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The map label for this gene is mogA [H]

Identifier: 126208981

GI number: 126208981

Start: 1733002

End: 1733586

Strand: Direct

Name: mogA [H]

Synonym: APL_1517

Alternate gene names: 126208981

Gene position: 1733002-1733586 (Clockwise)

Preceding gene: 126208980

Following gene: 126208982

Centisome position: 76.19

GC content: 47.52

Gene sequence:

>585_bases
ATGTTAAGTAAAGAGACATTAAAAATCGGTTTGGTTTCCGTTTCGGACCGTGCCTCCGGCGGCGTTTACCAAGACCAAGG
TATTCCCGAATTACAAGCGTGGTTGGAATCCGTATTAACCGCCCCGTTTGAAGTGGAAACACGTTTAATTCCGGACGAGC
AAGCTATCATTGAGCAAACATTAATTGAATTGGTGGATACGCACCACTGCCATTTAGTCTTAACCACCGGCGGTACCGGA
CCGGCAAAACGAGACGTCACGCCGGATGCGACCCTTGCGGTGGCACATCGTGAAATGCCGGGCTTTGGCGAACAAATGCG
TCAAGTAAGCTTGCATTTCGTACCGACCGCAATTCTTTCTCGCCAAGTCGGTGTTATTCGTCACGACTCGCTAATTTTAA
ATTTACCGGGGCAGCCGAAAGCAATTAAAGAAACTCTTGAAGGGGTAAAAGACGCACAAGGTAATACGCTGGTACGAGGC
GTTTTTAGTGCCGTGCCGTACTGTCTGCAATTATTGAGCGAAATTTATATCGACACTCACCCTGAAATCTGCGAAAGTTT
CCGTCCGAAATCAGCAAGAAGATAA

Upstream 100 bases:

>100_bases
AACCGGCTAAAGCGGAAGAGAAAAAATAATAACATTTTAGCGAACTAAAAACTGATTCGGGCGGGTTTATACCCGCCCTA
AAATTGCAAAAGGATAAATA

Downstream 100 bases:

>100_bases
TCTTTAAAACCACGGAGCACCTGATAACTCGGAAAACTAAACAAGCGGTCAAATTTACTGAAAATTTTACATTCCGAGTA
ATCTGCGTTATCCGCGGTGA

Product: molybdenum cofactor biosynthesis protein MogA

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MLSKETLKIGLVSVSDRASGGVYQDQGIPELQAWLESVLTAPFEVETRLIPDEQAIIEQTLIELVDTHHCHLVLTTGGTG
PAKRDVTPDATLAVAHREMPGFGEQMRQVSLHFVPTAILSRQVGVIRHDSLILNLPGQPKAIKETLEGVKDAQGNTLVRG
VFSAVPYCLQLLSEIYIDTHPEICESFRPKSARR

Sequences:

>Translated_194_residues
MLSKETLKIGLVSVSDRASGGVYQDQGIPELQAWLESVLTAPFEVETRLIPDEQAIIEQTLIELVDTHHCHLVLTTGGTG
PAKRDVTPDATLAVAHREMPGFGEQMRQVSLHFVPTAILSRQVGVIRHDSLILNLPGQPKAIKETLEGVKDAQGNTLVRG
VFSAVPYCLQLLSEIYIDTHPEICESFRPKSARR
>Mature_194_residues
MLSKETLKIGLVSVSDRASGGVYQDQGIPELQAWLESVLTAPFEVETRLIPDEQAIIEQTLIELVDTHHCHLVLTTGGTG
PAKRDVTPDATLAVAHREMPGFGEQMRQVSLHFVPTAILSRQVGVIRHDSLILNLPGQPKAIKETLEGVKDAQGNTLVRG
VFSAVPYCLQLLSEIYIDTHPEICESFRPKSARR

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=173, Percent_Identity=34.1040462427746, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI10880983, Length=173, Percent_Identity=34.1040462427746, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1786190, Length=189, Percent_Identity=78.8359788359788, Blast_Score=315, Evalue=1e-87,
Organism=Caenorhabditis elegans, GI17564954, Length=144, Percent_Identity=36.1111111111111, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI17136978, Length=145, Percent_Identity=35.1724137931034, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24638841, Length=145, Percent_Identity=35.1724137931034, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 21313; Mature: 21313

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKETLKIGLVSVSDRASGGVYQDQGIPELQAWLESVLTAPFEVETRLIPDEQAIIEQT
CCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
LIELVDTHHCHLVLTTGGTGPAKRDVTPDATLAVAHREMPGFGEQMRQVSLHFVPTAILS
HHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHEEHHHCCCCHHHHHHHHHHHHHHHHHHH
RQVGVIRHDSLILNLPGQPKAIKETLEGVKDAQGNTLVRGVFSAVPYCLQLLSEIYIDTH
HHCCEEEECCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PEICESFRPKSARR
HHHHHHCCCCCCCC
>Mature Secondary Structure
MLSKETLKIGLVSVSDRASGGVYQDQGIPELQAWLESVLTAPFEVETRLIPDEQAIIEQT
CCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
LIELVDTHHCHLVLTTGGTGPAKRDVTPDATLAVAHREMPGFGEQMRQVSLHFVPTAILS
HHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHEEHHHCCCCHHHHHHHHHHHHHHHHHHH
RQVGVIRHDSLILNLPGQPKAIKETLEGVKDAQGNTLVRGVFSAVPYCLQLLSEIYIDTH
HHCCEEEECCEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PEICESFRPKSARR
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]