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The map label for this gene is holC [H]

Identifier: 126208969

GI number: 126208969

Start: 1721997

End: 1722434

Strand: Reverse

Name: holC [H]

Synonym: APL_1505

Alternate gene names: 126208969

Gene position: 1722434-1721997 (Counterclockwise)

Preceding gene: 126208976

Following gene: 126208968

Centisome position: 75.73

GC content: 46.12

Gene sequence:

>438_bases
ATGAAACAAGTTAAATTTTACCTGTTAAGCCAGACGGAACGGGAAAACCTTTCCGCCGCTGAGACAATGGCGTGTGATTT
GGCGGCGAATGCATGGCGTTTGGGTAAACGTGTGCTGATTGCCTGCGAAACCGAACAGCAAGCCTTGAATATCGACGAAG
CGTTATGGGCAAGAGATCCCGATTCGTTTGTGCCGCATAATCTTTCCGGTGAAGTAACACAATATGCCACACCGATAGAA
ATCTCGTGGAAAGGTAAACGTAATGCACAACGCCGAGATGTATTGATTTCGTTACAAACAGCCGTGCCGGATTTTATCAA
CAGTTTTAATCAGATTATTGATTTCGTGCCGGCAAATGAAACGGAAAAAGTACAGGCACGCGAGCGTTACAAACAGTACC
GCCAACTGGGTTGGCAATTGGAAACGGAACAAGCGTAA

Upstream 100 bases:

>100_bases
TGCAAAAAAACGAGTAAAACTTACCGCTTACATTTCAAATTTTCCTCATTTTCGGATAAAATCTTACTCTTTTGTATTCT
TTTCTATTCAGGGCTAGGCA

Downstream 100 bases:

>100_bases
ATGTGGTATTGCAAAACCTTTTCACAATTATCTACAAGAGAATTGTTTGAAATTTACAAGTTACGTACCGCCGTGTTTGT
AGTGGAACAAAATTGTCCTT

Product: DNA polymerase III subunit chi

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MKQVKFYLLSQTERENLSAAETMACDLAANAWRLGKRVLIACETEQQALNIDEALWARDPDSFVPHNLSGEVTQYATPIE
ISWKGKRNAQRRDVLISLQTAVPDFINSFNQIIDFVPANETEKVQARERYKQYRQLGWQLETEQA

Sequences:

>Translated_145_residues
MKQVKFYLLSQTERENLSAAETMACDLAANAWRLGKRVLIACETEQQALNIDEALWARDPDSFVPHNLSGEVTQYATPIE
ISWKGKRNAQRRDVLISLQTAVPDFINSFNQIIDFVPANETEKVQARERYKQYRQLGWQLETEQA
>Mature_145_residues
MKQVKFYLLSQTERENLSAAETMACDLAANAWRLGKRVLIACETEQQALNIDEALWARDPDSFVPHNLSGEVTQYATPIE
ISWKGKRNAQRRDVLISLQTAVPDFINSFNQIIDFVPANETEKVQARERYKQYRQLGWQLETEQA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2927

COG function: function code L; DNA polymerase III, chi subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790709, Length=143, Percent_Identity=53.8461538461538, Blast_Score=162, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007459 [H]

Pfam domain/function: PF04364 DNA_pol3_chi [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 16718; Mature: 16718

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVKFYLLSQTERENLSAAETMACDLAANAWRLGKRVLIACETEQQALNIDEALWARDP
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHCCCHHHHHCCCC
DSFVPHNLSGEVTQYATPIEISWKGKRNAQRRDVLISLQTAVPDFINSFNQIIDFVPANE
CCCCCCCCCCCCHHCCCCEEEEECCCCCCCCHHEEEEHHHHHHHHHHHHHHHHHCCCCCC
TEKVQARERYKQYRQLGWQLETEQA
CHHHHHHHHHHHHHHHCCEECCCCC
>Mature Secondary Structure
MKQVKFYLLSQTERENLSAAETMACDLAANAWRLGKRVLIACETEQQALNIDEALWARDP
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHCCCHHHHHCCCC
DSFVPHNLSGEVTQYATPIEISWKGKRNAQRRDVLISLQTAVPDFINSFNQIIDFVPANE
CCCCCCCCCCCCHHCCCCEEEEECCCCCCCCHHEEEEHHHHHHHHHHHHHHHHHCCCCCC
TEKVQARERYKQYRQLGWQLETEQA
CHHHHHHHHHHHHHHHCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 7959067 [H]