Click here to switch to the map view.

The map label for this gene is lspA [H]

Identifier: 126208983

GI number: 126208983

Start: 1734123

End: 1734605

Strand: Direct

Name: lspA [H]

Synonym: APL_1519

Alternate gene names: 126208983

Gene position: 1734123-1734605 (Clockwise)

Preceding gene: 126208982

Following gene: 126208984

Centisome position: 76.24

GC content: 39.96

Gene sequence:

>483_bases
ATGAAACAAACCGGAATCAAATGGTTGTGGCTGAGTTTAGCGACGATTATTATTGATCTATGGACCAAATACCTTGTAGT
ACAACGCTTTGAGTTATATGAAAGCGTAAACGTATTGCCCGTTTTTAATTTAACTTATGTACGCAACTACGGTGCGGCAT
TCAGCTTTTTGGCTGATCACGGCGGTTGGCAGAAATATTTCTTCTTAGGATTAGCCGTTGTTATTTCACTGGGTTTAATC
GTGATGCTGTGGCGTAATCACGCGGTCAAAAAATTAGAAAATTCTGCGTATGCCCTGATTATCGGCGGTGCAATCGGTAA
TGCGATTGATCGTGCTTATAACGGCTATGTAGTTGATTTCTTTGATTTTTACTGGGATATTTATCATTATCCCGTATTTA
ATGTGGCGGATATTGCCATTGTAGTGGGTGCGGGTTTGCTCATCTTGGAAGCATTCCTCGACAAAAAGAAAAAGAGTGAT
TAA

Upstream 100 bases:

>100_bases
AGAAAACGAAGACGCACTTTAACCGTTTTTAGCGATGTTACCCTCTCAGAGAGAGGCGGCATACAACCAGACACACGATT
AACATTCAAATAGGAAAACT

Downstream 100 bases:

>100_bases
ATGAATATTTTATTAGCAAACCCAAGAGGGTTCTGTGCCGGCGTTGATCGAGCGATTTCGATTGTGGAACTTGCCCTTGA
AATTCACGGCGCACCGATTT

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKQTGIKWLWLSLATIIIDLWTKYLVVQRFELYESVNVLPVFNLTYVRNYGAAFSFLADHGGWQKYFFLGLAVVISLGLI
VMLWRNHAVKKLENSAYALIIGGAIGNAIDRAYNGYVVDFFDFYWDIYHYPVFNVADIAIVVGAGLLILEAFLDKKKKSD

Sequences:

>Translated_160_residues
MKQTGIKWLWLSLATIIIDLWTKYLVVQRFELYESVNVLPVFNLTYVRNYGAAFSFLADHGGWQKYFFLGLAVVISLGLI
VMLWRNHAVKKLENSAYALIIGGAIGNAIDRAYNGYVVDFFDFYWDIYHYPVFNVADIAIVVGAGLLILEAFLDKKKKSD
>Mature_160_residues
MKQTGIKWLWLSLATIIIDLWTKYLVVQRFELYESVNVLPVFNLTYVRNYGAAFSFLADHGGWQKYFFLGLAVVISLGLI
VMLWRNHAVKKLENSAYALIIGGAIGNAIDRAYNGYVVDFFDFYWDIYHYPVFNVADIAIVVGAGLLILEAFLDKKKKSD

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=158, Percent_Identity=55.0632911392405, Blast_Score=181, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 18285; Mature: 18285

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTGIKWLWLSLATIIIDLWTKYLVVQRFELYESVNVLPVFNLTYVRNYGAAFSFLADH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHC
GGWQKYFFLGLAVVISLGLIVMLWRNHAVKKLENSAYALIIGGAIGNAIDRAYNGYVVDF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCEEEHH
FDFYWDIYHYPVFNVADIAIVVGAGLLILEAFLDKKKKSD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKQTGIKWLWLSLATIIIDLWTKYLVVQRFELYESVNVLPVFNLTYVRNYGAAFSFLADH
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHC
GGWQKYFFLGLAVVISLGLIVMLWRNHAVKKLENSAYALIIGGAIGNAIDRAYNGYVVDF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCEEEHH
FDFYWDIYHYPVFNVADIAIVVGAGLLILEAFLDKKKKSD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA