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The map label for this gene is cdd

Identifier: 126208807

GI number: 126208807

Start: 1542869

End: 1543762

Strand: Direct

Name: cdd

Synonym: APL_1343

Alternate gene names: 126208807

Gene position: 1542869-1543762 (Clockwise)

Preceding gene: 126208806

Following gene: 126208811

Centisome position: 67.83

GC content: 43.62

Gene sequence:

>894_bases
ATGCCAACTTTATTTGCACTTAAAGAACGTATCGCTCAAGTTGTTCAAGAAAAAAATGATCCTATAGTAACCGCAGTGGC
TACAACCTTAGCGGAACAACAGTACAACGCATGCTTTTCTGCGGAACAAGTAAAATTATGGAAGCGACAATTTAAATGCT
CGTCGGTTGAATTGGCGCTTGCCTGTTTACCAATTGCCGCCTGTTACGCACTTGTACCGATTTCTAACTTTTATGTGGGA
GCGGTTGCAATCGGGGAATCCGGTCGCTTTTATTTCGGGGCGAATCAAGAGTTTAACGCGCAAGCGATTCAACAAACCGT
ACATGCCGAGCAAAGTGCGATTTCCCATGCATGGCTTGCCGGTGAAACGGCGATTACCGATATGGTGGTAAACTATACGC
CTTGCGGTCATTGCCGCCAGTTTATGAACGAATTAAACAGTGCGAAAACCTTAAAAATTCATTTGCCACACAGCCAAAAT
AATTTGTTACGGCAATATTTACCGGACTCTTTCGGCCCTAAAGATCTAAATATTGAAAAGGTATTATTTGATCAACAAAC
GCATTCGCTACCGCTTCGGGGCGACTTATTAACGCAAGCGGCGATTCAAACGGCGGCACAATCTTATGCACCATATAGCA
AATCGTTAAGCGGGATTGCCTTACAAGTCGGCGAACAAATTATTTGCGGACGTTATGCGGAAAATGCGGCGTTTAACCCG
AGCTTTTTACCGTTACAAAGCGCGTTAAATTATCGCCGTTTAAGCGGTAAATCAGATGAACGGATTAGCCGTATTGTAAT
GGCGGAAAGTAAAGGCACAACCAGCCATCGCCAAATGAGCGAAGCGTTAGCGGAAAGTTTTTTAGGACTAAACCTAGAAT
ATATCGAAGTATAA

Upstream 100 bases:

>100_bases
CTTTTTAAACCTTTTATCCGATAAGTAAGATCTTCATCACTATAGGAGTGCTTATTTGCGGTTATAATAAGCCCCCGTCA
AACAGAGGAGCAAAAGCATA

Downstream 100 bases:

>100_bases
TCGCAAAAATGAAAAAAGCACCTTAGGGTGCTTTTTTATATATTGATTAGTATTTGGAACCGATTCGGAATATATGTCGA
TTAGTCGCAATTTTTGCCGA

Product: cytidine deaminase

Products: NA

Alternate protein names: Cytidine aminohydrolase; CDA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MPTLFALKERIAQVVQEKNDPIVTAVATTLAEQQYNACFSAEQVKLWKRQFKCSSVELALACLPIAACYALVPISNFYVG
AVAIGESGRFYFGANQEFNAQAIQQTVHAEQSAISHAWLAGETAITDMVVNYTPCGHCRQFMNELNSAKTLKIHLPHSQN
NLLRQYLPDSFGPKDLNIEKVLFDQQTHSLPLRGDLLTQAAIQTAAQSYAPYSKSLSGIALQVGEQIICGRYAENAAFNP
SFLPLQSALNYRRLSGKSDERISRIVMAESKGTTSHRQMSEALAESFLGLNLEYIEV

Sequences:

>Translated_297_residues
MPTLFALKERIAQVVQEKNDPIVTAVATTLAEQQYNACFSAEQVKLWKRQFKCSSVELALACLPIAACYALVPISNFYVG
AVAIGESGRFYFGANQEFNAQAIQQTVHAEQSAISHAWLAGETAITDMVVNYTPCGHCRQFMNELNSAKTLKIHLPHSQN
NLLRQYLPDSFGPKDLNIEKVLFDQQTHSLPLRGDLLTQAAIQTAAQSYAPYSKSLSGIALQVGEQIICGRYAENAAFNP
SFLPLQSALNYRRLSGKSDERISRIVMAESKGTTSHRQMSEALAESFLGLNLEYIEV
>Mature_296_residues
PTLFALKERIAQVVQEKNDPIVTAVATTLAEQQYNACFSAEQVKLWKRQFKCSSVELALACLPIAACYALVPISNFYVGA
VAIGESGRFYFGANQEFNAQAIQQTVHAEQSAISHAWLAGETAITDMVVNYTPCGHCRQFMNELNSAKTLKIHLPHSQNN
LLRQYLPDSFGPKDLNIEKVLFDQQTHSLPLRGDLLTQAAIQTAAQSYAPYSKSLSGIALQVGEQIICGRYAENAAFNPS
FLPLQSALNYRRLSGKSDERISRIVMAESKGTTSHRQMSEALAESFLGLNLEYIEV

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family

Homologues:

Organism=Escherichia coli, GI1788465, Length=251, Percent_Identity=54.1832669322709, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDD_ACTP2 (A3N1Z1)

Other databases:

- EMBL:   CP000569
- RefSeq:   YP_001054032.1
- ProteinModelPortal:   A3N1Z1
- SMR:   A3N1Z1
- STRING:   A3N1Z1
- GeneID:   4848536
- GenomeReviews:   CP000569_GR
- KEGG:   apl:APL_1343
- eggNOG:   COG0295
- HOGENOM:   HBG591160
- OMA:   NRSHAPY
- PhylomeDB:   A3N1Z1
- ProtClustDB:   PRK09027
- BioCyc:   APLE416269:APL_1343-MONOMER
- HAMAP:   MF_01558
- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR013171
- InterPro:   IPR006263
- InterPro:   IPR016193
- InterPro:   IPR020797
- PIRSF:   PIRSF006334

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF08211 dCMP_cyt_deam_2; SSF53927 Cytidine_deaminase-like

EC number: =3.5.4.5

Molecular weight: Translated: 32813; Mature: 32682

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: ACT_SITE 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLFALKERIAQVVQEKNDPIVTAVATTLAEQQYNACFSAEQVKLWKRQFKCSSVELAL
CCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ACLPIAACYALVPISNFYVGAVAIGESGRFYFGANQEFNAQAIQQTVHAEQSAISHAWLA
HHHHHHHHHHHHHHCCEEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHC
GETAITDMVVNYTPCGHCRQFMNELNSAKTLKIHLPHSQNNLLRQYLPDSFGPKDLNIEK
CCHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCHHH
VLFDQQTHSLPLRGDLLTQAAIQTAAQSYAPYSKSLSGIALQVGEQIICGRYAENAAFNP
HEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHCCHHHHCHHHCCCCCCC
SFLPLQSALNYRRLSGKSDERISRIVMAESKGTTSHRQMSEALAESFLGLNLEYIEV
CCHHHHHHHHHHHCCCCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure 
PTLFALKERIAQVVQEKNDPIVTAVATTLAEQQYNACFSAEQVKLWKRQFKCSSVELAL
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ACLPIAACYALVPISNFYVGAVAIGESGRFYFGANQEFNAQAIQQTVHAEQSAISHAWLA
HHHHHHHHHHHHHHCCEEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHC
GETAITDMVVNYTPCGHCRQFMNELNSAKTLKIHLPHSQNNLLRQYLPDSFGPKDLNIEK
CCHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCHHH
VLFDQQTHSLPLRGDLLTQAAIQTAAQSYAPYSKSLSGIALQVGEQIICGRYAENAAFNP
HEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHCCHHHHCHHHCCCCCCC
SFLPLQSALNYRRLSGKSDERISRIVMAESKGTTSHRQMSEALAESFLGLNLEYIEV
CCHHHHHHHHHHHCCCCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA