLGLVPVENIVAFAHTWFGK
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LVILAVTIFPMWAGMHRVHHGLHDLKIHFPAGGWVFYGLSALYSVIVFFAVIAL
HHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MNKQDPKRSNEPPVWLMFSAGGTISAICFPVLLLILGVLLPLGLVPVENIVAFAHTWFGK
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LVILAVTIFPMWAGMHRVHHGLHDLKIHFPAGGWVFYGLSALYSVIVFFAVIAL
HHHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA